Brain specific Lamellipodin knockout results in hyperactivity and increased anxiety of mice

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Brain specific Lamellipodin knockout results in hyperactivity and increased anxiety of mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1090627101
P356DOI10.1038/S41598-017-05043-3
P932PMC publication ID5511208
P698PubMed publication ID28710397

P50authorCathy FernandesQ56678789
Matthias KrauseQ44831846
P2093author name stringCristian Bodo
P2860cites workHome-cage activity in heterogeneous stock (HS) mice as a model of baseline activityQ48242657
A phosphatidylinositol lipids system, lamellipodin, and Ena/VASP regulate dynamic morphology of multipolar migrating cells in the developing cerebral cortex.Q48401488
Test standardization in behavioural neuroscience: a response to Stanford.Q51993122
The Open Field Test: reinventing the wheelQ79847574
MIG-10/lamellipodin and AGE-1/PI3K promote axon guidance and outgrowth in response to slit and netrinQ83161524
Endophilin, Lamellipodin, and Mena cooperate to regulate F-actin-dependent EGF-receptor endocytosis.Q24337515
Lamellipodin promotes invasive 3D cancer cell migration via regulated interactions with Ena/VASP and SCAR/WAVE.Q27309896
Lamellipodin, an Ena/VASP ligand, is implicated in the regulation of lamellipodial dynamicsQ28286512
RIAM, an Ena/VASP and Profilin ligand, interacts with Rap1-GTP and mediates Rap1-induced adhesionQ28286523
PREL1 provides a link from Ras signalling to the actin cytoskeleton via Ena/VASP proteinsQ28301906
Mena is required for neurulation and commissure formationQ28588447
Performance deficit of alpha7 nicotinic receptor knockout mice in a delayed matching-to-place task suggests a mild impairment of working/episodic-like memoryQ28588757
c-Abl, Lamellipodin, and Ena/VASP proteins cooperate in dorsal ruffling of fibroblasts and axonal morphogenesisQ28589079
Lamellipodin and the Scar/WAVE complex cooperate to promote cell migration in vivoQ30557898
Rodent sex differences in emotional and related behaviorQ34041914
Behavioral and functional analysis of mouse phenotype: SHIRPA, a proposed protocol for comprehensive phenotype assessmentQ34441265
The mouse light/dark box testQ35071479
Lpd depletion reveals that SRF specifies radial versus tangential migration of pyramidal neurons.Q35146088
Opinion: Sex inclusion in basic research drives discoveryQ35566933
Netrin instructs synaptic vesicle clustering through Rac GTPase, MIG-10, and the actin cytoskeleton.Q35866197
Lamellipodin promotes actin assembly by clustering Ena/VASP proteins and tethering them to actin filamentsQ35979105
Role of Ena/VASP proteins in homeostasis and diseaseQ37168189
Drosophila pico and its mammalian ortholog lamellipodin activate serum response factor and promote cell proliferationQ37215670
Steering cell migration: lamellipodium dynamics and the regulation of directional persistenceQ38242035
Endophilin marks and controls a clathrin-independent endocytic pathway.Q38927789
Signaling specificity by Ras family GTPases is determined by the full spectrum of effectors they regulateQ40886507
Semaphorin 4D/Plexin-B1-mediated M-Ras GAP activity regulates actin-based dendrite remodeling through Lamellipodin.Q42508014
Critical role of Ena/VASP proteins for filopodia formation in neurons and in function downstream of netrin-1.Q44831766
UNC-6/netrin and SLT-1/slit guidance cues orient axon outgrowth mediated by MIG-10/RIAM/lamellipodin.Q47068983
Mutations affecting embryonic cell migrations in Caenorhabditis elegansQ47069580
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue1
P407language of work or nameEnglishQ1860
P304page(s)5365
P577publication date2017-07-14
P1433published inScientific ReportsQ2261792
P1476titleBrain specific Lamellipodin knockout results in hyperactivity and increased anxiety of mice
P478volume7

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Q89865464Lamellipodin tunes cell migration by stabilizing protrusions and promoting adhesion formationcites workP2860

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