Receptor tyrosine kinases and schistosome reproduction: new targets for chemotherapy

scientific article

Receptor tyrosine kinases and schistosome reproduction: new targets for chemotherapy is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.3389/FGENE.2014.00238
P932PMC publication ID4102852
P698PubMed publication ID25101117
P5875ResearchGate publication ID264193764

P50authorChristoph G GreveldingQ89899689
Marion MorelQ95984950
P2093author name stringColette Dissous
Steffen Hahnel
Mathieu Vanderstraete
P2860cites workControl of germline stem cell division frequency--a novel, developmentally regulated role for epidermal growth factor signalingQ21134586
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The Syk kinase SmTK4 of Schistosoma mansoni is involved in the regulation of spermatogenesis and oogenesisQ27315898
Signal transduction by receptors with tyrosine kinase activityQ27860624
The GLH proteins, Caenorhabditis elegans P granule components, associate with CSN-5 and KGB-1, proteins necessary for fertility, and with ZYX-1, a predicted cytoskeletal proteinQ27939791
Cloning and characterisation of Schistosoma japonicum insulin receptorsQ28473411
Reduced susceptibility to praziquantel among naturally occurring Kenyan isolates of Schistosoma mansoniQ28475935
Gene Atlasing of digestive and reproductive tissues in Schistosoma mansoniQ28477895
Discovery of platyhelminth-specific α/β-integrin families and evidence for their role in reproduction in Schistosoma mansoniQ28484597
Dual targeting of insulin and venus kinase Receptors of Schistosoma mansoni for novel anti-schistosome therapyQ28488169
Transcriptome analyses of inhibitor-treated schistosome females provide evidence for cooperating Src-kinase and TGFβ receptor pathways controlling mitosis and eggshell formationQ28533891
Whole-organ isolation approach as a basis for tissue-specific analyses in Schistosoma mansoniQ28534863
Imatinib treatment causes substantial transcriptional changes in adult Schistosoma mansoni in vitro exhibiting pleiotropic effectsQ28539623
The venus kinase receptor (VKR) family: structure and evolutionQ30636360
The Schistosoma mansoni Src kinase TK3 is expressed in the gonads and likely involved in cytoskeletal organizationQ31130817
Expression of functional Schistosoma mansoni Smad4: role in Erk-mediated transforming growth factor beta (TGF-beta) down-regulationQ33195224
Schistosoma mansoni TGF-beta receptor II: role in host ligand-induced regulation of a schistosome target geneQ33247465
TGF-beta signaling controls embryo development in the parasitic flatworm Schistosoma mansoniQ33281290
A new family of receptor tyrosine kinases with a venus flytrap binding domain in insects and other invertebrates activated by aminoacidsQ33450644
Tissue specific profiling of females of Schistosoma japonicum by integrated laser microdissection microscopy and microarray analysisQ33476140
Schistosoma mansoni: signal transduction processes during the development of the reproductive organsQ33531955
Venus kinase receptors control reproduction in the platyhelminth parasite Schistosoma mansoniQ33686019
Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs.Q33730904
Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoniQ33891612
Characterization of the Src/Abl hybrid kinase SmTK6 of Schistosoma mansoniQ34052174
Cell death and reproductive regression in female Schistosoma mansoniQ34171764
Schistosome male-female interaction: induction of germ-cell differentiationQ34232564
Schistosome female reproductive developmentQ34355383
Tyrphostins and other tyrosine kinase inhibitorsQ34535133
Escherichia coli- and Staphylococcus aureus-induced mastitis differentially modulate transcriptional responses in neighbouring uninfected bovine mammary gland quartersQ34550020
Signalling through IGF-I and insulin receptors: where is the specificity?Q34783548
Cytokine-mediated host responses during schistosome infections; walking the fine line between immunological control and immunopathologyQ35042634
Imatinib: a selective tyrosine kinase inhibitorQ35045448
Functional Diversity of the Schistosoma mansoni Tyrosine KinasesQ35101901
Evolution, structure, and activation mechanism of family 3/C G-protein-coupled receptorsQ35143358
Schistosoma mansoni: TGF-beta signaling pathwaysQ36291640
An insulin-like peptide regulates egg maturation and metabolism in the mosquito Aedes aegyptiQ36558126
Tyrosine kinase and cooperative TGFbeta signaling in the reproductive organs of Schistosoma mansoni.Q36842108
Protein tyrosine kinases as new potential targets against human schistosomiasisQ37006122
Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasisQ37315241
Signal transduction regulates schistosome reproductive biologyQ37339811
Growth factors controlling ovarian functionsQ37887631
Conservation of epidermal growth factor receptor function in the human parasitic helminth Schistosoma mansoniQ38339365
Herbimycin A suppresses mitotic activity and egg production of female Schistosoma mansoni.Q39141980
Alternative splicing of the Schistosoma mansoni gene encoding a homologue of epidermal growth factor receptorQ39459025
Cloning, characterization, and functional expression of cDNAs encoding glucose transporter proteins from the human parasite Schistosoma mansoni.Q39469507
Identification and characterization of a Smad2 homologue from Schistosoma mansoni, a transforming growth factor-beta signal transducerQ40832340
Insulin-mediated secretion of ecdysteroids from mosquito ovaries and molecular cloning of the insulin receptor homologue from ovaries of bloodfed Aedes aegyptiQ42982161
Imatinib has a fatal impact on morphology, pairing stability and survival of adult Schistosoma mansoni in vitroQ43165015
Human transforming growth factor-beta activates a receptor serine/threonine kinase from the intravascular parasite Schistosoma mansoniQ43640421
A novel Syk-family tyrosine kinase from Schistosoma mansoni which is preferentially transcribed in reproductive organs.Q44138295
Nutrient content of diet affects the signaling activity of the insulin/target of rapamycin/p70 S6 kinase pathway in the African malaria mosquito Anopheles gambiaeQ44142136
Quantification of DNA synthesis in multicellular organisms by a combined DAPI and BrdU technique.Q44256266
An unusual receptor tyrosine kinase of Schistosoma mansoni contains a Venus Flytrap module.Q44294289
Cytological and biochemical evidence for a gonad-preferential interplay of SmFKBP12 and SmTbetaR-I in Schistosoma mansoni.Q45157460
Schistosoma mansoni: structural and biochemical characterization of two distinct Venus Kinase Receptors.Q46034996
Insulin receptors and glucose uptake in the human parasite Schistosoma mansoniQ46128658
Functional conservation of Schistosoma mansoni Smads in TGF-beta signalingQ47812633
Genomic survey of premetazoans shows deep conservation of cytoplasmic tyrosine kinases and multiple radiations of receptor tyrosine kinases.Q47822018
Diversification of the insulin receptor family in the helminth parasite Schistosoma mansoni.Q47823208
A divergent member of the transforming growth factor beta receptor family from Schistosoma mansoni is expressed on the parasite surface membraneQ48037706
De novo synthesis of protein phosphatase 1A, magnesium dependent, alpha isoform (PPM1A) during oocyte maturation.Q48647571
JNK2 participates in spindle assembly during mouse oocyte meiotic maturationQ48682249
Modulation of MAPK activities during egg activation in DrosophilaQ48738127
The epidermal growth factor receptor and its ligands in female reproduction: insights from rodent modelsQ48763999
Reproductive development of female Schistosoma mansoni (Digenea: Schistosomatidae) following bisexual pairing of worms and worm segments.Q52272369
A comparative study of the reproductive system of mature, immature and "unisexual" female Schistosoma mansoni.Q54162318
Piggy-backing the concept of cancer drugs for schistosomiasis treatment: a tangible perspective?Q54646067
The insulin receptor is a transmission blocking veterinary vaccine target for zoonotic Schistosoma japonicumQ56768888
SchistosomiasisQ79806845
Schistosoma mansoni: male stimulation and DNA synthesis by the femaleQ93663782
P921main subjectchemotherapyQ974135
P304page(s)238
P577publication date2014-07-18
P1433published inFrontiers in GeneticsQ2499875
P1476titleReceptor tyrosine kinases and schistosome reproduction: new targets for chemotherapy
P478volume5

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cites work (P2860)
Q33755846Changes in the neuropeptide content of Biomphalaria ganglia nervous system following Schistosoma infection
Q37324933Comparison of ex vivo harvested and in vitro cultured materials from Echinococcus granulosus by measuring expression levels of five genes putatively involved in the development and maturation of adult worms.
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Q35593046Suppression of the Insulin Receptors in Adult Schistosoma japonicum Impacts on Parasite Growth and Development: Further Evidence of Vaccine Potential
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Q28543997The diterpenoid 7-keto-sempervirol, derived from Lycium chinense, displays anthelmintic activity against both Schistosoma mansoni and Fasciola hepatica
Q57159150Transcriptomic analysis of male and female Schistosoma mekongi adult worms

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