scholarly article | Q13442814 |
review article | Q7318358 |
P50 | author | Jürg Utzinger | Q28324256 |
Michael J. Doenhoff | Q41456714 | ||
P2093 | author name string | Donato Cioli | |
P2860 | cites work | Identification of an antimalarial synthetic trioxolane drug development candidate | Q22061876 |
P433 | issue | 6 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | schistosomiasis | Q221159 |
praziquantel | Q424145 | ||
P5008 | on focus list of Wikimedia project | ScienceSource | Q55439927 |
P304 | page(s) | 659-667 | |
P577 | publication date | 2008-12-01 | |
P1433 | published in | Current Opinion in Infectious Diseases | Q15724406 |
P1476 | title | Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis | |
P478 | volume | 21 |
Q99635896 | 30 years of parasitology research analysed by text mining |
Q52677297 | A Novel Class of Schistosoma mansoni Histone Deacetylase 8 (HDAC8) Inhibitors Identified by Structure-Based Virtual Screening and In Vitro Testing. |
Q89823709 | A Review of Nanotechnology for Targeted Anti-schistosomal Therapy |
Q39161231 | A catecholamine transporter from the human parasite Schistosoma mansoni with low affinity for psychostimulants. |
Q39091997 | A conventional polymerase chain reaction-based method for the diagnosis of human schistosomiasis in stool samples from individuals in a low-endemicity area |
Q37697955 | A multidisciplinary, integrated approach for the elimination of schistosomiasis: a longitudinal study in a historically hyper-endemic region in the lower reaches of the Yangtze River, China from 2005 to 2014 |
Q28476171 | A novel high throughput assay for anthelmintic drug screening and resistance diagnosis by real-time monitoring of parasite motility |
Q36247094 | A survey of schistosome protein domain types: insights into unique biological properties |
Q33486179 | A wake up call for urinary schistosomiasis: reconciling research effort with public health importance |
Q37053762 | ABC multidrug transporters in schistosomes and other parasitic flatworms |
Q37941754 | ABC transporters involved in drug resistance in human parasites. |
Q38123553 | Advocacy, policies and practicalities of preventive chemotherapy campaigns for African children with schistosomiasis |
Q39467299 | Algorithmic Mapping and Characterization of the Drug-Induced Phenotypic-Response Space of Parasites Causing Schistosomiasis |
Q91771868 | An Efficient Schistosoma japonicum Bivalent Membrane Protein Antigen DNA Vaccine Against Schistosomiasis in Mice |
Q28544852 | An artemisinin derivative of praziquantel as an orally active antischistosomal agent |
Q28545088 | Anthelmintic activity in vivo of epiisopiloturine against juvenile and adult worms of Schistosoma mansoni |
Q56909277 | Antibody Responses to Schistosoma mansoni Schistosomula Antigens |
Q36018841 | Antischistosomal activities of mefloquine-related arylmethanols |
Q37674908 | Antischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni worms |
Q40601229 | Antischistosomal activity of hederacochiside C against Schistosoma japonicum harbored in experimentally infected animals. |
Q28547348 | Application of RNAi to Genomic Drug Target Validation in Schistosomes |
Q60949181 | Artemether and Praziquantel: Origin, Mode of Action, Impact, and Suggested Application for Effective Control of Human Schistosomiasis |
Q42015454 | Artemisinin: the gifts from traditional Chinese medicine not only for malaria control but also for schistosomiasis control |
Q55228407 | Atypical pharmacology of schistosome TRPA1-like ion channels. |
Q62486477 | Benefits of annual chemotherapeutic control of schistosomiasis on the development of protective immunity |
Q83769924 | Bioavailability and in vivo efficacy of a praziquantel-polyvinylpyrrolidone solid dispersion in Schistosoma mansoni-infected mice |
Q38004814 | Biogenic amines and the control of neuromuscular signaling in schistosomes |
Q38035721 | Cerebral and spinal schistosomiasis |
Q37651018 | Characterization of Schistosoma japonicum CP1412 protein as a novel member of the ribonuclease T2 molecule family with immune regulatory function |
Q34052174 | Characterization of the Src/Abl hybrid kinase SmTK6 of Schistosoma mansoni |
Q43701919 | Characterization of the cGMP-dependent protein kinase SmcGK1 of Schistosoma mansoni |
Q36802409 | Characterization of the methionine sulfoxide reductases of Schistosoma mansoni |
Q55604560 | Cheminformatics models for inhibitors of Schistosoma mansoni thioredoxin glutathione reductase. |
Q38630566 | Clinical implications of recent findings in schistosome proteomics |
Q36884691 | Cloning and functional characterization of two calmodulin genes during larval development in the parasitic flatworm Schistosoma mansoni |
Q34675128 | Combined TLR7/8 and TLR9 ligands potentiate the activity of a Schistosoma japonicum DNA vaccine |
Q37680707 | Community knowledge, attitudes and practices on schistosomiasis in western Kenya--the SCORE Project |
Q41758770 | Comparative biochemical analysis of three members of the Schistosoma mansoni TAL family: Differences in ion and drug binding properties |
Q34705499 | Comparative pharmacology of flatworm and roundworm glutamate-gated chloride channels: Implications for potential anthelmintics |
Q34629346 | Comparing parasitological vs serological determination of Schistosoma haematobium infection prevalence in preschool and primary school-aged children: implications for control programmes |
Q34705415 | Compound library screening identified Akt/PKB kinase pathway inhibitors as potential key molecules for the development of new chemotherapeutics against schistosomiasis. |
Q55000698 | Compounds from African Medicinal Plants with Activities Against Selected Parasitic Diseases: Schistosomiasis, Trypanosomiasis and Leishmaniasis. |
Q37463234 | Conquering 'snail fever': schistosomiasis and its control in China. |
Q40173400 | Conservation of protein kinase a catalytic subunit sequences in the schistosome pathogens of humans |
Q46964347 | Control of schistosomiasis in sub-Saharan Africa: progress made, new opportunities and remaining challenges. |
Q37771992 | Controlling schistosomiasis in Southeast Asia: a tale of two countries |
Q37726920 | Controlling schistosomiasis with praziquantel: How much longer without a viable alternative? |
Q37565174 | CpG oligodeoxynucleotide ligand potentiates the activity of the pVAX1-Sj26GST. |
Q89920010 | Current and Novel Therapies Against Helminthic Infections: The Potential of Antioxidants Combined with Drugs |
Q38093067 | Current drug targets for helminthic diseases |
Q37682900 | DNA vaccines: a rational design against parasitic diseases. |
Q36679169 | De novo transcriptomic analysis of the female and male adults of the blood fluke Schistosoma turkestanicum |
Q36346161 | Defining the Schistosoma haematobium kinome enables the prediction of essential kinases as anti-schistosome drug targets |
Q57822205 | Design, Synthesis, and Characterization of Novel Small Molecules as Broad Range Antischistosomal Agents |
Q39004176 | Design, synthesis and biological evaluation of praziquantel and endoperoxide conjugates as antischistosomal agents |
Q46243865 | Detection of duo-schistosome infection from filtered urine samples from school children in Zambia after MDA. |
Q28483732 | Determining treatment needs at different spatial scales using geostatistical model-based risk estimates of schistosomiasis |
Q36219372 | Development of an in vitro drug screening assay using Schistosoma haematobium schistosomula |
Q35590947 | Diagnosis and management of schistosomiasis |
Q38152776 | Diagnosis and treatment of schistosomiasis in children in the era of intensified control |
Q39175318 | Dihydroartemisinin: a new story of an old drug against Schistosoma mansoni infection |
Q36275312 | Dihydrobenz[e][1,4]oxazepin-2(3H)-ones, a new anthelmintic chemotype immobilising whipworm and reducing infectivity in vivo |
Q28553478 | Discovery and Characterization of Novel Anti-schistosomal Properties of the Anti-anginal Drug, Perhexiline and Its Impact on Schistosoma mansoni Male and Female Reproductive Systems |
Q42680012 | Discovery by organism based high-throughput screening of new multi-stage compounds affecting Schistosoma mansoni viability, egg formation and production. |
Q33781930 | Does granulocyte-colony stimulating factor administration induce damage or repair response in schistosomiasis? |
Q52672813 | Dose-response relationship in Schistosoma mansoni juvenile and adult stages following limonin treatment in experimentally infected mice. |
Q52699502 | Drug Repurposing for Schistosomiasis: Combinations of Drugs or Biomolecules. |
Q99719959 | Drug metabolism and pharmacokinetics of praziquantel: A review of variable drug exposure during schistosomiasis treatment in human hosts and experimental models |
Q38495057 | Drugging the schistosome zinc-dependent HDACs: current progress and future perspectives |
Q24201000 | Drugs for treating Schistosoma mansoni infection |
Q24194447 | Drugs for treating urinary schistosomiasis |
Q36572029 | Dynamics of Schistosoma haematobium egg output and associated infection parameters following treatment with praziquantel in school-aged children |
Q50781056 | Effect of Mirazid in Schistosoma japonicum-infected mice: parasitological and pathological assessment. |
Q39338872 | Effect of a novel benzimidazole derivative in experimental Schistosoma mansoni infection. |
Q38974529 | Effect of gold nanoparticles on mice splenomegaly induced by schistosomiasis mansoni |
Q47872179 | Effect of ozonide OZ418 against Schistosoma japonicum harbored in mice |
Q33449456 | Effect of single-dose oral mefloquine on the morphology of adult Schistosoma japonicum in mice |
Q47998506 | Effectiveness of synthetic trioxolane OZ78 against Schistosoma japonicum in mice and rabbits |
Q51456665 | Effects of artemether, artesunate and dihydroartemisinin administered orally at multiple doses or combination in treatment of mice infected with Schistosoma japonicum. |
Q57116125 | Effects of miconazole/clotrimazole and praziquantel combinations against the liver fluke Opisthorchis felineus in vivo and in vitro |
Q92238880 | Effects of the Environment on Developmental Plasticity and Infection Success of Schistosoma Parasites - An Epigenetic Perspective |
Q39439977 | Efficacious and safe dose of praziquantel for the successful treatment of feline reservoir hosts with opisthorchiasis |
Q47094509 | Efficacy and safety of praziquantel against Schistosoma haematobium in the Ikata-Likoko area of southwest Cameroon |
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Q57805340 | Efficacy comparison between long-term high-dose praziquantel and surgical therapy for cerebral sparganosis: A multicenter retrospective cohort study |
Q34081597 | Efficacy of Essential Oils of Thymus vulgaris and Origanum vulgare on Echinococcus granulosus |
Q92892485 | Efficacy of Ozoroa pulcherrima Schweinf methanolic extract against Schistosoma mansoni-induced liver injury in mice |
Q39576151 | Efficacy of artemether and artesunate in mice infected with praziquantel non-susceptible isolate of Schistosoma japonicum |
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Q33528954 | Electroporation facilitates introduction of reporter transgenes and virions into schistosome eggs. |
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Q34159188 | Epigenetic control of gene function in schistosomes: a source of therapeutic targets? |
Q33891612 | Eukaryotic protein kinases (ePKs) of the helminth parasite Schistosoma mansoni |
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Q38966422 | Evaluation of the in vitro activity of dermaseptin 01, a cationic antimicrobial peptide, against Schistosoma mansoni |
Q27303844 | Evidence for Novel Pharmacological Sensitivities of Transient Receptor Potential (TRP) Channels in Schistosoma mansoni |
Q39574584 | Exosome-like vesicles derived by Schistosoma japonicum adult worms mediates M1 type immune- activity of macrophage |
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Q37694858 | Expression at a 20L scale and purification of the extracellular domain of the Schistosoma mansoni TSP-2 recombinant protein: a vaccine candidate for human intestinal schistosomiasis |
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Q37787339 | From innovation to application: Social–ecological context, diagnostics, drugs and integrated control of schistosomiasis |
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Q28478288 | Genetic knockdown and pharmacological inhibition of parasite multidrug resistance transporters disrupts egg production in Schistosoma mansoni |
Q37282903 | Genomic linkage map of the human blood fluke Schistosoma mansoni |
Q28481592 | Germline transgenesis and insertional mutagenesis in Schistosoma mansoni mediated by murine leukemia virus |
Q33730904 | Gonad RNA-specific qRT-PCR analyses identify genes with potential functions in schistosome reproduction such as SmFz1 and SmFGFRs. |
Q38205649 | HIV and schistosomiasis co-infection in African children |
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Q33745207 | Health seeking behaviour and utilization of health facilities for schistosomiasis-related symptoms in Ghana |
Q28551698 | High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni |
Q46120029 | Histopathological changes in adult Schistosoma japonicum harbored in mice treated with a single dose of mefloquine |
Q30245056 | History of schistosomiasis epidemiology, current status, and challenges in China: on the road to schistosomiasis elimination |
Q34413522 | Human schistosomiasis |
Q28476429 | IL-10 blocks the development of resistance to re-infection with Schistosoma mansoni |
Q33908196 | Identification of G protein-coupled receptors in Schistosoma haematobium and S. mansoni by comparative genomics |
Q60932082 | Identification of novel multi-stage histone deacetylase (HDAC) inhibitors that impair Schistosoma mansoni viability and egg production |
Q37675128 | Imatinib activity on Schistosoma mansoni |
Q28539623 | Imatinib treatment causes substantial transcriptional changes in adult Schistosoma mansoni in vitro exhibiting pleiotropic effects |
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Q28551003 | Impact of Annual Praziquantel Treatment on Urogenital Schistosomiasis in a Seasonal Transmission Focus in Central Senegal |
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Q37292213 | In Vitro Schistosomicidal Activity of Phytol and Tegumental Alterations Induced in Juvenile and Adult Stages of Schistosoma haematobium |
Q60924844 | In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets |
Q28542999 | In silico repositioning-chemogenomics strategy identifies new drugs with potential activity against multiple life stages of Schistosoma mansoni |
Q38648427 | In vitro and in vivo activity of R- and S- praziquantel enantiomers and the main human metabolite trans-4-hydroxy-praziquantel against Schistosoma haematobium |
Q27339703 | In vitro and in vivo anti-schistosomal activity of the alkylphospholipid analog edelfosine |
Q51301728 | In vitro evaluation of schistosomicidal potential of curcumin against Schistosoma japonicum. |
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Q27304398 | Inhibition of Granulomatous Inflammation and Prophylactic Treatment of Schistosomiasis with a Combination of Edelfosine and Praziquantel |
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Q28543846 | Inhibition or knockdown of ABC transporters enhances susceptibility of adult and juvenile schistosomes to Praziquantel |
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Q28474353 | Mefloquine--an aminoalcohol with promising antischistosomal properties in mice |
Q92919048 | Modifications of histones in parasites as drug targets |
Q33552868 | Modulation of a Schistosoma mansoni multidrug transporter by the antischistosomal drug praziquantel |
Q51213476 | Molecular and structural characteristics of multidrug resistance-associated protein 7 in Chinese liver fluke Clonorchis sinensis. |
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Q36089897 | Molecular docking to explore the possible binding mode of potential inhibitors of thioredoxin glutathione reductase |
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Q36656087 | Natural products as a source for treating neglected parasitic diseases |
Q33745561 | Neuroschistosomiasis |
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