Design, synthesis and biological evaluation of praziquantel and endoperoxide conjugates as antischistosomal agents

scientific article published on January 2015

Design, synthesis and biological evaluation of praziquantel and endoperoxide conjugates as antischistosomal agents is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.4155/FMC.15.20
P698PubMed publication ID25996065
P5875ResearchGate publication ID277082396

P2093author name stringShilin Yang
Anne Rognon
Chunhua Qiao
Jing-jing Yang
Houzong Yao
Jerome Boissier
Jing-Lei Chen
P2860cites workAntischistosomal activity of trioxaquines: in vivo efficacy and mechanism of action on Schistosoma mansoniQ28480620
Structure-activity relationship of an ozonide carboxylic acid (OZ78) against Fasciola hepaticaQ33899023
Synthetic ozonide drug candidate OZ439 offers new hope for a single-dose cure of uncomplicated malariaQ34693880
Abnormal pulmonary function and respiratory muscle strength findings in Chinese patients with Parkinson's disease and multiple system atrophy--comparison with normal elderlyQ34784683
In vitro and in vivo activities of synthetic trioxolanes against major human schistosome speciesQ35758795
Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasisQ37315241
Rational approaches, design strategies, structure activity relationship and mechanistic insights for anticancer hybrids.Q38200833
Recent approaches to chemical discovery and development against malaria and the neglected tropical diseases human African trypanosomiasis and schistosomiasisQ38228453
Are poor responses to praziquantel for the treatment of Schistosoma mansoni infections in Senegal due to resistance? An overview of the evidence.Q39034640
Synthesis and evaluation of the antimalarial, anticancer, and caspase 3 activities of tetraoxane dimers.Q39073626
Ferrocenyl derivatives of the anthelmintic praziquantel: design, synthesis, and biological evaluation.Q39272956
Praziquantel analogs with activity against juvenile Schistosoma mansoniQ43123274
In vitro metabolic profile and in vivo antischistosomal activity studies of (η(6)-praziquantel)Cr(CO)3 derivativesQ44591248
P433issue6
P407language of work or nameEnglishQ1860
P921main subjectpraziquantelQ424145
P304page(s)713-725
P577publication date2015-01-01
P1433published inFuture Medicinal ChemistryQ19280078
P1476titleDesign, synthesis and biological evaluation of praziquantel and endoperoxide conjugates as antischistosomal agents
P478volume7

Reverse relations

cites work (P2860)
Q47664127Peroxides with Anthelmintic, Antiprotozoal, Fungicidal and Antiviral Bioactivity: Properties, Synthesis and Reactions.
Q39164325Praziquantel for Schistosomiasis: Single-Drug Metabolism Revisited, Mode of Action, and Resistance.
Q90859559Schistosomiasis

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