Characterization of Schistosoma japonicum CP1412 protein as a novel member of the ribonuclease T2 molecule family with immune regulatory function

scientific article published on 17 February 2017

Characterization of Schistosoma japonicum CP1412 protein as a novel member of the ribonuclease T2 molecule family with immune regulatory function is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1083847182
P356DOI10.1186/S13071-016-1962-Y
P932PMC publication ID5316207
P698PubMed publication ID28212670

P50authorMihoko KikuchiQ96254031
P2093author name stringHong Gao
Jie Wang
Wei Zhou
Qian Liu
Yuan Yao
Shuang Shen
Kenji Hirayama
Li-Jun Song
Chuan-Xin Yu
Xue-Dan Ke
Xuren Yin
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Alternative activation of macrophages: mechanism and functionsQ29614350
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Schistosome-derived omega-1 drives Th2 polarization by suppressing protein synthesis following internalization by the mannose receptorQ30525273
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The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)Q37292806
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Induction of antigen-specific immune tolerance by TGF-beta-induced CD4+Foxp3+ regulatory T cellsQ37405038
Parasitic antigens alter macrophage polarization during Schistosoma japonicum infection in mice.Q37684183
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The dendritic cell-specific C-type lectin DC-SIGN is a receptor for Schistosoma mansoni egg antigens and recognizes the glycan antigen Lewis x.Q38356935
The immunomodulatory glycan LNFPIII initiates alternative activation of murine macrophages in vivoQ40108993
A novel host-parasite lipid cross-talk. Schistosomal lyso-phosphatidylserine activates toll-like receptor 2 and affects immune polarizationQ40700194
Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pyloriQ43283512
Immunomodulation via novel use of TLR4 by the filarial nematode phosphorylcholine-containing secreted product, ES-62.Q44268237
Differentiation of Tr1 cells by immature dendritic cells requires IL-10 but not CD25+CD4+ Tr cellsQ45878833
IPSE/alpha-1: a major immunogenic component secreted from Schistosoma mansoni eggs.Q48099622
Molecular characterization of omega-1: a hepatotoxic ribonuclease from Schistosoma mansoni eggs.Q48123006
Phosphorylcholine mimics the effects of ES-62 on macrophages and dendritic cells.Q54559083
Identification and partial purification of an antigen (ω1 from Schistosoma mansoni eggs which is putatively hepatotoxic in T-cell deprived miceQ56835807
The purification, characterization, serological activity and hepatotoxic properties of two cationic glycoproteins (α1 and ω1) from Schistosoma mansoni eggsQ58312940
Egg deposition is the major stimulus for the production of Th2 cytokines in murine schistosomiasis mansoniQ67897545
Induction of T helper cell unresponsiveness to antigen by macrophages from schistosomal egg granulomas. A basis for immunomodulation in schistosomiasis?Q68429198
Induction of Th2 responses and IgE is largely due to carbohydrates functioning as adjuvants on Schistosoma mansoni egg antigensQ73242473
Helminth antigens modulate TLR-initiated dendritic cell activationQ81111451
Naturally occurring CD4+Foxp3+ regulatory T cells are an essential, IL-10-independent part of the immunoregulatory network in Schistosoma mansoni egg-induced inflammationQ83170053
Regulatory T cell responses develop in parallel to Th responses and control the magnitude and phenotype of the Th effector populationQ83276308
P433issue1
P921main subjectSchistosoma japonicumQ1256989
P304page(s)89
P577publication date2017-02-17
P1433published inParasites and VectorsQ7135941
P1476titleCharacterization of Schistosoma japonicum CP1412 protein as a novel member of the ribonuclease T2 molecule family with immune regulatory function
P478volume10

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cites work (P2860)
Q59792550Modulation of Host Immunity by Helminths: The Expanding Repertoire of Parasite Effector Molecules
Q61816687Programmed genome editing of the omega-1 ribonuclease of the blood fluke,
Q64110141Qualitative and quantitative proteomic analyses of Schistosoma japonicum eggs and egg-derived secretory-excretory proteins

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