Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development.

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Myc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development. is …
instance of (P31):
scholarly articleQ13442814

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P819ADS bibcode2005PNAS..10211799B
P356DOI10.1073/PNAS.0408945102
P932PMC publication ID1187951
P698PubMed publication ID16087886
P5875ResearchGate publication ID7672178

P50authorPaola BellostaQ54112910
P2093author name stringPeter Gallant
Denise Aragnol
Jacques Pradel
Soda Balla Diop
Fabrice Usseglio
Toby Hulf
P2860cites workPontin52, an interaction partner of beta-catenin, binds to the TATA box binding proteinQ22008488
TIP49b, a new RuvB-like DNA helicase, is included in a complex together with another RuvB-like DNA helicase, TIP49aQ22253154
Involvement of the TIP60 histone acetylase complex in DNA repair and apoptosisQ24290159
The novel ATM-related protein TRRAP is an essential cofactor for the c-Myc and E2F oncoproteinsQ24328753
TIP49b, a regulator of activating transcription factor 2 response to stress and DNA damageQ24514481
MYC recruits the TIP60 histone acetyltransferase complex to chromatinQ24535721
BAF53 forms distinct nuclear complexes and functions as a critical c-Myc-interacting nuclear cofactor for oncogenic transformationQ24537695
Pontin52 and reptin52 function as antagonistic regulators of beta-catenin signalling activityQ24597019
The ATM-related domain of TRRAP is required for histone acetyltransferase recruitment and Myc-dependent oncogenesisQ24601182
Genomic targets of the human c-Myc proteinQ24672480
An integrated database of genes responsive to the Myc oncogenic transcription factor: identification of direct genomic targetsQ24792966
Rvb1p and Rvb2p are essential components of a chromatin remodeling complex that regulates transcription of over 5% of yeast genesQ27931274
A chromatin remodelling complex involved in transcription and DNA processing.Q27932458
Impairment of the DNA binding activity of the TATA-binding protein renders the transcriptional function of Rvb2p/Tih2p, the yeast RuvB-like protein, essential for cell growthQ27937554
The Saccharomyces cerevisiae RuvB-like protein, Tih2p, is required for cell cycle progression and RNA polymerase II-directed transcriptionQ27937940
Rvb1p/Rvb2p recruit Arp5p and assemble a functional Ino80 chromatin remodeling complexQ27938536
c-MYC interacts with INI1/hSNF5 and requires the SWI/SNF complex for transactivation functionQ28143677
Control of nutrient-sensitive transcription programs by the unconventional prefoldin URIQ28184288
TIP49, but not TRRAP, modulates c-Myc and E2F1 dependent apoptosisQ28566674
Analysis of genetic mosaics in developing and adult Drosophila tissuesQ29617838
Whole-genome analysis reveals a strong positional bias of conserved dMyc-dependent E-boxesQ33758260
An ATPase/helicase complex is an essential cofactor for oncogenic transformation by c-MycQ33908306
Molecular cloning of a rat 49-kDa TBP-interacting protein (TIP49) that is highly homologous to the bacterial RuvB.Q34430067
The myc oncogene: MarvelouslY ComplexQ34555987
Genomic binding by the Drosophila Myc, Max, Mad/Mnt transcription factor networkQ35965143
The receptor tyrosine kinase ARK mediates cell aggregation by homophilic bindingQ36566375
c-Myc mediates activation of the cad promoter via a post-RNA polymerase II recruitment mechanismQ38295485
dMyc is required for larval growth and endoreplication in DrosophilaQ38341569
Myc and Max homologs in DrosophilaQ38351278
Proteins of the Myc network: essential regulators of cell growth and differentiation.Q41035974
Reptin and pontin antagonistically regulate heart growth in zebrafish embryos.Q44237320
A Drosophila RNA helicase gene, pitchoune, is required for cell growth and proliferation and is a potential target of d-MycQ47070623
Drosophila myc regulates organ size by inducing cell competitionQ47071644
dMyc transforms cells into super-competitorsQ47072112
Cell-autonomous and non-autonomous growth-defective mutants of Drosophila melanogasterQ47072319
Analysis of genomic targets reveals complex functions of MYC.Q47259237
Pontin and Reptin regulate cell proliferation in early Xenopus embryos in collaboration with c-Myc and Miz-1.Q52053549
A P-insertion screen identifying novel X-linked essential genes in Drosophila.Q52126589
Drosophila myc regulates cellular growth during development.Q52573250
Polycomb group proteins and heritable silencing of Drosophila Hox genes.Q52586295
A Drosophila Polycomb group complex includes Zeste and dTAFII proteins.Q52590226
A matter of life and deathQ63408384
P433issue33
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
Pontin Dmel_CG4003Q29815805
Reptin Dmel_CG9750Q29819520
Myc Dmel_CG10798Q29819672
P304page(s)11799-11804
P577publication date2005-08-08
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleMyc interacts genetically with Tip48/Reptin and Tip49/Pontin to control growth and proliferation during Drosophila development
P478volume102

Reverse relations

cites work (P2860)
Q33708357A Divergent Substrate-Binding Loop within the Pro-oncogenic Protein Anterior Gradient-2 Forms a Docking Site for Reptin
Q38429180An in vivo genetic screen in Drosophila identifies the orthologue of human cancer/testis gene SPO11 among a network of targets to inhibit lethal(3)malignant brain tumour growth
Q33640246Discovery of new membrane-associated proteins overexpressed in small-cell lung cancer
Q51776110Downregulation of RUVBL1 inhibits proliferation of lung adenocarcinoma cells by G1/S phase cell cycle arrest via multiple mechanisms.
Q34400766Drosophila Myc interacts with host cell factor (dHCF) to activate transcription and control growth
Q37621011Drosophila Myc.
Q34873737Drosophila Myc: A master regulator of cellular performance
Q36569851Drosophila growth and development in the absence of dMyc and dMnt
Q34032753Drosophila insulin and target of rapamycin (TOR) pathways regulate GSK3 beta activity to control Myc stability and determine Myc expression in vivo
Q34605623Genome-scale RNAi on living-cell microarrays identifies novel regulators of Drosophila melanogaster TORC1-S6K pathway signaling
Q35097100Genome-wide RNAi screen identifies broadly-acting host factors that inhibit arbovirus infection
Q64072005Gfi1b regulates the level of Wnt/β-catenin signaling in hematopoietic stem cells and megakaryocytes
Q30441323Human Rvb1/Tip49 is required for the histone acetyltransferase activity of Tip60/NuA4 and for the downregulation of phosphorylation on H2AX after DNA damage
Q37233375Identification of domains responsible for ubiquitin-dependent degradation of dMyc by glycogen synthase kinase 3beta and casein kinase 1 kinases
Q30505168Identification of gene expression changes associated with the initiation of diapause in the brain of the cotton bollworm, Helicoverpa armigera
Q47072146Induction of apoptosis by Drosophila Myc.
Q35700903Inhibition of Daughterless by Extramacrochaetae mediates Notch-induced cell proliferation
Q37709754Lytic water dynamics reveal evolutionarily conserved mechanisms of ATP hydrolysis by TIP49 AAA+ ATPases.
Q47367365MYC leads the way.
Q39306981MYC-Master Regulator of the Cancer Epigenome and Transcriptome
Q47071837Max-independent functions of Myc in Drosophila melanogaster
Q36578696Mechanism of transcriptional activation by the Myc oncoproteins
Q34291633Myc Function in Drosophila
Q58196742Myc and the Tip60 chromatin remodeling complex control neuroblast maintenance and polarity in
Q52760873Myc function in Drosophila.
Q33838577Oncogenic protein MTBP interacts with MYC to promote tumorigenesis
Q38310344Pontin is a critical regulator for AML1-ETO-induced leukemia
Q43161363Pontin is localized in nucleolar fibrillar centers
Q58700554Pontin/Tip49 acts as a novel regulator of JNK pathway
Q90651764Pontin/Tip49 negatively regulates JNK-mediated cell death in Drosophila
Q39405071RUVBL2 is a novel repressor of ARF transcription
Q30435879RVB1/RVB2: running rings around molecular biology
Q48105753Ras/ERK-signalling promotes tRNA synthesis and growth via the RNA polymerase III repressor Maf1 in Drosophila
Q36739922Regulation of microtubule assembly and organization in mitosis by the AAA+ ATPase Pontin
Q33921644Reptin is required for the transcription of telomerase reverse transcriptase and over-expressed in gastric cancer
Q37687097Rvb1-Rvb2: essential ATP-dependent helicases for critical complexes.
Q88372681The EGF/Ras pathway controls growth in Drosophila via ribosomal RNA synthesis
Q41539424The Role of Pontin and Reptin in Cellular Physiology and Cancer Etiology
Q33737444The Stearoyl-CoA Desaturase-1 (Desat1) in Drosophila cooperated with Myc to Induce Autophagy and Growth, a Potential New Link to Tumor Survival
Q24680747The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
Q90050086The True Story of Yeti, the "Abominable" Heterochromatic Gene of Drosophila melanogaster
Q37013896The c-myc promoter: still MysterY and challenge
Q36903188The estrogen-regulated anterior gradient 2 (AGR2) protein in breast cancer: a potential drug target and biomarker
Q30494710The lethal giant larvae tumour suppressor mutation requires dMyc oncoprotein to promote clonal malignancy
Q37398625The role of INI1/hSNF5 in gene regulation and cancer
Q43233345Widespread regulation of gene expression in the Drosophila genome by the histone acetyltransferase dTip60.
Q37015808dMyc expression in the fat body affects DILP2 release and increases the expression of the fat desaturase Desat1 resulting in organismal growth

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