Amino acids in positions 48, 52, and 73 differentiate the substrate specificities of the highly homologous chlorocatechol 1,2-dioxygenases CbnA and TcbC.

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Amino acids in positions 48, 52, and 73 differentiate the substrate specificities of the highly homologous chlorocatechol 1,2-dioxygenases CbnA and TcbC. is …
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P356DOI10.1128/JB.187.15.5427-5436.2005
P932PMC publication ID1196051
P698PubMed publication ID16030237

P50authorToshiya SendaQ58326815
P2093author name stringKiyotaka Miyashita
Naoto Ogawa
Akira Hasebe
Shenghao Liu
P2860cites workCrystal structure of 4-chlorocatechol 1,2-dioxygenase from the chlorophenol-utilizing gram-positive Rhodococcus opacus 1CP.Q44827069
Genetic characterization of insertion sequence ISJP4 on plasmid pJP4 from Ralstonia eutropha JMP134.Q48041137
Characterization of isofunctional ring-cleaving enzymes in aniline and 3-chloroaniline degradation by Pseudomonas acidovorans CA28Q67576651
Nucleotide homology and organization of chlorocatechol oxidation genes of plasmids pJP4 and pAC27Q69819367
Chlorocatechol 1,2-dioxygenase from Rhodococcus erythropolis 1CP. Kinetic and immunochemical comparison with analogous enzymes from gram-negative strainsQ72389648
A novel plasmid pIJB1 possessing a putative 2,4-dichlorophenoxyacetate degradative transposon Tn5530 in Burkholderia cepacia strain 2aQ74352495
Development of hybrid strains for the mineralization of chloroaromatics by patchwork assemblyQ77803447
Improved M13 phage cloning vectors and host strains: nucleotide sequences of the M13mp18 and pUC19 vectorsQ26778475
The 1.8 A crystal structure of catechol 1,2-dioxygenase reveals a novel hydrophobic helical zipper as a subunit linkerQ27622422
Structure of Acinetobacter strain ADP1 protocatechuate 3, 4-dioxygenase at 2.2 A resolution: implications for the mechanism of an intradiol dioxygenaseQ27625306
Dioxygen Activation by Enzymes with Mononuclear Non-Heme Iron Active SitesQ28201847
Chemical structure and biodegradability of halogenated aromatic compounds. Two catechol 1,2-dioxygenases from a 3-chlorobenzoate-grown pseudomonadQ28276220
Overproduction, purification, and characterization of chlorocatechol dioxygenase, a non-heme iron dioxygenase with broad substrate toleranceQ28321416
Cloning and characterization of plasmid-encoded genes for the degradation of 1,2-dichloro-, 1,4-dichloro-, and 1,2,4-trichlorobenzene of Pseudomonas sp. strain P51Q28334620
Sequence analysis of the Pseudomonas sp. strain P51 tcb gene cluster, which encodes metabolism of chlorinated catechols: evidence for specialization of catechol 1,2-dioxygenases for chlorinated substratesQ28335321
Chlorocatechols substituted at positions 4 and 5 are substrates of the broad-spectrum chlorocatechol 1,2-dioxygenase of Pseudomonas chlororaphis RW71Q28351206
Degradation of 1,2-dichlorobenzene by a Pseudomonas spQ28361308
Bacterial metabolism of 2,4-dichlorophenoxyacetateQ28364863
Degradation of 1,2,3,4-tetrachlorobenzene by pseudomonas chlororaphis RW71Q28369054
Degradation of 1,4-dichlorobenzene by Xanthobacter flavus 14p1Q28378740
High efficiency transformation of Escherichia coli with plasmidsQ29616589
A transposon encoding the complete 2,4-dichlorophenoxyacetic acid degradation pathway in the alkalitolerant strain Delftia acidovorans P4a.Q30979290
The chlorobenzoate dioxygenase genes of Burkholderia sp. strain NK8 involved in the catabolism of chlorobenzoatesQ31843099
The chlorocatechol-catabolic transposon Tn5707 of Alcaligenes eutrophus NH9, carrying a gene cluster highly homologous to that in the 1,2,4-trichlorobenzene-degrading bacterium Pseudomonas sp. strain P51, confers the ability to grow on 3-chlorobenzoQ33984281
Differential expression of two catechol 1,2-dioxygenases in Burkholderia sp. strain TH2.Q34436435
Organization and nucleotide sequence determination of a gene cluster involved in 3-chlorocatechol degradationQ34634784
Recombination of a 3-chlorobenzoate catabolic plasmid from Alcaligenes eutrophus NH9 mediated by direct repeat elementsQ35186714
Molecular mechanisms of genetic adaptation to xenobiotic compoundsQ35655423
Metabolism of and inhibition by chlorobenzoates in Pseudomonas putida P111.Q35727715
Organization and sequence analysis of the 2,4-dichlorophenol hydroxylase and dichlorocatechol oxidative operons of plasmid pJP4Q36161998
Plasmid specifying total degradation of 3-chlorobenzoate by a modified ortho pathway.Q36318146
Properties of six pesticide degradation plasmids isolated from Alcaligenes paradoxus and Alcaligenes eutrophusQ36321238
Genetic homology between independently isolated chlorobenzoate-degradative plasmidsQ36325675
Degradation of 1,4-dichlorobenzene by Alcaligenes sp. strain A175.Q36668269
Classification of catechol 1,2-dioxygenase family: sequence analysis of a gene for the catechol 1,2-dioxygenase showing high specificity for methylcatechols from Gram+ aniline-assimilating Rhodococcus erythropolis AN-13.Q36846679
Genetic analysis of phenoxyalkanoic acid degradation in Sphingomonas herbicidovorans MH.Q37572327
The completely sequenced plasmid pEST4011 contains a novel IncP1 backbone and a catabolic transposon harboring tfd genes for 2,4-dichlorophenoxyacetic acid degradationQ37583361
Conversion of 3-chlorocatechol by various catechol 2,3-dioxygenases and sequence analysis of the chlorocatechol dioxygenase region of Pseudomonas putida GJ31.Q38501491
Evolutionary relationship between chlorocatechol catabolic enzymes from Rhodococcus opacus 1CP and their counterparts in proteobacteria: sequence divergence and functional convergence.Q39564783
Int-B13, an unusual site-specific recombinase of the bacteriophage P4 integrase family, is responsible for chromosomal insertion of the 105-kilobase clc element of Pseudomonas sp. Strain B13.Q39568257
Importance of different tfd genes for degradation of chloroaromatics by Ralstonia eutropha JMP134Q39679890
Characterization of catechol catabolic genes from Rhodococcus erythropolis 1CPQ39844012
Identification and characterization of a new plasmid carrying genes for degradation of 2,4-dichlorophenoxyacetate from Pseudomonas cepacia CSV90.Q39913932
Formation of chlorocatechol meta cleavage products by a pseudomonad during metabolism of monochlorobiphenylsQ39915790
Degradation of 1,4-dichlorobenzene by a Pseudomonas spQ39924754
Transposon mutagenesis and cloning analysis of the pathways for degradation of 2,4-dichlorophenoxyacetic acid and 3-chlorobenzoate in Alcaligenes eutrophus JMP134(pJP4).Q39966254
Microbial metabolism of haloaromatics: isolation and properties of a chlorobenzene-degrading bacterium.Q40058150
The beta-ketoadipate pathway and the biology of self-identityQ41199628
Metabolism of 3-chloro-, 4-chloro-, and 3,5-dichlorobenzoate by a pseudomonadQ41664811
Degradation of mono-, di-, and trihalogenated benzoic acids by Pseudomonas aeruginosa JB2.Q41905428
Degradation of 1,2,4-trichloro- and 1,2,4,5-tetrachlorobenzene by pseudomonas strains.Q42078346
Purification of 3,5-Dichlorocatechol 1,2-Dioxygenase, a Nonheme Iron Dioxygenase and a Key Enzyme in the Biodegradation of a Herbicide, 2,4-Dichlorophenoxyacetic acid (2,4-D), from Pseudomonas cepacia CSV90Q42277997
The broad substrate chlorobenzene dioxygenase and cis-chlorobenzene dihydrodiol dehydrogenase of Pseudomonas sp. strain P51 are linked evolutionarily to the enzymes for benzene and toluene degradationQ42556559
Characterization of two alternative promoters for integrase expression in the clc genomic island of Pseudomonas sp. strain B13.Q42602177
Genetic organization of the catabolic plasmid pJP4 from Ralstonia eutropha JMP134 (pJP4) reveals mechanisms of adaptation to chloroaromatic pollutants and evolution of specialized chloroaromatic degradation pathwaysQ42628960
Chemical structure and biodegradability of halogenated aromatic compounds. Substituent effects on 1,2-dioxygenation of catecholQ42935823
The chlorocatechol degradative genes, tfdT-CDEF, of Burkholderia sp. strain NK8 are involved in chlorobenzoate degradation and induced by chlorobenzoates and chlorocatecholsQ43614720
4-Chlorocatechol 1,2-dioxygenase from the chlorophenol-utilizing Gram-positive Rhodococcus opacus 1CP: crystallization and preliminary crystallographic analysisQ44010736
Complete characterisation of Tn5530 from Burkholderia cepacia strain 2a (pIJB1) and studies of 2,4-dichlorophenoxyacetate uptake by the organismQ44121881
Preliminary crystallographic analysis of 3-chlorocatechol 1,2-dioxygenase of a new modified ortho-pathway from the Gram-positive Rhodococcus opacus 1CP grown on 2-chlorophenolQ44260581
P433issue15
P407language of work or nameEnglishQ1860
P921main subject3,4-dichlorocatecholQ27162853
2,3-dichloromuconate(2-)Q27162855
P304page(s)5427-5436
P577publication date2005-08-01
P1433published inJournal of BacteriologyQ478419
P1476titleAmino acids in positions 48, 52, and 73 differentiate the substrate specificities of the highly homologous chlorocatechol 1,2-dioxygenases CbnA and TcbC
P478volume187