Sequence features that drive human promoter function and tissue specificity

scientific article

Sequence features that drive human promoter function and tissue specificity is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1101/GR.100370.109
P932PMC publication ID2892090
P698PubMed publication ID20501695
P5875ResearchGate publication ID44629595

P2093author name stringZhiping Weng
Richard M Myers
Nathan D Trinklein
David S Johnson
Catherine Medina
Hennady Shulha
Jane M Landolin
Shelly F Aldred
P2860cites workTissue-specific regulatory elements in mammalian promotersQ38305745
Computational inference of transcriptional regulatory networks from expression profiling and transcription factor binding site identificationQ38346312
Distinct DNA methylation patterns characterize differentiated human embryonic stem cells and developing human fetal liverQ39875092
Eukaryotic transcription: an interlaced network of transcription factors and chromatin-modifying machinesQ41708885
Computational identification and functional validation of regulatory motifs in cartilage-expressed genes.Q41736027
DBTSS: database of transcription start sites, progress report 2008.Q43032565
Selection of DNA binding sites by regulatory proteins. Statistical-mechanical theory and application to operators and promoters.Q52603460
HNF4: A central regulator of hepatocyte differentiation and functionQ58407206
Fine structure genetic analysis of a beta-globin promoterQ68722751
Functional architecture and evolution of transcriptional elements that drive gene coexpressionQ81301649
Identification and analysis of functional elements in 1% of the human genome by the ENCODE pilot projectQ21061203
GENCODE: producing a reference annotation for ENCODEQ21184138
A genome-wide analysis of CpG dinucleotides in the human genome distinguishes two distinct classes of promotersQ24537436
TRANSFAC and its module TRANSCompel: transcriptional gene regulation in eukaryotesQ24538709
A gene atlas of the mouse and human protein-encoding transcriptomesQ24568043
Cap analysis gene expression for high-throughput analysis of transcriptional starting point and identification of promoter usageQ24616834
Systematic discovery of regulatory motifs in human promoters and 3' UTRs by comparison of several mammalsQ24630840
Analysis of overrepresented motifs in human core promoters reveals dual regulatory roles of YY1Q24673569
Integrative annotation of 21,037 human genes validated by full-length cDNA clonesQ24805388
Nonlinear partial differential equations and applications: Genomic analysis of the host response to hepatitis C virus infectionQ27473003
The transcriptional landscape of the mammalian genomeQ27861110
DNA binding sites: representation and discoveryQ28144459
Fusion transcripts and transcribed retrotransposed loci discovered through comprehensive transcriptome analysis using Paired-End diTags (PETs)Q28757561
Detection of functional DNA motifs via statistical over-representationQ28775981
Genome-wide mapping of in vivo protein-DNA interactionsQ29547162
A global map of p53 transcription-factor binding sites in the human genomeQ29614400
Information content of binding sites on nucleotide sequencesQ29614588
In vivo enhancer analysis of human conserved non-coding sequencesQ29616554
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genomeQ29616819
Recursive SVM feature selection and sample classification for mass-spectrometry and microarray dataQ31036404
De novo discovery of a tissue-specific gene regulatory module in a chordateQ34056053
Disruption of CREB function in brain leads to neurodegenerationQ34124865
Comprehensive analysis of transcriptional promoter structure and function in 1% of the human genomeQ34324178
Identification and functional analysis of human transcriptional promotersQ34374098
DNA motifs in human and mouse proximal promoters predict tissue-specific expressionQ34597423
Neuronal competition and selection during memory formation.Q34620892
Transcription factor binding and modified histones in human bidirectional promotersQ34637346
CREB, neurogenesis and depressionQ36944859
P433issue7
P304page(s)890-898
P577publication date2010-05-25
P1433published inGenome ResearchQ5533485
P1476titleSequence features that drive human promoter function and tissue specificity
P478volume20

Reverse relations

cites work (P2860)
Q93009109A comparison of curated gene sets versus transcriptomics-derived gene signatures for detecting pathway activation in immune cells
Q38771070A new computational method to predict transcriptional activity of a DNA sequence from diverse datasets of massively parallel reporter assays
Q21092716A user's guide to the encyclopedia of DNA elements (ENCODE)
Q41083733Baf60b-mediated ATM-p53 activation blocks cell identity conversion by sensing chromatin opening
Q57172050CRX directs photoreceptor differentiation by accelerating chromatin remodeling at specific target sites
Q38959992Cancer specificity of promoters of the genes controlling cell proliferation.
Q45885614Cancer-specific promoters for expression-targeted gene therapy: ran, brms1 and mcm5.
Q22122000Comparative studies of gene expression and the evolution of gene regulation
Q55515822Consistent inverse correlation between DNA methylation of the first intron and gene expression across tissues and species.
Q28315762CpG islands and the regulation of transcription
Q34826504DNA methylation of alternative promoters directs tissue specific expression of Epac2 isoforms
Q42917897Decoding a signature-based model of transcription cofactor recruitment dictated by cardinal cis-regulatory elements in proximal promoter regions.
Q90663956Determinants of enhancer and promoter activities of regulatory elements
Q36012656Diametrically opposite methylome-transcriptome relationships in high- and low-CpG promoter genes in postmitotic neural rat tissue.
Q35120737Discovery of SMAD4 promoters, transcription factor binding sites and deletions in juvenile polyposis patients
Q39588955Effects of DNA methylation and histone modification on differentiation-associated gene expression in ES, NIH3T3, and NIT-1.
Q38171275Epigenetic landscape for initiation of DNA replication
Q37970038Epigenetic regulation of self-renewal and fate determination in neural stem cells
Q38750145Expression of metastasis suppressor gene AES driven by a Yin Yang (YY) element in a CpG island promoter and transcription factor YY2.
Q35128053FIREWACh: high-throughput functional detection of transcriptional regulatory modules in mammalian cells
Q36378033Functional analysis of transcription factor binding sites in human promoters
Q56985332Functional conservation of sequence determinants at rapidly evolving regulatory regions across mammals
Q34000374Fundamental diversity of human CpG islands at multiple biological levels
Q37504912Genome-wide analysis of promoters: clustering by alignment and analysis of regular patterns
Q36233375Genome-wide mapping of autonomous promoter activity in human cells
Q36084287Genomic approaches for understanding the genetics of complex disease
Q38019305Genomic approaches towards finding cis-regulatory modules in animals
Q38264460HMGA proteins as modulators of chromatin structure during transcriptional activation.
Q34729636High resolution mapping of Twist to DNA in Drosophila embryos: Efficient functional analysis and evolutionary conservation
Q37148610High-throughput functional comparison of promoter and enhancer activities
Q34350068High-throughput functional testing of ENCODE segmentation predictions.
Q34130817Human Vav1 expression in hematopoietic and cancer cell lines is regulated by c-Myb and by CpG methylation
Q47203571Local sequence features that influence AP-1 cis-regulatory activity
Q33764215MOF-associated complexes ensure stem cell identity and Xist repression.
Q34354921Massively parallel in vivo enhancer assay reveals that highly local features determine the cis-regulatory function of ChIP-seq peaks.
Q36127883Ovine HSP90AA1 gene promoter: functional study and epigenetic modifications.
Q39283934Predicting cell-type-specific gene expression from regions of open chromatin
Q42137507Predicting promoter activities of primary human DNA sequences
Q36101103Proline oxidase promotes tumor cell survival in hypoxic tumor microenvironments
Q34107760Relating gene expression evolution with CpG content changes
Q48257532Relationship between histone modifications and transcription factor binding is protein family specific
Q57274692Response to Comment on "Positive Selection of Tyrosine Loss in Metazoan Evolution"
Q52936646SMAD4 gene promoter mutations in patients with thyroid tumors.
Q37697916Sequence signatures extracted from proximal promoters can be used to predict distal enhancers
Q40258257Species differential regulation of COX2 can be described by an NFκB-dependent logic AND gate
Q37658966Systematic dissection of genomic features determining transcription factor binding and enhancer function
Q89982549The Gossypium longicalyx Genome as a Resource for Cotton Breeding and Evolution
Q34193554The influence of cis-regulatory elements on DNA methylation fidelity
Q30562517Understanding transcriptional regulation by integrative analysis of transcription factor binding data.
Q33631937Use of phage display to identify novel mineralocorticoid receptor-interacting proteins.
Q50074557ZFX acts as a transcriptional activator in multiple types of human tumors by binding downstream of transcription start sites at the majority of CpG island promoters.

Search more.