Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: the randomized PILLAR study

scientific article

Once-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: the randomized PILLAR study is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/HEP.26641
P932PMC publication ID4112500
P698PubMed publication ID23907700
P5875ResearchGate publication ID254272552

P50authorIgor NikitinQ56980284
Robert FlisiakQ56980311
Patrick MarcellinQ89798262
Gregory J DoreQ90411646
Maria ButiQ91265862
Stefan ZeuzemQ28360321
Maria Beumont-MauvielQ47158921
Fred PoordadQ47412568
P2093author name stringOliver Lenz
Maria Beumont-Mauviel
Monika Peeters
Michael Manns
Peter Ferenci
Goedele De Smedt
Ira Jacobson
Jane Scott
Leen Gilles
Michael W Fried
Morris Sherman
Vanitha Sekar
P2860cites workPsychometric evaluation of the fatigue severity scale for use in chronic hepatitis CQ73467050
A SPECIAL MEETING REVIEW EDITION: Updates in the Treatment of Hepatitis C Virus Infection From EASL 2012: The 47th Annual Meeting of the European Association for the Study of the LiverApril 18-22, 2012 • Barcelona, SpainSpecial Reporting on:• SafetyQ93603855
An update on treatment of genotype 1 chronic hepatitis C virus infection: 2011 practice guideline by the American Association for the Study of Liver DiseasesQ24632766
In vitro activity and preclinical profile of TMC435350, a potent hepatitis C virus protease inhibitorQ24650264
Maximizing opportunities and avoiding mistakes in triple therapy for hepatitis C virusQ26830190
Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearanceQ28255243
Genetic variation in IL28B is associated with chronic hepatitis C and treatment failure: a genome-wide association studyQ28269827
Interleukin-28B polymorphism improves viral kinetics and is the strongest pretreatment predictor of sustained virologic response in genotype 1 hepatitis C virusQ28279955
IL28B is associated with response to chronic hepatitis C interferon-alpha and ribavirin therapyQ29614896
Genome-wide association of IL28B with response to pegylated interferon-alpha and ribavirin therapy for chronic hepatitis CQ29619541
Diagnosis, management, and treatment of hepatitis C: an updateQ29619682
Telaprevir for previously untreated chronic hepatitis C virus infectionQ29619800
Boceprevir for untreated chronic HCV genotype 1 infectionQ29620617
Response-guided telaprevir combination treatment for hepatitis C virus infectionQ34632295
Host genomics and HCV treatment response.Q37932036
Direct acting antivirals for the treatment of chronic hepatitis C: one pill a day for tomorrowQ37972768
In vitro resistance profile of the hepatitis C virus NS3/4A protease inhibitor TMC435.Q39736457
Antiviral activity of TMC435 monotherapy in patients infected with HCV genotypes 2-6: TMC435-C202, a phase IIa, open-label studyQ42977630
Rapid HCV-RNA decline with once daily TMC435: a phase I study in healthy volunteers and hepatitis C patientsQ42992022
Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a phase Ib, placebo-controlled, randomized studyQ43032179
SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon alpha-2b for genotype 1 nonrespondersQ43036959
Rapid viral response of once-daily TMC435 plus pegylated interferon/ribavirin in hepatitis C genotype-1 patients: a randomized trialQ43041743
Vaniprevir with pegylated interferon alpha-2a and ribavirin in treatment-naïve patients with chronic hepatitis C: a randomized phase II studyQ47243589
P433issue6
P407language of work or nameEnglishQ1860
P921main subjecthepatitis CQ154869
ribavirinQ421862
pegylated interferonQ7160835
simeprevirQ7517689
P304page(s)1918-1929
P577publication date2013-10-11
P1433published inHepatologyQ15724398
P1476titleOnce-daily simeprevir (TMC435) with pegylated interferon and ribavirin in treatment-naïve genotype 1 hepatitis C: the randomized PILLAR study
P478volume58

Reverse relations

cites work (P2860)
Q47548210A 3-year follow-up study after treatment with simeprevir in combination with pegylated interferon-α and ribavirin for chronic hepatitis C virus infection.
Q40888934A Phase I Dose Escalation Study Demonstrates Quercetin Safety and Explores Potential for Bioflavonoid Antivirals in Patients with Chronic Hepatitis C.
Q40784150A non-human hepadnaviral adjuvant for hepatitis C virus-based genetic vaccines
Q38221090Antiviral therapy for chronic hepatitis C in 2014.
Q26851810Antiviral treatment of hepatitis C virus infection and factors affecting efficacy
Q42207125Antiviral treatment of hepatitis C.
Q38244931Asunaprevir-containing regimens for the treatment of hepatitis C virus infection.
Q38204368Benefit-risk assessment of new and emerging treatments for hepatitis C: focus on simeprevir and sofosbuvir
Q34725990Beyond interferon: rationale and prospects for newer treatment paradigms for chronic hepatitis C.
Q35854698Burden of hepatitis C virus disease and access to hepatitis C virus services in people who inject drugs in India: a cross-sectional study
Q34775524CIHR Canadian HIV Trials Network Co-Infection and Concurrent Diseases Core: Updated Canadian guidelines for the treatment of hepatitis C infection in HIV-hepatitis C coinfected adults
Q38217932CROI 2014: Viral hepatitis and complications of HIV disease and antiretroviral therapy
Q38230357Cell and tissue engineering for liver disease
Q38403350Changes in the Prevalence of Hepatitis C Virus Infection, Nonalcoholic Steatohepatitis, and Alcoholic Liver Disease Among Patients With Cirrhosis or Liver Failure on the Waitlist for Liver Transplantation
Q91599703Changing Treatment Landscape of Hepatitis C Virus Infection Among Penitentiary Inmates
Q38838703Chronic hepatitis C burden and care cascade in Australia in the era of interferon-based treatment
Q37654449Chronic hepatitis C genotype 1 virus: who should wait for treatment?
Q26775011Chronic hepatitis C: This and the new era of treatment
Q28541762Comparative molecular dynamics simulation of Hepatitis C Virus NS3/4A protease (Genotypes 1b, 3a and 4b) predicts conformational instability of the catalytic triad in drug resistant strains
Q46661989Comparison of first- and second-wave DAAs for HCV GT1: efficacy, safety, tolerability, and regimen complexity
Q42175896Control of HCV Replication With iMIRs, a Novel Anti-RNAi Agent
Q39153261Cost-effectiveness analysis of sofosbuvir plus peginterferon/ribavirin in the treatment of chronic hepatitis C virus genotype 1 infection
Q38206573Cost-effectiveness of protease inhibitor based regimens for chronic hepatitis C: a systematic review of published literature
Q38208508Current status in the therapy of liver diseases
Q39151677Current therapy for chronic hepatitis C: The role of direct-acting antivirals
Q59360673Daclatasvir and asunaprevir combination therapy for patients with chronic hepatitis C virus genotype 1b infection in real world
Q35154587Deconvoluting the composition of low-frequency hepatitis C viral quasispecies: comparison of genotypes and NS3 resistance-associated variants between HCV/HIV coinfected hemophiliacs and HCV monoinfected patients in Japan.
Q36327795Determinant Factors of the Direct Medical Costs Associated with Genotype 1 Hepatitis C Infection in Treatment-Experienced Patients
Q38515906Development of antiviral drugs for the treatment of hepatitis C at an accelerating pace
Q35905985Direct-acting Antiviral Agents for the Treatment of Chronic Hepatitis C Virus Infection
Q35473208Direct-acting antiviral-based triple therapy on alpha-fetoprotein level in chronic hepatitis C patients
Q57389418Direct-acting antivirals for chronic hepatitis C
Q34557595Direct-acting antivirals for chronic hepatitis C.
Q40642039Distribution of IL28B Polymorphism in a Cohort of Italians and Immigrants with HCV Infection: Association with Viraemia, Stage of Fibrosis and Response to Treatment.
Q39010715Do disparities between populations in randomized controlled trials and the real world lead to differences in outcomes?
Q28084266Drug-Drug Interactions with the NS3/4A Protease Inhibitor Simeprevir
Q36668891Drug-drug interactions with oral anti-HCV agents and idiosyncratic hepatotoxicity in the liver transplant setting
Q38909432Effect of Chronic Hepatitis C Virus Treatment by Combination Therapy on Cardiovascular System
Q95812891Effect of Treatment with Direct Acting Antiviral on Glycemic Control in Patients with Diabetes Mellitus and Chronic Hepatitis C
Q41469651Effect of native vitamin D3 supplementation on refractory chronic hepatitis C patients in simeprevir with pegylated interferon/ribavirin
Q41160646Effectiveness of triple therapy with simeprevir for chronic hepatitis C genotype 1b patients with prior telaprevir failure
Q28074783Efficacy and Safety of Ribavirin with Sofosbuvir Plus Ledipasvir in Patients with Genotype 1 Hepatitis C: A Meta-Analysis
Q37651899Efficacy and safety of telaprevir- and simeprevir-based triple therapies for older patients with chronic hepatitis C
Q64104306Efficacy of L-carnitine on ribavirin-induced hemolytic anemia in patients with hepatitis C virus infection
Q26771458Efficacy of Second Generation Direct-Acting Antiviral Agents for Treatment Naïve Hepatitis C Genotype 1: A Systematic Review and Network Meta-Analysis
Q40291443Efficacy, safety, and pharmacokinetics of simeprevir, daclatasvir, and ribavirin in patients with recurrent hepatitis C virus genotype 1b infection after orthotopic liver transplantation: The Phase II SATURN study
Q26853642Emerging therapies for hepatitis C
Q35031753Estimating the clinical and economic benefit associated with incremental improvements in sustained virologic response in chronic hepatitis C
Q36148043Evaluation of Resistance-Associated Substitutions in NS5A Using Direct Sequence and Cycleave Method and Treatment Outcome with Daclatasvir and Asunaprevir for Chronic Hepatitis C Genotype 1.
Q41473188Evolution of simeprevir-resistant variants in virological non-responders infected with HCV genotype 1b.
Q42220429Evolution of simeprevir-resistant variants over time by ultra-deep sequencing in HCV genotype 1b.
Q34174207Fatigue during treatment for hepatitis C virus: results of self-reported fatigue severity in two Phase IIb studies of simeprevir treatment in patients with hepatitis C virus genotype 1 infection
Q33424681Favorable adverse event profile of sofosbuvir/ribavirin compared to boceprevir/interferon/ribavirin for treatment of hepatitis C.
Q35164782First-generation protease inhibitor-triple therapy: SVR 24, safety, and predictors of response in a large single center cohort
Q28552269Geno2pheno[HCV] - A Web-based Interpretation System to Support Hepatitis C Treatment Decisions in the Era of Direct-Acting Antiviral Agents
Q40356056Glecaprevir and pibrentasvir for 12 weeks for hepatitis C virus genotype 1 infection and prior direct-acting antiviral treatment
Q41666553Global origin and transmission of hepatitis C virus nonstructural protein 3 Q80K polymorphism
Q40557598Grazoprevir plus peginterferon and ribavirin in treatment-naive patients with hepatitis C virus genotype 1 infection: a randomized trial
Q57168365HCV NS3/4A Protease Inhibitors and the Road to Effective Direct-Acting Antiviral Therapies
Q30301355Hepatic decompensation likely attributable to simeprevir in patients with advanced cirrhosis.
Q39305112Hepatitis B and C.
Q28084654Hepatitis C
Q26781984Hepatitis C Recurrence after Orthotopic Liver Transplantation: Mechanisms and Management
Q34298877Hepatitis C Virus (HCV) NS3 sequence diversity and antiviral resistance-associated variant frequency in HCV/HIV coinfection
Q34181683Hepatitis C Virus in Pregnancy and Early Childhood: Current Understanding and Knowledge Deficits
Q34439125Hepatitis C drugs: the end of the pegylated interferon era and the emergence of all-oral interferon-free antiviral regimens: a concise review
Q26775815Hepatitis C genotype 4: The past, present, and future
Q41758808Hepatitis C in African Americans
Q30378509Hepatitis C treatment: where are we now?
Q34111759Hepatitis C virus NS3 mutations in haemophiliacs
Q26782033Hepatitis C virus markers in infection by hepatitis C virus: In the era of directly acting antivirals
Q24628717Hepatitis C virus protease inhibitor-resistance mutations: our experience and review
Q27468916Hepatitis C virus: Promising discoveries and new treatments
Q42250363Hepatocarcinogenesis in chronic hepatitis C patients achieving a sustained virological response to interferon: significance of lifelong periodic cancer screening for improving outcomes
Q40827559IFNL4 polymorphism effects on outcome of simeprevir, peginterferon, and ribavirin therapy for older patients with genotype 1 chronic hepatitis C.
Q97519947Identification of potential inhibitors against SARS-CoV-2 by targeting proteins responsible for envelope formation and virion assembly using docking based virtual screening, and pharmacokinetics approaches
Q35501259Impact of all oral anti-hepatitis C virus therapy: A meta-analysis
Q40988716In Vitro Activity of Simeprevir against Hepatitis C Virus Genotype 1 Clinical Isolates and Its Correlation with NS3 Sequence and Site-Directed Mutants.
Q33717146Increase of Soluble Programmed Cell Death Ligand 1 in Patients with Chronic Hepatitis C.
Q59354172Interferon at the cellular, individual, and population level in hepatitis C virus infection: Its role in the interferon-free treatment era
Q43100552Interferon-based combination treatment for chronic hepatitis C in the era of direct acting antivirals
Q42249679Interferon-α/β for treatment of chronic hepatitis C infection in the era of direct-acting antiviral agents.
Q91262277JNJ-4178 (AL-335, Odalasvir, and Simeprevir) for 6 or 8 Weeks in Hepatitis C Virus-Infected Patients Without Cirrhosis: OMEGA-1
Q42244738JSH Guidelines for the Management of Hepatitis C Virus Infection: A 2014 Update for Genotype 1.
Q41429836Ledipasvir-sofosbuvir with or without ribavirin to treat patients with HCV genotype 1 infection and cirrhosis non-responsive to previous protease-inhibitor therapy: a randomised, double-blind, phase 2 trial (SIRIUS).
Q40217467Long-Term Follow-Up of Resistance-Associated Substitutions in Hepatitis C Virus in Patients in Which Direct Acting Antiviral-Based Therapy Failed
Q33390630Long-term functional duration of immune responses to HCV NS3/4A induced by DNA vaccination
Q38584289Management of Hepatitis C Before and After Liver Transplantation in the Era of Rapidly Evolving Therapeutic Advances
Q34143327Medication use and medical comorbidity in patients with chronic hepatitis C from a US commercial claims database: high utilization of drugs with interaction potential.
Q36901167Multicentric performance analysis of HCV quantification assays and its potential relevance for HCV treatment
Q38215505NS3 protease inhibitors for treatment of chronic hepatitis C: Efficacy and safety.
Q33559298Nanomedicines in the treatment of hepatitis C virus infection in Asian patients: optimizing use of peginterferon alfa
Q90086733New Direct-Acting Antivirals for the Treatment of Patients With Hepatitis C Virus Infection: A Systematic Review of Randomized Controlled Trials
Q33560181New Therapies for Hepatitis C Virus Infection
Q50283732New direct-acting antiviral agents for the treatment of chronic hepatitis C in 2014
Q26800050New era for management of chronic hepatitis C virus using direct antiviral agents: A review
Q45328037New hepatitis C antiviral treatments eliminate the virus
Q26795407New treatment strategies for hepatitis C infection
Q26853138New treatments for genotype 1 chronic hepatitis C - focus on simeprevir
Q45846064Once-daily simeprevir in combination with pegylated-interferon and ribavirin: a new horizon in the era of direct-acting antiviral agent therapy for chronic hepatitis C.
Q42231673Once-daily simeprevir with peginterferon and ribavirin for treatment-experienced HCV genotype 1-infected patients in Japan: the CONCERTO-2 and CONCERTO-3 studies
Q38249065Optimizing triple therapy and IFN/RBV-free regimens for hepatitis C virus infection
Q30418176PNPLA3 I148M associations with liver carcinogenesis in Japanese chronic hepatitis C patients
Q30300424Persistence of mixed cryoglobulinemia despite cure of hepatitis C with new oral antiviral therapy including direct-acting antiviral sofosbuvir: A case series.
Q30365599Pharmacogenetics of hepatitis C: transition from interferon-based therapies to direct-acting antiviral agents
Q38995225Polymorphisms at IL28B gene as predictors of viral relapse in genotype 4 Egyptian hepatitis C patients.
Q40671964Pre-existence and Persistence of Resistant Minority Hepatitis C Virus Variants in Genotype 1-Infected Patients Treated With Simeprevir/Peginterferon/Ribavirin.
Q35370579Predictability of IL-28B-polymorphism on protease-inhibitor-based triple-therapy in chronic HCV-genotype-1 patients: A meta-analysis
Q30374727Prediction of the Risk of Hepatocellular Carcinoma in Chronic Hepatitis C Patients after Sustained Virological Response by Aspartate Aminotransferase to Platelet Ratio Index.
Q40533002Protease Inhibitor Resistance Remains Even After Mutant Strains Become Undetectable by Deep Sequencing
Q26798477Psychiatric and substance use disorders co-morbidities and hepatitis C: Diagnostic and treatment implications
Q40771120Randomized trial of combined triple therapy comprising two types of peginterferon with simeprevir in patients with hepatitis C virus genotype 1b.
Q36100521Re-treatment of chronic hepatitis C virus genotype 1 infection after relapse: an open-label pilot study
Q39398874Real-World Single-Center Experience with Sofosbuvir-Based Regimens for the Treatment of Chronic Hepatitis C Genotype 1 Patients
Q53836297Recommendations on hepatitis C screening for adults.
Q38213847Response-guided therapy in patients with genotype 1 hepatitis C virus: current status and future prospects
Q38206215Review article: 2014 UK consensus guidelines - hepatitis C management and direct-acting anti-viral therapy.
Q38703524Review article: safety and tolerability of direct-acting anti-viral agents in the new era of hepatitis C therapy
Q36874995Risk factors for deterioration of long-term liver function after radiofrequency ablation therapy
Q38170161Role of IL28B for chronic hepatitis C treatment toward personalized medicine
Q41077060SILEN-C3, a phase 2 randomized trial with faldaprevir plus pegylated interferon α-2a and ribavirin in treatment-naive hepatitis C virus genotype 1-infected patients
Q40539146Safety and efficacy of dual therapy with daclatasvir and asunaprevir for older patients with chronic hepatitis C.
Q41104105Severe liver injury associated with simeprevir plus pegylated interferon/ribavirin therapy in a patient with treatment-naïve genotype 1b hepatitis C virus: a case report
Q59355494Short-Duration AL-335, Odalasvir, With or Without Simeprevir, in Patients With HCV GT1 or 3 Infection Without Cirrhosis
Q38899447Significance of HCV RNA monitoring in the era of new potent therapies
Q42210312Simeprevir (TMC435) once daily with peginterferon-α-2b and ribavirin in patients with genotype 1 hepatitis C virus infection: The CONCERTO-4 study
Q41752261Simeprevir (TMC435) with pegylated interferon/ribavirin in patients coinfected with HCV genotype 1 and HIV-1: a phase 3 study
Q41610311Simeprevir added to peginterferon and ribavirin lessens time with fatigue, depressive symptoms and functional limitations in patients with chronic hepatitis C compared with peginterferon and ribavirin: results from 1161 patients in the QUEST-1, QUES
Q40035445Simeprevir and Sofosbuvir (SMV-SOF) for 12 Weeks for the Treatment of Chronic Hepatitis C Genotype 1 Infection: A Real World (Transplant) Hepatology Practice Experience
Q39968319Simeprevir and sofosbuvir with or without ribavirin to treat recurrent genotype 1 hepatitis C virus infection after orthotopic liver transplantation
Q33774821Simeprevir capsules
Q38216582Simeprevir for the treatment of chronic hepatitis C genotype 1 infection
Q38248210Simeprevir for the treatment of hepatitis C and HIV/hepatitis C co-infection
Q38247985Simeprevir for the treatment of hepatitis C virus infection
Q41613250Simeprevir versus telaprevir with peginterferon and ribavirin in previous null or partial responders with chronic hepatitis C virus genotype 1 infection (ATTAIN): a randomised, double-blind, non-inferiority phase 3 trial
Q36391682Simeprevir with peginterferon α-2a/ribavirin for chronic hepatitis C virus genotype 1 infection in treatment-experienced patients: an open-label, rollover study
Q36834349Simeprevir with peginterferon/ribavirin for patients with hepatitis C virus genotype 1: high frequency of viral relapse in elderly patients
Q41680620Simeprevir with peginterferon/ribavirin for treatment of chronic hepatitis C virus genotype 1 infection: pooled safety analysis from Phase IIb and III studies
Q42211652Simeprevir with pegylated interferon alfa 2a or 2b plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-2): a randomised, double-blind, placebo-controlled phase 3 trial
Q42211649Simeprevir with pegylated interferon alfa 2a plus ribavirin in treatment-naive patients with chronic hepatitis C virus genotype 1 infection (QUEST-1): a phase 3, randomised, double-blind, placebo-controlled trial
Q33853210Simeprevir-Based Triple Therapy with Reduced Doses of Pegylated Interferon α-2a Plus Ribavirin for Interferon Ineligible Patients with Genotype 1b Hepatitis C Virus
Q40923578Simeprevir/pegylated interferon/ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation
Q38307580Simeprevir: a review of its use in patients with chronic hepatitis C virus infection
Q38167686Simeprevir: first global approval
Q38219424Sofosbuvir (Sovaldi) for the treatment of hepatitis C.
Q26770024Sofosbuvir treatment and hepatitis C virus infection
Q35037688Sofosbuvir-based treatment regimens for chronic, genotype 1 hepatitis C virus infection in U.S. incarcerated populations: a cost-effectiveness analysis
Q38849917Structure-activity relationship studies on quinoxalin-2(1H)-one derivatives containing thiazol-2-amine against hepatitis C virus leading to the discovery of BH6870.
Q35903139Sustained Virological Response after 8-Week Treatment of Simeprevir with Peginterferon α-2a plus Ribavirin in a Japanese Female with Hepatitis C Virus Genotype 1b and IL28B Minor Genotype
Q39483711Sustained virologic response by direct antiviral agents reduces the incidence of hepatocellular carcinoma in patients with HCV infection.
Q26768128Systematic Review and Network Meta-Analysis of Randomized Controlled Trials: Comparative Effectiveness and Safety of Direct-Acting Antiviral Agents for Treatment-Naive Hepatitis C Genotype 1
Q38816811Targeting IFN-λ: therapeutic implications
Q36218266The NS4A Cofactor Dependent Enhancement of HCV NS3 Protease Activity Correlates with a 4D Geometrical Measure of the Catalytic Triad Region
Q40340001The efficacy and safety of dual oral therapy with daclatasvir and asunaprevir for genotype 1b in Japanese real-life settings
Q39075044The future disease burden of hepatitis C virus infection in Sweden and the impact of different treatment strategies
Q42220068The prospective randomized study on telaprevir at 1500 or 2250 mg with pegylated interferon plus ribavirin in Japanese patients with HCV genotype 1.
Q38668968The role of HCV proteins on treatment outcomes
Q38197441The role of chemokines in hepatitis C virus-mediated liver disease
Q38206556The role of interferon in the new era of hepatitis C treatments
Q38174250Treating HCV in HIV 2013: on the cusp of change
Q38352572Treatment of chronic hepatitis C in patients with HIV/HCV coinfection
Q35880497Two Distinct Hepatitis C Virus Genotype 1a Clades Have Different Geographical Distribution and Association With Natural Resistance to NS3 Protease Inhibitors
Q41043113Two patients treated with simeprevir plus pegylated-interferon and ribavirin triple therapy for recurrent hepatitis C after living donor liver transplantation: case report
Q38263444Understanding the potential of hepatitis C virus internal ribosome entry site domains to modulate translation initiation via their structure and function.
Q45325544Usefulness of semiquantitative PCR-Invader assay for selecting candidates for daclatasvir plus asunaprevir combination therapy among patients with hepatitis C virus genotype 1b.
Q33890671Validation of the Fatigue Severity Scale in chronic hepatitis C.
Q42181383Variation analysis of six HCV viral load assays using low viremic HCV samples in the range of the clinical decision points for HCV protease inhibitors
Q35592257Virological response after 6 week triple-drug regimens for hepatitis C: a proof-of-concept phase 2A cohort study
Q38751552Virology analysis in HCV genotype 1-infected patients treated with the combination of simeprevir and TMC647055/ritonavir, with and without ribavirin, and JNJ-56914845.

Search more.