Studying genomes through the aeons: protein families, pseudogenes and proteome evolution

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Studying genomes through the aeons: protein families, pseudogenes and proteome evolution is …
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scholarly articleQ13442814
review articleQ7318358

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P356DOI10.1016/S0022-2836(02)00109-2
P698PubMed publication ID12083509

P50authorMark Bender GersteinQ6766711
P2093author name stringPaul M Harrison
P2860cites workInitial sequencing and analysis of the human genomeQ21045365
Molecular fossils in the human genome: identification and analysis of the pseudogenes in chromosomes 21 and 22Q22065758
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SNPs on human chromosomes 21 and 22 -- analysis in terms of protein features and pseudogenesQ74251808
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Protein family and fold occurrence in genomes: power-law behaviour and evolutionary modelQ77135232
Pseudogene evolution and natural selection for a compact genomeQ22066034
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Massive gene decay in the leprosy bacillusQ22122381
Genome sequence of enterohaemorrhagic Escherichia coli O157:H7Q22122385
Analysis of the genome sequence of the flowering plant Arabidopsis thalianaQ22122387
The genome sequence of Rickettsia prowazekii and the origin of mitochondriaQ22122428
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Gapped BLAST and PSI-BLAST: a new generation of protein database search programsQ24545170
Lineage-specific loss and divergence of functionally linked genes in eukaryotesQ24675220
The human olfactory receptor repertoireQ24800049
Genome sequence of the nematode C. elegans: a platform for investigating biologyQ27860527
The complete genome sequence of Escherichia coli K-12Q27860542
SCOP: a structural classification of proteins database for the investigation of sequences and structuresQ27860689
The genome sequence of Drosophila melanogasterQ27860796
Functional characterization of the S. cerevisiae genome by gene deletion and parallel analysisQ27860815
Life with 6000 genesQ27860877
The evolutionary fate and consequences of duplicate genesQ27861065
The DNA sequence of human chromosome 22Q28139873
A yeast prion provides a mechanism for genetic variation and phenotypic diversityQ28140932
InterPro--an integrated documentation resource for protein families, domains and functional sitesQ28142845
The DNA sequence of human chromosome 21Q28145358
Homology-based annotation yields 1,042 new candidate genes in the Drosophila melanogaster genomeQ28204301
Nature and structure of human genes that generate retropseudogenesQ35026861
How malleable is the eukaryotic genome? Extreme rate of chromosomal rearrangement in the genus DrosophilaQ35031608
Gene duplication and the structure of eukaryotic genomesQ35031751
Marginal fitness contributions of nonessential genes in yeastQ35674564
Highly specific protein sequence motifs for genome analysisQ36252448
Digging for dead genes: an analysis of the characteristics of the pseudogene population in the Caenorhabditis elegans genomeQ38668496
A question of size: the eukaryotic proteome and the problems in defining it.Q39535215
The SYSTERS protein sequence cluster set.Q39541174
ProtoMap: automatic classification of protein sequences and hierarchy of protein familiesQ39541528
Whole-genome trees based on the occurrence of folds and orthologs: implications for comparing genomes on different levelsQ40414224
Classification of transmembrane protein families in the Caenorhabditis elegans genome and identification of human orthologsQ40414478
Frequent alternative splicing of human genesQ40414677
Computational inference of homologous gene structures in the human genomeQ40414965
Translation termination efficiency can be regulated in Saccharomyces cerevisiae by environmental stress through a prion-mediated mechanismQ41874945
Pseudogenes, junk DNA, and the dynamics of Rickettsia genomesQ42648137
Genome analysis: Assigning protein coding regions to three-dimensional structuresQ42847014
Protein dispensability and rate of evolutionQ46183570
Neurobiology of the Caenorhabditis elegans genome.Q46229602
Evolution of genome size: new approaches to an old problemQ47220744
Using the CATH domain database to assign structures and functions to the genome sequencesQ47621006
Primate evolution of an olfactory receptor cluster: diversification by gene conversion and recent emergence of pseudogenesQ47923362
High intrinsic rate of DNA loss in DrosophilaQ48057637
The gene family encoding the mouse ribosomal protein L32 contains a uniquely expressed intron-containing gene and an unmutated processed geneQ48390212
Gene index analysis of the human genome estimates approximately 120,000 genes.Q52077979
Robustness against mutations in genetic networks of yeast.Q52169621
The frequency distribution of gene family sizes in complete genomes.Q52243763
The evolution of an alpha-esterase pseudogene inactivated in the Drosophila melanogaster lineage.Q52577664
Structural genomics analysis: characteristics of atypical, common, and horizontally transferred folds.Q52938509
EST comparison indicates 38% of human mRNAs contain possible alternative splice forms.Q52971558
A small reservoir of disabled ORFs in the yeast genome and its implications for the dynamics of proteome evolution.Q53878162
The origins of genomic duplications in Arabidopsis.Q53900352
Analysis of Protein Domain Families inCaenorhabditis elegansQ56878447
Updated map of duplicated regions in the yeast genomeQ57252802
Genomic Exploration of the Hemiascomycetous Yeasts: 20. Evolution of gene redundancy compared to Saccharomyces cerevisiaeQ57984478
SUPERFAMILY: HMMs representing all proteins of known structure. SCOP sequence searches, alignments and genome assignmentsQ28212954
A structural census of the current population of protein sequencesQ28252365
Characterization of the yeast transcriptomeQ28302110
Molecular evidence for an ancient duplication of the entire yeast genomeQ29547472
Comparative genomics of the eukaryotesQ29547504
SGD: Saccharomyces Genome DatabaseQ29615402
Mechanisms of evolution in Rickettsia conorii and R. prowazekiiQ29615837
The complete human olfactory subgenomeQ29618326
Human LINE retrotransposons generate processed pseudogenesQ29618327
Vertebrate pseudogenesQ29618328
Processed pseudogenes: characteristics and evolutionQ29618329
Analysis of the yeast transcriptome with structural and functional categories: characterizing highly expressed proteinsQ30326247
A structural census of genomes: comparing bacterial, eukaryotic, and archaeal genomes in terms of protein structureQ30429158
Estimating the number of protein folds and families from complete genome dataQ30597194
Towards a truly integrative biology through the functional genomics of yeastQ30978871
How representative are the known structures of the proteins in a complete genome? A comprehensive structural censusQ31934081
MIPS: a database for genomes and protein sequencesQ33612236
Yeast genome evolution in the post-genome era.Q33745262
The minimal genome conceptQ33801555
Protein-only inheritance in yeast: something to get [PSI+]-ched aboutQ33838279
Yeast prions and their prion-forming domainQ33838897
The large srh family of chemoreceptor genes in Caenorhabditis nematodes reveals processes of genome evolution involving large duplications and deletions and intron gains and lossesQ33889888
Comprehensive analysis of amino acid and nucleotide composition in eukaryotic genomes, comparing genes and pseudogenesQ33891354
Analysis of expressed sequence tags indicates 35,000 human genesQ33903985
Estimate of human gene number provided by genome-wide analysis using Tetraodon nigroviridis DNA sequenceQ33903990
Updating the str and srj (stl) families of chemoreceptors in Caenorhabditis nematodes reveals frequent gene movement within and between chromosomesQ33936879
Intraspecies variation in bacterial genomes: the need for a species genome conceptQ34034113
A genetic uncertainty problemQ34080513
Horizontal gene transfer among microbial genomes: new insights from complete genome analysisQ34087782
mRNA quality control: Marking the message for life or death.Q34169710
Microbial genomes: dealing with diversityQ34265067
Evolution of immunoglobulin VH pseudogenes in chickensQ34320057
Pseudogenes in ribonuclease evolution: a source of new biomacromolecular function?Q34375847
Two large families of chemoreceptor genes in the nematodes Caenorhabditis elegans and Caenorhabditis briggsae reveal extensive gene duplication, diversification, movement, and intron lossQ34467653
Genes and proteins of Escherichia coli (GenProtEc)Q34586497
Comparison of the complete protein sets of worm and yeast: orthology and divergenceQ34670114
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectprotein evolutionQ59870539
P304page(s)1155-1174
P577publication date2002-05-01
P1433published inJournal of Molecular BiologyQ925779
P1476titleStudying genomes through the aeons: protein families, pseudogenes and proteome evolution
P478volume318

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