Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells.

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Proteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells. is …
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scholarly articleQ13442814

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P356DOI10.1002/PMIC.201100092
P8608Fatcat IDrelease_r3wohgomrfc2zie2u5xv3lpzly
P698PubMed publication ID21761561
P5875ResearchGate publication ID230255473

P50authorElena Di GennaroQ57061563
Alessandra LeoneQ57629449
Francesca BruzzeseQ63737239
Assunta GagliardiQ84205148
Laura BianchiQ38640243
Luca BiniQ38640254
Alfredo BudillonQ40122753
P2093author name stringBiagio Pucci
Alessandro Armini
Monia Rocco
Michele Puglia
Anna Gimigliano
P2860cites workEnhancing the antitumor activity of ErbB blockade with histone deacetylase (HDAC) inhibitionQ53657859
Ebp1 isoforms distinctively regulate cell survival and differentiationQ24296796
Endoplasmic reticulum chaperone protein GRP78 protects cells from apoptosis induced by topoisomerase inhibitors: role of ATP binding site in suppression of caspase-7 activationQ24298757
HDAC6 is a specific deacetylase of peroxiredoxins and is involved in redox regulationQ24310722
Human BRE1 is an E3 ubiquitin ligase for Ebp1 tumor suppressorQ24318682
Mitochondrial manganese-superoxide dismutase expression in ovarian cancer: role in cell proliferation and response to oxidative stressQ24336513
Complex relationship between TCTP, microtubules and actin microfilaments regulates cell shape in normal and cancer cellsQ24634268
EBP1, an ErbB3-binding protein, is decreased in prostate cancer and implicated in hormone resistanceQ24646417
Repression of E2F1-mediated transcription by the ErbB3 binding protein Ebp1 involves histone deacetylasesQ24680884
TCTP protects from apoptotic cell death by antagonizing bax functionQ27649850
The translationally controlled tumour protein (TCTP)Q28235318
Signaling via ErbB2 and ErbB3 associates with resistance and epidermal growth factor receptor (EGFR) amplification with sensitivity to EGFR inhibitor gefitinib in head and neck squamous cell carcinoma cellsQ28250203
The histone deacetylase inhibitor and chemotherapeutic agent suberoylanilide hydroxamic acid (SAHA) induces a cell-death pathway characterized by cleavage of Bid and production of reactive oxygen speciesQ28349324
Integrative analysis of proteomic signatures, mutations, and drug responsiveness in the NCI 60 cancer cell line setQ28389579
Retracted: Vimentin Is a Novel Anti-Cancer Therapeutic Target; Insights from In Vitro and In Vivo Mice Xenograft StudiesQ28473693
Principles of cancer therapy: oncogene and non-oncogene addictionQ29616779
Functional proteomics analysis of signal transduction pathways of the platelet-derived growth factor beta receptorQ30636308
Proteomic profiling of pancreatic ductal carcinoma cell lines treated with trichostatin-A.Q33187257
Retinoic acid-mediated down-regulation of ENO1/MBP-1 gene products caused decreased invasiveness of the follicular thyroid carcinoma cell linesQ33390295
Increased expression of enolase alpha in human breast cancer confers tamoxifen resistance in human breast cancer cellsQ33490663
Characterization of side population cells from laryngeal cancer cell linesQ33525639
Activation of the unfolded protein response contributes toward the antitumor activity of vorinostatQ33588300
Voltage dependent anion channel-1 regulates death receptor mediated apoptosis by enabling cleavage of caspase-8.Q33636849
Role of thioredoxin in the response of normal and transformed cells to histone deacetylase inhibitorsQ33697130
Histone deacetylase inhibitors activate NF-kappaB in human leukemia cells through an ATM/NEMO-related pathwayQ33744417
Heterogeneous nuclear ribonucleoprotein H blocks MST2-mediated apoptosis in cancer cells by regulating A-Raf transcriptionQ33893105
Transcriptional induction of GRP78/BiP by histone deacetylase inhibitors and resistance to histone deacetylase inhibitor-induced apoptosis.Q33926784
Understanding resistance to EGFR inhibitors-impact on future treatment strategiesQ34088424
The focusing positions of polypeptides in immobilized pH gradients can be predicted from their amino acid sequencesQ34336945
Metabolism and proliferation share common regulatory pathways in cancer cellsQ34419460
Histone deacetylase inhibitors in cancer therapyQ34659283
Phase I study of an oral histone deacetylase inhibitor, suberoylanilide hydroxamic acid, in patients with advanced cancerQ35758280
Multiple-target drugs: inhibitors of heat shock protein 90 and of histone deacetylase.Q36109012
Discovery and development of SAHA as an anticancer agentQ36745383
Histone deacetylase inhibitors: a new wave of molecular targeted anticancer agents.Q37066999
Development of vorinostat: current applications and future perspectives for cancer therapyQ37381104
p21CIP1 attenuates Ras- and c-Myc-dependent breast tumor epithelial mesenchymal transition and cancer stem cell-like gene expression in vivo.Q37419204
HDACi--targets beyond chromatin.Q37430947
Neuroendocrine differentiation of LNCaP cells suggests: VDAC in the cell membrane is involved in the extrinsic apoptotic pathwayQ37504211
HDAC inhibitor vorinostat enhances the antitumor effect of gefitinib in squamous cell carcinoma of head and neck by modulating ErbB receptor expression and reverting EMT.Q39527047
Negative regulation of p53 by the long isoform of ErbB3 binding protein Ebp1 in brain tumorsQ39628667
Epithelial-to-mesenchymal transition and c-myc expression are the determinants of cetuximab-induced enhancement of squamous cell carcinoma radioresponse.Q39706465
Identification of biomarkers in human head and neck tumor cell lines that predict for in vitro sensitivity to gefitinibQ39707468
Treatment with panobinostat induces glucose-regulated protein 78 acetylation and endoplasmic reticulum stress in breast cancer cells.Q39718130
Synergistic antitumor effect between vorinostat and topotecan in small cell lung cancer cells is mediated by generation of reactive oxygen species and DNA damage-induced apoptosisQ39779497
An integrated humoral and cellular response is elicited in pancreatic cancer by alpha-enolase, a novel pancreatic ductal adenocarcinoma-associated antigenQ39854940
Modulation of thymidilate synthase and p53 expression by HDAC inhibitor vorinostat resulted in synergistic antitumor effect in combination with 5FU or raltitrexedQ39875582
Delta-crystallin enhancer binding factor 1 controls the epithelial to mesenchymal transition phenotype and resistance to the epidermal growth factor receptor inhibitor erlotinib in human head and neck squamous cell carcinoma linesQ39894634
A proteomic approach for evaluating the cell response to a novel histone deacetylase inhibitor in colon cancer cellsQ39978575
Inhibition of heregulin mediated MCF-7 breast cancer cell growth by the ErbB3 binding protein EBP1.Q40000114
Proteome analyses of the growth inhibitory effects of NCH-51, a novel histone deacetylase inhibitor, on lymphoid malignant cellsQ40095635
Induction of GRP78 by valproic acid is dependent upon histone deacetylase inhibitionQ40120317
Epithelial to mesenchymal transition predicts gefitinib resistance in cell lines of head and neck squamous cell carcinoma and non-small cell lung carcinomaQ40125585
Involvement of glyceraldehyde-3-phosphate dehydrogenase in tumor necrosis factor-related apoptosis-inducing ligand-mediated death of thyroid cancer cellsQ40125627
Restoring E-cadherin expression increases sensitivity to epidermal growth factor receptor inhibitors in lung cancer cell lines.Q40327522
MBP-1 physically associates with histone deacetylase for transcriptional repressionQ40942403
New strategies in head and neck cancer: understanding resistance to epidermal growth factor receptor inhibitorsQ41127315
Tpt1 activates transcription of oct4 and nanog in transplanted somatic nucleiQ41862279
Critical role of both p27KIP1 and p21CIP1/WAF1 in the antiproliferative effect of ZD1839 ('Iressa'), an epidermal growth factor receptor tyrosine kinase inhibitor, in head and neck squamous carcinoma cellsQ44323774
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell deathQ44863828
Complete elimination of colorectal tumor xenograft by combined manganese superoxide dismutase with tumor necrosis factor-related apoptosis-inducing ligand gene virotherapyQ45245923
PRDX4, a member of the peroxiredoxin family, is fused to AML1 (RUNX1) in an acute myeloid leukemia patient with a t(X;21)(p22;q22).Q47367777
2D-DIGE: comparative proteomics of cellular signalling pathwaysQ47982902
Epithelial-mesenchymal transition and the invasive potential of tumors.Q51959766
P433issue18
P304page(s)3725-3742
P577publication date2011-09-01
P1433published inProteomicsQ15614164
P1476titleProteomic analysis identifies differentially expressed proteins after HDAC vorinostat and EGFR inhibitor gefitinib treatments in Hep-2 cancer cells
P478volume11

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cites work (P2860)
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