Structure and biological actions of lactoferrin

scientific article

Structure and biological actions of lactoferrin is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1007/BF02018081
P698PubMed publication ID10887502

P2093author name stringNuijens JH
van Berkel PH
Schanbacher FL
P2860cites workModulation of natural killer and lymphokine-activated killer cell cytotoxicity by lactoferrinQ68096366
P-selectin-dependent leukocyte recruitment and intestinal mucosal injury induced by lactoferrinQ71625289
Proposed mechanisms for the involvement of lactoferrin in the hydrolysis of nucleic acidsQ71694901
Delineation of the glycosaminoglycan-binding site in the human inflammatory response protein lactoferrinQ72196653
Three-dimensional structure of lactoferrin in various functional statesQ72267523
Study on the binding of lactotransferrin (lactoferrin) to human PHA-activated lymphocytes and non-activated platelets. Localisation and description of the receptor-binding siteQ72267527
Antimicrobial peptides of lactoferrinQ72267549
Primary and three-dimensional structure of lactotransferrin (lactoferrin) glycansQ72267551
Lipopolysaccharide-inactivating activity of neutrophils is due to lactoferrinQ72334681
Neutralization of heparin activity by neutrophil lactoferrinQ72386117
Expression of human lactoferrin in milk of transgenic miceQ72456336
Removal of 14 N-terminal amino acids of lactoferrin enhances its affinity for parenchymal liver cells and potentiates the inhibition of beta- very low density lipoprotein bindingQ72660701
Biological role of lactoferrinQ24678066
Iron acquisition by Helicobacter pylori: importance of human lactoferrinQ33601247
Antiviral effects of plasma and milk proteins: lactoferrin shows potent activity against both human immunodeficiency virus and human cytomegalovirus replication in vitroQ34300988
Lactoferrin: a general reviewQ34305115
Physical characteristics and polymerization during iron saturation of lactoferrin, a myelopoietic regulatory molecule with suppressor activityQ34311633
Structure of the bovine lactoferrin-encoding gene and its promoterQ34342644
Lactoferrin gene promoter in human and mouse. Analogous and dissimilar characteristics.Q36704894
Structural determination of two N-linked glycans isolated from recombinant human lactoferrin expressed in BHK cellsQ36706838
The role of lactoferrin in the nonspecific immune response on the ocular surfaceQ37836074
Proteins of iron storage and transportQ37940648
The effects of lactoferrin on gram-negative bacteriaQ40532236
Lactoferrin in infant formulaeQ40582722
Bovine mammary lactoferrin: implications from messenger ribonucleic acid (mRNA) sequence and regulation contrary to other milk proteinsQ40727643
Lactoferrin: molecular structure and biological functionQ40926159
Glycosylated and unglycosylated human lactoferrins both bind iron and show identical affinities towards human lysozyme and bacterial lipopolysaccharide, but differ in their susceptibilities towards tryptic proteolysisQ41271251
Effect of intracellular iron depletion by picolinic acid on expression of the lactoferrin receptor in the human colon carcinoma cell subclone HT29-18-C1.Q41338309
Lactoferrin down-modulates the activity of the granulocyte macrophage colony-stimulating factor promoter in interleukin-1 beta-stimulated cellsQ41344537
Sequence specificity and transcriptional activation in the binding of lactoferrin to DNA.Q41368241
Iron saturation alters the effect of lactoferrin on the proliferation and differentiation of human enterocytes (Caco-2 cells).Q41398210
The relationship between low density lipoprotein-related protein/alpha 2-macroglobulin (alpha 2M) receptors and the newly described alpha 2M signaling receptor.Q41662360
Lactoferrin-lipopolysaccharide interactions. Effect on lactoferrin binding to monocyte/macrophage-differentiated HL-60 cellsQ41699629
Lactoferrin-lipopolysaccharide interaction: involvement of the 28-34 loop region of human lactoferrin in the high-affinity binding to Escherichia coli 055B5 lipopolysaccharideQ41998225
Bovine lactoferrin in involuting mammary tissueQ42512437
Human lactoferrin inhibits growth of solid tumors and development of experimental metastases in mice.Q42799210
Isolated rat hepatocytes acquire iron from lactoferrin by endocytosisQ42822245
Interaction of lactoferrin with sequestered transition metal ionsQ46267365
A system for production of commercial quantities of human lactoferrin: a broad spectrum natural antibioticQ47948413
Characterization of a mitogen-response unit in the mouse lactoferrin gene promoter.Q52217167
Expression of alpha-lactalbumin, alpha-S1-casein, and lactoferrin genes is heterogeneous in sheep and cattle mammary tissueQ67534984
P433issue3
P304page(s)285-295
P577publication date1996-07-01
P1433published inJournal of Mammary Gland Biology and NeoplasiaQ15724460
P1476titleStructure and biological actions of lactoferrin
P478volume1

Reverse relations

cites work (P2860)
Q36850113A high-throughput method for the quantification of iron saturation in lactoferrin preparations
Q35975928A review of the effects of breastfeeding on respiratory infections, atopy, and childhood asthma
Q78377142Analytical cation-exchange chromatography to assess the identity, purity, and N-terminal integrity of human lactoferrin
Q40662721Arginine 25 and Arginine 28 of lactoferrin are critical for effective heparin neutralization in blood
Q35593485Bioactive peptides and proteins
Q44438079Bovine lactoferrin binds to insulin-like growth factor-binding protein-3
Q24290527Candidacidal activities of human lactoferrin peptides derived from the N terminus
Q36272601Cell-specific targeting of lipid-based carriers for ODN and DNA.
Q74583067Characterization of monoclonal antibodies against human lactoferrin
Q50529864Characterization of recombinant human lactoferrin secreted in milk of transgenic mice.
Q27316874Classic selective sweeps revealed by massive sequencing in cattle
Q34762331Colostral and milk insulin-like growth factors and related substances: mammary gland and neonatal (intestinal and systemic) targets
Q43569961Comprehensive characterization of the site-specific N-glycosylation of wild-type and recombinant human lactoferrin expressed in the milk of transgenic cloned cattle
Q52122320Detection of exon polymorphisms in the human lactoferrin gene.
Q52752666Dietary N-Glycans from Bovine Lactoferrin and TLR Modulation.
Q37728982Effect of lactoferrin- and transferrin-conjugated polymersomes in brain targeting: in vitro and in vivo evaluations.
Q47856678Effect of substratum on growth, cell morphology and lactoferrin synthesis and secretion in bovine mammary cell culture
Q40768913Effects of lactoferrin on collagen gel contractile activity and myosin light chain phosphorylation in human fibroblasts.
Q35015653Engineering immunity in the mammary gland
Q39721547Evaluation of the protective effect of bovine lactoferrin against lipopolysaccharides in a bovine mammary epithelial cell line
Q37155141Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease
Q33679837Expression of functional immunomodulatory and anti-inflammatory factors in human milk.
Q42817490Fungicidal activity of human lactoferrin-derived peptides based on the antimicrobial αβ region
Q36374743Growth phase-dependent response of Helicobacter pylori to iron starvation
Q84073469High concentration of human lactoferrin in milk of rhLf-transgenic cows relieves signs of bovine experimental Staphylococcus chromogenes intramammary infection
Q39518711Human lactoferrin and peptides derived from its N terminus are highly effective against infections with antibiotic-resistant bacteria.
Q50103303In vitro growth responses of bifidobacteria and enteropathogens to bovine and human lactoferrin
Q44928090In vivo effects of bifidobacteria and lactoferrin on gut endotoxin concentration and mucosal immunity in Balb/c mice
Q37350006Influence of dietary components on development of the microbiota in single-stomached species
Q36208305Inhibition of Candida albicans Biofilm Formation by the Synthetic Lactoferricin Derived Peptide hLF1-11.
Q37246851Inhibitory Effects of Synthetic Peptides Containing Bovine Lactoferrin C-lobe Sequence on Bacterial Growth
Q37575082Inhibitory effects of human lactoferrin on U14 cervical carcinoma through upregulation of the immune response
Q33904093Insulin-like growth factor (IGF) system in the bovine mammary gland and milk
Q34462620Iron status in mice carrying a targeted disruption of lactoferrin
Q43112188IsdA protects Staphylococcus aureus against the bactericidal protease activity of apolactoferrin
Q37897330Lactoferrin a multiple bioactive protein: an overview.
Q36692263Lactoferrin acts as an alarmin to promote the recruitment and activation of APCs and antigen-specific immune responses
Q37353959Lactoferrin and cancer disease prevention.
Q34573857Lactoferrin and host defense
Q34573846Lactoferrin gene expression and regulation: an overview
Q40765436Lactoferrin is synthesized by activated microglia in the human substantia nigra and its synthesis by the human microglial CHME cell line is upregulated by tumor necrosis factor alpha or 1-methyl-4-phenylpyridinium treatment
Q64854159Lactoferrin is synthesized by mouse brain tissue and its expression is enhanced after MPTP treatment
Q43927301Lactoferrin-binding proteins in Bifidobacterium bifidum
Q45231378Large scale production of recombinant human lactoferrin in the milk of transgenic cows
Q38355997Low density lipoprotein receptor-related protein (LRP) is required for lactoferrin-enhanced collagen gel contractile activity of human fibroblasts.
Q35682256Mammary expression of new genes to combat mastitis
Q35015655Mammary gland immunity and mastitis susceptibility
Q28285428Milk fat globule glycoproteins in human milk and in gastric aspirates of mother's milk-fed preterm infants
Q41990276N-terminal stretch Arg2, Arg3, Arg4 and Arg5 of human lactoferrin is essential for binding to heparin, bacterial lipopolysaccharide, human lysozyme and DNA
Q33887964Nutritional and physiological criteria in the assessment of milk protein quality for humans
Q33962816Oligosaccharides and glycoconjugates in human milk: their role in host defense
Q36375788One of Two Human Lactoferrin Variants Exhibits Increased Antibacterial and Transcriptional Activation Activities and Is Associated with Localized Juvenile Periodontitis
Q78241752Over-expression of the murine polymeric immunoglobulin receptor gene in the mammary gland of transgenic mice
Q40969107Receptor-mediated transcytosis of lactoferrin through the blood-brain barrier.
Q44675112Recombinant human lactoferrin ingestion attenuates indomethacin-induced enteropathy in vivo in healthy volunteers
Q80519698Recombinant porcine lactoferrin expressed in the milk of transgenic mice protects neonatal mice from a lethal challenge with enterovirus type 71
Q40060375Targeting of stabilized plasmid lipid particles to hepatocytes in vivo by means of coupled lactoferrin
Q26830772The Immunology of Mammary Gland of Dairy Ruminants between Healthy and Inflammatory Conditions
Q46682069The N-Terminus of Human Lactoferrin Displays Anti-biofilm Activity on Candida parapsilosis in Lumen Catheters
Q40684957The bovine lactoferrin region responsible for promoting the collagen gel contractile activity of human fibroblasts.
Q35129350The comparative biology of whey proteins
Q79139059The prospects of modifying the antimicrobial properties of milk
Q30351524The protein structure of recombinant human lactoferrin produced in the milk of transgenic cows closely matches the structure of human milk-derived lactoferrin.
Q37906773Tumor necrosis factor-α-induced inflammatory responses in cattle

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