Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila

scientific article

Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID1206948
P698PubMed publication ID8770597

P2093author name stringM Stern
W M Saxton
D D Hurd
P2860cites workConduction in the giant nerve fiber pathway in temperature-sensitive paralytic mutants of DrosophilaQ43418739
Examination of paralysis in Drosophila temperature-sensitive paralytic mutations affecting sodium channels; a proposed mechanism of paralysisQ43653258
napts, a mutation affecting sodium channel activity in Drosophila, is an allele of mle, a regulator of X chromosome transcriptionQ44460500
Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegansQ47069257
A distinct potassium channel polypeptide encoded by the Drosophila eag locusQ48222242
Molecular analysis of the para locus, a sodium channel gene in DrosophilaQ48287063
Drosophila mutants with opposing effects on nerve excitability: genetic and spatial interactions in repetitive firingQ51862671
Identification and characterization of inebriated, a gene affecting neuronal excitability in DrosophilaQ52441460
The tip-E mutation of Drosophila decreases saxitoxin binding and interacts with other mutations affecting nerve membrane excitability.Q52451735
Neurogenetic analysis of Drosophila mutations affecting sodium channels: synergistic effects on viability and nerve conduction in double mutants involving tip-E.Q52451737
Action potentials in normal and Shaker mutant Drosophila.Q52466567
Genetic manipulation of motor output in shaker mutants of Drosophila.Q52473820
Failure of a single-headed kinesin to track parallel to microtubule protofilamentsQ59053953
Two types of mutants affecting voltage-sensitive sodium channels in Drosophila melanogasterQ59096316
Molecular phylogeny of the kinesin family of microtubule motor proteinsQ72864168
The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursorsQ24307447
Kinesin family in murine central nervous systemQ24642717
The effect of temperature on the electrical activity of the giant axon of the squidQ28284138
Distinct sets of SEC genes govern transport vesicle formation and fusion early in the secretory pathwayQ29618501
Glutamate and substance P coexist in primary afferent terminals in the superficial laminae of spinal cordQ33658035
Dosage effects of a Drosophila sodium channel gene on behavior and axonal excitabilityQ33956082
Cytogenetic and molecular localization of tipE: a gene affecting sodium channels in Drosophila melanogasterQ33964901
The behavior of four neurological mutants of DrosophilaQ33985582
Cellular and molecular biology of voltage-gated sodium channelsQ34238906
Molecular characterization of Shaker, a Drosophila gene that encodes a potassium channelQ34396702
Neurogenetic studies of ion channels in DrosophilaQ35234802
Evidence for alternating head catalysis by kinesin during microtubule-stimulated ATP hydrolysisQ35600643
Mechanisms of Fast and Slow Axonal TransportQ36649410
Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophila larvaeQ36773960
Molecular motors in the nervous systemQ37110065
Temperature-sensitive mutations in Drosophila melanogaster. VII. A mutation (para-ts) causing reversible adult paralysisQ37474470
A Drosophila mutant with a temperature-sensitive block in nerve conductionQ37593423
Identification and partial characterization of six members of the kinesin superfamily in DrosophilaQ37597638
Genetic analysis of the yeast cytoskeleton.Q39696747
Intracellular transport in neuronsQ40098915
Molecular motors and cell motility in the brainQ40689762
With apologies to scheherazade: tails of 1001 kinesin motorsQ40722178
Axonal transport and the cytoskeletonQ40790279
Motor proteins. 1: kinesinsQ40927524
A mutation of the Drosophila sodium pump alpha subunit gene results in bang-sensitive paralysisQ41045006
Cloning of genomic and complementary DNA from Shaker, a putative potassium channel gene from DrosophilaQ41250216
Indirect Suppression Involving Behavioral Mutants with Altered Nerve Excitability in DROSOPHILA MELANOGASTER.Q41859275
Kinesin heavy chain is essential for viability and neuromuscular functions in Drosophila, but mutants show no defects in mitosisQ42620353
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectDrosophilaQ312154
P304page(s)195-204
P577publication date1996-01-01
P1433published inGeneticsQ3100575
P1476titleMutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila
P478volume142

Reverse relations

cites work (P2860)
Q36897049A developmentally regulated kinesin-related motor protein from Dictyostelium discoideum
Q36377569Barentsz is essential for the posterior localization of oskar mRNA and colocalizes with it to the posterior pole
Q24290899Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules
Q34705114Clonal tests of conventional kinesin function during cell proliferation and differentiation
Q34143936Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxia
Q34021550Drosophila PAT1 is required for Kinesin-1 to transport cargo and to maximize its motility
Q24315910Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport
Q34605324Increased transmitter release and aberrant synapse morphology in a Drosophila calmodulin mutant
Q47070218Kinesin heavy chain function in Drosophila glial cells controls neuronal activity.
Q36289116Kinesin light chains are essential for axonal transport in Drosophila
Q33968701Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila
Q24671932Kinesin-II, a membrane traffic motor in axons, axonemes, and spindles
Q30513860Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila
Q37113461Molecular motors and synaptic assembly
Q27320509Nebula/DSCR1 upregulation delays neurodegeneration and protects against APP-induced axonal transport defects by restoring calcineurin and GSK-3β signaling
Q28536678Small molecule suppressors of Drosophila kinesin deficiency rescue motor axon development in a zebrafish model of spinal muscular atrophy
Q52173667Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila.
Q27311512The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila
Q54107587The Presenilin loop region is essential for Glycogen synthase kinase 3 beta mediated functions on motor proteins during axonal transport.
Q37447429The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation
Q46869302Two kinesins drive anterograde neuropeptide transport.

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