Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila

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Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila is …
instance of (P31):
scholarly articleQ13442814

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P932PMC publication ID1207603
P698PubMed publication ID8913751

P2093author name stringW M Saxton
D D Hurd
P2860cites workThe neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursorsQ24307447
KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondriaQ28287180
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxinQ29620437
Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides.Q30434342
Drosophila kinesin: characterization of microtubule motility and ATPaseQ33553304
Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in DrosophilaQ33966514
Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmissionQ34317092
Effects of kinesin mutations on neuronal functionsQ35467857
Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryosQ36292831
Microtubule-dependent control of cell shape and pseudopodial activity is inhibited by the antibody to kinesin motor domainQ36534685
Mechanisms of Fast and Slow Axonal TransportQ36649410
Electron microscopy and EM immunocytochemistryQ36699175
Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophila larvaeQ36773960
Molecular motors in the nervous systemQ37110065
Inhibition of kinesin synthesis in vivo inhibits the rapid transport of representative proteins for three transport vesicle classes into the axon.Q38296194
Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos.Q39104424
Properties of the larval neuromuscular junction in Drosophila melanogasterQ39122960
Long-term regulation of short-term transmitter release properties: retrograde signaling and synaptic developmentQ40387653
Amyotrophic lateral sclerosis is a multifactorial diseaseQ40546531
Amyotrophic lateral sclerosis: recent insights from genetics and transgenic miceQ40612435
Retrograde signaling in the formation and maintenance of the neuromuscular junctionQ40695391
The endosomal-lysosomal system of neurons: new rolesQ40964699
The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organellesQ41264903
Polarity orientation of axonal microtubulesQ41438244
Genetic analysis of Fasciclin II in Drosophila: defasciculation, refasciculation, and altered fasciculation.Q46004298
Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidanceQ46045692
Paralysis and early death in cysteine string protein mutants of DrosophilaQ46085105
Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapseQ48240408
The organisation of the axonal reticulum at a ligation, in in vitro incubated bovine splenic nervesQ49105943
Synaptic plasticity in Drosophila memory and hyperexcitable mutants: role of cAMP cascadeQ52078998
Morphological plasticity of motor axons in Drosophila mutants with altered excitabilityQ52445038
Interfering with the runnersQ60074097
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron diseaseQ70633175
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosisQ70633178
Axonal ion channel dysfunction in amyotrophic lateral sclerosisQ71681845
Molecular Biology of Neuronal Geometry: Expression of Neurofilament Genes Influences Axonal DiameterQ72732800
P433issue3
P407language of work or nameEnglishQ1860
P921main subjectphenotypeQ104053
DrosophilaQ312154
motor neuron diseaseQ3221083
Synaptotagmin 1 Dmel_CG3139Q29812939
Kinesin heavy chain Dmel_CG7765Q29819829
P304page(s)1075-1085
P577publication date1996-11-01
P1433published inGeneticsQ3100575
P1476titleKinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila
P478volume144

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