scholarly article | Q13442814 |
P2093 | author name string | W M Saxton | |
D D Hurd | |||
P2860 | cites work | The neuron-specific kinesin superfamily protein KIF1A is a unique monomeric motor for anterograde axonal transport of synaptic vesicle precursors | Q24307447 |
KIF1B, a novel microtubule plus end-directed monomeric motor protein for transport of mitochondria | Q28287180 | ||
Synaptic vesicle fusion complex contains unc-18 homologue bound to syntaxin | Q29620437 | ||
Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides. | Q30434342 | ||
Drosophila kinesin: characterization of microtubule motility and ATPase | Q33553304 | ||
Mutation of the axonal transport motor kinesin enhances paralytic and suppresses Shaker in Drosophila | Q33966514 | ||
Genetic and electrophysiological studies of Drosophila syntaxin-1A demonstrate its role in nonneuronal secretion and neurotransmission | Q34317092 | ||
Effects of kinesin mutations on neuronal functions | Q35467857 | ||
Antibodies to horseradish peroxidase as specific neuronal markers in Drosophila and in grasshopper embryos | Q36292831 | ||
Microtubule-dependent control of cell shape and pseudopodial activity is inhibited by the antibody to kinesin motor domain | Q36534685 | ||
Mechanisms of Fast and Slow Axonal Transport | Q36649410 | ||
Electron microscopy and EM immunocytochemistry | Q36699175 | ||
Differential ultrastructure of synaptic terminals on ventral longitudinal abdominal muscles in Drosophila larvae | Q36773960 | ||
Molecular motors in the nervous system | Q37110065 | ||
Inhibition of kinesin synthesis in vivo inhibits the rapid transport of representative proteins for three transport vesicle classes into the axon. | Q38296194 | ||
Neural-specific carbohydrate moiety shared by many surface glycoproteins in Drosophila and grasshopper embryos. | Q39104424 | ||
Properties of the larval neuromuscular junction in Drosophila melanogaster | Q39122960 | ||
Long-term regulation of short-term transmitter release properties: retrograde signaling and synaptic development | Q40387653 | ||
Amyotrophic lateral sclerosis is a multifactorial disease | Q40546531 | ||
Amyotrophic lateral sclerosis: recent insights from genetics and transgenic mice | Q40612435 | ||
Retrograde signaling in the formation and maintenance of the neuromuscular junction | Q40695391 | ||
The endosomal-lysosomal system of neurons: new roles | Q40964699 | ||
The movement of membranous organelles in axons. Electron microscopic identification of anterogradely and retrogradely transported organelles | Q41264903 | ||
Polarity orientation of axonal microtubules | Q41438244 | ||
Genetic analysis of Fasciclin II in Drosophila: defasciculation, refasciculation, and altered fasciculation. | Q46004298 | ||
Ectopic and increased expression of Fasciclin II alters motoneuron growth cone guidance | Q46045692 | ||
Paralysis and early death in cysteine string protein mutants of Drosophila | Q46085105 | ||
Expression of synaptotagmin in Drosophila reveals transport and localization of synaptic vesicles to the synapse | Q48240408 | ||
The organisation of the axonal reticulum at a ligation, in in vitro incubated bovine splenic nerves | Q49105943 | ||
Synaptic plasticity in Drosophila memory and hyperexcitable mutants: role of cAMP cascade | Q52078998 | ||
Morphological plasticity of motor axons in Drosophila mutants with altered excitability | Q52445038 | ||
Interfering with the runners | Q60074097 | ||
Increased expression of neurofilament subunit NF-L produces morphological alterations that resemble the pathology of human motor neuron disease | Q70633175 | ||
Progressive neuronopathy in transgenic mice expressing the human neurofilament heavy gene: a mouse model of amyotrophic lateral sclerosis | Q70633178 | ||
Axonal ion channel dysfunction in amyotrophic lateral sclerosis | Q71681845 | ||
Molecular Biology of Neuronal Geometry: Expression of Neurofilament Genes Influences Axonal Diameter | Q72732800 | ||
P433 | issue | 3 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | phenotype | Q104053 |
Drosophila | Q312154 | ||
motor neuron disease | Q3221083 | ||
Synaptotagmin 1 Dmel_CG3139 | Q29812939 | ||
Kinesin heavy chain Dmel_CG7765 | Q29819829 | ||
P304 | page(s) | 1075-1085 | |
P577 | publication date | 1996-11-01 | |
P1433 | published in | Genetics | Q3100575 |
P1476 | title | Kinesin mutations cause motor neuron disease phenotypes by disrupting fast axonal transport in Drosophila | |
P478 | volume | 144 |
Q28079299 | A Case for Microtubule Vulnerability in Amyotrophic Lateral Sclerosis: Altered Dynamics During Disease |
Q36897049 | A Developmentally Regulated Kinesin-related Motor Protein fromDictyostelium discoideum |
Q38720656 | A STRIPAK complex mediates axonal transport of autophagosomes and dense core vesicles through PP2A regulation |
Q33374520 | A functional misexpression screen uncovers a role for enabled in progressive neurodegeneration. |
Q30009119 | A high affinity RIM-binding protein/Aplip1 interaction prevents the formation of ectopic axonal active zones |
Q24632247 | A kinesin heavy chain (KIF5A) mutation in hereditary spastic paraplegia (SPG10) |
Q35017294 | A kinesin mutation that uncouples motor domains and desensitizes the gamma-phosphate sensor |
Q35981876 | A large-scale RNAi screen identifies functional classes of genes shaping synaptic development and maintenance |
Q52771784 | A presynaptic role of microtubule-associated protein 1/Futsch in Drosophila: regulation of active zone number and neurotransmitter release |
Q37170196 | A quantitative examination of the role of cargo-exerted forces in axonal transport |
Q35474993 | A role for kinesin heavy chain in controlling vesicle transport into dendrites inDrosophila |
Q93380092 | A stochastic model that explains axonal organelle pileups induced by a reduction of molecular motors |
Q36285684 | A tropomyosin-2 mutation suppresses a troponin I myopathy in Drosophila |
Q30477753 | APLIP1, a kinesin binding JIP-1/JNK scaffold protein, influences the axonal transport of both vesicles and mitochondria in Drosophila |
Q30476113 | Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1. |
Q26768215 | Alterations in Mitochondrial Quality Control in Alzheimer's Disease |
Q28512320 | Alzheimer's presenilin 1 mutations impair kinesin-based axonal transport |
Q30489361 | Amyloid precursor protein-induced axonopathies are independent of amyloid-beta peptides |
Q35860341 | Amyotrophic lateral sclerosis-associated mutant VAPBP56S perturbs calcium homeostasis to disrupt axonal transport of mitochondria |
Q30539096 | An organelle gatekeeper function for Caenorhabditis elegans UNC-16 (JIP3) at the axon initial segment |
Q33588589 | Anatomical distributional defects in mutant genes associated with dominant intermediate Charcot-Marie-Tooth disease type C in an adenovirus-mediated mouse model |
Q97570181 | Axonal transport and neurodegenerative disease: vesicle-motor complex formation and their regulation |
Q36117548 | Axonal transport of mitochondria requires milton to recruit kinesin heavy chain and is light chain independent |
Q37621463 | Axonal transport: how high microtubule density can compensate for boundary effects in small-caliber axons |
Q33511955 | Bruchpilot in ribbon-like axonal agglomerates, behavioral defects, and early death in SRPK79D kinase mutants of Drosophila |
Q24290899 | Cargo of kinesin identified as JIP scaffolding proteins and associated signaling molecules |
Q34455671 | Cell biology and genetics of root hair formation inArabidopsis thaliana |
Q38006054 | Cellular Pathways of Hereditary Spastic Paraplegia |
Q34705114 | Clonal tests of conventional kinesin function during cell proliferation and differentiation |
Q36923139 | Contribution of the GTPase Domain to the Subcellular Localization of Dynamin in the NematodeCaenorhabditis elegans |
Q33943288 | Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways |
Q24675118 | Control of a kinesin-cargo linkage mechanism by JNK pathway kinases |
Q36935494 | Cytoplasmic dynein, the dynactin complex, and kinesin are interdependent and essential for fast axonal transport |
Q24683600 | Defective kinesin heavy chain behavior in mouse kinesin light chain mutants |
Q34143936 | Defects in mitochondrial axonal transport and membrane potential without increased reactive oxygen species production in a Drosophila model of Friedreich ataxia |
Q27315692 | Disruption of axonal transport perturbs bone morphogenetic protein (BMP)--signaling and contributes to synaptic abnormalities in two neurodegenerative diseases |
Q47070552 | Drosophila Acyl-CoA synthetase long-chain family member 4 regulates axonal transport of synaptic vesicles and is required for synaptic development and transmission. |
Q38948778 | Drosophila Neuronal Injury Follows a Temporal Sequence of Cellular Events Leading to Degeneration at the Neuromuscular Junction |
Q30442054 | Drosophila roadblock and Chlamydomonas LC7: a conserved family of dynein-associated proteins involved in axonal transport, flagellar motility, and mitosis |
Q24300248 | Dynactin is required for coordinated bidirectional motility, but not for dynein membrane attachment |
Q42542002 | Dynamic microtubule organization and mitochondrial transport are regulated by distinct Kinesin-1 pathways |
Q34360933 | Dysfunction of heterotrimeric kinesin-2 in rod photoreceptor cells and the role of opsin mislocalization in rapid cell death. |
Q34069992 | ER sliding dynamics and ER-mitochondrial contacts occur on acetylated microtubules |
Q24315910 | Effects of ALS-related SOD1 mutants on dynein- and KIF5-mediated retrograde and anterograde axonal transport |
Q40068903 | Effects of imaging conditions on mitochondrial transport and length in larval motor axons of Drosophila |
Q36317703 | Enhanced β-secretase processing alters APP axonal transport and leads to axonal defects |
Q34804852 | Epsin 1 Promotes Synaptic Growth by Enhancing BMP Signal Levels in Motoneuron Nuclei. |
Q33998992 | Evidence that myosin activity opposes microtubule-based axonal transport of mitochondria |
Q24647184 | GARS axonopathy: not every neuron's cup of tRNA |
Q37817723 | Hereditary spastic paraplegias: membrane traffic and the motor pathway |
Q30480995 | Identification of an axonal kinesin-3 motor for fast anterograde vesicle transport that facilitates retrograde transport of neuropeptides |
Q36087937 | Identification of pharmacological targets in amyotrophic lateral sclerosis through genomic analysis of deregulated genes and pathways. |
Q41235266 | Imaging axonal transport of mitochondria |
Q47070547 | In vivo properties of the Drosophila inebriated-encoded neurotransmitter transporter. |
Q38614630 | In vivo visualization of synaptic vesicles within Drosophila larval segmental axons |
Q43092408 | Increasing Tip60 HAT Levels Rescues Axonal Transport Defects and Associated Behavioral Phenotypes in aDrosophilaAlzheimer's Disease Model |
Q37058124 | Independent pathways downstream of the Wnd/DLK MAPKKK regulate synaptic structure, axonal transport, and injury signaling |
Q30577687 | Interactions between Tau and α-synuclein augment neurotoxicity in a Drosophila model of Parkinson's disease |
Q27324452 | JNK-interacting protein 3 mediates the retrograde transport of activated c-Jun N-terminal kinase and lysosomes |
Q47070218 | Kinesin Heavy Chain Function inDrosophilaGlial Cells Controls Neuronal Activity |
Q36289116 | Kinesin Light Chains Are Essential for Axonal Transport in Drosophila |
Q36379939 | Kinesin delivers: identifying receptors for motor proteins |
Q34287420 | Kinesin molecular motors: transport pathways, receptors, and human disease |
Q47616417 | Kinesin superfamily: roles in breast cancer, patient prognosis and therapeutics. |
Q30477062 | Kinesin-1 and Dynein are the primary motors for fast transport of mitochondria in Drosophila motor axons |
Q34592517 | Kinesin-1 tail autoregulation and microtubule-binding regions function in saltatory transport but not ooplasmic streaming |
Q30652986 | Kinesin-1-powered microtubule sliding initiates axonal regeneration in Drosophila cultured neurons |
Q36294764 | Kinesin-II is required for axonal transport of choline acetyltransferase in Drosophila. |
Q33764338 | Kinesin-II, coming and going |
Q34182907 | Kinesins at a glance |
Q35482203 | Lethal kinesin mutations reveal amino acids important for ATPase activation and structural coupling |
Q27334950 | Load-induced enhancement of Dynein force production by LIS1-NudE in vivo and in vitro |
Q58718237 | MAP7 regulates axon morphogenesis by recruiting kinesin-1 to microtubules and modulating organelle transport |
Q57049982 | Metabolic regulation and glucose sensitivity of cortical radial glial cells |
Q41634350 | Methods to identify and analyze gene products involved in neuronal intracellular transport using Drosophila. |
Q24674193 | Missense mutation in the tubulin-specific chaperone E (Tbce) gene in the mouse mutant progressive motor neuronopathy, a model of human motoneuron disease |
Q27302144 | Mitochondria-cytoskeleton associations in mammalian cytokinesis |
Q33585950 | Mitochondrial Aspects of Synaptic Dysfunction in Alzheimer's Disease |
Q28291981 | Mitochondrial Trafficking in Neurons |
Q41664833 | Mitochondrial dynamics in Parkinson's disease: a role for α-synuclein? |
Q37677601 | Mitochondrial trafficking and anchoring in neurons: New insight and implications |
Q37261121 | Mitochondrial transport and docking in axons |
Q30513908 | Molecular crowding creates traffic jams of kinesin motors on microtubules |
Q30513860 | Molecular motor function in axonal transport in vivo probed by genetic and computational analysis in Drosophila |
Q35759173 | Mutational Analysis of Rab3 Function for Controlling Active Zone Protein Composition at the Drosophila Neuromuscular Junction |
Q47717805 | Mutations in Caenorhabditis elegans cytoplasmic dynein components reveal specificity of neuronal retrograde cargo. |
Q27329180 | Negative regulation of active zone assembly by a newly identified SR protein kinase |
Q26781649 | Neurodegeneration and microtubule dynamics: death by a thousand cuts |
Q35935658 | Neurofibromatosis-like phenotype in Drosophila caused by lack of glucosylceramide extension |
Q36322059 | Oligodendroglial modulation of fast axonal transport in a mouse model of hereditary spastic paraplegia. |
Q28478671 | Organically modified silica nanoparticles are biocompatible and can be targeted to neurons in vivo |
Q36907760 | PATHOLOGIES OF AXONAL TRANSPORT IN NEURODEGENERATIVE DISEASES |
Q33503992 | PP2A and GSK-3beta act antagonistically to regulate active zone development |
Q36485486 | Paradigm lost: milton connects kinesin heavy chain to miro on mitochondria. |
Q21266563 | Pathways and genes differentially expressed in the motor cortex of patients with sporadic amyotrophic lateral sclerosis |
Q27316679 | Pavarotti/MKLP1 regulates microtubule sliding and neurite outgrowth in Drosophila neurons. |
Q34003129 | Paxillin inhibits HDAC6 to regulate microtubule acetylation, Golgi structure, and polarized migration |
Q34191628 | Protein turnover of the Wallenda/DLK kinase regulates a retrograde response to axonal injury |
Q36686132 | Rab3-GEF Controls Active Zone Development at the Drosophila Neuromuscular Junction. |
Q24632243 | Rat kinesin light chain 3 associates with spermatid mitochondria |
Q90407398 | Reduced TUBA1A tubulin causes defects in trafficking and impaired adult motor behavior |
Q34917230 | Regulation of axonal mitochondrial transport and its impact on synaptic transmission |
Q39432011 | Regulation of long-distance transport of mitochondria along microtubules |
Q35612981 | Regulation of mitochondrial transport in neurons |
Q41705560 | Restraint of presynaptic protein levels by Wnd/DLK signaling mediates synaptic defects associated with the kinesin-3 motor Unc-104. |
Q30804705 | Role of kinesin-1-based microtubule sliding in Drosophila nervous system development |
Q40328387 | Self-organized density patterns of molecular motors in arrays of cytoskeletal filaments |
Q30841609 | Single Molecule Investigation of Kinesin-1 Motility Using Engineered Microtubule Defects. |
Q28536678 | Small Molecule Suppressors of Drosophila Kinesin Deficiency Rescue Motor Axon Development in a Zebrafish Model of Spinal Muscular Atrophy |
Q33619594 | Sorting of Dendritic and Axonal Vesicles at the Pre-axonal Exclusion Zone. |
Q27329979 | Spastic paraplegia mutation N256S in the neuronal microtubule motor KIF5A disrupts axonal transport in a Drosophila HSP model |
Q27332721 | Spatial and temporal characteristics of normal and perturbed vesicle transport |
Q33788461 | Spectrin mutations that cause spinocerebellar ataxia type 5 impair axonal transport and induce neurodegeneration in Drosophila. |
Q35513705 | Stathmin is required for stability of the Drosophila neuromuscular junction. |
Q42750322 | Staufen targets coracle mRNA to Drosophila neuromuscular junctions and regulates GluRIIA synaptic accumulation and bouton number |
Q58115990 | Structural consequences of hereditary spastic paraplegia disease-related mutations in kinesin |
Q34503783 | Structure and function of ER membrane contact sites with other organelles |
Q35529786 | Syd/JIP3 and JNK signaling are required for myonuclear positioning and muscle function |
Q98188948 | Synapse development and maturation at the drosophila neuromuscular junction |
Q35128328 | Synaptic vesicle mobility and presynaptic F-actin are disrupted in a N-ethylmaleimide-sensitive factor allele of Drosophila |
Q34646100 | Syntabulin-kinesin-1 family member 5B-mediated axonal transport contributes to activity-dependent presynaptic assembly. |
Q24669723 | Syntabulin-mediated anterograde transport of mitochondria along neuronal processes |
Q52173667 | Targeted expression of truncated glued disrupts giant fiber synapse formation in Drosophila |
Q34163603 | The Caenorhabditis elegans JIP3 protein UNC-16 functions as an adaptor to link kinesin-1 with cytoplasmic dynein. |
Q30544013 | The Kinesin-3, Unc-104 Regulates Dendrite Morphogenesis and Synaptic Development in Drosophila |
Q27311512 | The Microtubule Regulatory Protein Stathmin Is Required to Maintain the Integrity of Axonal Microtubules in Drosophila |
Q30536415 | The Microtubule-Binding Protein Ensconsin Is an Essential Cofactor of Kinesin-1 |
Q33363125 | The actin-binding protein capulet genetically interacts with the microtubule motor kinesin to maintain neuronal dendrite homeostasis |
Q35830186 | The atypical cadherin flamingo regulates synaptogenesis and helps prevent axonal and synaptic degeneration in Drosophila. |
Q36321480 | The axonal transport of mitochondria. |
Q34616471 | The gene for the intermediate chain subunit of cytoplasmic dynein is essential in Drosophila |
Q33258819 | The genetics of axonal transport and axonal transport disorders |
Q33188203 | The kinesin-associated protein UNC-76 is required for axonal transport in the Drosophila nervous system |
Q24315540 | The mechanism of Ca2+ -dependent regulation of kinesin-mediated mitochondrial motility |
Q37447429 | The neurogenic basic helix-loop-helix transcription factor NeuroD6 concomitantly increases mitochondrial mass and regulates cytoskeletal organization in the early stages of neuronal differentiation |
Q30500390 | The organization of extrinsic neurons and their implications in the functional roles of the mushroom bodies in Drosophila melanogaster Meigen |
Q35020039 | The short coiled-coil domain-containing protein UNC-69 cooperates with UNC-76 to regulate axonal outgrowth and normal presynaptic organization in Caenorhabditis elegans |
Q58081195 | The small G protein Arl8 contributes to lysosomal function and long-range axonal transport in |
Q30418249 | Three routes to suppression of the neurodegenerative phenotypes caused by kinesin heavy chain mutations |
Q30437050 | Tight functional coupling of kinesin-1A and dynein motors in the bidirectional transport of neurofilaments |
Q30842544 | Transport of Drosophila fragile X mental retardation protein-containing ribonucleoprotein granules by kinesin-1 and cytoplasmic dynein. |
Q46869302 | Two kinesins drive anterograde neuropeptide transport. |
Q55383005 | UNC-16/JIP3 and UNC-76/FEZ1 limit the density of mitochondria in C. elegans neurons by maintaining the balance of anterograde and retrograde mitochondrial transport. |
Q24646503 | UNC-51/ATG1 kinase regulates axonal transport by mediating motor-cargo assembly |
Q48092663 | Understanding Miro GTPases: Implications in the Treatment of Neurodegenerative Disorders. |
Q51735877 | Vesicular Axonal Transport is Modified In Vivo by Tau Deletion or Overexpression in Drosophila. |
Q41958111 | Visualization of larval segmental nerves in 3(rd) instar Drosophila larval preparations. |
Q35888349 | Walking motion of an overdamped active particle in a ratchet potential |
Q47070850 | dAcsl, the Drosophila ortholog of acyl-CoA synthetase long-chain family member 3 and 4, inhibits synapse growth by attenuating bone morphogenetic protein signaling via endocytic recycling. |
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