review article | Q7318358 |
scholarly article | Q13442814 |
P2093 | author name string | S Gandy | |
S Petanceska | |||
P2860 | cites work | Apolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer disease | Q22248076 |
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptors | Q24294213 | ||
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's disease | Q24316501 | ||
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells | Q28119154 | ||
Apolipoprotein E: a pathological chaperone protein in patients with cerebral and systemic amyloid | Q28279517 | ||
Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's disease | Q29614374 | ||
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptides | Q32067582 | ||
Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II. | Q33642350 | ||
Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylation | Q33731523 | ||
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivo | Q34063772 | ||
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursor | Q34475374 | ||
Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female rats | Q34564472 | ||
Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunities | Q36061994 | ||
Activated release of membrane-anchored TGF-alpha in the absence of cytosol | Q36232614 | ||
Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptide | Q36578141 | ||
Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein. | Q36749952 | ||
Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor protein | Q36935627 | ||
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursor | Q37265547 | ||
Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer disease | Q40569985 | ||
M1 agonists for the treatment of Alzheimer's disease. Novel properties and clinical update | Q40983072 | ||
Estrogens influence growth, maturation, and amyloid beta-peptide production in neuroblastoma cells and in a beta-APP transfected kidney 293 cell line. | Q41136817 | ||
Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tail | Q41509927 | ||
The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signaling | Q42462551 | ||
Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells. | Q42476656 | ||
Dehydroepiandrosterone augments M1-muscarinic receptor-stimulated amyloid precursor protein secretion in desensitized PC12M1 cells. | Q42515703 | ||
Secretory processing of the Alzheimer amyloid beta/A4 protein precursor is increased by protein phosphorylation | Q43705003 | ||
Estrogen therapy in postmenopausal women: effects on cognitive function and dementia | Q46765861 | ||
Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease. | Q46833795 | ||
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43). | Q48092766 | ||
Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins. | Q48477194 | ||
Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester. | Q48519738 | ||
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition | Q48601482 | ||
Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation. | Q49122782 | ||
Involvement of cell surface glycosyl-phosphatidylinositol-linked aspartyl proteases in alpha-secretase-type cleavage and ectodomain solubilization of human Alzheimer beta-amyloid precursor protein in yeast. | Q52532656 | ||
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein. | Q53200160 | ||
Dehydroepiandrosterone (DHEA) increases production and release of Alzheimer's amyloid precursor protein. | Q53214791 | ||
Neuron loss in APP transgenic mice | Q59060085 | ||
Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactions | Q70478363 | ||
Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the m1 muscarinic receptor to beta-amyloid precursor protein secretion | Q77499756 | ||
A novel, synergistic interaction between 17 beta-estradiol and glutathione in the protection of neurons against beta-amyloid 25-35-induced toxicity in vitro | Q77520422 | ||
An essential role for ectodomain shedding in mammalian development | Q77544828 | ||
Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific manner | Q77781712 | ||
P433 | issue | 1 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | Alzheimer's disease | Q11081 |
P304 | page(s) | 44-52 | |
P577 | publication date | 2000-07-01 | |
P1433 | published in | Biochimica et Biophysica Acta | Q864239 |
P1476 | title | Regulation of Alzheimer beta-amyloid precursor trafficking and metabolism | |
P478 | volume | 1502 |
Q37214528 | A review of imaging agent development |
Q34349174 | Alzheimer's disease: its diagnosis and pathogenesis. |
Q34455106 | Cerebrovascular structure and dementia: new drug targets |
Q28204071 | Changes in Apolipoprotein E Expression in Response to Dietary and Pharmacological Modulation of Cholesterol |
Q28287090 | Cholinergic treatments with emphasis on m1 muscarinic agonists as potential disease-modifying agents for Alzheimer's disease |
Q34311248 | EGCG functions through estrogen receptor‐mediated activation of ADAM10 in the promotion of non‐amyloidogenic processing of APP |
Q36870079 | Environmental and dietary risk factors in Alzheimer's disease |
Q40571948 | GM1 ganglioside regulates the proteolysis of amyloid precursor protein |
Q28588884 | Loss of LR11/SORLA enhances early pathology in a mouse model of amyloidosis: evidence for a proximal role in Alzheimer's disease |
Q34687686 | Neurons bearing presenilins: weapons for defense or suicide? |
Q35544686 | Ovarian steroids regulate gene expression related to DNA repair and neurodegenerative diseases in serotonin neurons of macaques |
Q27001550 | Platelets and Alzheimer's disease: Potential of APP as a biomarker |
Q39850189 | The Associations between a Capsaicin-Rich Diet and Blood Amyloid-β Levels and Cognitive Function |
Q35989365 | blue cheese mutations define a novel, conserved gene involved in progressive neural degeneration. |