Regulation of Alzheimer beta-amyloid precursor trafficking and metabolism

scientific article

Regulation of Alzheimer beta-amyloid precursor trafficking and metabolism is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0925-4439(00)00031-4
P698PubMed publication ID10899430
P5875ResearchGate publication ID246096730

P2093author name stringS Gandy
S Petanceska
P2860cites workApolipoprotein E: high-avidity binding to beta-amyloid and increased frequency of type 4 allele in late-onset familial Alzheimer diseaseQ22248076
Release of Alzheimer amyloid precursor derivatives stimulated by activation of muscarinic acetylcholine receptorsQ24294213
Cloning of a gene bearing missense mutations in early-onset familial Alzheimer's diseaseQ24316501
A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cellsQ28119154
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Secreted amyloid beta-protein similar to that in the senile plaques of Alzheimer's disease is increased in vivo by the presenilin 1 and 2 and APP mutations linked to familial Alzheimer's diseaseQ29614374
Estrogen reduces neuronal generation of Alzheimer beta-amyloid peptidesQ32067582
Phosphorylation of Alzheimer disease amyloid precursor peptide by protein kinase C and Ca2+/calmodulin-dependent protein kinase II.Q33642350
Processing of Alzheimer beta/A4 amyloid precursor protein: modulation by agents that regulate protein phosphorylationQ33731523
Familial Alzheimer's disease-linked presenilin 1 variants elevate Abeta1-42/1-40 ratio in vitro and in vivoQ34063772
Evidence that tumor necrosis factor alpha converting enzyme is involved in regulated alpha-secretase cleavage of the Alzheimer amyloid protein precursorQ34475374
Estradiol increases choline acetyltransferase activity in specific basal forebrain nuclei and projection areas of female ratsQ34564472
Amyloidogenesis in Alzheimer's disease: some possible therapeutic opportunitiesQ36061994
Activated release of membrane-anchored TGF-alpha in the absence of cytosolQ36232614
Protein phosphorylation inhibits production of Alzheimer amyloid beta/A4 peptideQ36578141
Morphologic and biochemical analysis of the intracellular trafficking of the Alzheimer beta/A4 amyloid precursor protein.Q36749952
Protein phosphorylation regulates secretion of Alzheimer beta/A4 amyloid precursor proteinQ36935627
Cholinergic agonists and interleukin 1 regulate processing and secretion of the Alzheimer beta/A4 amyloid protein precursorQ37265547
Processing of Alzheimer A beta-amyloid precursor protein: cell biology, regulation, and role in Alzheimer diseaseQ40569985
M1 agonists for the treatment of Alzheimer's disease. Novel properties and clinical updateQ40983072
Estrogens influence growth, maturation, and amyloid beta-peptide production in neuroblastoma cells and in a beta-APP transfected kidney 293 cell line.Q41136817
Regulated cleavage of Alzheimer beta-amyloid precursor protein in the absence of the cytoplasmic tailQ41509927
The regulation of amyloid precursor protein metabolism by cholinergic mechanisms and neurotrophin receptor signalingQ42462551
Reciprocal regulation of estrogen and NGF receptors by their ligands in PC12 cells.Q42476656
Dehydroepiandrosterone augments M1-muscarinic receptor-stimulated amyloid precursor protein secretion in desensitized PC12M1 cells.Q42515703
Secretory processing of the Alzheimer amyloid beta/A4 protein precursor is increased by protein phosphorylationQ43705003
Estrogen therapy in postmenopausal women: effects on cognitive function and dementiaQ46765861
Increased synaptic sprouting in response to estrogen via an apolipoprotein E-dependent mechanism: implications for Alzheimer's disease.Q46833795
Visualization of A beta 42(43) and A beta 40 in senile plaques with end-specific A beta monoclonals: evidence that an initially deposited species is A beta 42(43).Q48092766
Glial fibrillary acidic protein-apolipoprotein E (apoE) transgenic mice: astrocyte-specific expression and differing biological effects of astrocyte-secreted apoE3 and apoE4 lipoproteins.Q48477194
Turnover of amyloid beta-protein in mouse brain and acute reduction of its level by phorbol ester.Q48519738
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide depositionQ48601482
Sequence of deposition of heterogeneous amyloid beta-peptides and APO E in Down syndrome: implications for initial events in amyloid plaque formation.Q49122782
Involvement of cell surface glycosyl-phosphatidylinositol-linked aspartyl proteases in alpha-secretase-type cleavage and ectodomain solubilization of human Alzheimer beta-amyloid precursor protein in yeast.Q52532656
Regulated formation of Golgi secretory vesicles containing Alzheimer beta-amyloid precursor protein.Q53200160
Dehydroepiandrosterone (DHEA) increases production and release of Alzheimer's amyloid precursor protein.Q53214791
Neuron loss in APP transgenic miceQ59060085
Apolipoprotein E in sporadic Alzheimer's disease: allelic variation and receptor interactionsQ70478363
Mitogen-activated protein kinase-dependent and protein kinase C-dependent pathways link the m1 muscarinic receptor to beta-amyloid precursor protein secretionQ77499756
A novel, synergistic interaction between 17 beta-estradiol and glutathione in the protection of neurons against beta-amyloid 25-35-induced toxicity in vitroQ77520422
An essential role for ectodomain shedding in mammalian developmentQ77544828
Apolipoprotein E promotes the binding and uptake of beta-amyloid into Chinese hamster ovary cells in an isoform-specific mannerQ77781712
P433issue1
P407language of work or nameEnglishQ1860
P921main subjectAlzheimer's diseaseQ11081
P304page(s)44-52
P577publication date2000-07-01
P1433published inBiochimica et Biophysica ActaQ864239
P1476titleRegulation of Alzheimer beta-amyloid precursor trafficking and metabolism
P478volume1502

Reverse relations

cites work (P2860)
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