Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses

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Bad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses is …
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scholarly articleQ13442814
review articleQ7318358

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P819ADS bibcode2000PNAS...97.8829M
P356DOI10.1073/PNAS.97.16.8829
P932PMC publication ID34019
P698PubMed publication ID10922042
P5875ResearchGate publication ID12398011

P2093author name stringJ J Martinez
S J Hultgren
J D Schilling
M A Mulvey
P2860cites workNeutrophil recruitment and resistance to urinary tract infection.Q43553817
E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cellsQ45345430
Bacteriology and ultrastructure of the bladder in patients with urinary tract infections.Q52495940
Survival of FimH-expressing enterobacteria in macrophages relies on glycolipid trafficQ57962356
BACTERIAL VIRULENCE IN URINARY TRACT INFECTIONQ62061199
Macrophage inflammatory protein-2 is required for neutrophil passage across the epithelial barrier of the infected urinary tractQ63363459
Induction and evasion of host defenses by type 1-piliated uropathogenic Escherichia coliQ64449884
Neutrophil activation by nascent FimH subunits of type 1 fimbriae purified from the periplasm of Escherichia coliQ64450454
A comparative study of the desquamation of urothelial cells during gestation and in adults mice following moderate stress or endotoxin treatmentQ70932021
Clinical implications of mast cell-bacteria interactionQ77189215
Genetic analysis of Escherichia coli biofilm formation: roles of flagella, motility, chemotaxis and type I piliQ77472923
Interleukin-6 and disease severity in patients with bacteremic and nonbacteremic febrile urinary tract infectionQ77643471
Caspases: the executioners of apoptosisQ24530218
Type 1 fimbrial expression enhances Escherichia coli virulence for the urinary tractQ24631903
X-ray structure of the FimC-FimH chaperone-adhesin complex from uropathogenic Escherichia coliQ27619358
Prevention of mucosal Escherichia coli infection by FimH-adhesin-based systemic vaccinationQ28235474
Virulence factors in Escherichia coli urinary tract infectionQ28468751
Elevated interleukin-8 levels in the urine of patients with urinary tract infections.Q33619559
Time course and host responses to Escherichia coli urinary tract infection in genetically distinct mouse strains.Q33754925
Development of a long-term ascending urinary tract infection mouse model for antibiotic treatment studiesQ33978522
The mammalian urinary bladder: an accommodating organQ34042600
Interleukin-8 and the neutrophil response to mucosal gram-negative infectionQ34170880
Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cellsQ34173409
Role of IL-6 and its soluble receptor in induction of chemokines and leukocyte recruitment.Q34419957
FimH adhesin of type 1 pili is assembled into a fibrillar tip structure in the EnterobacteriaceaeQ34566388
Escherichia coli induces transuroepithelial neutrophil migration by an intercellular adhesion molecule-1-dependent mechanismQ35444967
Lesions in two Escherichia coli type 1 pilus genes alter pilus number and length without affecting receptor bindingQ36127265
An electron microscopic study of the interaction between vesical epitherlium and E. ColiQ36479701
Interleukin-6 response to deliberate colonization of the human urinary tract with gram-negative bacteria.Q36960257
Endotoxin-induced shedding of viable uroepithelial cells is an antimicrobial defense mechanismQ36996985
Difference in susceptibility to gram-negative urinary tract infection between C3H/HeJ and C3H/HeN miceQ37043190
In vitro binding of type 1-fimbriated Escherichia coli to uroplakins Ia and Ib: relation to urinary tract infectionsQ37358183
Localization of a domain in the FimH adhesin of Escherichia coli type 1 fimbriae capable of receptor recognition and use of a domain-specific antibody to confer protection against experimental urinary tract infectionQ37371765
Uroepithelial cells are part of a mucosal cytokine networkQ39860504
Type 1 pilus-mediated bacterial invasion of bladder epithelial cellsQ39922793
Interleukin-6 response of epithelial cell lines to bacterial stimulation in vitroQ40146112
Pleiotropic defects of IL-6-deficient mice including early hematopoiesis, T and B cell function, and acute phase responses.Q40403937
P fimbriae-dependent, lipopolysaccharide-independent activation of epithelial cytokine responsesQ40935399
Nonfimbrial adhesins of Escherichia coli.Q41191653
Role of the ceramide-signaling pathway in cytokine responses to P-fimbriated Escherichia coliQ41223294
Formation of asymmetric unit membrane during urothelial differentiationQ41292198
Neutrophil receptors for interleukin-8 and related CXC chemokinesQ41623891
Pathogenesis of urinary tract infection. Role of host defensesQ41649426
Diagnosis and treatment of uncomplicated urinary tract infectionQ41649429
The pathogenesis of urinary tract infections associated with Escherichia coli, Staphylococcus saprophyticus and S. epidermidisQ42115905
P433issue16
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
P304page(s)8829-8835
P577publication date2000-08-01
P1433published inProceedings of the National Academy of Sciences of the United States of AmericaQ1146531
P1476titleBad bugs and beleaguered bladders: interplay between uropathogenic Escherichia coli and innate host defenses
P478volume97

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