Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells

scientific article

Identification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/0092-8674(87)90335-7
P698PubMed publication ID3304658
P5875ResearchGate publication ID19850972

P50authorRalph R. IsbergQ88797742
P2093author name stringFalkow S
Voorhis DL
P433issue5
P407language of work or nameEnglishQ1860
P921main subjectbacteriaQ10876
P304page(s)769-778
P577publication date1987-08-01
P1433published inCellQ655814
P1476titleIdentification of invasin: a protein that allows enteric bacteria to penetrate cultured mammalian cells
P478volume50

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cites work (P2860)
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Q41444281Distribution of virF/lcrF-positive Yersinia pseudotuberculosis serotype O:3 at farm level.
Q45345430E-cadherin is the receptor for internalin, a surface protein required for entry of L. monocytogenes into epithelial cells
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Q35100130Entry of genital Chlamydia trachomatis into polarized human epithelial cells
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Q40777565Environmental control of invasin expression in Yersinia pseudotuberculosis is mediated by regulation of RovA, a transcriptional activator of the SlyA/Hor family
Q34033868Environmental regulation and virulence attributes of the Ysa type III secretion system of Yersinia enterocolitica biovar 1B.
Q33750433Environmental regulation of Salmonella typhi invasion-defective mutants
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Q37063357Escherichia coli expressing a Neisseria gonorrhoeae opacity-associated outer membrane protein invade human cervical and endometrial epithelial cell lines
Q35451232Escherichia coli invasion of brain microvascular endothelial cells in vitro and in vivo: molecular cloning and characterization of invasion gene ibe10
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Q44534416Evidence for pore-forming ability by Legionella pneumophila
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Q35362454Expression during host infection and localization of Yersinia pestis autotransporter proteins
Q36984314Expression of Salmonella typhimurium genes required for invasion is regulated by changes in DNA supercoiling
Q30642177Expression of random peptide fused to invasin on bacterial cell surface for selection of cell-targeting peptides
Q36946825Expression of receptors for enterotoxigenic Escherichia coli during enterocytic differentiation of human polarized intestinal epithelial cells in culture
Q35780704Factors affecting invasion of HT-29 and HEp-2 epithelial cells by organisms of the Mycobacterium avium complex
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Q24548752Heterologously expressed Staphylococcus aureus fibronectin-binding proteins are sufficient for invasion of host cells
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Q36957334Human platelet aggregation by Yersinia pseudotuberculosis is mediated by invasin
Q35885856Hypoxia Decreases Invasin-Mediated Yersinia enterocolitica Internalization into Caco-2 Cells
Q41477415Identification and characterization of BipA, a Bordetella Bvg-intermediate phase protein
Q46076466Identification and characterization of TnphoA mutants of Salmonella that are unable to pass through a polarized MDCK epithelial cell monolayer
Q30964813Identification and characterization of Yersinia enterocolitica genes induced during systemic infection
Q33585993Identification and characterization of small-molecule inhibitors of Yop translocation in Yersinia pseudotuberculosis
Q39942598Identification and localization of major stage-specific polypeptides of infectious Holospora obtusa with monoclonal antibodies
Q36983530Identification of Campylobacter jejuni surface proteins that bind to Eucaryotic cells in vitro
Q34372298Identification of MrtAB, an ABC transporter specifically required for Yersinia pseudotuberculosis to colonize the mesenteric lymph nodes
Q40425753Identification of an extracellular protein of Listeria monocytogenes possibly involved in intracellular uptake by mammalian cells
Q34007106Identification of attenuated Yersinia pseudotuberculosis strains and characterization of an orogastric infection in BALB/c mice on day 5 postinfection by signature-tagged mutagenesis
Q31815750Identification of exported bacterial proteins via gene fusions to Yersinia pseudotuberculosis invasin
Q35576276Identification of mycobacterium tuberculosis DNA sequences encoding exported proteins by using phoA gene fusions
Q38340751Identification of the integrin binding domain of the Yersinia pseudotuberculosis invasin protein
Q35774822Immunization with live aroA recombinant Salmonella typhimurium producing invasin inhibits intestinal translocation of Yersinia pseudotuberculosis
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Q41503633Influence of lactoferrin on the entry process of Escherichia coli HB101 (pRI203) in HeLa cells
Q41448131Influence of the Cpx extracytoplasmic-stress-responsive pathway on Yersinia sp.-eukaryotic cell contact
Q47913773Inhibition of Cytokine-Induced Fractalkine Production by Bacterial Invasion of Human-Dermal Fibroblasts
Q36955621Inhibition of ROCK activity allows InlF-mediated invasion and increased virulence of Listeria monocytogenes
Q33767630Inhibition of Salmonella typhimurium invasion by host cell expression of secreted bacterial invasion proteins
Q36998408Inhibition of phagocytosis in Yersinia pseudotuberculosis: a virulence plasmid-encoded ability involving the Yop2b protein
Q39654166Interaction of an uuter membrane protein of enterotoxigenic Escherichia coli with cell surface heparan sulfate proteoglycans.
Q41483876Interaction of microorganisms, epithelium, and lymphoid cells of the mucosa-associated lymphoid tissue
Q64102323Interacts With SIGNR1 (CD209b) for Promoting Host Dissemination and Infection
Q24672095Internalin of Listeria monocytogenes with an intact leucine-rich repeat region is sufficient to promote internalization
Q37647153Intestinal villous M cells: an antigen entry site in the mucosal epithelium
Q43580146Intimin from Shiga toxin-producing Escherichia coli and its isolated C-terminal domain exhibit different binding properties for Tir and a eukaryotic surface receptor
Q33748933Intracellular Staphylococcus aureus escapes the endosome and induces apoptosis in epithelial cells.
Q36952928Invasin expression in Yersinia pseudotuberculosis
Q43519258Invasin of Edwardsiella tarda is essential for its haemolytic activity, biofilm formation and virulence towards fish
Q35465426Invasin production by Yersinia pestis is abolished by insertion of an IS200-like element within the inv gene.
Q35553593Invasin-dependent and invasin-independent pathways for translocation of Yersinia pseudotuberculosis across the Peyer's patch intestinal epithelium
Q28486635Invasion activity of a Mycobacterium tuberculosis peptide presented by the Escherichia coli AIDA autotransporter
Q36976906Invasion and replication of Salmonella typhimurium in animal cells.
Q73087341Investigation of mechanisms involved in phagocytosis of Legionella pneumophila by human cells
Q34392887Involvement of M cells in the bacterial invasion of Peyer's patches: a common mechanism shared by Yersinia enterocolitica and other enteroinvasive bacteria
Q35823997Kistrin, an integrin antagonist, blocks endocytosis of fibrinogen into guinea pig megakaryocyte and platelet alpha-granules
Q36928326Lack of antibody response to invasin in humans with yersiniosis
Q34378895Lactobacillus acidophilus LA 1 binds to cultured human intestinal cell lines and inhibits cell attachment and cell invasion by enterovirulent bacteria
Q34019886Lectin-mediated mucosal delivery of drugs and microparticles
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Q25257684Listeria monocytogenes invades the epithelial junctions at sites of cell extrusion
Q39538602Living in stools is not as dumb as you think
Q33751827M-cell surface beta1 integrin expression and invasin-mediated targeting of Yersinia pseudotuberculosis to mouse Peyer's patch M cells
Q21146381Major structural differences and novel potential virulence mechanisms from the genomes of multiple campylobacter species
Q38759213Mammalian cell adhesion functions and cellular penetration of enteropathogenic Yersinia species
Q26742013Manipulation of host membranes by the bacterial pathogens Listeria, Francisella, Shigella and Yersinia
Q36987647Mapping and topographic localization of epitopes of the Yersinia pseudotuberculosis invasin protein
Q39291680Mechanism of H. pylori intracellular entry: an in vitro study
Q41243986Migration of Salmonella typhi through intestinal epithelial monolayers: an in vitro study
Q41489386Models of invasion of enteric and periodontal pathogens into epithelial cells: a comparative analysis
Q41504980Modulation of leukotriene generation by invasive bacteria
Q36113628Molecular and functional characterization of the Salmonella invasion gene invA: homology of InvA to members of a new protein family
Q34022933Molecular basis of pathogenicity in Blastomyces dermatitidis: the importance of adhesion
Q33214728Molecular cloning of epithelial cell invasion determinants from enterotoxigenic Escherichia coli
Q38360033Mutations in the cytoplasmic domain of the integrin beta1 chain indicate a role for endocytosis factors in bacterial internalization
Q35557550N-glycosylated proteins are involved in efficient internalization of Klebsiella pneumoniae by cultured human epithelial cells
Q77318475Naked DNA dons new clothes
Q36979885Nonpathogenic isolates of Yersinia enterocolitica do not contain functional inv-homologous sequences
Q36122200Nonpolar mutagenesis of the ipa genes defines IpaB, IpaC, and IpaD as effectors of Shigella flexneri entry into epithelial cells
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Q24673497Nucleotide sequence of the Yersinia enterocolitica ail gene and characterization of the Ail protein product
Q41458677Observation of the intracellular behavior of recombinant Yersinia pseudotuberculosis invasin protein
Q36724533OmpA-mediated rickettsial adherence to and invasion of human endothelial cells is dependent upon interaction with α2β1 integrin
Q81504869Opinion: Cell entry machines: a common theme in nature?
Q39734485PCR detection of virulence genes in Yersinia enterocolitica and Yersinia pseudotuberculosis and investigation of virulence gene distribution
Q41123356Pasteurella multocida enters polarized epithelial cells by interacting with host F-actin
Q35923564Pathogen-induced actin filament rearrangement in infectious diseases.
Q37871945Pathogenesis of Brucella
Q35456987Pathogenesis of defined invasion mutants of Yersinia enterocolitica in a BALB/c mouse model of infection
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Q41080846Phase variation of the opacity outer membrane protein controls invasion by Neisseria gonorrhoeae into human epithelial cells
Q24672690Physiological osmotic induction of Leptospira interrogans adhesion: LigA and LigB bind extracellular matrix proteins and fibrinogen
Q36574211Potential virulence factors of Proteus bacilli.
Q36777144Preclinical evaluation of VAX-IP, a novel bacterial minicell-based biopharmaceutical for nonmuscle invasive bladder cancer
Q35708412Proliferation behavior of E. coli in a three-dimensional in vitro tumor model
Q41982319Prospects for the use of artificial chromosomes and minichromosome-like episomes in gene therapy.
Q39571884Purification of the inlB gene product of Listeria monocytogenes and demonstration of its biological activity
Q37713402Putative Inv is essential for basolateral invasion of Caco-2 cells and acts synergistically with OmpA to affect in vitro and in vivo virulence of Cronobacter sakazakii ATCC 29544.
Q44038716Quantitative insights into actin rearrangements and bacterial target site selection from Salmonella Typhimurium infection of micropatterned cells
Q24799086Quinine sulfate and bacterial invasion
Q41497818RAPD analysis of Yersinia enterocolitica
Q34257557Rapid translocation of polarized MDCK cell monolayers by Leptospira interrogans, an invasive but nonintracellular pathogen
Q41454449Recombinant Escherichia coli expressing invasin targets the Peyer's patches: the basis for a bacterial formulation for oral vaccination
Q28300037Reevaluation of the virulence phenotype of the inv yadA double mutants of Yersinia pseudotuberculosis
Q34435364Regulation of the Ysa type III secretion system of Yersinia enterocolitica by YsaE/SycB and YsrS/YsrR
Q33701519Role of fibronectin-binding MSCRAMMs in bacterial adherence and entry into mammalian cells
Q41502444Ruffles induced by Salmonella and other stimuli direct macropinocytosis of bacteria
Q41485965SWIM analysis allows rapid identification of residues involved in invasin-mediated bacterial uptake
Q40375812Salmonella invasion of nonphagocytic cells induces formation of macropinosomes in the host cell
Q30480354Salmonella trafficking is defined by continuous dynamic interactions with the endolysosomal system.
Q27471608Selection of peptide entry motifs by bacterial surface display
Q36455856Self-compartmentalized bacterial proteases and pathogenesis
Q37597407Sensitive and specific detection of Yersinia pseudotuberculosis by loop-mediated isothermal amplification
Q92942256Serotype-specific evolutionary patterns of antimicrobial-resistant Salmonella enterica
Q34525784Short hairpin RNA-expressing bacteria elicit RNA interference in mammals
Q24644554Signals, regulatory networks, and materials that build and break bacterial biofilms
Q38302074Site-directed mutagenesis of intimin alpha modulates intimin-mediated tissue tropism and host specificity
Q35477717Sporadic invasion of cultured epithelial cells by Haemophilus influenzae type b
Q58616115Stress-induced host membrane remodeling protects from infection by non-motile bacterial pathogens
Q27727218Structural basis for Myf and Psa fimbriae-mediated tropism of pathogenic strains of Yersinia for host tissues
Q24685613Structural basis for recognition of the translocated intimin receptor (Tir) by intimin from enteropathogenic Escherichia coli
Q38859200Structure of the Y. pseudotuberculosis adhesin InvasinE.
Q36263415Structure, Function, and Assembly of Adhesive Organelles by Uropathogenic Bacteria
Q33775586Sublethal doses of anthrax lethal toxin on the suppression of macrophage phagocytosis
Q36375507Suppression of T and B lymphocyte activation by a Yersinia pseudotuberculosis virulence factor, yopH
Q41564068Surface-associated, PrfA-regulated proteins of Listeria monocytogenes synthesized under stress conditions
Q36574864Temperature regulation of the hemin storage (Hms+) phenotype of Yersinia pestis is posttranscriptional
Q37568967Tetracycline resistance in Chlamydia suis mediated by genomic islands inserted into the chlamydial inv-like gene
Q33729857The C-terminal variable domain of LigB from Leptospira mediates binding to fibronectin
Q36437361The Chlamydia outer membrane protein OmcB is required for adhesion and exhibits biovar-specific differences in glycosaminoglycan binding
Q89170428The Quorum Sensing System of Yersinia enterocolitica 8081 Regulates Swimming Motility, Host Cell Attachment, and Virulence Plasmid Maintenance
Q41481125The Tir-binding region of enterohaemorrhagic Escherichia coli intimin is sufficient to trigger actin condensation after bacterial-induced host cell signalling
Q39656163The YadA protein of Yersinia pseudotuberculosis mediates high-efficiency uptake into human cells under environmental conditions in which invasin is repressed
Q36257101The Yersinia enterocolitica inv gene product is an outer membrane protein that shares epitopes with Yersinia pseudotuberculosis invasin
Q36144953The Yersinia pestis V antigen is a regulatory protein necessary for Ca2(+)-dependent growth and maximal expression of low-Ca2+ response virulence genes
Q36232127The Yersinia tyrosine phosphatase: specificity of a bacterial virulence determinant for phosphoproteins in the J774A.1 macrophage
Q31052468The Yersinia yop regulon
Q33616743The ability of Salmonella to enter mammalian cells is affected by bacterial growth state
Q35088783The ail locus is found uniquely in Yersinia enterocolitica serotypes commonly associated with disease
Q42016873The carbohydrate ligands on the host embryo mediate intercellular migration of the parasitic wasp embryo
Q41490672The cell-binding domain of intimin from enteropathogenic Escherichia coli binds to beta1 integrins
Q34284486The chlamydial invasin-like protein gene conundrum
Q33296886The complete genome sequence of Yersinia pseudotuberculosis IP31758, the causative agent of Far East scarlet-like fever
Q34215777The cytotoxic protein YopE of Yersinia obstructs the primary host defence
Q36989598The eae gene of enteropathogenic Escherichia coli encodes a 94-kilodalton membrane protein, the expression of which is influenced by the EAF plasmid
Q34334242The established intimin receptor Tir and the putative eucaryotic intimin receptors nucleolin and beta1 integrin localize at or near the site of enterohemorrhagic Escherichia coli O157:H7 adherence to enterocytes in vivo
Q36984651The gene coding for protein p60 of Listeria monocytogenes and its use as a specific probe for Listeria monocytogenes
Q41484749The identification of exported proteins with gene fusions to invasin
Q36366266The inlAB locus mediates the entry of Listeria monocytogenes into hepatocytes in vivo
Q36951060The integrin-binding domain of invasin is sufficient to allow bacterial entry into mammalian cells
Q36530747The invasin protein of Yersinia enterocolitica: internalization of invasin-bearing bacteria by eukaryotic cells is associated with reorganization of the cytoskeleton
Q38318002The invasin protein of Yersinia spp. provides co-stimulatory activity to human T cells through interaction with beta 1 integrins
Q41495118The mechanism of phagocytic uptake promoted by invasin-integrin interaction
Q28776876The nasFEDCBA operon for nitrate and nitrite assimilation in Klebsiella pneumoniae M5al
Q27318344The natural antimicrobial carvacrol inhibits Campylobacter jejuni motility and infection of epithelial cells
Q41441562The polybasic region of Rac1 modulates bacterial uptake independently of self-association and membrane targeting
Q47918452The porin OmpC of Salmonella typhimurium mediates adherence to macrophages
Q38574548The revival of interest in mechanisms of bacterial pathogenicity
Q34102030The superantigenic toxin of Yersinia pseudotuberculosis: a novel virulence factor?
Q35953393The virulence factor ychO has a pleiotropic action in an Avian Pathogenic Escherichia coli (APEC) strain
Q28290675The virulence plasmid of Yersinia, an antihost genome
Q33886250Towards a synthetic chloroplast
Q33848915TransKingdom RNA interference: a bacterial approach to challenges in RNAi therapy and delivery
Q47215199Transcription control engineering and applications in synthetic biology.
Q41434055Transcriptional activation of the tad type IVb pilus operon by PypB in Yersinia enterocolitica
Q34384351Transcytosis of nanoparticle and dendrimer delivery systems: evolving vistas
Q37600906Transkingdom RNA interference (tkRNAi) as a new delivery tool for therapeutic RNA.
Q40826522Translocation of Yersinia entrocolitica across reconstituted intestinal epithelial monolayers is triggered by Yersinia invasin binding to beta1 integrins apically expressed on M-like cells
Q36886250Treponema pallidum Lipoprotein TP0435 Expressed in Borrelia burgdorferi Produces Multiple Surface/Periplasmic Isoforms and mediates Adherence.
Q35499213Truncated enterohemorrhagic Escherichia coli (EHEC) O157:H7 intimin (EaeA) fusion proteins promote adherence of EHEC strains to HEp-2 cells.
Q39922793Type 1 pilus-mediated bacterial invasion of bladder epithelial cells
Q92862822Type V Secretion Systems: An Overview of Passenger Domain Functions
Q40146789Tyrosine protein kinase inhibitors block invasin-promoted bacterial uptake by epithelial cells
Q39829491Unmasking of intestinal epithelial lateral membrane beta1 integrin consequent to transepithelial neutrophil migration in vitro facilitates inv-mediated invasion by Yersinia pseudotuberculosis
Q35547836Urease is not involved in the virulence of Yersinia pseudotuberculosis in mice
Q37029864Uropathogenic Escherichia coli invades host cells via an HDAC6-modulated microtubule-dependent pathway.
Q41486623Utilizing bacterial mechanisms of epithelial cell entry: invasin-induced oral uptake of latex nanoparticles
Q40872003Variable opacity (Opa) outer membrane proteins account for the cell tropisms displayed by Neisseria gonorrhoeae for human leukocytes and epithelial cells
Q24815447Viral promoters can initiate expression of toxin genes introduced into Escherichia coli
Q35766458Virulent strain associated outer membrane proteins of Borrelia burgdorferi
Q28250707YadA mediates specific binding of enteropathogenic Yersinia enterocolitica to human intestinal submucosa
Q30251607Yersinia adhesins: An arsenal for infection.
Q37548060Yersinia enterocolitica inhibits Salmonella enterica serovar Typhimurium and Listeria monocytogenes cellular uptake
Q33256106Yersinia has a tropism for B and T cell zones of lymph nodes that is independent of the type III secretion system
Q26994659Yersinia infection tools-characterization of structure and function of adhesins
Q36159264Yersinia pestis Ail: multiple roles of a single protein
Q36986872Yersinia pestis pH 6 antigen: genetic, biochemical, and virulence characterization of a protein involved in the pathogenesis of bubonic plague
Q37412102Yersinia pestis: mechanisms of entry into and resistance to the host cell
Q57803089Yersinia pseudotuberculosis Exploits CD209 Receptors for Promoting Host Dissemination and Infection.
Q30441346Yersinia pseudotuberculosis adhesins regulate tissue-specific colonization and immune cell localization in a mouse model of systemic infection
Q41441863Yersinia pseudotuberculosis induces transcytosis of nanoparticles across human intestinal villus epithelium via invasin-dependent macropinocytosis
Q100739332Yersinia pseudotuberculosis: Cultivation, Storage, and Methods for Introducing DNA
Q26747057Yersinia virulence factors - a sophisticated arsenal for combating host defences
Q35105786YopM inhibits platelet aggregation and is necessary for virulence of Yersinia pestis in mice
Q40268028Yops of Yersinia spp. pathogenic for humans.
Q39510663beta1-chain integrins are not essential for intimin-mediated host cell attachment and enteropathogenic Escherichia coli-induced actin condensation
Q64124362interacts with CD209 receptors to promote host dissemination and infection

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