Role of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptor

scientific article

Role of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptor is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1152/AJPENDO.00067.2010
P932PMC publication ID2904048
P698PubMed publication ID20407008
P5875ResearchGate publication ID43226942

P2093author name stringQuan Chen
Laurence J Miller
Maoqing Dong
P2860cites workN-linked glycosylation of the human bradykinin B2 receptor is required for optimal cell-surface expression and couplingQ40587374
N-glycosylation of CRF receptor type 1 is important for its ligand-specific interactionQ40775594
Identification of the sites of N-linked glycosylation on the human calcium receptor and assessment of their role in cell surface expression and signal transductionQ40988614
Relationship between native and recombinant cholecystokinin receptors: role of differential glycosylationQ41179224
Multiple extracellular loop domains contribute critical determinants for agonist binding and activation of the secretin receptorQ41190802
Role of N-glycan-dependent quality control in the cell-surface expression of the AT1 receptorQ46858556
Intracellularly located misfolded glycoprotein hormone receptors associate with different chaperone proteins than their cognate wild-type receptorsQ47709942
Role of glycosylation in expression and function of the human parathyroid hormone/parathyroid hormone-related protein receptorQ71878584
Structure and function in rhodopsin. Requirements of a specific structure for the intradiscal domainQ72108005
Influence of the N-linked oligosaccharides on the biosynthesis, intracellular routing, and function of the human asialoglycoprotein receptorQ72389915
Glycosylation of the GLP-1 receptor is a prerequisite for regular receptor functionQ72745906
Glycosylation of the calcitonin receptor-like receptor at Asn(60) or Asn(112) is important for cell surface expressionQ73303534
Glycosylation is important for binding to human calcitonin receptorsQ74456788
GlycobiologyQ22255657
Molecular basis of association of receptor activity-modifying protein 3 with the family B G protein-coupled secretin receptorQ24644625
Mechanisms of action of glucagon-like peptide 1 in the pancreasQ24683764
Crystal structure of the ligand-bound glucagon-like peptide-1 receptor extracellular domainQ27649890
Crystal Structure of Glucagon-like Peptide-1 in Complex with the Extracellular Domain of the Glucagon-like Peptide-1 ReceptorQ27657999
Role of N-linked glycosylation on the function and expression of the human secretin receptorQ28146073
LIGAND: A versatile computerized approach for characterization of ligand-binding systemsQ29547346
Molecular basis of glucagon-like peptide 1 docking to its intact receptor studied with carboxyl-terminal photolabile probesQ33553466
Glycosylation of G-protein-coupled receptors for hormones central to normal reproductive functioning: its occurrence and role.Q33721703
Glycosylation of human CRLR at Asn123 is required for ligand binding and signalingQ33949760
Mutagenesis of N-glycosylation sites in the human vasoactive intestinal peptide 1 receptor. Evidence that asparagine 58 or 69 is crucial for correct delivery of the receptor to plasma membraneQ34380939
Insights into the structural basis of endogenous agonist activation of family B G protein-coupled receptorsQ36710162
Intrinsic photoaffinity labeling of native and recombinant rat pancreatic secretin receptorsQ36754122
Pattern of intra-family hetero-oligomerization involving the G-protein-coupled secretin receptorQ37430299
Role of asparagine-linked oligosaccharides in the function of the rat PTH/PTHrP receptorQ38311877
Role of N-glycosylation in the expression and functional properties of human AT1 receptorQ38323158
Role of the signal peptide in the synthesis and processing of the glucagon-like peptide-1 receptorQ39764872
P433issue1
P921main subjectglycosylationQ898365
P304page(s)E62-8
P577publication date2010-04-20
P1433published inAmerican Journal of Physiology - Endocrinology and MetabolismQ15765671
P1476titleRole of N-linked glycosylation in biosynthesis, trafficking, and function of the human glucagon-like peptide 1 receptor
P478volume299

Reverse relations

cites work (P2860)
Q36396618A Novel Interacting Protein SERP1 Regulates the N-Linked Glycosylation and Function of GLP-1 Receptor in the Liver.
Q35138670A novel humanized GLP-1 receptor model enables both affinity purification and Cre-LoxP deletion of the receptor
Q92726723Agonist-induced membrane nanodomain clustering drives GLP-1 receptor responses in pancreatic beta cells
Q89610398Calcitonin Receptor N-Glycosylation Enhances Peptide Hormone Affinity by Controlling Receptor Dynamics
Q33615669Genetically encoded photocross-linkers determine the biological binding site of exendin-4 peptide in the N-terminal domain of the intact human glucagon-like peptide-1 receptor (GLP-1R)
Q28067465Glucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic Successes
Q35129668Improved functional expression of human cardiac kv1.5 channels and trafficking-defective mutants by low temperature treatment
Q46350132N-Glycosylation of Asparagine 130 in the Extracellular Domain of the Human Calcitonin Receptor Significantly Increases Peptide Hormone Affinity
Q36851726N-linked glycosylation is required for transferrin-induced stabilization of transferrin receptor 2, but not for transferrin binding or trafficking to the cell surface
Q41762728Optimized protocol for expression and purification of membrane-bound PglB, a bacterial oligosaccharyl transferase.
Q33786810Recombinant expression, purification, and functional characterisation of connective tissue growth factor and nephroblastoma-overexpressed protein
Q35660100The atypical N-glycosylation motif, Asn-Cys-Cys, in human GPR109A is required for normal cell surface expression and intracellular signaling
Q39265988The human cytomegalovirus chemokine receptor homolog encoded by US27.
Q34554745The putative signal peptide of glucagon-like peptide-1 receptor is not required for receptor synthesis but promotes receptor expression
Q43167212The regions within the N-terminus critical for human glucagon like peptide-1 receptor (hGLP-1R) cell surface expression
Q37939244The structure and function of the glucagon-like peptide-1 receptor and its ligands

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