review article | Q7318358 |
scholarly article | Q13442814 |
P356 | DOI | 10.1002/1097-0029(20000815)50:4<316::AID-JEMT11>3.0.CO;2-E |
P698 | PubMed publication ID | 10936886 |
P2093 | author name string | Cole GM | |
Ard MD | |||
P2860 | cites work | RAGE and amyloid-beta peptide neurotoxicity in Alzheimer's disease | Q24314906 |
Protective effect of apolipoprotein E type 2 allele for late onset Alzheimer disease | Q28238269 | ||
Identification of scavenger receptor SR-BI as a high density lipoprotein receptor | Q28273182 | ||
Characterization of the binding of amyloid-beta peptide to cell culture-derived native apolipoprotein E2, E3, and E4 isoforms and to isoforms from human plasma | Q28771760 | ||
Reactive microglia express class I and class II major histocompatibility complex antigens in Alzheimer's disease | Q48932229 | ||
Microglial cells internalize aggregates of the Alzheimer's disease amyloid beta-protein via a scavenger receptor | Q48933977 | ||
Abeta-peptide length and apolipoprotein E genotype in Alzheimer's disease | Q49106878 | ||
Water-soluble Abeta (N-40, N-42) oligomers in normal and Alzheimer disease brains | Q49112901 | ||
Apolipoprotein E ε4 allele is associated with deposition of amyloid β-protein following head injury | Q53200531 | ||
The lack of accumulation of senile plaques or amyloid burden in Alzheimer's disease suggests a dynamic balance between amyloid deposition and resolution. | Q53207598 | ||
Native complex formation between apolipoprotein E isoforms and the Alzheimer's disease peptide A beta. | Q53212012 | ||
Scavenging of Alzheimer's amyloid beta-protein by microglia in culture. | Q53213552 | ||
Slow degradation of aggregates of the Alzheimer's disease amyloid beta-protein by microglial cells. | Q53220157 | ||
Uptake, degradation, and release of fibrillar and soluble forms of Alzheimer's amyloid beta-peptide by microglial cells. | Q53231151 | ||
Multiple, diverse senile plaque-associated proteins are ligands of an apolipoprotein E receptor, the alpha 2-macroglobulin receptor/low-density-lipoprotein receptor-related protein. | Q53310930 | ||
Apolipoprotein E epsilon 4 allele distributions in late-onset Alzheimer's disease and in other amyloid-forming diseases. | Q53316390 | ||
Activation of phospholipase A2 by amyloid beta-peptides in vitro. | Q53321615 | ||
Preferential deposition of amyloid beta protein (Abeta) in the form Abeta40 in Alzheimer's disease is associated with a gene dosage effect of the apolipoprotein E E4 allele. | Q53325111 | ||
Solvation Effects on the Conformational Behaviour of Gellan and Calcium Ion Binding to Gellan Double Helices | Q57018432 | ||
Amyloid-associated proteins α1-antichymotrypsin and apolipoprotein E promote assembly of Alzheimer β-protein into filaments | Q59053832 | ||
Apolipoprotein E: binding to soluble Alzheimer's beta-amyloid | Q70687889 | ||
Biochemical characterization of Alzheimer's soluble amyloid beta protein in human cerebrospinal fluid: association with high density lipoproteins | Q71209926 | ||
Amyloid beta-peptide is transported on lipoproteins and albumin in human plasma | Q71860042 | ||
Amyloid beta binding proteins in vitro and in normal human cerebrospinal fluid | Q72021497 | ||
Characterization of subpopulations of lipoprotein particles isolated from human cerebrospinal fluid | Q72109694 | ||
Purification of apolipoprotein E attenuates isoform-specific binding to beta-amyloid | Q72167723 | ||
Role of HDL apolipoprotein E in cellular cholesterol efflux: studies in apo E knockout transgenic mice | Q72362838 | ||
The soluble form of Alzheimer's amyloid beta protein is complexed to high density lipoprotein 3 and very high density lipoprotein in normal human plasma | Q72362862 | ||
Upregulation of the macrophage scavenger receptor in response to different forms of injury in the CNS | Q72469240 | ||
Structure and functions of human cerebrospinal fluid lipoproteins from individuals of different APOE genotypes | Q74137894 | ||
Scavenger receptor family proteins: roles for atherosclerosis, host defence and disorders of the central nervous system | Q77119965 | ||
Immunization with amyloid-beta attenuates Alzheimer-disease-like pathology in the PDAPP mouse | Q29619237 | ||
Interaction of apolipoprotein J-amyloid beta-peptide complex with low density lipoprotein receptor-related protein-2/megalin. A mechanism to prevent pathological accumulation of amyloid beta-peptide | Q29977749 | ||
Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease. | Q31949934 | ||
Monoclonal antibodies inhibit in vitro fibrillar aggregation of the Alzheimer beta-amyloid peptide | Q33630090 | ||
Correlation between elevated levels of amyloid beta-peptide in the brain and cognitive decline | Q33895797 | ||
Apolipoprotein E associates with beta amyloid peptide of Alzheimer's disease to form novel monofibrils. Isoform apoE4 associates more efficiently than apoE3 | Q34229659 | ||
Abnormal content of n-6 and n-3 long-chain unsaturated fatty acids in the phosphoglycerides and cholesterol esters of parahippocampal cortex from Alzheimer's disease patients and its relationship to acetyl CoA content | Q34470129 | ||
Abnormal in vivo metabolism of apolipoprotein E4 in humans | Q34539465 | ||
Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease | Q34662682 | ||
Cholesterol depletion inhibits the generation of beta-amyloid in hippocampal neurons | Q34663462 | ||
Apolipoprotein E is a kinetic but not a thermodynamic inhibitor of amyloid formation: implications for the pathogenesis and treatment of Alzheimer disease | Q34729047 | ||
Transthyretin sequesters amyloid beta protein and prevents amyloid formation | Q35700645 | ||
Appearance of sodium dodecyl sulfate-stable amyloid beta-protein (Abeta) dimer in the cortex during aging | Q35754595 | ||
Sequestration of acetylated LDL and cholesterol crystals by human monocyte-derived macrophages | Q36235266 | ||
Increased amyloid beta-peptide deposition in cerebral cortex as a consequence of apolipoprotein E genotype in late-onset Alzheimer disease | Q36604545 | ||
Amyloid beta peptide alters intracellular vesicle trafficking and cholesterol homeostasis | Q36650009 | ||
Distribution of apolipoprotein E in senile plaques in brains with Alzheimer's disease: investigation with the confocal laser scan microscope | Q36853246 | ||
Apolipoprotein E carboxyl-terminal fragments are complexed to amyloids A and L. Implications for amyloidogenesis and Alzheimer's disease | Q40682439 | ||
Expression of human apolipoprotein E reduces amyloid-beta deposition in a mouse model of Alzheimer's disease | Q40849918 | ||
Microglia and cytokines in neurological disease, with special reference to AIDS and Alzheimer's disease | Q40870408 | ||
Apolipoprotein E. Structure, function, and possible roles in Alzheimer's disease | Q40983052 | ||
Effect of chloroquine and leupeptin on intracellular accumulation of amyloid-beta (A beta) 1-42 peptide in a murine N9 microglial cell line | Q40997357 | ||
Immunohistochemical evidence for a macrophage scavenger receptor in Mato cells and reactive microglia of ischemia and Alzheimer's disease | Q41042733 | ||
Interaction of nascent ApoE2, ApoE3, and ApoE4 isoforms expressed in mammalian cells with amyloid peptide beta (1-40). Relevance to Alzheimer's disease. | Q41092801 | ||
Alzheimer's soluble amyloid beta protein is secreted by HepG2 cells as an apolipoprotein | Q41111434 | ||
Multiple inhibitory effects of Alzheimer's peptide Abeta1-40 on lipid biosynthesis in cultured human HepG2 cells | Q41157633 | ||
Scavenger receptor-mediated adhesion of microglia to beta-amyloid fibrils | Q41173971 | ||
Cell surface proteoglycans modulate net synthesis and secretion of macrophage apolipoprotein E. | Q41192692 | ||
Cholesterol modulates alpha-secretase cleavage of amyloid precursor protein | Q41226800 | ||
Amyloid beta protein (A beta) removal by neuroglial cells in culture | Q41300362 | ||
Fibrillogenesis in Alzheimer's disease of amyloid beta peptides and apolipoprotein E. | Q41664894 | ||
Apolipoprotein J and Alzheimer's amyloid beta solubility | Q42160133 | ||
The cerebrospinal-fluid soluble form of Alzheimer's amyloid beta is complexed to SP-40,40 (apolipoprotein J), an inhibitor of the complement membrane-attack complex | Q42161240 | ||
Loss of endosomal/lysosomal membrane impermeability is an early event in amyloid Abeta1-42 pathogenesis | Q46238580 | ||
Brain uptake of circulating apolipoproteins J and E complexed to Alzheimer's amyloid beta | Q46256650 | ||
Seeding of A beta fibril formation is inhibited by all three isotypes of apolipoprotein E. | Q46722154 | ||
Confirmation of an association between a polymorphism in exon 3 of the low-density lipoprotein receptor-related protein gene and Alzheimer's disease | Q47951822 | ||
Soluble amyloid beta-protein is a marker of Alzheimer amyloid in brain but not in cerebrospinal fluid | Q48122531 | ||
The levels of soluble versus insoluble brain Abeta distinguish Alzheimer's disease from normal and pathologic aging | Q48156883 | ||
Microglia and Alzheimer's disease | Q48301324 | ||
Amyloid beta-peptide induces apoptosis-related events in synapses and dendrites | Q48384019 | ||
Apolipoprotein B immunoreactivity in senile plaque and vascular amyloids and neurofibrillary tangles in the brains of patients with Alzheimer's disease | Q48550324 | ||
Ultrastructure of the microglia that phagocytose amyloid and the microglia that produce beta-amyloid fibrils | Q48586335 | ||
Detection of apolipoprotein E/dimeric soluble amyloid beta complexes in Alzheimer's disease brain supernatants | Q48586395 | ||
Lack of apolipoprotein E dramatically reduces amyloid beta-peptide deposition | Q48601482 | ||
Deposition of amyloid beta protein (A beta) subtypes [A beta 40 and A beta 42(43)] in canine senile plaques and cerebral amyloid angiopathy | Q48612911 | ||
High density lipoprotein decreases beta-amyloid toxicity in cortical cell culture | Q48761270 | ||
Abeta1-40 but not Abeta1-42 levels in cortex correlate with apolipoprotein E epsilon4 allele dosage in sporadic Alzheimer's disease. | Q48799582 | ||
Molecular, cellular, and pathologic characterization of HLA-DR immunoreactivity in normal elderly and Alzheimer's disease brain | Q48894740 | ||
P433 | issue | 4 | |
P921 | main subject | Alzheimer's disease | Q11081 |
lipoprotein | Q28350 | ||
microglia | Q1622829 | ||
P304 | page(s) | 316-324 | |
P577 | publication date | 2000-08-01 | |
P1433 | published in | Microscopy Research and Technique | Q59757 |
P1476 | title | Influence of lipoproteins on microglial degradation of Alzheimer's amyloid beta-protein | |
P478 | volume | 50 |
Q24323117 | Activation of microglia: a neuroinflammatory role for CAP37 |
Q38820863 | Alzheimer's Disease Risk Genes and Lipid Regulators. |
Q43556693 | Alzheimer's disease amyloid-beta binds copper and zinc to generate an allosterically ordered membrane-penetrating structure containing superoxide dismutase-like subunits |
Q35794580 | ApoE and Abeta1-42 interactions: effects of isoform and conformation on structure and function |
Q42744992 | ApoE mimetic peptide decreases Abeta production in vitro and in vivo. |
Q39155261 | Apolipoprotein E and Alzheimer's disease: the influence of apolipoprotein E on amyloid-β and other amyloidogenic proteins |
Q26858870 | Apolipoprotein E and apolipoprotein E receptors: normal biology and roles in Alzheimer disease |
Q34497951 | Apolipoprotein E: From lipid transport to neurobiology |
Q34680878 | Apolipoproteins in the brain: implications for neurological and psychiatric disorders |
Q33363912 | Cerebrospinal fluid-induced retardation of amyloid β aggregation correlates with Alzheimer's disease and the APOE ε4 allele |
Q28204071 | Changes in Apolipoprotein E Expression in Response to Dietary and Pharmacological Modulation of Cholesterol |
Q36355194 | Cholesterol: its regulation and role in central nervous system disorders |
Q33871345 | Current status on Alzheimer disease molecular genetics: from past, to present, to future |
Q48423106 | Differential effects of dietary fatty acids on the cerebral distribution of plasma-derived apo B lipoproteins with amyloid-beta |
Q30559265 | Effect of apolipoprotein E genotype and diet on apolipoprotein E lipidation and amyloid peptides: randomized clinical trial |
Q24338827 | Human APOE genotype affects intraneuronal Aβ1-42 accumulation in a lentiviral gene transfer model |
Q38543419 | Lipids in Amyloid-β Processing, Aggregation, and Toxicity |
Q33646882 | Metals and cholesterol: two sides of the same coin in Alzheimer's disease pathology |
Q37678533 | Microglial dysfunction in brain aging and Alzheimer's disease |
Q36348184 | Microglial malfunction: the third rail in the development of Alzheimer's disease |
Q34603092 | The role of apolipoprotein E in Alzheimer's disease |
Q46179010 | Why lipids are important for Alzheimer disease? |
Q43243545 | apoE isoform-specific disruption of amyloid beta peptide clearance from mouse brain |
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