Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice

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Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice is …
instance of (P31):
scholarly articleQ13442814

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P6179Dimensions Publication ID1019838160
P356DOI10.1038/KI.2010.132
P932PMC publication ID2906702
P698PubMed publication ID20445496
P5875ResearchGate publication ID44576073

P50authorMatthew C PickeringQ55692581
P2093author name stringPhilippe Azam
H Terence Cook
Elena Goicoechea de Jorge
Fadi Fakhouri
Frédérique Brune
P2860cites workDeletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II)Q24317382
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient miceQ24651118
Nephritogenic lambda light chain dimer: a unique human miniautoantibody against complement factor HQ28114862
Familial hemolytic uremic syndrome associated with complement factor H deficiencyQ33336276
Successful plasma therapy in hemolytic uremic syndrome with factor H deficiency.Q33338223
Anti-Factor H autoantibodies associated with atypical hemolytic uremic syndromeQ33364092
Successful plasma therapy for atypical hemolytic uremic syndrome caused by factor H deficiency owing to a novel mutation in the complement cofactor protein domain 15.Q33364782
Secondary failure of plasma therapy in factor H deficiencyQ33372254
Complete factor H deficiency-associated atypical hemolytic uremic syndrome in a neonateQ33374215
Translational mini-review series on complement factor H: renal diseases associated with complement factor H: novel insights from humans and animals.Q33378236
Complement factor H deficiency and posttransplantation glomerulonephritis with isolated C3 depositsQ33379098
Clinical practice guidelines for the management of atypical haemolytic uraemic syndrome in the United KingdomQ33386585
Hypocomplementemic autosomal recessive hemolytic uremic syndrome with decreased factor H.Q33504206
Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient miceQ34537391
Hereditary porcine membranoproliferative glomerulonephritis type II is caused by factor H deficiencyQ35552728
Extensive complement activation in hereditary porcine membranoproliferative glomerulonephritis type II (porcine dense deposit disease)Q35833465
Membranoproliferative glomerulonephritis type II (dense deposit disease): an updateQ36084453
Activation of the alternative pathway of complement by monoclonal lambda light chains in membranoproliferative glomerulonephritisQ36231096
New approaches to the treatment of dense deposit diseaseQ36860946
Decay-accelerating factor suppresses complement C3 activation and retards atherosclerosis in low-density lipoprotein receptor-deficient miceQ37362130
Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phaseQ41443111
Glomerular C3c localization indicates ongoing immune deposit formation and complement activation in experimental glomerulonephritisQ41885401
Serum C'3 lytic system in patients with glomerulonephritisQ44885697
Hypocomplementemic glomerulonephritis in an infant and mother. Evidence for an abnormal form of C3.Q45079393
Porcine membranoproliferative glomerulonephritis type II: an autosomal recessive deficiency of factor H.Q51047671
Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor HQ57089510
C3 nephritic factor (C3NeF): stabilization of fluid phase and cell-bound alternative pathway convertaseQ67740087
Eradication of porcine factor H deficiency in NorwayQ73319459
In situ complement activation in porcine membranoproliferative glomerulonephritis type IIQ74165088
Mouse podocyte complement factor H: the functional analog to human complement receptor 1Q79896677
C3 deposition glomerulopathy due to a functional factor H defectQ81654240
An inherited defect in the C3 convertase, C3b,Bb, associated with glomerulonephritisQ93856155
P433issue3
P407language of work or nameEnglishQ1860
P304page(s)279-286
P577publication date2010-05-05
P1433published inKidney InternationalQ6404823
P1476titleTreatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient mice
P478volume78

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cites work (P2860)
Q35922386Alternative Pathway Inhibition by Exogenous Factor H Fails to Attenuate Inflammation and Vascular Leakage in Experimental Pneumococcal Sepsis in Mice
Q51730313An Engineered Complement Factor H Construct for Treatment of C3 Glomerulopathy.
Q42625961An extended mini-complement factor H molecule ameliorates experimental C3 glomerulopathy.
Q21202864Atypical hemolytic uremic syndrome
Q37644173C3 dysregulation due to factor H deficiency is mannan-binding lectin-associated serine proteases (MASP)-1 and MASP-3 independent in vivo.
Q35531724CFH 184G as a genetic risk marker for anterior uveitis in Chinese females
Q40821027Complement Factor H Serum Levels Determine Resistance to Pneumococcal Invasive Disease
Q36145970Complement factor H and interleukin gene polymorphisms in patients with non-infectious intermediate and posterior uveitis
Q92294442Complement factor H contributes to mortality in humans and mice with bacterial meningitis
Q39036058Complement factor H in host defense and immune evasion.
Q33411137Complement regulation in renal disease models
Q26795441Complement regulation: physiology and disease relevance
Q38614302Complement, a target for therapy in inflammatory and degenerative diseases.
Q33396792Complement-mediated injury and protection of endothelium: lessons from atypical haemolytic uraemic syndrome
Q37286653Dense deposit disease and C3 glomerulopathy
Q35124165Dense deposit disease.
Q37017177Distinct roles for the complement regulators factor H and Crry in protection of the kidney from injury.
Q40865063Efficacy of Targeted Complement Inhibition in Experimental C3 Glomerulopathy
Q90496015Emerging immunotherapies for autoimmune kidney disease
Q58831414Endothelial progenitor cell-derived extracellular vesicles protect from complement-mediated mesangial injury in experimental anti-Thy1.1 glomerulonephritis
Q43083299Expression of human complement factor H prevents age-related macular degeneration-like retina damage and kidney abnormalities in aged Cfh knockout mice
Q34699741Factor H binds to the hypervariable region of many Streptococcus pyogenes M proteins but does not promote phagocytosis resistance or acute virulence
Q35030648Familial C3 glomerulopathy associated with CFHR5 mutations: clinical characteristics of 91 patients in 16 pedigrees
Q36016859IgM exacerbates glomerular disease progression in complement-induced glomerulopathy
Q35922195Impact of Reducing Complement Inhibitor Binding on the Immunogenicity of Native Neisseria meningitidis Outer Membrane Vesicles
Q36509318Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency
Q33437488Moss-Produced, Glycosylation-Optimized Human Factor H for Therapeutic Application in Complement Disorders
Q38770928Mutations in Complement Factor H Impair Alternative Pathway Regulation on Mouse Glomerular Endothelial Cells in Vitro
Q33410111Novel use of intravenous immunoglobulin G in complement factor H missense mutation: a case report
Q38048606Pathogenesis of the C3 glomerulopathies and reclassification of MPGN.
Q38991019Protection of host cells by complement regulators.
Q38088187Recent insights into C3 glomerulopathy
Q38591917Role of complement in glomerular diseases
Q36563619Selectivity of C3-opsonin targeted complement inhibitors: A distinct advantage in the protection of erythrocytes from paroxysmal nocturnal hemoglobinuria patients.
Q37260204Soluble CR1 therapy improves complement regulation in C3 glomerulopathy
Q40715358The Complement Inhibitor Factor H Generates an Anti-Inflammatory and Tolerogenic State in Monocyte-Derived Dendritic Cells
Q35624672Treatment options for C3 glomerulopathy
Q33403607Use of eculizumab for atypical haemolytic uraemic syndrome and C3 glomerulopathies
Q27318468Virulence of Group A Streptococci Is Enhanced by Human Complement Inhibitors

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