Dense deposit disease.

scientific article

Dense deposit disease. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

External links are
P356DOI10.1016/J.MOLIMM.2011.04.005
P932PMC publication ID3142282
P698PubMed publication ID21601923
P5875ResearchGate publication ID51155542

P50authorMatthew C PickeringQ55692581
Richard J SmithQ58399821
P2093author name stringClaire L. Harris
Claire L Harris
Matthew C. Pickering
P2860cites workDeletion of Lys224 in regulatory domain 4 of Factor H reveals a novel pathomechanism for dense deposit disease (MPGN II)Q24317382
Control of the amplification convertase of complement by the plasma protein beta1HQ24561671
Structural basis for engagement by complement factor H of C3b on a self surfaceQ24604385
Structure of complement fragment C3b-factor H and implications for host protection by complement regulatorsQ24646723
Factor I is required for the development of membranoproliferative glomerulonephritis in factor H-deficient miceQ24651118
Extended haplotypes in the complement factor H (CFH) and CFH-related (CFHR) family of genes protect against age-related macular degeneration: characterization, ethnic distribution and evolutionary implicationsQ24681724
Nephritogenic lambda light chain dimer: a unique human miniautoantibody against complement factor HQ28114862
Dense deposit disease: a variant of membranoproliferative glomerulonephritisQ28144476
Complement. First of two partsQ28210663
Complement. Second of two partsQ28211878
Structure of C3b in complex with CRIg gives insights into regulation of complement activationQ28269302
Structure of C3b reveals conformational changes that underlie complement activityQ28269312
Role of vitronectin and its receptors in haemostasis and vascular remodelingQ28272554
Structures of complement component C3 provide insights into the function and evolution of immunityQ28273530
Production of biologically active recombinant human factor H in PhyscomitrellaQ28290970
An imbalance of human complement regulatory proteins CFHR1, CFHR3 and factor H influences risk for age-related macular degeneration (AMD)Q28293350
Dense deposit disease is not a membranoproliferative glomerulonephritisQ28295719
Factor H facilitates the clearance of GBM bound iC3b by controlling C3 activation in fluid phaseQ41443111
Small margin excision of periocular basal cell carcinomasQ42451228
Functional and morphological macular abnormalities in membranoproliferative glomerulonephritis type II.Q42949064
Evidence that production of autoantibody to the alternative pathway C3 convertase is a normal physiologic eventQ44437858
Serum C'3 lytic system in patients with glomerulonephritisQ44885697
Hypocomplementemic glomerulonephritis in an infant and mother. Evidence for an abnormal form of C3.Q45079393
Recurrence of membranoproliferative glomerulonephritis type II in renal allografts: The North American Pediatric Renal Transplant Cooperative Study experienceQ46486094
Inherited factor H deficiency and collagen type III glomerulopathyQ49287293
A descriptive study of individuals with membranoproliferative glomerulonephritis.Q51745279
Uncontrolled C3 activation causes membranoproliferative glomerulonephritis in mice deficient in complement factor HQ57089510
H deficiency in two brothers with atypical dense intramembranous deposit diseaseQ59619455
On the origin of C3 nephritic factor (antibody to the alternative pathway C3 convertase): evidence for the Adam and Eve concept of autoantibody productionQ67546253
C3 nephritic factor (C3NeF): stabilization of fluid phase and cell-bound alternative pathway convertaseQ67740087
Two types of C3 nephritic factor: properdin-dependent C3NeF and properdin-independent C3NeFQ68424301
Effect of decay-accelerating factor on the assembly of the classical and alternative pathway C3 convertases in the presence of C4 or C3 nephritic factorQ69124128
Biological significance of the C3 nephritic factor in membranoproliferative glomerulonephritisQ70539365
Hypocomplementaemia due to a genetic deficiency of beta 1H globulinQ70567912
Stabilization of homologous and heterologous cell-bound amplification convertases, C3bBb, by C3 nephritic factorQ72638926
Protection of the classical and alternative complement pathway C3 convertases, stabilized by nephritic factors, from decay by the human C3b receptorQ72834641
In situ complement activation in porcine membranoproliferative glomerulonephritis type IIQ74165088
Complement analysis in children with idiopathic membranoproliferative glomerulonephritis: a long-term follow-upQ74267577
Factor H deficiency and fibrillary glomerulopathyQ75434821
Potential protective role of apoprotein J (clusterin) in atherogenesis: binding to enzymatically modified low-density lipoprotein reduces fatty acid-mediated cytotoxicityQ81607398
Anti-factor B autoantibody in dense deposit diseaseQ83087439
Factor H-related protein 1 (CFHR-1) inhibits complement C5 convertase activity and terminal complex formationQ84071466
Production of biologically active complement factor H in therapeutically useful quantitiesQ28300280
Functional properties of membrane cofactor protein of complementQ28610962
Mutations in factor H reduce binding affinity to C3b and heparin and surface attachment to endothelial cells in hemolytic uremic syndromeQ33347509
Heterozygous and homozygous factor h deficiencies associated with hemolytic uremic syndrome or membranoproliferative glomerulonephritis: report and genetic analysis of 16 casesQ33359650
Functional analysis in serum from atypical Hemolytic Uremic Syndrome patients reveals impaired protection of host cells associated with mutations in factor H.Q33360768
Complement regulators and inhibitory proteinsQ33386110
The role of complement in AMD.Q33391415
Disease-associated N-terminal complement factor H mutations perturb cofactor and decay-accelerating activitiesQ33393852
Glomeruli of Dense Deposit Disease contain components of the alternative and terminal complement pathwayQ33403738
Treatment with human complement factor H rapidly reverses renal complement deposition in factor H-deficient miceQ34005720
Human C3 mutation reveals a mechanism of dense deposit disease pathogenesis and provides insights into complement activation and regulationQ34162206
Clinical features and metabolic and autoimmune derangements in acquired partial lipodystrophy: report of 35 cases and review of the literatureQ34293159
Prevention of C5 activation ameliorates spontaneous and experimental glomerulonephritis in factor H-deficient miceQ34537391
Complement Receptor 1: disease associations and therapeutic implications.Q34878497
Heterogeneity of nephritic factor and its identification as an immunoglobulinQ35052508
Allelic variants of complement genes associated with dense deposit diseaseQ35142753
Pathogenesis of lesions in late age-related macular diseaseQ35688114
The molecular basis for hereditary porcine membranoproliferative glomerulonephritis type II: point mutations in the factor H coding sequence block protein secretionQ35748229
Factor H mediated cell surface protection from complement is critical for the survival of PNH erythrocytes.Q35990700
Membranoproliferative glomerulonephritis type II (dense deposit disease): an updateQ36084453
Complement decay accelerating factor (DAF)/CD55 in cancer.Q36399496
Alternative roles for CD59.Q36555055
The role of CR2 in autoimmunity.Q36572973
Y402H polymorphism of complement factor H affects binding affinity to C-reactive proteinQ36860930
New approaches to the treatment of dense deposit diseaseQ36860946
Complement receptors CD21 and CD35 in humoral immunityQ36938627
Complement driven by conformational changesQ37026644
Translational mini-review series on complement factor H: structural and functional correlations for factor H.Q37032788
Functional basis of protection against age-related macular degeneration conferred by a common polymorphism in complement factor BQ37132696
A role of macrophage complement receptor CRIg in immune clearance and inflammation.Q37254633
Complement in human diseases: Lessons from complement deficienciesQ37501005
The disease-protective complement factor H allotypic variant Ile62 shows increased binding affinity for C3b and enhanced cofactor activityQ39968584
Idiopathic mesangiocapillary glomerulonephritis. Comparison of types I and II in children and adults and long-term prognosisQ40144637
Defective complement control of factor H (Y402H) and FHL-1 in age-related macular degenerationQ40151482
Further evidence for the antibody nature of C3 nephritic factor (C3NeF)Q41067359
P433issue14
P304page(s)1604-1610
P577publication date2011-05-24
2011-08-01
P1433published inMolecular ImmunologyQ6895954
P1476titleDense deposit disease
P478volume48

Reverse relations

cites work (P2860)
Q30409539A humanized antibody that regulates the alternative pathway convertase: potential for therapy of renal disease associated with nephritic factors
Q38232593An emerging molecular understanding and novel targeted treatment approaches in pediatric kidney diseases
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Q42246527C3 nephritic factor associated with C3 glomerulopathy in children
Q30274884C5 inhibition prevents renal failure in a mouse model of lethal C3 glomerulopathy
Q35758595Causes of alternative pathway dysregulation in dense deposit disease
Q35580577Clinical features and outcomes of 98 children and adults with dense deposit disease.
Q35246525Clinico-pathologic spectrum of C3 glomerulopathy-an Indian experience
Q30415634Combination of factor H mutation and properdin deficiency causes severe C3 glomerulonephritis
Q26829790Complement cascade and kidney transplantation: The rediscovery of an ancient enemy
Q40986583Complement in Non-Antibody-Mediated Kidney Diseases.
Q37522557Complement related kidney diseases: Recurrence after transplantation
Q47108030Complement-Mediated Glomerular Diseases: A Tale of 3 Pathways
Q58120548Complement-mediated renal diseases after kidney transplantation - current diagnostic and therapeutic options in and recurrent diseases
Q85950139Curcumin alleviates immune-complex-mediated glomerulonephritis in factor-H-deficient mice
Q34574482Current concepts in C3 glomerulopathy
Q34465747Defective complement inhibitory function predisposes to renal disease
Q37286653Dense deposit disease and C3 glomerulopathy
Q41377869Disease-linked mutations in factor H reveal pivotal role of cofactor activity in self-surface-selective regulation of complement activation
Q50025267Drug-Induced Pseudoallergy: A Review of the Causes and Mechanisms
Q35597310Eculizumab and recurrent C3 glomerulonephritis
Q59273614Eculizumab in dense-deposit disease after renal transplantation
Q40865063Efficacy of Targeted Complement Inhibition in Experimental C3 Glomerulopathy
Q36438860Kidney diseases caused by complement dysregulation: acquired, inherited, and still more to come
Q36509318Loss of properdin exacerbates C3 glomerulopathy resulting from factor H deficiency
Q27008508Membranoproliferative glomerulonephritis and C3 glomerulopathy: resolving the confusion
Q64039347Nephritic Factors: An Overview of Classification, Diagnostic Tools and Clinical Associations
Q34146380New insights into disease-specific absence of complement factor H related protein C in mouse models of spontaneous autoimmune diseases
Q38048606Pathogenesis of the C3 glomerulopathies and reclassification of MPGN.
Q89080771Prevention of Fatal C3 Glomerulopathy by Recombinant Complement Receptor of the Ig Superfamily
Q38118454Properdin in complement activation and tissue injury
Q38088187Recent insights into C3 glomerulopathy
Q26741542Reclassification of membranoproliferative glomerulonephritis: Identification of a new GN: C3GN
Q35532337Regulating complement in the kidney: insights from CFHR5 nephropathy
Q55710477Retinal Basal Laminar Deposits in Complement fH/fP Mouse Model of Dense Deposit Disease.
Q43162540Role of Factor H and Related Proteins in Regulating Complement Activation in the Macula, and Relevance to Age-Related Macular Degeneration.
Q37260204Soluble CR1 therapy improves complement regulation in C3 glomerulopathy
Q37275993The incidence of possible causes of membranoproliferative glomerulonephritis: a single-center experience
Q38062343The renal biopsy in the genomic era.
Q89166249Timing and mechanism of conceptus demise in a complement regulatory membrane protein deficient mouse
Q48252388Treating C3 glomerulopathy with eculizumab.

main subject (P921)
Q64244437Glomerular C4d Staining Does Not Exclude a C3 Glomerulopathy
Q64049358Successful therapy of C3Nef-positive C3 glomerulopathy with plasma therapy and immunosuppression

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