Enteropathogenic Escherichia coli activates ezrin, which participates in disruption of tight junction barrier function.

scientific article

Enteropathogenic Escherichia coli activates ezrin, which participates in disruption of tight junction barrier function. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1128/IAI.69.9.5679-5688.2001
P932PMC publication ID98684
P698PubMed publication ID11500444

P50authorHolly Falk-KrzesinskiQ43179609
P2093author name stringM Arpin
G Hecht
A Koutsouris
I Simonovic
P2860cites workDiarrheagenic Escherichia coliQ24533466
Ezrin/radixin/moesin (ERM) proteins bind to a positively charged amino acid cluster in the juxta-membrane cytoplasmic domain of CD44, CD43, and ICAM-2Q24676628
ERM (ezrin/radixin/moesin)-based molecular mechanism of microvillar breakdown at an early stage of apoptosisQ24676652
Rho-kinase phosphorylates COOH-terminal threonines of ezrin/radixin/moesin (ERM) proteins and regulates their head-to-tail associationQ24678197
Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin familyQ24678695
Morphogenic effects of ezrin require a phosphorylation-induced transition from oligomers to monomers at the plasma membraneQ24683879
Cleavage of Structural Proteins during the Assembly of the Head of Bacteriophage T4Q25938983
Structure of the ERM protein moesin reveals the FERM domain fold masked by an extended actin binding tail domainQ27622801
Characterization of the interaction between protein 4.1R and ZO-2. A possible link between the tight junction and the actin cytoskeletonQ28139599
A gene family consisting of ezrin, radixin and moesin. Its specific localization at actin filament/plasma membrane association sitesQ28202167
Identification of the two major epidermal growth factor-induced tyrosine phosphorylation sites in the microvillar core protein ezrinQ46269943
The 18th C.L. Oakley Lecture. Pathogenicity of enteropathogenic Escherichia coliQ47763247
Small GTP-binding proteins of the Rho- and Ras-subfamilies are not involved in the actin rearrangements induced by attaching and effacing Escherichia coliQ47806780
Enteropathogenic Escherichia coli dephosphorylates and dissociates occludin from intestinal epithelial tight junctions.Q54021246
Structural analysis of a human intestinal epithelial cell line.Q54407374
Ezrin is concentrated in the apical microvilli of a wide variety of epithelial cells whereas moesin is found primarily in endothelial cellsQ72572435
A functional role for ezrin during Shigella flexneri entry into epithelial cellsQ77855033
C-terminal threonine phosphorylation activates ERM proteins to link the cell's cortical lipid bilayer to the cytoskeletonQ77905807
Translocated EspF protein from enteropathogenic Escherichia coli disrupts host intestinal barrier functionQ28359876
The ezrin protein family: membrane-cytoskeleton interactions and disease associationsQ30428648
Adhesion of enteropathogenic Escherichia coli to human intestinal enterocytes and cultured human intestinal mucosa.Q30451109
Activation of host cell protein kinase C by enteropathogenic Escherichia coliQ30452842
Effect of hepatocyte growth factor on assembly of zonula occludens-1 protein at the plasma membraneQ32040911
Enteropathogenic Escherichia coli contains a putative type III secretion system necessary for the export of proteins involved in attaching and effacing lesion formationQ34022530
Dephosphorylation of ezrin as an early event in renal microvillar breakdown and anoxic injuryQ34060749
ERM (ezrin/radixin/moesin) family: from cytoskeleton to signal transductionQ34414797
ERM proteins: head-to-tail regulation of actin-plasma membrane interactionQ34417697
The eaeB gene of enteropathogenic Escherichia coli is necessary for signal transduction in epithelial cellsQ34531321
Rapid modulation of electrolyte transport in Caco-2 cell monolayers by enteropathogenic Escherichia coli (EPEC) infectionQ35349325
Phosphorylation of myosin light chain at distinct sites and its association with the cytoskeleton during enteropathogenic Escherichia coli infectionQ35501685
Attachment of a noninvasive enteric pathogen, enteropathogenic Escherichia coli, to cultured human intestinal epithelial monolayers induces transmigration of neutrophilsQ35527637
Rapid phosphorylation and reorganization of ezrin and spectrin accompany morphological changes induced in A-431 cells by epidermal growth factorQ36219929
Ezrin contains cytoskeleton and membrane binding domains accounting for its proposed role as a membrane-cytoskeletal linkerQ36232246
Ezrin is an effector of hepatocyte growth factor-mediated migration and morphogenesis in epithelial cellsQ36268138
Ezrin promotes morphogenesis of apical microvilli and basal infoldings in retinal pigment epitheliumQ36326132
ERM family members as molecular linkers between the cell surface glycoprotein CD44 and actin-based cytoskeletonsQ36382880
Cytoskeletal composition of attaching and effacing lesions associated with enteropathogenic Escherichia coli adherence to HeLa cellsQ36946588
Attaching and effacing activities of rabbit and human enteropathogenic Escherichia coli in pig and rabbit intestines.Q37106331
Regulation of Cytoskeleton and Cell Adhesions by the Small GTPase Rho and Its Targets.Q37828684
Agents that inhibit Rho, Rac, and Cdc42 do not block formation of actin pedestals in HeLa cells infected with enteropathogenic Escherichia coliQ39570838
Enteropathogenic Escherichia coli decreases the transepithelial electrical resistance of polarized epithelial monolayers.Q40267720
Hepatocyte growth factor/scatter factor effects on epithelia. Regulation of intercellular junctions in transformed and nontransformed cell lines, basolateral polarization of c-met receptor in transformed and natural intestinal epithelia, and inductiQ40336340
Enteropathogenic E. coli attenuates secretagogue-induced net intestinal ion transport but not Cl- secretionQ40968480
Hijacking host cell signal transduction mechanisms during infection with enteropathogenic Escherichia coliQ41061055
Enteropathogenic Escherichia coli-induced myosin light chain phosphorylation alters intestinal epithelial permeabilityQ41077484
Activation of NF-kappaB in intestinal epithelial cells by enteropathogenic Escherichia coli.Q41081300
The secretion-stimulated 80K phosphoprotein of parietal cells is ezrin, and has properties of a membrane cytoskeletal linker in the induced apical microvilliQ41081966
Infection of T84 cells with enteropathogenic Escherichia coli alters barrier and transport functionsQ41207334
Induction of tyrosine phosphorylation and translocation of ezrin by hepatocyte growth factor/scatter factor.Q41257814
Enteropathogenic Escherichia coli adherence to intestinal epithelial monolayers diminishes barrier functionQ41372072
Signal transduction in human epithelial cells infected with attaching and effacing Escherichia coli in vitro.Q41469608
Insertion of EspD into epithelial target cell membranes by infecting enteropathogenic Escherichia coliQ41483133
Signal transduction between enteropathogenic Escherichia coli (EPEC) and epithelial cells: EPEC induces tyrosine phosphorylation of host cell proteins to initiate cytoskeletal rearrangement and bacterial uptakeQ41533005
Ezrin: a protein requiring conformational activation to link microfilaments to the plasma membrane in the assembly of cell surface structuresQ41640261
Morphology of the differentiation and maturation of LLC-PK1 epitheliaQ41745184
Microinjected antibodies against the cytoplasmic domain of vesicular stomatitis virus glycoprotein block its transport to the cell surfaceQ42567664
Ezrin has a COOH-terminal actin-binding site that is conserved in the ezrin protein familyQ42720142
Rho- and rac-dependent assembly of focal adhesion complexes and actin filaments in permeabilized fibroblasts: an essential role for ezrin/radixin/moesin proteinsQ42796333
Immunofluorescence detection of ezrin/radixin/moesin (ERM) proteins with their carboxyl-terminal threonine phosphorylated in cultured cells and tissuesQ42818127
Purification of a 20 kDa phosphoprotein from epithelial cells and identification as a myosin light chain. Phosphorylation induced by enteropathogenic Escherichia coli and phorbol esterQ44606709
P433issue9
P407language of work or nameEnglishQ1860
P921main subjectEscherichia coliQ25419
Enteropathogenic Escherichia coliQ13419512
enteropathogenQ63500873
P304page(s)5679-5688
P577publication date2001-09-01
P1433published inInfection and ImmunityQ6029193
P1476titleEnteropathogenic Escherichia coli activates ezrin, which participates in disruption of tight junction barrier function
P478volume69

Reverse relations

cites work (P2860)
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