RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes.

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RNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes. is …
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scholarly articleQ13442814

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P356DOI10.1038/NSMB1352
P932PMC publication ID2836588
P698PubMed publication ID18157150
P5875ResearchGate publication ID5692374

P50authorJoaquín M EspinosaQ40442701
Kira Glover-CutterQ42177120
David L BentleyQ55137036
P2093author name stringSoojin Kim
P2860cites workIntegrator, a multiprotein mediator of small nuclear RNA processing, associates with the C-terminal repeat of RNA polymerase IIQ24338780
Analysis of a noncanonical poly(A) site reveals a tripartite mechanism for vertebrate poly(A) site recognitionQ24529123
Symplekin and multiple other polyadenylation factors participate in 3'-end maturation of histone mRNAsQ24537115
Pause sites promote transcriptional termination of mammalian RNA polymerase IIQ24548945
RNA polymerase II accumulation in the promoter-proximal region of the dihydrofolate reductase and gamma-actin genesQ24550573
Functional interactions of RNA-capping enzyme with factors that positively and negatively regulate promoter escape by RNA polymerase IIQ24562164
Transcription elongation factor hSPT5 stimulates mRNA cappingQ24601724
The multifunctional protein p54nrb/PSF recruits the exonuclease XRN2 to facilitate pre-mRNA 3' processing and transcription terminationQ24671920
Different phosphorylated forms of RNA polymerase II and associated mRNA processing factors during transcriptionQ28131686
Transcription factor TFIID recruits factor CPSF for formation of 3' end of mRNAQ28249862
Controlling the elongation phase of transcription with P-TEFbQ28255518
Polyadenylation factor CPSF-73 is the pre-mRNA 3'-end-processing endonucleaseQ28275724
Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesisQ28609911
An extensive network of coupling among gene expression machinesQ29547273
Phosphorylation and functions of the RNA polymerase II CTDQ29614764
Dynamic association of capping enzymes with transcribing RNA polymerase IIQ29614771
RNA polymerase II and the integration of nuclear eventsQ29614772
EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.Q30303893
The poly(A)-dependent transcriptional pause is mediated by CPSF acting on the body of the polymeraseQ34004722
Viral and cellular mRNA capping: past and prospectsQ34070118
Tat stimulates cotranscriptional capping of HIV mRNA.Q34156984
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
Gene-specific requirement for P-TEFb activity and RNA polymerase II phosphorylation within the p53 transcriptional programQ34471112
Terminating the transcript: breaking up is hard to do.Q34520033
Breaking barriers to transcription elongationQ34561019
Genomic localization of RNA binding proteins reveals links between pre-mRNA processing and transcriptionQ34703149
Origins of mRNA identity: capping enzymes bind to the phosphorylated C-terminal domain of RNA polymerase IIQ36158890
In vivo transcriptional pausing and cap formation on three Drosophila heat shock genesQ36499506
Nucleosome displacement in transcriptionQ36554288
In vivo dynamics of RNA polymerase II transcription.Q37088096
Promoter-proximal pausing by RNA polymerase II in vitro: transcripts shorter than 20 nucleotides are not cappedQ37604963
Specific transcriptional pausing activates polyadenylation in a coupled in vitro systemQ38323992
RNA polymerase II carboxy-terminal domain phosphorylation is required for cotranscriptional pre-mRNA splicing and 3'-end formationQ40025884
Ribozyme cleavage reveals connections between mRNA release from the site of transcription and pre-mRNA processing.Q40342109
Transcriptional termination in the Balbiani ring 1 gene is closely coupled to 3'-end formation and excision of the 3'-terminal intronQ40445738
Vaccinia virus capping enzyme is a transcription initiation factorQ41082113
Cotranscriptional spliceosome assembly dynamics and the role of U1 snRNA:5'ss base pairing in yeastQ41355869
The conserved AAUAAA hexamer of the poly(A) signal can act alone to trigger a stable decrease in RNA polymerase II transcription velocityQ41875673
3' end formation of U1 snRNA precursors is coupled to transcription from snRNA promotersQ43562909
Interactions between fission yeast mRNA capping enzymes and elongation factor Spt5.Q43917514
Functional interaction of yeast pre-mRNA 3' end processing factors with RNA polymerase II.Q44017745
Functional coupling of capping and transcription of mRNA.Q44199580
Coordination of transcription, RNA processing, and surveillance by P-TEFb kinase on heat shock genesQ44734152
The RNA tether from the poly(A) signal to the polymerase mediates coupling of transcription to cleavage and polyadenylationQ46080085
Functional coupling of cleavage and polyadenylation with transcription of mRNA.Q46616243
Pcf11 is a termination factor in Drosophila that dismantles the elongation complex by bridging the CTD of RNA polymerase II to the nascent transcriptQ46875108
Formation of the 3' end of U1 snRNA requires compatible snRNA promoter elementsQ69638046
Positive patches and negative noodles: linking RNA processing to transcription?Q70716691
Factor-dependent transcription termination by vaccinia RNA polymerase. Kinetic coupling and requirement for ATP hydrolysisQ72331813
Cotranscriptional coupling of splicing factor recruitment and precursor messenger RNA splicing in mammalian cellsQ80143464
The polyadenylation factor CPSF-73 is involved in histone-pre-mRNA processingQ81327465
P433issue1
P304page(s)71-78
P577publication date2007-12-23
P1433published inNature Structural & Molecular BiologyQ1071739
P1476titleRNA polymerase II pauses and associates with pre-mRNA processing factors at both ends of genes
P478volume15