scholarly article | Q13442814 |
P50 | author | Tyler Jacks | Q7860044 |
Xin Teng | Q57556129 | ||
Nada Y Kalaany | Q60683425 | ||
Eileen White | Q61820577 | ||
Joshua D Rabinowitz | Q90243141 | ||
P2093 | author name string | Sandy Price | |
Chang S Chan | |||
Sinan Khor | |||
Gizem Karsli-Uzunbas | |||
Saurabh V Laddha | |||
Jessie Yanxiang Guo | |||
P2860 | cites work | Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice | Q24303752 |
In vivo analysis of autophagy in response to nutrient starvation using transgenic mice expressing a fluorescent autophagosome marker | Q24633015 | ||
Autophagy-mediated tumor promotion | Q27011920 | ||
Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources | Q27860739 | ||
Suppression of basal autophagy in neural cells causes neurodegenerative disease in mice | Q28131756 | ||
Loss of autophagy in the central nervous system causes neurodegeneration in mice | Q28131804 | ||
Deletion of the developmentally essential gene ATR in adult mice leads to age-related phenotypes and stem cell loss | Q28274165 | ||
Impairment of starvation-induced and constitutive autophagy in Atg7-deficient mice | Q28588080 | ||
Autophagy: renovation of cells and tissues | Q29547206 | ||
The role of autophagy during the early neonatal starvation period | Q29547489 | ||
Autophagy defends cells against invading group A Streptococcus | Q29615620 | ||
Pancreatic cancers require autophagy for tumor growth | Q29620331 | ||
Activated Ras requires autophagy to maintain oxidative metabolism and tumorigenesis. | Q34626763 | ||
Liver autophagy contributes to the maintenance of blood glucose and amino acid levels | Q35146053 | ||
Uncoupling cancer mutations reveals critical timing of p53 loss in sarcomagenesis | Q35177312 | ||
Liver-specific loss of Atg5 causes persistent activation of Nrf2 and protects against acetaminophen-induced liver injury | Q35969312 | ||
Deconvoluting the context-dependent role for autophagy in cancer | Q36876716 | ||
Autophagy suppresses progression of K-ras-induced lung tumors to oncocytomas and maintains lipid homeostasis | Q37019194 | ||
Autophagy opposes p53-mediated tumor barrier to facilitate tumorigenesis in a model of PALB2-associated hereditary breast cancer. | Q37086261 | ||
Autophagy regulates adipose mass and differentiation in mice | Q37403082 | ||
Adipose-specific deletion of autophagy-related gene 7 (atg7) in mice reveals a role in adipogenesis | Q37446431 | ||
Autophagy-dependent production of secreted factors facilitates oncogenic RAS-driven invasion | Q37692748 | ||
Mechanisms regulating skeletal muscle growth and atrophy | Q38091731 | ||
Autophagy is required for mitochondrial function, lipid metabolism, growth, and fate of KRAS(G12D)-driven lung tumors | Q38130127 | ||
p53 status determines the role of autophagy in pancreatic tumour development | Q39048945 | ||
Autophagy sustains mitochondrial glutamine metabolism and growth of BrafV600E-driven lung tumors | Q39107065 | ||
Analysis of a lung defect in autophagy-deficient mouse strains | Q39801601 | ||
Autophagy-deficient mice develop multiple liver tumors | Q42099409 | ||
Loss of autophagy diminishes pancreatic beta cell mass and function with resultant hyperglycemia | Q42442810 | ||
Autophagy is important in islet homeostasis and compensatory increase of beta cell mass in response to high-fat diet | Q42442818 | ||
Lipophagy: connecting autophagy and lipid metabolism | Q42556437 | ||
Assessing therapeutic responses in Kras mutant cancers using genetically engineered mouse models | Q43056152 | ||
Autophagy is required to maintain muscle mass. | Q51411361 | ||
A dual role for autophagy in a murine model of lung cancer | Q57183947 | ||
P433 | issue | 8 | |
P921 | main subject | glucose | Q37525 |
autophagy | Q288322 | ||
P304 | page(s) | 914-927 | |
P577 | publication date | 2014-05-29 | |
P1433 | published in | Cancer Discovery | Q15724440 |
P1476 | title | Autophagy is required for glucose homeostasis and lung tumor maintenance | |
P478 | volume | 4 |
Q57191934 | A Potent and Selective ULK1 Inhibitor Suppresses Autophagy and Sensitizes Cancer Cells to Nutrient Stress |
Q99566234 | A bidirectional crosstalk between autophagy and TP53 determines the pace of aging |
Q89589492 | A novel Atg5-shRNA mouse model enables temporal control of Autophagy in vivo |
Q41753200 | ATG7 promotes the tumorigenesis of lung cancer but might be dispensable for prognosis predication: a clinicopathologic study |
Q38795278 | Activating autophagy to potentiate immunogenic chemotherapy and radiation therapy |
Q92642778 | Adaptive Responses as Mechanisms of Resistance to BRAF Inhibitors in Melanoma |
Q39461509 | Altered glycogen metabolism causes hepatomegaly following an Atg7 deletion. |
Q39414846 | An Emerging Role for Tubulin Isotypes in Modulating Cancer Biology and Chemotherapy Resistance |
Q99406594 | Anti-tumor immunity influences cancer cell reliance upon ATG7 |
Q38910539 | Atg7 Overcomes Senescence and Promotes Growth of BrafV600E-Driven Melanoma |
Q36603857 | Atg7 cooperates with Pten loss to drive prostate cancer tumor growth |
Q26781433 | Atg7 in development and disease: panacea or Pandora's Box? |
Q96304244 | Autophagosome biogenesis and human health |
Q40805952 | Autophagy Inhibition Dysregulates TBK1 Signaling and Promotes Pancreatic Inflammation. |
Q30358631 | Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3 |
Q89224112 | Autophagy Regulates the Liver Clock and Glucose Metabolism by Degrading CRY1 |
Q46675174 | Autophagy acts through TRAF3 and RELB to regulate gene expression via antagonism of SMAD proteins. |
Q49388079 | Autophagy and Disease |
Q60912923 | Autophagy and Its Role in Protein Secretion: Implications for Cancer Therapy |
Q39280823 | Autophagy and Tumor Metabolism |
Q41911940 | Autophagy and cancer - insights from mouse models |
Q92407174 | Autophagy and disease: unanswered questions |
Q35330324 | Autophagy and its effects: making sense of double-edged swords |
Q38796071 | Autophagy and p53. |
Q52574176 | Autophagy as a cytoprotective mechanism in esophageal squamous cell carcinoma. |
Q60198552 | Autophagy as a promoter of longevity: insights from model organisms |
Q99418507 | Autophagy as a therapeutic target in pancreatic cancer |
Q38547568 | Autophagy at the crossroads of catabolism and anabolism |
Q92552819 | Autophagy gene haploinsufficiency drives chromosome instability, increases migration, and promotes early ovarian tumors |
Q88515082 | Autophagy in C. elegans development |
Q26999216 | Autophagy in cancer |
Q38946182 | Autophagy in cancer metastasis |
Q91973791 | Autophagy in cancer: moving from understanding mechanism to improving therapy responses in patients |
Q26996211 | Autophagy in cellular metabolism and cancer |
Q55388737 | Autophagy in the Tumor or in the Host: Which Plays a Greater Supportive Role? |
Q91743614 | Autophagy in the mammalian nervous system: a primer for neuroscientists |
Q36609034 | Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis |
Q33713052 | Autophagy inhibitor facilitates gefitinib sensitivity in vitro and in vivo by activating mitochondrial apoptosis in triple negative breast cancer. |
Q38666985 | Autophagy inhibitors |
Q59066319 | Autophagy maintains tumour growth through circulating arginine |
Q90470329 | Autophagy promotes mammalian survival by suppressing oxidative stress and p53 |
Q37212988 | Autophagy provides metabolic substrates to maintain energy charge and nucleotide pools in Ras-driven lung cancer cells |
Q98463461 | Autophagy regulates fatty acid availability for oxidative phosphorylation through mitochondria-endoplasmic reticulum contact sites |
Q64073539 | Autophagy regulates lipid metabolism through selective turnover of NCoR1 |
Q47742163 | Autophagy sustains pancreatic cancer growth through both cell autonomous and non-autonomous mechanisms |
Q33923174 | Autophagy, Metabolism, and Cancer |
Q53210815 | Autophagy, Metabolism, and Cancer. |
Q90661029 | Autophagy, cancer stem cells and drug resistance |
Q42376893 | Autophagy-monitoring and autophagy-deficient mice |
Q90706502 | BCR-ABL Independent Mechanisms of Resistance in Chronic Myeloid Leukemia |
Q36379709 | BECLIN 1-VPS34 COMPLEX ARCHITECTURE: UNDERSTANDING THE NUTS AND BOLTS OF THERAPEUTIC TARGETS. |
Q91725117 | Blockade of RAF and autophagy is the one-two punch to take out Ras |
Q92901911 | Blocking transmembrane219 protein signaling inhibits autophagy and restores normal cell death |
Q54118859 | CK1α suppresses lung tumour growth by stabilizing PTEN and inducing autophagy. |
Q48277050 | Ca2+-dependent demethylation of phosphatase PP2Ac promotes glucose deprivation-induced cell death independently of inhibiting glycolysis. |
Q41951413 | Calcium homeostasis and ER stress in control of autophagy in cancer cells |
Q33700636 | Cancer cachexia associates with a systemic autophagy-inducing activity mimicked by cancer cell-derived IL-6 trans-signaling |
Q35408800 | Casein kinase 1α-dependent feedback loop controls autophagy in RAS-driven cancers |
Q38256306 | Cellular and metabolic functions for autophagy in cancer cells |
Q26768687 | Cilia in autophagy and cancer |
Q92431789 | Colorectal cancer cells respond differentially to autophagy inhibition in vivo |
Q99406581 | Combination treatments with hydroxychloroquine and azithromycin are compatible with the therapeutic induction of anticancer immune responses |
Q96638744 | Combined deletion of Glut1 and Glut3 impairs lung adenocarcinoma growth |
Q90025843 | Comprehensive autophagy evaluation in cardiac disease models |
Q34556943 | Cyclin D1 Restrains Oncogene-Induced Autophagy by Regulating the AMPK-LKB1 Signaling Axis. |
Q35596987 | Development of an HTS-Compatible Assay for the Discovery of Ulk1 Inhibitors |
Q35068068 | Different effects of LDH-A inhibition by oxamate in non-small cell lung cancer cells |
Q35086734 | Discovery of autophagy inhibitors with antiproliferative activity in lung and pancreatic cancer cells. |
Q60956528 | Do neurogenic and cancer-induced muscle atrophy follow common or divergent paths? |
Q42576431 | Eat this, not that! How selective autophagy helps cancer cells survive |
Q36634693 | Elevated p62/SQSTM1 determines the fate of autophagy-deficient neural stem cells by increasing superoxide |
Q27009194 | Emerging strategies to effectively target autophagy in cancer |
Q53710644 | Functions of autophagy in the tumor microenvironment and cancer metastasis. |
Q26744062 | Fundamentals of cancer metabolism |
Q88688533 | Genetically Engineered Mouse Models of K-Ras-Driven Lung and Pancreatic Tumors: Validation of Therapeutic Targets |
Q26765438 | Genetics and biology of pancreatic ductal adenocarcinoma |
Q90382725 | Glucose Metabolism in Pancreatic Cancer |
Q64104124 | Glycine decarboxylase induces autophagy and is downregulated by miRNA-30d-5p in hepatocellular carcinoma |
Q52316687 | HSP90 inhibition targets autophagy and induces a CASP9-dependent resistance mechanism in NSCLC. |
Q42292319 | Honokiol Induces Apoptosis, G1 Arrest, and Autophagy in KRAS Mutant Lung Cancer Cells |
Q93010911 | Human Papillomavirus 11 Early Protein E6 Activates Autophagy by Repressing AKT/mTOR and Erk/mTOR |
Q92021279 | IKKβ slows Huntington's disease progression in R6/1 mice |
Q39446526 | IP3 Receptor-Mediated Calcium Signaling and Its Role in Autophagy in Cancer |
Q36069096 | Identification of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase as a novel autophagy regulator by high content shRNA screening. |
Q90217131 | Identification of Eph receptor signaling as a regulator of autophagy and a therapeutic target in colorectal carcinoma |
Q37687104 | Identification of breast cancer cell subtypes sensitive to ATG4B inhibition. |
Q38329422 | Integrating autophagy and metabolism in cancer |
Q47301172 | Interplay of autophagy, receptor tyrosine kinase signalling and endocytic trafficking |
Q92753000 | Involvement of Actin in Autophagy and Autophagy-Dependent Multidrug Resistance in Cancer |
Q38860336 | KLF4-SQSTM1/p62-associated prosurvival autophagy contributes to carfilzomib resistance in multiple myeloma models |
Q57025342 | LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance |
Q38624923 | LC3A Silencing Hinders Aggresome Vimentin Cage Clearance in Primary Choroid Plexus Carcinoma |
Q100696512 | LncRNA SNHG11 promotes gastric cancer progression by activating Wnt/β-catenin pathway and oncogenic autophagy |
Q92778431 | Loss of autophagy in chondrocytes causes severe growth retardation |
Q62746316 | MAP kinase and autophagy pathways cooperate to maintain RAS mutant cancer cell survival |
Q36459468 | Macroautophagy is dispensable for growth of KRAS mutant tumors and chloroquine efficacy |
Q89893362 | Macropinocytosis Renders a Subset of Pancreatic Tumor Cells Resistant to mTOR Inhibition |
Q60952270 | Macropinocytosis and autophagy crosstalk in nutrient scavenging |
Q38763163 | Measuring Autophagy in the Context of Cancer |
Q57269850 | Mechanism and medical implications of mammalian autophagy |
Q92875471 | Mechanisms and Pathophysiological Roles of the ATG8 Conjugation Machinery |
Q36840116 | Mechanisms of Selective Autophagy in Normal Physiology and Cancer |
Q49544329 | Metabolic Changes During Cancer Cachexia Pathogenesis. |
Q38423050 | Metabolic Dependencies in RAS-Driven Cancers |
Q34452291 | Metabolic control of autophagy |
Q60952272 | Metabolic functions of macropinocytosis |
Q28086940 | Metabolic pathways promoting cancer cell survival and growth |
Q93042179 | Metabolic regulation of cell growth and proliferation |
Q38930811 | Metabolic scavenging by cancer cells: when the going gets tough, the tough keep eating |
Q41693854 | Microenvironmental autophagy promotes tumour growth |
Q38760551 | Mitochondria and Cancer |
Q49708541 | Mitochondrial Dysfunction: A Novel Potential Driver of Epithelial-to-Mesenchymal Transition in Cancer. |
Q37536809 | Mitochondrial clearance by the STK38 kinase supports oncogenic Ras-induced cell transformation |
Q38622790 | Modeling K-Ras-driven lung adenocarcinoma in mice: preclinical validation of therapeutic targets |
Q42660088 | Mouse models address key concerns regarding autophagy inhibition in cancer therapy |
Q26739932 | Multiple Roles of the Small GTPase Rab7 |
Q88582817 | NRF2 and the Hallmarks of Cancer |
Q64083375 | Non‑covalent proteasome inhibitor PI‑1840 induces apoptosis and autophagy in osteosarcoma cells |
Q98225530 | Nrf2 promotes esophageal squamous cell carcinoma (ESCC) resistance to radiotherapy through the CaMKIIα-associated activation of autophagy |
Q35036374 | Nutrient-sensing mechanisms and pathways. |
Q92259393 | On ATG4B as Drug Target for Treatment of Solid Tumours-The Knowns and the Unknowns |
Q91936391 | Oncogenic KIT mutations induce STAT3-dependent autophagy to support cell proliferation in acute myeloid leukemia |
Q38830428 | Oxidative pentose phosphate pathway inhibition is a key determinant of antimalarial induced cancer cell death |
Q26780372 | Pancreatic Cancer Metabolism: Breaking It Down to Build It Back Up |
Q54979740 | Phosphatidylinositol-5-Phosphate 4-Kinases Regulate Cellular Lipid Metabolism By Facilitating Autophagy. |
Q36884215 | Proteoglycans regulate autophagy via outside-in signaling: an emerging new concept |
Q97526399 | Proteomics reveals a therapeutic vulnerability via the combined blockade of APE1 and autophagy in lung cancer A549 cells |
Q41973618 | Q&A: targeting autophagy in cancer-a new therapeutic? |
Q38586434 | Recent insights into cell death and autophagy. |
Q37343004 | Recent insights into the function of autophagy in cancer |
Q92187422 | Regulation of Apoptosis by Autophagy to Enhance Cancer Therapy |
Q42516352 | Regulation of Glycolytic Metabolism by Autophagy in Liver Cancer Involves Selective Autophagic Degradation of HK2 (hexokinase 2). |
Q97587570 | Ribosome profiling reveals a functional role for autophagy in mRNA translational control |
Q38768455 | Role of ATG10 expression quantitative trait loci in non-small cell lung cancer survival |
Q92500806 | Role of tumor and host autophagy in cancer metabolism |
Q58737053 | Roles for the IKK-Related Kinases TBK1 and IKKε in Cancer |
Q60923323 | Selective Autophagy Regulates Cell Cycle in Cancer Therapy |
Q37736687 | Sesamol Induces Human Hepatocellular Carcinoma Cells Apoptosis by Impairing Mitochondrial Function and Suppressing Autophagy |
Q90090983 | Silencing of circRACGAP1 sensitizes gastric cancer cells to apatinib via modulating autophagy by targeting miR-3657 and ATG7 |
Q37628979 | Simultaneous activation and inhibition of autophagy sensitizes cancer cells to chemotherapy |
Q91738617 | Strategies For Targeting Chronic Myeloid Leukaemia Stem Cells |
Q41595099 | Suppression of autophagy impedes glioblastoma development and induces senescence |
Q50137656 | System-wide Benefits of Intermeal Fasting by Autophagy. |
Q35338389 | Targeting Autophagy in BRAF-Mutant Tumors |
Q41912265 | Targeting autophagy in cancer |
Q88406511 | Targeting autophagy in cancer |
Q91480154 | Targeting autophagy using natural compounds for cancer prevention and therapy |
Q92861783 | Targeting of early endosomes by autophagy facilitates EGFR recycling and signalling |
Q91304849 | Targeting quiescent leukemic stem cells using second generation autophagy inhibitors |
Q92711500 | Temporal inhibition of autophagy reveals segmental reversal of ageing with increased cancer risk |
Q36654206 | The Genomic Landscape of Renal Oncocytoma Identifies a Metabolic Barrier to Tumorigenesis |
Q52631846 | The RNA binding protein tristetraprolin down-regulates autophagy in lung adenocarcinoma cells. |
Q92230700 | The Role of Autophagy in Cancer |
Q58610550 | The Roles of Autophagy in Cancer |
Q90745502 | The Tripartite Nexus: Autophagy, Cancer, and Tripartite Motif-Containing Protein Family Members |
Q52687668 | The autophagic network and cancer. |
Q38612793 | The greedy nature of mutant RAS: a boon for drug discovery targeting cancer metabolism? |
Q36111784 | The marine n-3 PUFA DHA evokes cytoprotection against oxidative stress and protein misfolding by inducing autophagy and NFE2L2 in human retinal pigment epithelial cells |
Q35242506 | The role for autophagy in cancer |
Q41339988 | The role of autophagy in hepatocellular carcinoma: friend or foe. |
Q28078117 | Therapeutic Targeting of Autophagy |
Q91387223 | Therapeutic modulation of autophagy: which disease comes first? |
Q49886970 | To be or not to be cell autonomous? Autophagy says both |
Q92487257 | Transcriptional regulation of autophagy-lysosomal pathway in cancer |
Q44930465 | Transcriptional regulation of core autophagy and lysosomal genes by the androgen receptor promotes prostate cancer progression. |
Q49522804 | Ubiquitin-Specific Protease 14 Negatively Regulates Toll-Like Receptor 4-Mediated Signaling and Autophagy Induction by Inhibiting Ubiquitination of TAK1-Binding Protein 2 and Beclin 1. |
Q38865384 | Upregulation of ATG3 contributes to autophagy induced by the detachment of intestinal epithelial cells from the extracellular matrix, but promotes autophagy-independent apoptosis of the attached cells |
Q38929715 | Using enhanced-mitophagy to measure autophagic flux. |
Q38710573 | Verapamil treatment induces cytoprotective autophagy by modulating cellular metabolism |
Q92822477 | Watch What You (Self-) Eat: Autophagic Mechanisms that Modulate Metabolism |
Q39041227 | Why autophagy is good for retinal ganglion cells? |
Q91861939 | [Tristetraprolin inhibits autophagy in cultured lung cancer cells via the nuclear factor-κB pathway] |
Q38769519 | βIII-Tubulin alters glucose metabolism and stress response signaling to promote cell survival and proliferation in glucose-starved non-small cell lung cancer cells |
Search more.