Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases

scientific article

Non-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases is …
instance of (P31):
meta-analysisQ815382
scholarly articleQ13442814

External links are
P356DOI10.1093/RHEUMATOLOGY/KEP470
P932PMC publication ID2909799
P698PubMed publication ID20338887
P5875ResearchGate publication ID42589011

P50authorKoichi MatsudaQ40066157
Adriana Rojas-VillarragaQ54536996
Juan-Manuel AnayaQ37366533
P2093author name stringXiaoxia Qian
Nan Shen
Swapan K Nath
Xana Kim-Howard
Gabriel J Tobón
Amit K Maiti
Parvathi Viswanathan
Carlos Cañas
Alejandra C Cherñavsky
Laura Guillén
Celi Sun
P2860cites workPolymorphisms in the tyrosine kinase 2 and interferon regulatory factor 5 genes are associated with systemic lupus erythematosusQ24530690
Replication of putative candidate-gene associations with rheumatoid arthritis in >4,000 samples from North America and Sweden: association of susceptibility with PTPN22, CTLA4, and PADI4Q24538382
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controlsQ24550675
Shared and distinct genetic variants in type 1 diabetes and celiac diseaseQ24623113
The expanding genetic overlap between multiple sclerosis and type I diabetesQ24642348
Robust associations of four new chromosome regions from genome-wide analyses of type 1 diabetesQ24652324
PLINK: a tool set for whole-genome association and population-based linkage analysesQ24677407
The american rheumatism association 1987 revised criteria for the classification of rheumatoid arthritisQ27860872
A common haplotype of interferon regulatory factor 5 (IRF5) regulates splicing and expression and is associated with increased risk of systemic lupus erythematosusQ28236839
Recent progress in rheumatoid arthritis genetics: one step towards improved patient careQ37443734
Multiple polymorphisms in the TNFAIP3 region are independently associated with systemic lupus erythematosusQ37498799
CD226 is specifically expressed on the surface of Th1 cells and regulates their expansion and effector functionsQ40395266
Novel association of the CD226 (DNAM-1) Gly307Ser polymorphism in Wegener's granulomatosis and confirmation for multiple sclerosis in German patientsQ44454450
Different genetic effects of interferon regulatory factor 5 (IRF5) polymorphisms on systemic lupus erythematosus in a Korean population.Q46022059
Tumor necrosis factor-alpha is a common genetic risk factor for asthma, juvenile rheumatoid arthritis, and systemic lupus erythematosus in a Mexican pediatric populationQ47694591
Association of a functional polymorphism in the IRF5 region with systemic sclerosis in a Japanese populationQ47696929
Bcl-2 antagonist killer 1 (BAK1) polymorphisms influence the risk of developing autoimmune rheumatic diseases in women.Q51771654
Haplotype analysis revealed no association between the PTPN22 gene and RA in a Japanese population.Q51941868
Familial clustering of autoimmune diseases in patients with type 1 diabetes mellitusQ56452893
Analysis of 17 autoimmune disease-associated variants in type 1 diabetes identifies 6q23/TNFAIP3 as a susceptibility locusQ56591809
Association of a haplotype in the promoter region of the interferon regulatory factor 5 gene with rheumatoid arthritisQ57224610
A nonsynonymous functional variant in integrin-αM (encoded by ITGAM) is associated with systemic lupus erythematosusQ57329856
Polymorphisms and phyletic relationships of the Paisa community from Antioquia (Colombia)Q71769227
The CD226 gene in susceptibility of type 1 diabetesQ84275899
A missense single-nucleotide polymorphism in a gene encoding a protein tyrosine phosphatase (PTPN22) is associated with rheumatoid arthritisQ28267921
Genetic association of the R620W polymorphism of protein tyrosine phosphatase PTPN22 with human SLE.Q28273794
Gluten, major histocompatibility complex, and the small intestine. A molecular and immunobiologic approach to the spectrum of gluten sensitivity ('celiac sprue')Q28286857
Association of the single nucleotide polymorphism C1858T of the PTPN22 gene with type 1 diabetesQ28300110
CD226 expression deficiency causes high sensitivity to apoptosis in NK T cells from patients with systemic lupus erythematosusQ28303427
Genetic variants near TNFAIP3 on 6q23 are associated with systemic lupus erythematosusQ28924381
The 1982 revised criteria for the classification of systemic lupus erythematosusQ29547225
Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosusQ29614922
Joint analysis is more efficient than replication-based analysis for two-stage genome-wide association studiesQ29614926
Catmap: case-control and TDT meta-analysis packageQ33321698
Defining the role of the MHC in autoimmunity: a review and pooled analysisQ33330857
Replication of recently identified associated single-nucleotide polymorphisms from six autoimmune diseases in Genetic Analysis Workshop 16 rheumatoid arthritis dataQ33519292
Classification criteria for Sjögren's syndrome: a revised version of the European criteria proposed by the American-European Consensus GroupQ34523084
Evaluation of imputation-based association in and around the integrin-alpha-M (ITGAM) gene and replication of robust association between a non-synonymous functional variant within ITGAM and systemic lupus erythematosus (SLE).Q34917266
The PTPN22 C1858T functional polymorphism and autoimmune diseases--a meta-analysisQ36499626
STAT4 and the risk of rheumatoid arthritis and systemic lupus erythematosusQ37070948
CD226 Gly307Ser association with multiple autoimmune diseasesQ37083069
Two independent alleles at 6q23 associated with risk of rheumatoid arthritisQ37120830
Rheumatoid arthritis association at 6q23.Q37172071
Autoimmune diseases: insights from genome-wide association studiesQ37292877
P433issue7
P304page(s)1239-1244
P577publication date2010-03-24
P1433published inRheumatologyQ7320492
P1476titleNon-synonymous variant (Gly307Ser) in CD226 is associated with susceptibility to multiple autoimmune diseases
P478volume49

Reverse relations

cites work (P2860)
Q36245847A multicenter study confirms CD226 gene association with systemic sclerosis-related pulmonary fibrosis
Q48271582Association between CD266 polymorphism and soluble levels in rheumatoid arthritis: Relationship with clinical activity.
Q57330536Association between the CD226 rs763361 polymorphism and susceptibility to autoimmune diseases: a meta-analysis
Q54526765Association of the CD226 single nucleotide polymorphism with systemic lupus erythematosus in the Chinese Han population
Q34465877Balancing natural killer cell activation through paired receptors
Q26782799Beyond CTLA-4 and PD-1, the Generation Z of Negative Checkpoint Regulators
Q36010404CD226 gene polymorphisms are associated with non-small-cell lung cancer in the Chinese Han population
Q37441905CD226 rs763361 (Gly307Ser) polymorphism is associated with susceptibility to rheumatoid arthritis in Zahedan, southeast Iran
Q33661286CD226 rs763361 is associated with the susceptibility to type 1 diabetes and greater frequency of GAD65 autoantibody in a Brazilian cohort
Q33731047Cancer immunotherapy by targeting immune checkpoints: mechanism of T cell dysfunction in cancer immunity and new therapeutic targets
Q39160992Co-inhibitory blockade while preserving tolerance: checkpoint inhibitors for glioblastoma
Q30716850DNAM-1 control of natural killer cells functions through nectin and nectin-like proteins
Q35207467Evaluation of 19 autoimmune disease-associated loci with rheumatoid arthritis in a Colombian population: evidence for replication and gene-gene interaction
Q58575859Expression of the Inhibitory Receptor TIGIT Is Up-Regulated Specifically on NK Cells With CD226 Activating Receptor From HIV-Infected Individuals
Q52676482Functional Anti-TIGIT Antibodies Regulate Development of Autoimmunity and Antitumor Immunity.
Q36625351Gene network analysis of small molecules with autoimmune disease associated genes predicts a novel strategy for drug efficacy
Q47647361Gene-gene interaction between CD40 and CD226 gene on systemic lupus erythematosus in the Chinese Han population
Q37958780Genetics of systemic sclerosis: an update
Q93126204Helios but not CD226, TIGIT and Foxp3 is a Potential Marker for CD4+ Treg Cells in Patients with Rheumatoid Arthritis
Q27316407High-density genotyping of immune-related loci identifies new SLE risk variants in individuals with Asian ancestry
Q36102137Human herpesviridae methods of natural killer cell evasion
Q38020961Immune checkpoints in central nervous system autoimmunity.
Q38837469Lag-3, Tim-3, and TIGIT: Co-inhibitory Receptors with Specialized Functions in Immune Regulation.
Q43146199Targeting CD226/DNAX accessory molecule-1 (DNAM-1) in collagen-induced arthritis mouse models
Q44839338The CD226 gene in susceptibility of rheumatoid arthritis in the Chinese Han population
Q56452307The Multiple Autoimmune Syndromes. A Clue for the Autoimmune Tautology
Q92890914The yin and yang of co-inhibitory receptors: toward anti-tumor immunity without autoimmunity
Q28512622Vstm3 is a member of the CD28 family and an important modulator of T-cell function

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