parD toxin-antitoxin system of plasmid R1--basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems.

scientific article

parD toxin-antitoxin system of plasmid R1--basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems. is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1111/J.1742-4658.2010.07722.X
P698PubMed publication ID20569269
P5875ResearchGate publication ID44693696

P50authorElizabeth Diago-NavarroQ82662250
Rolf BoelensQ28468897
P2093author name stringAna J Muñoz-Gómez
Ramón Díaz-Orejas
Marc Lemonnier
Monique B Kamphuis
Juan López-Villarejo
Ana M Hernandez-Arriaga
P2860cites workBacterial toxin-antitoxin systems: more than selfish entities?Q21145003
Bacterial programmed cell death and multicellular behavior in bacteriaQ21145260
New connections in the prokaryotic toxin-antitoxin network: relationship with the eukaryotic nonsense-mediated RNA decay systemQ21194875
Prokaryotic DNA segregation by an actin-like filamentQ24536852
Kid cleaves specific mRNAs at UUACU sites to rescue the copy number of plasmid R1Q24536942
Toxin-antitoxin modules may regulate synthesis of macromolecules during nutritional stressQ24548999
Mini-F plasmid genes that couple host cell division to plasmid proliferationQ24594938
An Escherichia coli chromosomal "addiction module" regulated by guanosine [corrected] 3',5'-bispyrophosphate: a model for programmed bacterial cell deathQ24607301
Unique type of plasmid maintenance function: postsegregational killing of plasmid-free cellsQ24630262
Chromosomal toxin-antitoxin systems may act as antiaddiction modulesQ24646891
Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipBQ24651429
What is the benefit to Escherichia coli of having multiple toxin-antitoxin systems in its genome?Q24675694
Postsegregational killing does not increase plasmid stability but acts to mediate the exclusion of competing plasmidsQ24679732
Structural and functional analysis of the kid toxin protein from E. coli plasmid R1Q27639783
Interactions between the toxin Kid of the bacterial parD system and the antitoxins Kis and MazE.Q53579152
GATEWAY recombinational cloning: application to the cloning of large numbers of open reading frames or ORFeomes.Q53901952
The F plasmid CcdB protein induces efficient ATP-dependent DNA cleavage by gyrase.Q54223810
Isolation and characterization of a conditional replication mutant of the antibiotic resistance factor R1 affected in the gene of the replication protein repA.Q54354534
Messenger RNA interferase RelE controls relBE transcription by conditional cooperativity.Q54421444
Single protein production in living cells facilitated by an mRNA interferase.Q54487510
RelE toxins from bacteria and Archaea cleave mRNAs on translating ribosomes, which are rescued by tmRNA.Q54524054
Rapid induction and reversal of a bacteriostatic condition by controlled expression of toxins and antitoxins.Q54541820
Translational coupling and limited degradation of a polycistronic messenger modulate differential gene expression in the parD stability system of plasmid R1.Q54603721
Kid, a small protein of the parD stability system of plasmid R1, is an inhibitor of DNA replication acting at the initiation of DNA synthesis.Q54614008
Protection of coliphage lambda O initiator protein from proteolysis in the assembly of the replication complex in vivo.Q54617021
Lon-dependent proteolysis of CcdA is the key control for activation of CcdB in plasmid-free segregant bacteria.Q54639171
The kis and kid genes of the parD maintenance system of plasmid R1 form an operon that is autoregulated at the level of transcription by the co-ordinated action of the Kis and Kid proteins.Q54689585
Structural and functional comparison between the stability systems ParD of plasmid R1 and Ccd of plasmid F.Q54699683
Crystal structure of the MazE/MazF complex: molecular bases of antidote-toxin recognitionQ27641078
Crystal structure of the met repressor-operator complex at 2.8 A resolution reveals DNA recognition by beta-strandsQ27642147
The Structural Basis for mRNA Recognition and Cleavage by the Ribosome-Dependent Endonuclease RelEQ27646567
The solution structure of ParD, the antidote of the ParDE toxin-antitoxin module, provides the structural basis for DNA and toxin bindingQ27646891
Crystal structure of Mycobacterium tuberculosis YefM antitoxin reveals that it is not an intrinsically unstructured proteinQ27652155
Inhibitory Mechanism of Escherichia coli RelE-RelB Toxin-Antitoxin Module Involves a Helix Displacement Near an mRNA Interferase Active SiteQ27654200
Rejuvenation of CcdB-poisoned gyrase by an intrinsically disordered protein domainQ27656829
A Conserved Mode of Protein Recognition and Binding in a ParD−ParE Toxin−Antitoxin ComplexQ27659672
DNA recognition by beta-sheets in the Arc repressor-operator crystal structureQ27730947
Crystal structure of CcdB, a topoisomerase poison from E. coliQ27766729
MOLMOL: a program for display and analysis of macromolecular structuresQ27860873
Addiction modules and programmed cell death and antideath in bacterial culturesQ28146167
Toxins-antitoxins: plasmid maintenance, programmed cell death, and cell cycle arrestQ28206549
Antisense RNA-regulated programmed cell deathQ28259967
RNA antitoxinsQ28294158
Prokaryotic toxin-antitoxin stress response lociQ29615335
Characterization of ChpBK, an mRNA interferase from Escherichia coliQ30852783
Development without germ cells: the role of the germ line in zebrafish sex differentiation.Q30856433
Release of peptide promoted by the GGQ motif of class 1 release factors regulates the GTPase activity of RF3.Q30868692
The YefM antitoxin defines a family of natively unfolded proteins: implications as a novel antibacterial targetQ30886064
Structural basis for nucleic acid and toxin recognition of the bacterial antitoxin CcdA.Q31063061
Comprehensive comparative-genomic analysis of type 2 toxin-antitoxin systems and related mobile stress response systems in prokaryotesQ33459528
Cell killing by the F plasmid CcdB protein involves poisoning of DNA-topoisomerase II complexesQ33969008
MazF Cleaves Cellular mRNAs Specifically at ACA to Block Protein Synthesis in Escherichia coliQ33973437
Bacterial toxin-antitoxin gene system as containment control in yeast cellsQ33988395
MazG -- a regulator of programmed cell death in Escherichia coliQ33992667
MazF, an mRNA interferase, mediates programmed cell death during multicellular Myxococcus developmentQ34009374
The art of selective killing: plasmid toxin/antitoxin systems and their technological applicationsQ34013680
Positive-selection vectors using the F plasmid ccdB killer geneQ34059638
The ratio between CcdA and CcdB modulates the transcriptional repression of the ccd poison-antidote systemQ34083974
Identification of components of a new stability system of plasmid R1, ParD, that is close to the origin of replication of this plasmidQ34174283
A linear pentapeptide is a quorum-sensing factor required for mazEF-mediated cell death in Escherichia coli.Q46930277
PIN domains in nonsense-mediated mRNA decay and RNAiQ47069110
Control of segregation of chromosomal DNA by sex factor F in Escherichia coli. Mutants of DNA gyrase subunit A suppress letD (ccdB) product growth inhibitionQ48174226
Analysis of plasmid genome evolution based on nucleotide-sequence comparison of two related plasmids of Escherichia coliQ48405680
Structure of Arc repressor in solution: evidence for a family of beta-sheet DNA-binding proteins.Q50464242
Recognition of the intrinsically flexible addiction antidote MazE by a dromedary single domain antibody fragment. Structure, thermodynamics of binding, stability, and influence on interactions with DNA.Q52282024
Molecular basis of gyrase poisoning by the addiction toxin CcdB.Q52287398
A mutagenic analysis of the RNase mechanism of the bacterial Kid toxin by mass spectrometry.Q53376615
The Escherichia coli mazEF suicide module mediates thymineless deathQ34181444
Toxin-antitoxin loci as stress-response-elements: ChpAK/MazF and ChpBK cleave translated RNAs and are counteracted by tmRNA.Q34230226
Toxin-antitoxin modules as bacterial metabolic stress managersQ34463800
Shutdown decay of mRNA.Q34542254
Role of DNA replication and repair in thymineless death in Escherichia coliQ34976537
Construction of a Vibrio splendidus mutant lacking the metalloprotease gene vsm by use of a novel counterselectable suicide vectorQ35641989
Toxin-antitoxin regulation: bimodal interaction of YefM-YoeB with paired DNA palindromes exerts transcriptional autorepressionQ35646662
Plasmid R1--replication and its controlQ36274445
The extracellular death factor: physiological and genetic factors influencing its production and response in Escherichia coliQ36594594
Structure and function of bacterial kid-kis and related toxin-antitoxin systemsQ36738054
ATP-dependent degradation of CcdA by Lon protease. Effects of secondary structure and heterologous subunit interactionsQ36831491
Novel Escherichia coli RF1 mutants with decreased translation termination activity and increased sensitivity to the cytotoxic effect of the bacterial toxins Kid and RelEQ37187273
RNase II is important for A-site mRNA cleavage during ribosome pausingQ37365620
Horizontal gene transfer and the earliest stages of the evolution of lifeQ37568557
The antidote and autoregulatory functions of the F plasmid CcdA protein: a genetic and biochemical surveyQ38304603
chpA and chpB, Escherichia coli chromosomal homologs of the pem locus responsible for stable maintenance of plasmid R100Q38314758
DnaB helicase stimulates primer synthesis activity on short oligonucleotide templatesQ38316011
Interference of mRNA function by sequence-specific endoribonuclease PemK.Q38343561
A strand-passage conformation of DNA gyrase is required to allow the bacterial toxin, CcdB, to access its binding siteQ39079987
Toxin-antitoxin based transgene expression in mammalian cellsQ39556928
Regulatable killing of eukaryotic cells by the prokaryotic proteins Kid and Kis.Q39696663
The stable maintenance system pem of plasmid R100: degradation of PemI protein may allow PemK protein to inhibit cell growthQ39935070
Definition of a minimal plasmid stabilization system from the broad-host-range plasmid RK2.Q39940253
Structure and organization of hip, an operon that affects lethality due to inhibition of peptidoglycan or DNA synthesisQ39943160
Two genes, pemK and pemI, responsible for stable maintenance of resistance plasmid R100.Q39952666
Control of replication of bacterial plasmids: Genetics, molecular biology, and physiology of the plasmid R1 systemQ40112314
Programmed cell death in bacterial populationsQ40586191
The beta-ribbon DNA recognition motifQ40627901
Bacterial toxin RelE induces apoptosis in human cellsQ40730517
Broad-host-range plasmid replication: an open question.Q41172958
Cooperative tandem binding of met repressor of Escherichia coliQ41298156
Comparison of ccd of F, parDE of RP4, and parD of R1 using a novel conditional replication control system of plasmid R1.Q41654669
Conditionally lethal genes associated with bacterial plasmidsQ41655129
Interactions of Kid-Kis toxin-antitoxin complexes with the parD operator-promoter region of plasmid R1 are piloted by the Kis antitoxin and tuned by the stoichiometry of Kid-Kis oligomers.Q41811686
RNase/anti-RNase activities of the bacterial parD toxin-antitoxin systemQ42054469
Driving forces of gyrase recognition by the addiction toxin CcdB.Q42136192
Model for RNA binding and the catalytic site of the RNase Kid of the bacterial parD toxin-antitoxin system.Q42167261
Analysis of an Escherichia coli mutant strain resistant to the cell-killing function encoded by the gef gene familyQ42611510
The chromosomal relBE2 toxin-antitoxin locus of Streptococcus pneumoniae: characterization and use of a bioluminescence resonance energy transfer assay to detect toxin-antitoxin interactionQ42678581
A toxin-antitoxin module as a target for antimicrobial developmentQ43267764
The regulation of the Escherichia coli mazEF promoter involves an unusual alternating palindromeQ43509583
Non-cytotoxic variants of the Kid protein that retain their auto-regulatory activityQ44558880
Separate-component-stabilization system for protein and DNA production without the use of antibioticsQ45884103
P433issue15
P407language of work or nameEnglishQ1860
P921main subjectbiotechnologyQ7108
P304page(s)3097-3117
P577publication date2010-06-21
P1433published inFEBS JournalQ1388041
P1476titleparD toxin-antitoxin system of plasmid R1--basic contributions, biotechnological applications and relationships with closely-related toxin-antitoxin systems
P478volume277

Reverse relations

cites work (P2860)
Q21133955A common origin for the bacterial toxin-antitoxin systems parD and ccd, suggested by analyses of toxin/target and toxin/antitoxin interactions
Q27666599A processed noncoding RNA regulates an altruistic bacterial antiviral system
Q27028105Antibiotic-free selection in biotherapeutics: now and forever
Q41494477Coupling between the basic replicon and the Kis-Kid maintenance system of plasmid R1: modulation by Kis antitoxin levels and involvement in control of plasmid replication
Q35604307Expression of the Streptococcus pneumoniae yoeB chromosomal toxin gene causes cell death in the model plant Arabidopsis thaliana
Q37895333Identification of bacterial plasmids based on mobility and plasmid population biology.
Q26751512Keeping the Wolves at Bay: Antitoxins of Prokaryotic Type II Toxin-Antitoxin Systems
Q88702084Next-generation biocontainment systems for engineered organisms
Q34495366Recent advancements in toxin and antitoxin systems involved in bacterial programmed cell death
Q37576199Regulating toxin-antitoxin expression: controlled detonation of intracellular molecular timebombs
Q89878402Safety Aspects of Genetically Modified Lactic Acid Bacteria
Q46296325Structural analyses of the MazEF4 toxin-antitoxin pair in Mycobacterium tuberculosis provide evidence for a unique extracellular death factor.
Q28079157Structure, Evolution, and Functions of Bacterial Type III Toxin-Antitoxin Systems
Q38064401Toxin-antitoxin genes of the Gram-positive pathogen Streptococcus pneumoniae: so few and yet so many.

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