Kcnq1ot1: A chromatin regulatory RNA

scientific article published on February 21, 2011

Kcnq1ot1: A chromatin regulatory RNA is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1016/J.SEMCDB.2011.02.020
P953full work available online athttps://api.elsevier.com/content/article/PII:S1084952111000334?httpAccept=text/plain
https://api.elsevier.com/content/article/PII:S1084952111000334?httpAccept=text/xml
P698PubMed publication ID21345374

P2093author name stringChandrasekhar Kanduri
P2860cites workLong noncoding RNA as modular scaffold of histone modification complexesQ22065890
X-inactivation profile reveals extensive variability in X-linked gene expression in femalesQ22122481
Elongation of the Kcnq1ot1 transcript is required for genomic imprinting of neighboring genesQ24546155
An antisense RNA regulates the bidirectional silencing property of the Kcnq1 imprinting control regionQ24563030
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasisQ24607308
Kcnq1ot1/Lit1 noncoding RNA mediates transcriptional silencing by targeting to the perinucleolar regionQ24641815
A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silencedQ24672840
Functional demarcation of active and silent chromatin domains in human HOX loci by noncoding RNAsQ24673619
Long non-coding RNAs: insights into functionsQ28131764
Targeted mutation of the DNA methyltransferase gene results in embryonic lethalityQ28131773
The non-coding Air RNA is required for silencing autosomal imprinted genesQ28504980
Polycomb group proteins Ezh2 and Rnf2 direct genomic contraction and imprinted repression in early mouse embryosQ82264671
Epigenetics of imprinted long non-coding RNAsQ95822693
The Air noncoding RNA epigenetically silences transcription by targeting G9a to chromatinQ28506981
Kcnq1ot1 noncoding RNA mediates transcriptional gene silencing by interacting with Dnmt1Q28507331
Genome imprinting regulated by the mouse Polycomb group protein EedQ28510758
A developmental window of opportunity for imprinted gene silencing mediated by DNA methylation and the Kcnq1ot1 noncoding RNAQ28513982
Regional loss of imprinting and growth deficiency in mice with a targeted deletion of KvDMR1Q28589840
The Polycomb complex PRC2 and its mark in lifeQ29547358
Kcnq1ot1 antisense noncoding RNA mediates lineage-specific transcriptional silencing through chromatin-level regulationQ29614333
Long noncoding RNAs: functional surprises from the RNA worldQ29615826
The function of non-coding RNAs in genomic imprintingQ33761870
Regulatory roles of natural antisense transcriptsQ33773381
Multiple Mechanisms Regulate Imprinting of the Mouse Distal Chromosome 7 Gene ClusterQ33774256
Non-coding RNAs as regulators of embryogenesisQ33844577
Characterization of the RNA content of chromatinQ33940935
Noncoding RNA in developmentQ34014009
Domain-specific response of imprinted genes to reduced DNMT1.Q34045773
Chromosomal silencing and localization are mediated by different domains of Xist RNAQ34108304
Imprinting along the Kcnq1 domain on mouse chromosome 7 involves repressive histone methylation and recruitment of Polycomb group complexes.Q34363546
Eukaryotic regulatory RNAs: an answer to the 'genome complexity' conundrumQ34599474
Non-coding RNAs in imprinted gene clustersQ34749691
RNA meets chromatinQ36197886
Two distinct mechanisms of silencing by the KvDMR1 imprinting control regionQ36392021
G9a histone methyltransferase contributes to imprinting in the mouse placentaQ36421353
DNA methyltransferase 1o functions during preimplantation development to preclude a profound level of epigenetic variationQ37104670
The long noncoding RNA Kcnq1ot1 organises a lineage-specific nuclear domain for epigenetic gene silencingQ37201459
Lessons from X-chromosome inactivation: long ncRNA as guides and tethers to the epigenomeQ37302890
Regulation of the mammalian epigenome by long noncoding RNAs.Q37327811
The long and the short of it: RNA-directed chromatin asymmetry in mammalian X-chromosome inactivationQ37419601
Polycomb group proteins: navigators of lineage pathways led astray in cancerQ37620148
LINE-1 activity in facultative heterochromatin formation during X chromosome inactivationQ39692744
The length of the transcript encoded from the Kcnq1ot1 antisense promoter determines the degree of silencingQ40289583
NF-Y regulates the antisense promoter, bidirectional silencing, and differential epigenetic marks of the Kcnq1 imprinting control regionQ40508899
Evolution of the Beckwith-Wiedemann syndrome region in vertebratesQ40774859
Targeted disruption of the human LIT1 locus defines a putative imprinting control element playing an essential role in Beckwith-Wiedemann syndromeQ40859099
Syntenic organization of the mouse distal chromosome 7 imprinting cluster and the Beckwith-Wiedemann syndrome region in chromosome 11p15.5.Q48000452
Epigenetic dynamics of the Kcnq1 imprinted domain in the early embryoQ50644071
Partners in imprinting: noncoding RNA and polycomb group proteinsQ51946753
Imprinting on distal chromosome 7 in the placenta involves repressive histone methylation independent of DNA methylation.Q52086106
Parental origin-specific expression of Mash2 is established at the time of implantation with its imprinting mechanism highly resistant to genome-wide demethylationQ52174393
Functional insights into long antisense noncoding RNA Kcnq1ot1 mediated bidirectional silencingQ53443232
Suggestive evidence for chromosomal localization of non-coding RNA from imprinted LIT1Q81400139
P433issue4
P407language of work or nameEnglishQ1860
P921main subjectDNA methylationQ874745
gene silencingQ1431332
P304page(s)343-350
P577publication date2011-02-21
P13046publication type of scholarly workreview articleQ7318358
P1433published inSeminars in Cell & Developmental BiologyQ14330411
P1476titleKcnq1ot1: A chromatin regulatory RNA
P478volume22

Reverse relations

cites work (P2860)
Q38738529A cross-talk between DNA methylation and H3 lysine 9 dimethylation at the KvDMR1 region controls the induction of Cdkn1c in muscle cells.
Q59132581A novel cancer syndrome caused by -deficiency in the golden Syrian hamster
Q41096276APF lncRNA regulates autophagy and myocardial infarction by targeting miR-188-3p
Q37231014Biochemical Methods To Investigate lncRNA and the Influence of lncRNA:Protein Complexes on Chromatin
Q64230048Biological functions of circular RNAs and their roles in occurrence of reproduction and gynecological diseases
Q46662082CARL lncRNA inhibits anoxia-induced mitochondrial fission and apoptosis in cardiomyocytes by impairing miR-539-dependent PHB2 downregulation
Q37745367CASC2c as an unfavorable prognosis factor interacts with miR-101 to mediate astrocytoma tumorigenesis
Q26778537Cellular Response upon Stress: p57 Contribution to the Final Outcome
Q38038646Chromatin structure, epigenetic mechanisms and long‐range interactions in the human insulin locus
Q33828820Circular RNA expression profiling of human granulosa cells during maternal aging reveals novel transcripts associated with assisted reproductive technology outcomes
Q51531600Circulating 'lncRNA OTTHUMT00000387022' from monocytes as a novel biomarker for coronary artery disease
Q64249225Circulating Long Non-coding RNA ENST00000507296 Is a Prognostic Indicator in Patients with Dilated Cardiomyopathy
Q50114394Construction and analysis for differentially expressed long non-coding RNAs and MicroRNAs mediated competing endogenous RNA network in colon cancer.
Q34320111Differentiation-Driven Nucleolar Association of the Mouse Imprinted Kcnq1 Locus
Q57262835Evolution of Eukaryotic Chromatin Proteins and Transcription Factors
Q38364072Experience-sensitive epigenetic mechanisms, developmental plasticity, and the biological embedding of chronic disease risk
Q30491427Exploring the molecular pathogenesis and biomarkers of high risk oral premalignant lesions on the basis of long noncoding RNA expression profiling by serial analysis of gene expression
Q37626818Expression signature of lncRNAs and their potential roles in cardiac fibrosis of post-infarct mice
Q38162737Functional insights into the role of nuclear-retained long noncoding RNAs in gene expression control in mammalian cells
Q90070094Genome-wide analysis and functional prediction of the estrogen-regulated transcriptional response in the mouse uterus†
Q33742695Genome-wide discovery and characterization of maize long non-coding RNAs.
Q89597780Human Long Noncoding RNA Interactome: Detection, Characterization and Function
Q31032840Human cancer long non-coding RNA transcriptomes
Q92480202Integrated analysis of lncRNA-miRNA-mRNA ceRNA network in squamous cell carcinoma of tongue
Q91827366KCNQ1OT1/miR-217/ZEB1 feedback loop facilitates cell migration and epithelial-mesenchymal transition in colorectal cancer
Q57461754Knockdown of lncRNA KCNQ1OT1 suppresses the adipogenic and osteogenic differentiation of tendon stem cell via downregulating miR-138 target genes PPARγand RUNX2
Q91977478LncRNA KCNQ1OT1 contributes to oxygen-glucose-deprivation/reoxygenation-induced injury via sponging miR-9 in cultured neurons to regulate MMP8
Q91291214LncRNA KCNQ1OT1 promoted BMP2 expression to regulate osteogenic differentiation by sponging miRNA-214
Q94593353LncRNA KCNQ1OT1 promotes cell proliferation, migration and invasion via regulating miR-129-5p/JAG1 axis in non-small cell lung cancer
Q104134871LncRNA kcnq1ot1 promotes lipid accumulation and accelerates atherosclerosis via functioning as a ceRNA through the miR-452-3p/HDAC3/ABCA1 axis
Q47942929Long Noncoding RNA: Genome Organization and Mechanism of Action
Q37982678Long Noncoding RNAs: Insights from Biological Features and Functions to Diseases.
Q38700234Long non-coding RNA MSTO2P promotes the proliferation and colony formation in gastric cancer by indirectly regulating miR-335 expression
Q26999388Long non-coding RNA-dependent transcriptional regulation in neuronal development and disease
Q36208103Long non-coding RNAs and cancer: a new frontier of translational research?
Q38961358Long non-coding RNAs in human early embryonic development and their potential in ART.
Q37441308Long noncoding RNA-mediated intrachromosomal interactions promote imprinting at the Kcnq1 locus.
Q38208799Long noncoding RNA: significance and potential in skin biology
Q35747814Long noncoding RNAs in development and cancer: potential biomarkers and therapeutic targets
Q33649809Long noncoding RNAs in imprinting and X chromosome inactivation
Q26824697Long noncoding RNAs-related diseases, cancers, and drugs
Q38200054Long noncoding RNAs: emerging stars in gene regulation, epigenetics and human disease.
Q35212300MDRL lncRNA regulates the processing of miR-484 primary transcript by targeting miR-361.
Q38849879MEG3 long noncoding RNA regulates the TGF-β pathway genes through formation of RNA-DNA triplex structures.
Q38159961Maintenance of epigenetic information: a noncoding RNA perspective
Q21131260Molecular evolution of the non-coding eosinophil granule ontogeny transcript
Q26823935Nuclear lncRNAs as epigenetic regulators-beyond skepticism
Q54942692Overexpression of long non-coding RNA KCNQ1OT1 is related to good prognosis via inhibiting cell proliferation in non-small cell lung cancer.
Q34554885Psip1/p52 regulates posterior Hoxa genes through activation of lncRNA Hottip
Q37158599Regulation of chromatin structure by long noncoding RNAs: focus on natural antisense transcripts
Q38382701Regulation of functional KCNQ1OT1 lncRNA by β-catenin
Q39172425Role of DNA methylation in imprinting disorders: an updated review
Q47947947Role of noncoding RNAs in regulation of cardiac cell death and cardiovascular diseases
Q39123568Spatial localization of genes determined by intranuclear DNA fragmentation with the fusion proteins lamin KRED and histone KRED und visible light
Q35605181The KCNQ1OT1 imprinting control region and non-coding RNA: new properties derived from the study of Beckwith-Wiedemann syndrome and Silver-Russell syndrome cases
Q37873983The central role of RNA in human development and cognition
Q38256144The functional role of long non-coding RNAs and epigenetics
Q46675216The lncRNA PDIA3P Interacts with miR-185-5p to Modulate Oral Squamous Cell Carcinoma Progression by Targeting Cyclin D2.
Q61447715The long non-coding RNA Kcnq1ot1 controls maternal p57 expression in muscle cells by promoting H3K27me3 accumulation to an intragenic MyoD-binding region
Q41985560The long noncoding RNA NRF regulates programmed necrosis and myocardial injury during ischemia and reperfusion by targeting miR-873.
Q38116919The role of noncoding RNAs in chromatin regulation during differentiation
Q34521385Transcriptional gene silencing in humans
Q47417752Valsartan regulates TGF-β/Smads and TGF-β/p38 pathways through lncRNA CHRF to improve doxorubicin-induced heart failure
Q52581968lincRNA-Cox2 regulates NLRP3 inflammasome and autophagy mediated neuroinflammation.
Q37163179miR-489 inhibits silica-induced pulmonary fibrosis by targeting MyD88 and Smad3 and is negatively regulated by lncRNA CHRF.

Search more.