Adenosine and bone metabolism

scientific article

Adenosine and bone metabolism is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/J.TEM.2013.02.001
P932PMC publication ID3669669
P698PubMed publication ID23499155

P2093author name stringBruce N Cronstein
Aránzazu Mediero
P2860cites workCGS 21680, an agonist of the adenosine (A2A) receptor, reduces progression of murine type II collagen-induced arthritisQ84566841
Polydeoxyribonucleotide reduces cytokine production and the severity of collagen-induced arthritis by stimulation of adenosine A(₂A) receptorQ84571966
Protein kinase a mediated anti-inflammatory effects exerted by adenosine treatment in mouse chondrocytes stimulated with IL-1βQ85268787
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis 1Q22306225
Osteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
Molecular action of methotrexate in inflammatory diseasesQ24534771
The physiological activity of adenine compounds with especial reference to their action upon the mammalian heartQ24540404
RANK is essential for osteoclast and lymph node developmentQ24598872
Adenosine receptors as therapeutic targetsQ24632095
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
RANKL Employs Distinct Binding Modes to Engage RANK and the Osteoprotegerin Decoy ReceptorQ27674275
Modulation of osteoclast differentiation and function by the new members of the tumor necrosis factor receptor and ligand familiesQ28137631
Blockade of the pore-forming P2X7 receptor inhibits formation of multinucleated human osteoclasts in vitroQ28188795
Osteoimmunology: shared mechanisms and crosstalk between the immune and bone systemsQ28294477
Molecular determinants of P2Y2 nucleotide receptor function: implications for proliferative and inflammatory pathways in astrocytesQ30160213
Comparison of the potency of adenosine as an agonist at human adenosine receptors expressed in Chinese hamster ovary cellsQ32065053
Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout miceQ33783389
The antiinflammatory mechanism of methotrexate. Increased adenosine release at inflamed sites diminishes leukocyte accumulation in an in vivo model of inflammation.Q33909650
Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function.Q33919462
Pharmacology of cloned P2X receptorsQ33932194
Purinergic signalling and bone remodelling.Q34021414
A2B adenosine receptor promotes mesenchymal stem cell differentiation to osteoblasts and bone formation in vivoQ34031056
P2 purinergic receptors: modulation of cell function and therapeutic potentialQ34084722
Adenosine regulates via two different types of receptors, the accumulation of cyclic AMP in cultured brain cellsQ34660775
Subclasses of external adenosine receptorsQ34661950
Adenosine A2A receptors play an active role in mouse bone marrow-derived mesenchymal stem cell development.Q34686068
International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an updateQ34701303
Regulation of bone resorption and formation by purines and pyrimidinesQ35161577
Signalling from adenosine receptors to mitogen-activated protein kinasesQ35166514
CD73-generated adenosine promotes osteoblast differentiationQ35612746
Pathologic findings in adenosine deaminase-deficient severe combined immunodeficiency. I. Kidney, adrenal, and chondro-osseous tissue alterationsQ35835243
Adenosine A(2A) receptor ligation inhibits osteoclast formation.Q35951939
Cellular distribution and functions of P2 receptor subtypes in different systemsQ35952737
Adenosine A1 receptor regulates osteoclast formation by altering TRAF6/TAK1 signaling.Q35953968
Adenosine A2A receptor activation prevents wear particle-induced osteolysisQ36067491
Overview of the P2 receptorsQ36106314
Purine and pyrimidine receptorsQ36765468
The bone microenvironment in metastasis; what is special about bone?Q37028803
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Bone as an endocrine organ.Q37527342
Adenosine receptors as drug targetsQ37691817
Osteoblast physiology in normal and pathological conditionsQ37814193
Functional selectivity of adenosine receptor ligandsQ37872220
Purinergic signalling: Its unpopular beginning, its acceptance and its exciting futureQ37975129
Is there a basis for distinguishing two types of P2-purinoceptor?Q39497248
Contrasting effects of A1 and A2b adenosine receptors on adipogenesisQ39512378
Adenosine inhibition of lipopolysaccharide-induced interleukin-6 secretion by the osteoblastic cell line MG-63.Q40092493
Characterization of adenosine receptors in bovine chondrocytes and fibroblast-like synoviocytes exposed to low frequency low energy pulsed electromagnetic fieldsQ40183574
Hydrogen peroxide-induced oxidative stress in MC3T3-E1 cells: The effects of glutamate and protection by purinesQ40292346
The role of adenosine in chondrocyte death in murine osteoarthritis and in a murine chondrocyte cell lineQ40323790
Methotrexate (MTX) inhibits osteoblastic differentiation in vitro: possible mechanism of MTX osteopathy.Q40821151
ATP and adenosine act as a mitogen for osteoblast-like cells (MC3T3-E1).Q42816768
Adenosine nucleotides acting at the human P2Y1 receptor stimulate mitogen-activated protein kinases and induce apoptosisQ43559278
Effects of an adenosine kinase inhibitor and an adenosine deaminase inhibitor on accumulation of extracellular adenosine by equine articular chondrocytesQ43590899
Chondrocytes respond to adenosine via A(2)receptors and activity is potentiated by an adenosine deaminase inhibitor and a phosphodiesterase inhibitorQ43857601
Molecular pathways: osteoclast-dependent and osteoclast-independent roles of the RANKL/RANK/OPG pathway in tumorigenesis and metastasisQ44486779
Endogenously produced adenosine regulates articular cartilage matrix homeostasis: enzymatic depletion of adenosine stimulates matrix degradationQ44849347
Inhibition of adenosine kinase attenuates interleukin-1- and lipopolysaccharide-induced alterations in articular cartilage metabolismQ45280275
Identification of proteins secreted by human osteoblastic cells in cultureQ46128068
Adenosine receptor subtype expression and activation influence the differentiation of mesenchymal stem cells to osteoblasts and adipocytesQ46293817
Purinergic receptorsQ46382093
Human osteoblast precursors produce extracellular adenosine, which modulates their secretion of IL-6 and osteoprotegerinQ46898246
The stimulation of adenosine 2A receptor reduces inflammatory response in mouse articular chondrocytes treated with hyaluronan oligosaccharides.Q47384513
Adenosine abolishes MTX-induced suppression of osteoclastogenesis and inflammatory bone destruction in adjuvant-induced arthritisQ50115228
Purinergic transmitters inhibit bone formation by cultured osteoblasts.Q52192188
Adenosine inhibits macrophage colony-stimulating factor-dependent proliferation of macrophages through the induction of p27kip-1 expression.Q52536557
P2X7 receptor drives osteoclast fusion by increasing the extracellular adenosine concentration.Q54620269
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
On the role of subtype selective adenosine receptor agonists during proliferation and osteogenic differentiation of human primary bone marrow stromal cellsQ59673298
Neurotransmitter regulation of cytosolic calcium in osteoblast-like bone cellsQ69358248
Characterization of adenosine receptors in bone. Studies on the effect of adenosine analogues on cyclic AMP formation and bone resorption in cultured mouse calvariaQ69810732
Adenosine A1 receptor promotion of multinucleated giant cell formation by human monocytes: A mechanism for methotrexate-induced nodulosis in rheumatoid arthritisQ73491938
Inverse agonists and neutral antagonists of recombinant human A1 adenosine receptors stably expressed in Chinese hamster ovary cellsQ74536219
IB-MECA, an A3 adenosine receptor agonist prevents bone resorption in rats with adjuvant induced arthritisQ80221332
Role of cell-matrix interactions in osteoclast differentiationQ81511726
Adenosine A2A receptor activation and hyaluronan fragment inhibition reduce inflammation in mouse articular chondrocytes stimulated with interleukin-1βQ83886779
P433issue6
P304page(s)290-300
P577publication date2013-03-14
P1433published inTrends in Endocrinology and MetabolismQ15265727
P1476titleAdenosine and bone metabolism
P478volume24

Reverse relations

cites work (P2860)
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Q38929939Effects of tofacitinib on nucleic acid metabolism in human articular chondrocytes
Q37475686Electrical stimulation enhances cell migration and integrative repair in the meniscus
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Q36901374Psoralen and Isopsoralen Ameliorate Sex Hormone Deficiency-Induced Osteoporosis in Female and Male Mice.
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Q35865353Salicylic Acid-Based Polymers for Guided Bone Regeneration Using Bone Morphogenetic Protein-2
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Q47109047The Inactivation of ERK1/2, p38 and NF-kB Is Involved in the Down-Regulation of Osteoclastogenesis and Function by A2B Adenosine Receptor Stimulation
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Q89573871[A novel calcium phosphate cement pre-loaded with chitosan and small molecule adenosine for repairing large cranial defects in rats]

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