Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice

scientific article

Adenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1002/ART.27219
P932PMC publication ID2853194
P698PubMed publication ID20112380
P5875ResearchGate publication ID41175638

P50authorSteven R GoldringQ114399448
Adele L. BoskeyQ42152178
P2093author name stringMone Zaidi
Bruce N Cronstein
Bertil B Fredholm
Stephen B Doty
Firas M Kara
P2860cites workOsteoprotegerin: a novel secreted protein involved in the regulation of bone densityQ24313918
RANK is essential for osteoclast and lymph node developmentQ24598872
Osteoclast differentiation factor is a ligand for osteoprotegerin/osteoclastogenesis-inhibitory factor and is identical to TRANCE/RANKLQ24682139
Bone histomorphometry: standardization of nomenclature, symbols, and units. Report of the ASBMR Histomorphometry Nomenclature CommitteeQ29616160
Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine A1 receptorQ33931315
Marrow stromal stem cellsQ33947769
Calcineurin regulates bone formation by the osteoblastQ34144729
Adenosine A(2A) receptors play a role in the pathogenesis of hepatic cirrhosisQ35546429
Cells of the synovium in rheumatoid arthritis. OsteoclastsQ35769060
Pathological role of osteoclast costimulation in arthritis-induced bone loss.Q36090203
Molecular modeling of adenosine receptors: new results and trends.Q36816987
RANK is the intrinsic hematopoietic cell surface receptor that controls osteoclastogenesis and regulation of bone mass and calcium metabolismQ37108966
Epidemiology of osteoporosis and osteoporotic fracturesQ39832253
Bifurcation of osteoclasts and dendritic cells from common progenitorsQ43757343
Homocysteine levels in patients with rheumatoid arthritis treated with low-dose methotrexateQ44340870
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor geneQ59092154
Coffee, tea and caffeine consumption in relation to osteoporotic fracture risk in a cohort of Swedish womenQ59806015
Anti-arthritic effect of methotrexate: is it really mediated by adenosine?Q73422815
Quantification of Bone Microarchitecture with the Structure Model IndexQ73663325
Could apoptosis be responsible for localized imbalances in bone cell homeostasis?Q78245657
P433issue2
P921main subjectknockout mouseQ1364740
P304page(s)534-541
P577publication date2010-02-01
P1433published inArthritis & RheumatologyQ4797636
P1476titleAdenosine A(1) receptors regulate bone resorption in mice: adenosine A(1) receptor blockade or deletion increases bone density and prevents ovariectomy-induced bone loss in adenosine A(1) receptor-knockout mice
P478volume62

Reverse relations

cites work (P2860)
Q35106323Aberrant bone density in aging mice lacking the adenosine transporter ENT1.
Q37318889Activation of adenosine A(2A) receptor reduces osteoclast formation via PKA- and ERK1/2-mediated suppression of NFκB nuclear translocation
Q35951939Adenosine A(2A) receptor ligation inhibits osteoclast formation.
Q35953968Adenosine A1 receptor regulates osteoclast formation by altering TRAF6/TAK1 signaling.
Q33919462Adenosine A1 receptors (A1Rs) play a critical role in osteoclast formation and function.
Q36067491Adenosine A2A receptor activation prevents wear particle-induced osteolysis
Q41453417Adenosine Receptor Stimulation Improves Glucocorticoid-Induced Osteoporosis in a Rat Model
Q39158939Adenosine Receptors as a Biological Pathway for the Anti-Inflammatory and Beneficial Effects of Low Frequency Low Energy Pulsed Electromagnetic Fields
Q50115228Adenosine abolishes MTX-induced suppression of osteoclastogenesis and inflammatory bone destruction in adjuvant-induced arthritis
Q34036039Adenosine and bone metabolism
Q45609994Adenosine blocks aminopterin-induced suppression of osteoclast differentiation
Q37948081Adenosine receptor targeting in health and disease
Q29346491Adenosine receptors as drug targets--what are the challenges?
Q37118787Adenosine regulates bone metabolism via A1, A2A, and A2B receptors in bone marrow cells from normal humans and patients with multiple myeloma.
Q37850997Advances in osteoclast biology: old findings and new insights from mouse models
Q55062269Age-dependent variations of cancellous bone in response to ovariectomy in C57BL/6J mice.
Q21131280An emerging role for adenosine and its receptors in bone homeostasis
Q64944461Bone Marrow Adipose Tissue and Skeletal Health.
Q35840782Bone destruction by receptor activator of nuclear factor κB ligand-expressing T cells in chronic gouty arthritis
Q35612746CD73-generated adenosine promotes osteoblast differentiation
Q47133411Caffeine at a Moderate Dose Did Not Affect the Skeletal System of Rats with Streptozotocin-Induced Diabetes
Q91598371Dipyridamole Augments Three-Dimensionally Printed Bioactive Ceramic Scaffolds to Regenerate Craniofacial Bone
Q35410561Direct or indirect stimulation of adenosine A2A receptors enhances bone regeneration as well as bone morphogenetic protein-2.
Q42035054Does adenosine play a role in bone formation, resorption and repair?
Q92924705Dysregulation of ectonucleotidase-mediated extracellular adenosine during postmenopausal bone loss
Q38664528Effects of pulsed electromagnetic fields on postmenopausal osteoporosis
Q33705612Endogenous adenosine maintains cartilage homeostasis and exogenous adenosine inhibits osteoarthritis progression.
Q44933307Favorable effect of moderate dose caffeine on the skeletal system in ovariectomized rats.
Q34701303International Union of Basic and Clinical Pharmacology. LXXXI. Nomenclature and classification of adenosine receptors--an update
Q40932223Lack of effect of adenosine on the function of rodent osteoblasts and osteoclasts in vitro.
Q64235092Mechanisms of Osteoblastic Bone Metastasis in Prostate Cancer: Role of Prostatic Acid Phosphatase
Q34761392Pulsed electromagnetic fields increased the anti-inflammatory effect of A₂A and A₃ adenosine receptors in human T/C-28a2 chondrocytes and hFOB 1.19 osteoblasts
Q37468714Purinergic signalling in the musculoskeletal system.
Q37442054Regulation of bone and cartilage by adenosine signaling.
Q36746981Regulation of inflammation by adenosine.
Q36070200Regulation of macrophage function by adenosine
Q37337859Rolofylline, an adenosine A1 receptor antagonist, inhibits osteoclast differentiation as an inverse agonist
Q89619982Signaling of the Purinergic System in the Joint
Q92990019The Adenosine A2B Receptor Drives Osteoclast-Mediated Bone Resorption in Hypoxic Microenvironments
Q47109047The Inactivation of ERK1/2, p38 and NF-kB Is Involved in the Down-Regulation of Osteoclastogenesis and Function by A2B Adenosine Receptor Stimulation
Q56262600The role of 3D printing in treating craniomaxillofacial congenital anomalies
Q90913018The role of GPCRs in bone diseases and dysfunctions
Q26768507The role of purinergic receptors in stem cell differentiation

Search more.