Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial

scientific article

Sofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1016/S0140-6736(13)62121-2
P698PubMed publication ID24209977

P2093author name stringHongmei Mo
Xiao Ding
John G McHutchison
William T Symonds
Phillip S Pang
Fernando E Membreno
Eric Lawitz
Robert H Hyland
Fred F Poordad
P2860cites workBoceprevir for previously treated chronic HCV genotype 1 infectionQ24620576
Telaprevir for retreatment of HCV infectionQ29619799
Telaprevir for previously untreated chronic hepatitis C virus infectionQ29619800
Sofosbuvir for previously untreated chronic hepatitis C infectionQ29620137
Boceprevir for untreated chronic HCV genotype 1 infectionQ29620617
Preliminary study of two antiviral agents for hepatitis C genotype 1.Q34030288
A phase 1, randomized, placebo-controlled, 3-day, dose-ranging study of GS-5885, an NS5A inhibitor, in patients with genotype 1 hepatitis C.Q34030597
Nucleotide polymerase inhibitor sofosbuvir plus ribavirin for hepatitis C.Q34320498
Eligibility and safety of triple therapy for hepatitis C: lessons learned from the first experience in a real world settingQ34577107
Sofosbuvir in combination with peginterferon alfa-2a and ribavirin for non-cirrhotic, treatment-naive patients with genotypes 1, 2, and 3 hepatitis C infection: a randomised, double-blind, phase 2 trialQ34649453
Management of adverse effects of Peg-IFN and ribavirin therapy for hepatitis C.Q37851006
Review of direct-acting antiviral agents for the treatment of chronic hepatitis C.Q38111844
Novel therapies for hepatitis C - one pill fits all?Q38117549
A small percentage of patients with hepatitis C receive triple therapy with boceprevir or telaprevir.Q39432467
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Exploratory study of oral combination antiviral therapy for hepatitis C.Q42987725
A phase 2a trial of 12-week interferon-free therapy with two direct-acting antivirals (ABT-450/r, ABT-072) and ribavirin in IL28B C/C patients with chronic hepatitis C genotype 1.Q42989590
Sofosbuvir with pegylated interferon alfa-2a and ribavirin for treatment-naive patients with hepatitis C genotype-1 infection (ATOMIC): an open-label, randomised, multicentre phase 2 trialQ42990184
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end.Q42992965
Dual therapy with the nonstructural protein 5A inhibitor, daclatasvir, and the nonstructural protein 3 protease inhibitor, asunaprevir, in hepatitis C virus genotype 1b-infected null respondersQ43041150
Triple therapy in treatment-experienced patients with HCV-cirrhosis in a multicentre cohort of the French Early Access Programme (ANRS CO20-CUPIC) - NCT01514890.Q44847210
Treatment of chronic non-A,non-B hepatitis with recombinant human alpha interferon. A preliminary reportQ70313812
P433issue9916
P407language of work or nameEnglishQ1860
P921main subjectvirusQ808
ribavirinQ421862
Hepatitis C virusQ708693
patientQ181600
sofosbuvirQ2502747
hepatitis CQ154869
ledipasvirQ15409409
phase II clinical trialQ42824440
P304page(s)515-523
P577publication date2013-11-05
P1433published inThe LancetQ939416
P1476titleSofosbuvir and ledipasvir fixed-dose combination with and without ribavirin in treatment-naive and previously treated patients with genotype 1 hepatitis C virus infection (LONESTAR): an open-label, randomised, phase 2 trial
P478volume383

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Q38581478Treatment of HCV in Patients who Failed First-Generation PI Therapy: a Review of Current Literature.
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Q54268463Treatment of Hepatitis C during Pregnancy-Weighing the Risks and Benefits in Contrast to HIV.
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