Phosphorylation of a central clock transcription factor is required for thermal but not photic entrainment.

scientific article

Phosphorylation of a central clock transcription factor is required for thermal but not photic entrainment. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1371/JOURNAL.PGEN.1004545
P932PMC publication ID4133166
P698PubMed publication ID25121504
P5875ResearchGate publication ID264799308

P50authorPaul E. HardinQ52595274
Jens T VanselowQ56999206
P2093author name stringEun Young Kim
Isaac Edery
Achim Kramer
Fanny Ng
Hyun-Jeong Jeong
Evrim Yildirim
Euna Lee
Yixiao Liu
Eun Hee Jeong
Guruswamy Mahesh
P2860cites workActivating PER repressor through a DBT-directed phosphorylation switchQ21145851
PER-dependent rhythms in CLK phosphorylation and E-box binding regulate circadian transcriptionQ24548191
The circadian regulatory proteins BMAL1 and cryptochromes are substrates of casein kinase IepsilonQ24553966
ON TEMPERATURE INDEPENDENCE IN THE CLOCK SYSTEM CONTROLLING EMERGENCE TIME IN DROSOPHILAQ24559692
NEMO/NLK phosphorylates PERIOD to initiate a time-delay phosphorylation circuit that sets circadian clock speedQ24594785
Circadian organization of behavior and physiology in DrosophilaQ24633391
DOUBLETIME plays a noncatalytic role to mediate CLOCK phosphorylation and repress CLOCK-dependent transcription within the Drosophila circadian clockQ24647875
Temperature regulates transcription in the zebrafish circadian clockQ24816097
Molecular architecture of the mammalian circadian clockQ27004052
The CK2 kinase stabilizes CLOCK and represses its activity in the Drosophila circadian oscillatorQ27316942
Posttranslational mechanisms regulate the mammalian circadian clockQ27863710
A role for casein kinase 2alpha in the Drosophila circadian clockQ28215935
double-time is a novel Drosophila clock gene that regulates PERIOD protein accumulationQ28277205
The Drosophila clock gene double-time encodes a protein closely related to human casein kinase IepsilonQ28277215
Cooperative interaction between phosphorylation sites on PERIOD maintains circadian period in DrosophilaQ28533842
BMAL1-dependent circadian oscillation of nuclear CLOCK: posttranslational events induced by dimerization of transcriptional activators of the mammalian clock systemQ28584828
Rapid activation of CLOCK by Ca2+-dependent protein kinase C mediates resetting of the mammalian circadian clockQ28590061
Exquisite light sensitivity of Drosophila melanogaster cryptochromeQ30456823
Coupling governs entrainment range of circadian clocksQ30497756
Circadian transcription contributes to core period determination in DrosophilaQ33336761
A serine cluster mediates BMAL1-dependent CLOCK phosphorylation and degradationQ33815603
Post-transcriptional regulation contributes to Drosophila clock gene mRNA cyclingQ33887839
Molecular genetic analysis of circadian timekeeping in DrosophilaQ33938983
Transcriptional feedback of Neurospora circadian clock gene by phosphorylation-dependent inactivation of its transcription factorQ63035161
Light and temperature cooperate to regulate the circadian locomotor rhythm of wild type and period mutants of Drosophila melanogasterQ73442578
dCLOCK is present in limiting amounts and likely mediates daily interactions between the dCLOCK-CYC transcription factor and the PER-TIM complexQ73469642
Alterations of per RNA in noncoding regions affect periodicity of circadian behavioral rhythmsQ77447087
Mapping of phosphorylation sites by a multi-protease approach with specific phosphopeptide enrichment and NanoLC-MS/MS analysisQ81054229
A role for CK2 in the Drosophila circadian oscillatorQ47071691
Temperature synchronization of the Drosophila circadian clockQ47071904
How temperature changes reset a circadian oscillatorQ47725740
A Novel C-Terminal Domain of Drosophila PERIOD Inhibits dCLOCK:CYCLE-Mediated TranscriptionQ47940001
Behavior in light-dark cycles of Drosophila mutants that are arrhythmic, blind, or both.Q52546147
The Drosophila CLOCK protein undergoes daily rhythms in abundance, phosphorylation, and interactions with the PER-TIM complex.Q52566479
Drosophila CLOCK protein is under posttranscriptional control and influences light-induced activity.Q52595230
A temperature-dependent timing mechanism is involved in the circadian system that drives locomotor rhythms in the fruit fly Drosophila melanogaster.Q52598572
Temperature cycles drive Drosophila circadian oscillation in constant light that otherwise induces behavioural arrhythmicity.Q52661089
Second messenger and Ras/MAPK signalling pathways regulate CLOCK/CYCLE-dependent transcription.Q52669482
Interactions between circadian neurons control temperature synchronization of Drosophila behavior.Q52684484
Engineering the Drosophila genome: chromosome rearrangements by designQ33969088
Mitogen-activated protein kinase phosphorylates and negatively regulates basic helix-loop-helix-PAS transcription factor BMAL1.Q34099897
Rhythms of mammalian body temperature can sustain peripheral circadian clocksQ34153711
VRILLE feeds back to control circadian transcription of Clock in the Drosophila circadian oscillatorQ34172689
vrille, Pdp1, and dClock form a second feedback loop in the Drosophila circadian clockQ34176690
A hierarchical phosphorylation cascade that regulates the timing of PERIOD nuclear entry reveals novel roles for proline-directed kinases and GSK-3beta/SGG in circadian clocks.Q34213033
P[acman]: a BAC transgenic platform for targeted insertion of large DNA fragments in D. melanogaster.Q34586256
Balance between DBT/CKIepsilon kinase and protein phosphatase activities regulate phosphorylation and stability of Drosophila CLOCK proteinQ34597319
Post-translational modifications regulate the ticking of the circadian clock.Q34605395
Construction of transgenic Drosophila by using the site-specific integrase from phage phiC31Q34644225
The mouse Clock mutation reduces circadian pacemaker amplitude and enhances efficacy of resetting stimuli and phase-response curve amplitudeQ34657918
Temperature effect on entrainment, phase shifting, and amplitude of circadian clocks and its molecular bases.Q34983156
CKI and CKII mediate the FREQUENCY-dependent phosphorylation of the WHITE COLLAR complex to close the Neurospora circadian negative feedback loopQ35052569
The E3 ubiquitin ligase CTRIP controls CLOCK levels and PERIOD oscillations in Drosophila.Q35082658
A fly's eye view of circadian entrainmentQ35163394
A DOUBLETIME kinase binding domain on the Drosophila PERIOD protein is essential for its hyperphosphorylation, transcriptional repression, and circadian clock functionQ35948140
Photic resetting and entrainment in CLOCK-deficient miceQ36222062
Regulating a circadian clock's period, phase and amplitude by phosphorylation: insights from DrosophilaQ36608877
The phospho-occupancy of an atypical SLIMB-binding site on PERIOD that is phosphorylated by DOUBLETIME controls the pace of the clock.Q36802821
Roles of CLOCK phosphorylation in suppression of E-box-dependent transcriptionQ37233438
Post-translational modifications in circadian rhythmsQ37394741
ON THE SIGNIFICANCE OF TRANSIENTS IN DAILY RHYTHMS.Q37618571
Clocks not winding down: unravelling circadian networksQ37802192
Kinases and phosphatases in the mammalian circadian clockQ37849981
Phosphorylations: Making the Neurosporacrassa circadian clock tickQ37859907
A master CLOCK hard at work brings rhythm to the transcriptomeQ39332067
Role for Slimb in the degradation of Drosophila Period protein phosphorylated by Doubletime.Q40688638
Amplitude Model for the Effects of Mutations and Temperature on Period and Phase Resetting of the Neurospora Circadian OscillatorQ41153556
A complementary transposon tool kit for Drosophila melanogaster using P and piggyBacQ42045441
The double-time protein kinase regulates the subcellular localization of the Drosophila clock protein periodQ42169242
NEMO kinase contributes to core period determination by slowing the pace of the Drosophila circadian oscillatorQ42729851
Protein kinase G type II is required for night-to-day progression of the mammalian circadian clock.Q42826370
The Amplitude of Circadian Oscillations: Temperature Dependence, Latitudinal Clines, and the Photoperiodic Time MeasurementQ43607935
Cryptochrome antagonizes synchronization of Drosophila's circadian clock to temperature cyclesQ45323941
Systematic generation of high-resolution deletion coverage of the Drosophila melanogaster genomeQ46518014
Cryptochrome-positive and -negative clock neurons in Drosophila entrain differentially to light and temperatureQ47070012
The F-box protein slimb controls the levels of clock proteins period and timelessQ47070034
Drosophila clock can generate ectopic circadian clocksQ47070173
A role for the segment polarity gene shaggy/GSK-3 in the Drosophila circadian clockQ47070465
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue8
P921main subjectphosphorylationQ242736
Clock Dmel_CG7391Q29811609
P304page(s)e1004545
P577publication date2014-08-14
P1433published inPLOS GeneticsQ1893441
P1476titlePhosphorylation of a central clock transcription factor is required for thermal but not photic entrainment
P478volume10

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cites work (P2860)
Q41588956A simple method to measure CLOCK-BMAL1 DNA binding activity in tissue and cell extracts
Q92021860AMP-Activated Protein Kinase Regulates Circadian Rhythm by Affecting CLOCK in Drosophila
Q37435108Cycles of circadian illuminance are sufficient to entrain and maintain circadian locomotor rhythms in Drosophila
Q36736190Identification of Light-Sensitive Phosphorylation Sites on PERIOD That Regulate the Pace of Circadian Rhythms in Drosophila
Q37199927Pacemaker-neuron-dependent disturbance of the molecular clockwork by a Drosophila CLOCK mutant homologous to the mouse Clock mutation
Q36362306RETRACTED: Calcium and SOL Protease Mediate Temperature Resetting of Circadian Clocks
Q26775669Recent progress in understanding the role of ecdysteroids in adult insects: Germline development and circadian clock in the fruit fly Drosophila melanogaster
Q35781100The molecular ticks of the Drosophila circadian clock
Q38381813Warming Up Your Tick-Tock: Temperature-Dependent Regulation of Circadian Clocks

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