Sulforaphane controls TPA-induced MMP-9 expression through the NF-κB signaling pathway, but not AP-1, in MCF-7 breast cancer cells

scientific article

Sulforaphane controls TPA-induced MMP-9 expression through the NF-κB signaling pathway, but not AP-1, in MCF-7 breast cancer cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.5483/BMBREP.2013.46.4.160
P932PMC publication ID4133889
P698PubMed publication ID23615261
P5875ResearchGate publication ID236327744

P2093author name stringHyun Jo Youn
Sung Hoo Jung
Sung-Ho Lee
Eun-Mi Noh
Jeong-Mi Kim
Young-Rae Lee
Jong-Suk Kim
Bo-Mi Hwang
Eun Yong Chung
Byeong-Soo Kim
Ji-Hey Han
P2860cites workMatrix metalloproteinases and tumor invasion: from correlation and causality to the clinicQ41084451
Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cellsQ41105683
Changing views of the role of matrix metalloproteinases in metastasisQ41592276
EGF-R regulates MMP function in fibroblasts through MAPK and AP-1 pathways.Q42509418
Modulatory properties of various natural chemopreventive agents on the activation of NF-kappaB signaling pathwayQ44893517
Mechanism of sulforaphane-induced cell cycle arrest and apoptosis in human colon cancer cells.Q44961768
Sulforaphane inhibits TNF-alpha-induced activation of p38 MAP kinase and VCAM-1 and MCP-1 expression in endothelial cellsQ46092389
Sulforaphane inhibition of monocyte adhesion via the suppression of ICAM-1 and NF-kappaB is dependent upon glutathione depletion in endothelial cells.Q46772747
Amplification of IL-1 beta-induced matrix metalloproteinase-9 expression by superoxide in rat glomerular mesangial cells is mediated by increased activities of NF-kappa B and activating protein-1 and involves activation of the mitogen-activated protQ47816419
Results of lung metastasectomy from breast cancer: prognostic criteria on the basis of 467 cases of the International Registry of Lung Metastases.Q53311270
Phorbol ester-induced generation of reactive oxygen species is protein kinase cbeta -dependent and required for SAPK activation.Q54032805
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cellsQ73574350
Alpha-lipoic acid inhibits matrix metalloproteinase-9 expression by inhibiting NF-kappaB transcriptional activityQ79862188
Modulation of cell-mediated immune response in B16F-10 melanoma-induced metastatic tumor-bearing C57BL/6 mice by sulforaphaneQ81236030
A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structureQ24562666
Therapeutic potential of inhibition of the NF-kappaB pathway in the treatment of inflammation and cancerQ24681630
A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingQ25938984
Overexpression of matrix-metalloproteinase-9 in human breast cancer: a potential favourable indicator in node-negative patientsQ28366039
Ascofuranone suppresses PMA-mediated matrix metalloproteinase-9 gene activation through the Ras/Raf/MEK/ERK- and Ap1-dependent mechanismsQ28568067
Protein kinase C: structure, function, and regulationQ28618608
Cancer statistics, 2005Q29617572
AP-1 function and regulationQ29618422
NF-kappa B: a lesson in family valuesQ29620228
Profile of gene expression induced by the tumour promotor TPA in murine epithelial cellsQ31135271
Tumor necrosis factor-alpha augments matrix metalloproteinase-9 production in skeletal muscle cells through the activation of transforming growth factor-beta-activated kinase 1 (TAK1)-dependent signaling pathwayQ34132341
Multi-targeted prevention of cancer by sulforaphaneQ34781826
Matrix metalloproteinases and tumor metastasisQ36471104
Matrix metalloproteinases and their inhibitors in connective tissue remodelingQ37174661
Sulforaphane protects against cytokine- and streptozotocin-induced beta-cell damage by suppressing the NF-kappaB pathwayQ38497459
Novel and therapeutic effect of caffeic acid and caffeic acid phenyl ester on hepatocarcinoma cells: complete regression of hepatoma growth and metastasis by dual mechanismQ38516002
Synergistic inhibitory effect of sulforaphane and 5-fluorouracil in high and low metastasis cell lines of salivary gland adenoid cystic carcinomaQ39930973
Suppression of PMA-induced tumor cell invasion by capillarisin via the inhibition of NF-kappaB-dependent MMP-9 expressionQ40033980
Sulforaphane suppresses lipopolysaccharide-induced cyclooxygenase-2 (COX-2) expression through the modulation of multiple targets in COX-2 gene promoterQ40053378
PMA-induced up-regulation of MMP-9 is regulated by a PKCalpha-NF-kappaB cascade in human lung epithelial cellsQ40164097
D,L-Sulforaphane-induced cell death in human prostate cancer cells is regulated by inhibitor of apoptosis family proteins and Apaf-1.Q40241718
Sulforaphane causes autophagy to inhibit release of cytochrome C and apoptosis in human prostate cancer cellsQ40272756
Curcumin suppresses phorbol ester-induced matrix metalloproteinase-9 expression by inhibiting the PKC to MAPK signaling pathways in human astroglioma cellsQ40384946
Ascochlorin inhibits matrix metalloproteinase-9 expression by suppressing activator protein-1-mediated gene expression through the ERK1/2 signaling pathway: inhibitory effects of ascochlorin on the invasion of renal carcinoma cellsQ40428673
Suppression of NF-kappaB and NF-kappaB-regulated gene expression by sulforaphane and PEITC through IkappaBalpha, IKK pathway in human prostate cancer PC-3 cells.Q40430279
Nuclear factor kappa B is a molecular target for sulforaphane-mediated anti-inflammatory mechanisms.Q40798546
P433issue4
P921main subjectNF-κBQ411114
P304page(s)201-206
P577publication date2013-04-01
P1433published inBMB ReportsQ15764027
P1476titleSulforaphane controls TPA-induced MMP-9 expression through the NF-κB signaling pathway, but not AP-1, in MCF-7 breast cancer cells
P478volume46

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cites work (P2860)
Q38597105Antitumor activity and expression profiles of genes induced by sulforaphane in human melanoma cells.
Q58605123Casticin inhibits breast cancer cell migration and invasion by downregulation of PI3K/Akt signaling pathway
Q64099958Cellular and Molecular Effects of High-Molecular-Weight Heparin on Matrix Metalloproteinase 9 Expression
Q39429454Dietary Natural Products for Prevention and Treatment of Breast Cancer.
Q27026986Dietary Sulforaphane in Cancer Chemoprevention: The Role of Epigenetic Regulation and HDAC Inhibition
Q34179905Down-modulation of Bis reduces the invasive ability of glioma cells induced by TPA, through NF-κB mediated activation of MMP-9
Q50049957Effects of a Standard American Diet and an Anti-inflammatory Diet in Male and Female Mice.
Q35068725Essential oils purified from Schisandrae semen inhibits tumor necrosis factor-α-induced matrix metalloproteinase-9 activation and migration of human aortic smooth muscle cells
Q93156976Investigations on the Role of the Fibrinolytic Pathway on Outflow Facility Regulation
Q38174668Molecular approaches toward targeted cancer prevention with some food plants and their products: inflammatory and other signal pathways
Q39045906Nrf2 targeting by sulforaphane: A potential therapy for cancer treatment
Q36261424Perfluorooctanoic acid enhances colorectal cancer DLD-1 cells invasiveness through activating NF-κB mediated matrix metalloproteinase-2/-9 expression
Q35117980Rapid preparation of high-purity nuclear proteins from a small number of cultured cells for use in electrophoretic mobility shift assays
Q59807366Sulforaphane from Cruciferous Vegetables: Recent Advances to Improve Glioblastoma Treatment
Q35973580Sulforaphane induces apoptosis and inhibits invasion in U251MG glioblastoma cells
Q35109117Sulforaphane inhibits invasion via activating ERK1/2 signaling in human glioblastoma U87MG and U373MG cells
Q33865037Sulforaphane reduces vascular inflammation in mice and prevents TNF-α-induced monocyte adhesion to primary endothelial cells through interfering with the NF-κB pathway.
Q38823095Targeting cancer stem cells and signaling pathways by phytochemicals: Novel approach for breast cancer therapy
Q64897342The involvement of spinal annexin A10/NF-κB/MMP-9 pathway in the development of neuropathic pain in rats.
Q36237715Trastuzumab resistance induces EMT to transform HER2(+) PTEN(-) to a triple negative breast cancer that requires unique treatment options

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