Characterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradation

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Characterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradation is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1091/MBC.E05-03-0246
P932PMC publication ID1237077
P698PubMed publication ID16079177
P5875ResearchGate publication ID7681198

P2093author name stringArmando J Parodi
Olga A Castro
Federico Movsichoff
P2860cites workIdentification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesisQ22010397
Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesisQ22010659
Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesisQ22254696
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycleQ24296412
The specificity of the yeast and human class I ER alpha 1,2-mannosidases involved in ER quality control is not as strict previously reportedQ24300584
Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteinsQ24313639
A novel ER alpha-mannosidase-like protein accelerates ER-associated degradationQ24522524
Crystal structure of a class I α1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality controlQ27621384
Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidasesQ27627138
Rer1p, a retrieval receptor for endoplasmic reticulum membrane proteins, is dynamically localized to the Golgi apparatus by coatomerQ27931848
N-Glycosylation affects endoplasmic reticulum degradation of a mutated derivative of carboxypeptidase yscY in yeastQ27934822
Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteinsQ27937049
Degradation of misfolded endoplasmic reticulum glycoproteins in Saccharomyces cerevisiae is determined by a specific oligosaccharide structureQ27938571
Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeastQ27939809
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexinQ28212764
A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradationQ28296585
BiP/Kar2p serves as a molecular chaperone during carboxypeptidase Y folding in yeastQ28303811
Immunolocalization of UDP-glucose:glycoprotein glucosyltransferase indicates involvement of pre-Golgi intermediates in protein quality controlQ28582340
A misfolded protein conformation is not a sufficient condition for in vivo glucosylation by the UDP-Glc:glycoprotein glucosyltransferaseQ33889672
Protein glucosylation and its role in protein foldingQ34019347
Dissecting glycoprotein quality control in the secretory pathwayQ34394333
Golgi apparatus immunolocalization of endomannosidase suggests post-endoplasmic reticulum glucose trimming: implications for quality controlQ34783037
Quality Control and Protein Folding in the Secretory PathwayQ35564863
A new stress protein: synthesis of Schizosaccharomyces pombe UDP--Glc:glycoprotein glucosyltransferase mRNA is induced by stress conditions but the enzyme is not essential for cell viabilityQ35852846
The UDP-Glc:Glycoprotein glucosyltransferase is essential for Schizosaccharomyces pombe viability under conditions of extreme endoplasmic reticulum stressQ36288216
Endoplasmic reticulum (ER)-associated degradation of misfolded N-linked glycoproteins is suppressed upon inhibition of ER mannosidase I.Q38308427
Mannose trimming targets mutant alpha(2)-plasmin inhibitor for degradation by the proteasomeQ38315499
Genetic evidence for the heterodimeric structure of glucosidase II. The effect of disrupting the subunit-encoding genes on glycoprotein foldingQ38321171
Intracellular disposal of incompletely folded human alpha1-antitrypsin involves release from calnexin and post-translational trimming of asparagine-linked oligosaccharidesQ38347593
Endoplasmic reticulum-associated degradation of mammalian glycoproteins involves sugar chain trimming to Man6-5GlcNAc2.Q38353217
Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.Q38354843
Degradation of a short-lived glycoprotein from the lumen of the endoplasmic reticulum: the role of N-linked glycans and the unfolded protein responseQ38615280
N-glycan structure of a short-lived variant of ribophorin I expressed in the MadIA214 glycosylation-defective cell line reveals the role of a mannosidase that is not ER mannosidase I in the process of glycoprotein degradationQ40793481
Pivotal role of calnexin and mannose trimming in regulating the endoplasmic reticulum-associated degradation of major histocompatibility complex class I heavy chain.Q40881364
Glucosidase and mannosidase inhibitors mediate increased secretion of mutant alpha1 antitrypsin Z.Q40906032
Demonstration that a kifunensine-resistant alpha-mannosidase with a unique processing action on N-linked oligosaccharides occurs in rat liver endoplasmic reticulum and various cultured cellsQ41509550
Characterization of a specific alpha-mannosidase involved in oligosaccharide processing in Saccharomyces cerevisiaeQ42225036
Glycoprotein quality control in the endoplasmic reticulum. Mannose trimming by endoplasmic reticulum mannosidase I times the proteasomal degradation of unassembled immunoglobulin subunitsQ43559578
Activation of the Ras-cAMP signal transduction pathway inhibits the proteasome-independent degradation of misfolded protein aggregates in the endoplasmic reticulum lumenQ43722260
The use of 1-deoxymannojirimycin to evaluate the role of various alpha-mannosidases in oligosaccharide processing in intact cellsQ43812124
Trypanosoma cruzi cells undergo an alteration in protein N-glycosylation upon differentiation.Q45304947
Transitory effects of glucose starvation on the synthesis of dolichol-linked oligosaccharides in mammalian cellsQ53570294
Protein glycosylation in Trypanosoma cruzi. The mechanism of glycosylation and structure of protein-bound oligosaccharidesQ70257294
Glucose starvation alters lipid-linked oligosaccharide biosynthesis in Chinese hamster ovary cellsQ70797561
Glycoprotein synthesis in yeast. Identification of Man8GlcNAc2 as an essential intermediate in oligosaccharide processingQ71463421
Glycoprotein synthesis in yeast. Early events in N-linked oligosaccharide processing in Schizosaccharomyces pombeQ72403431
Purification to homogeneity of UDP-glucose:glycoprotein glucosyltransferase from Schizosaccharomyces pombe and apparent absence of the enzyme fro Saccharomyces cerevisiaeQ72863760
Degradation of endoplasmic reticulum (ER) quality control substrates requires transport between the ER and GolgiQ73794069
Substrate specificities of recombinant murine Golgi alpha1, 2-mannosidases IA and IB and comparison with endoplasmic reticulum and Golgi processing alpha1,2-mannosidasesQ77158781
P433issue10
P407language of work or nameEnglishQ1860
P921main subjectSchizosaccharomyces pombeQ2236682
ubiquitin-dependent glycoprotein ERAD pathwayQ21115846
P304page(s)4714-4724
P577publication date2005-08-03
P1433published inMolecular Biology of the CellQ2338259
P1476titleCharacterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradation
P478volume16

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cites work (P2860)
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Q35624728Characterization of an extracellularly derived α-mannosidase from the liquid exudate of the sclerotia of Sclerotinia sclerotiorum (Lib.) de Bary
Q51767890Demonstration that endoplasmic reticulum-associated degradation of glycoproteins can occur downstream of processing by endomannosidase.
Q28510507EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans
Q28593084EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming
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Q24646392Getting in and out from calnexin/calreticulin cycles
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Q36580003N-linked glycan recognition and processing: the molecular basis of endoplasmic reticulum quality control
Q34123363Proteasome nuclear import mediated by Arc3 can influence efficient DNA damage repair and mitosis in Schizosaccharomyces pombe.
Q43140053Purification and biochemical characterisation of endoplasmic reticulum alpha1,2-mannosidase from Sporothrix schenckiil
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Q35867639The evolution of N-glycan-dependent endoplasmic reticulum quality control factors for glycoprotein folding and degradation