EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans

scientific journal article

EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/GLYCOB/CWQ001
P3181OpenCitations bibliographic resource ID3843291
P698PubMed publication ID20065073

P50authorKazuhiro NagataQ11550232
Ikuo WadaQ37380204
Koichi KatoQ57030726
P2093author name stringNobuko Hosokawa
Yukiko Kamiya
Annette Herscovics
Linda O Tremblay
Barry Sleno
P2860cites workIdentification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesisQ22010397
Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesisQ22010659
Characterization of a cDNA encoding a novel human Golgi alpha 1, 2-mannosidase (IC) involved in N-glycan biosynthesisQ22254696
Role of EDEM in the release of misfolded glycoproteins from the calnexin cycleQ24296412
Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradationQ24300458
Human OS-9, a lectin required for glycoprotein endoplasmic reticulum-associated degradation, recognizes mannose-trimmed N-glycansQ24313146
Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteinsQ24313639
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiPQ24316328
A novel ER alpha-mannosidase-like protein accelerates ER-associated degradationQ24522524
Crystal structure of a class I α1,2-mannosidase involved in N-glycan processing and endoplasmic reticulum quality controlQ27621384
Defining the glycan destruction signal for endoplasmic reticulum-associated degradationQ27932810
Roles of protein-disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in endoplasmic reticulum-associated degradationQ27934273
Mnl1p, an alpha -mannosidase-like protein in yeast Saccharomyces cerevisiae, is required for endoplasmic reticulum-associated degradation of glycoproteinsQ27937049
Degradation of Misfolded Endoplasmic Reticulum Glycoproteins in Saccharomyces cerevisiae Is Determined by a Specific Oligosaccharide StructureQ27938571
Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulumQ27939524
Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeastQ27939809
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexinQ28212764
EDEM accelerates ERAD by preventing aberrant dimer formation of misfolded alpha1-antitrypsinQ28235801
ERAD: the long road to destructionQ28264823
A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradationQ28296585
EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimmingQ28593084
Roles of N-linked glycans in the endoplasmic reticulumQ29616458
Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation.Q30332997
Oligosaccharide modification in the early secretory pathway directs the selection of a misfolded glycoprotein for degradation by the proteasomeQ33852597
Characterization of Schizosaccharomyces pombe ER alpha-mannosidase: a reevaluation of the role of the enzyme on ER-associated degradationQ34049758
Dissecting glycoprotein quality control in the secretory pathwayQ34394333
The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tagsQ36153965
A window of opportunity: timing protein degradation by trimming of sugars and ubiquitinsQ36160302
Protein quality control in the early secretory pathwayQ36446833
Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteinsQ36820743
Ubiquitin receptors and ERAD: a network of pathways to the proteasomeQ36973974
The EDEM and Yos9p families of lectin-like ERAD factorsQ36975199
Cytoplasmic peptide:N-glycanase and catabolic pathway for free N-glycans in the cytosolQ36976680
How sugars convey information on protein conformation in the endoplasmic reticulumQ36998731
The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulumQ37100233
The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I.Q37289488
Enhancement of endoplasmic reticulum (ER) degradation of misfolded Null Hong Kong alpha1-antitrypsin by human ER mannosidase I.Q38354843
Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidasesQ40087924
EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.Q40229528
Comparison between 1-deoxynojirimycin and N-methyl-1-deoxynojirimycin as inhibitors of oligosaccharide processing in intestinal epithelial cellsQ42040360
Calculated two-dimensional sugar map of pyridylaminated oligosaccharides: elucidation of the jack bean alpha-mannosidase digestion pathway of Man9GlcNAc2.Q44000417
Analysis of N-glycans in embryonated chicken egg chorioallantoic and amniotic cells responsible for binding and adaptation of human and avian influenza viruses.Q46318153
P433issue5
P921main subjecttrimming of terminal mannose on C branchQ21431316
ER degradation enhancer, mannosidase alpha-like 1Q21984441
P304page(s)567-575
P577publication date2010-01-11
P1433published inGlycobiologyQ5572596
P1476titleEDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycans
P478volume20

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cites work (P2860)
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