Characterization of early EDEM1 protein maturation events and their functional implications

scientific article

Characterization of early EDEM1 protein maturation events and their functional implications is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M111.243998
P932PMC publication ID3137065
P698PubMed publication ID21632540
P5875ResearchGate publication ID51183845

P2093author name stringDaniel N Hebert
James H Cormier
Taku Tamura
P2860cites workRole of EDEM in the release of misfolded glycoproteins from the calnexin cycleQ24296412
Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradationQ24302539
Human EDEM2, a novel homolog of family 47 glycosidases, is involved in ER-associated degradation of glycoproteinsQ24313639
Human XTP3-B forms an endoplasmic reticulum quality control scaffold with the HRD1-SEL1L ubiquitin ligase complex and BiPQ24316328
A dual role for EDEM1 in the processing of rod opsinQ24320047
Cotranslational and posttranslational N-glycosylation of polypeptides by distinct mammalian OST isoformsQ24321464
EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complexQ24338144
A novel ER alpha-mannosidase-like protein accelerates ER-associated degradationQ24522524
The concept of translocational regulationQ24654677
One step at a time: endoplasmic reticulum-associated degradationQ24658302
EDEM1 reveals a quality control vesicular transport pathway out of the endoplasmic reticulum not involving the COPII exit sitesQ24683239
N-linked glycans direct the cotranslational folding pathway of influenza hemagglutinin.Q27863759
Defining the glycan destruction signal for endoplasmic reticulum-associated degradationQ27932810
Roles of protein-disulfide isomerase-mediated disulfide bond formation of yeast Mnl1p in endoplasmic reticulum-associated degradationQ27934273
Htm1 protein generates the N-glycan signal for glycoprotein degradation in the endoplasmic reticulumQ27939524
Distinct retrieval and retention mechanisms are required for the quality control of endoplasmic reticulum protein foldingQ27939944
In and Out of the ER: Protein Folding, Quality Control, Degradation, and Related Human DiseasesQ28109625
EDEM as an acceptor of terminally misfolded glycoproteins released from calnexinQ28212764
Determination of the distance between the oligosaccharyltransferase active site and the endoplasmic reticulum membraneQ28267028
A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradationQ28296585
EDEM1 accelerates the trimming of alpha1,2-linked mannose on the C branch of N-glycansQ28510507
ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ERQ28512215
EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimmingQ28593084
Locating proteins in the cell using TargetP, SignalP and related toolsQ29547300
Roles of N-linked glycans in the endoplasmic reticulumQ29616458
Stringent requirement for HRD1, SEL1L, and OS-9/XTP3-B for disposal of ERAD-LS substratesQ33615098
Signal sequence insufficiency contributes to neurodegeneration caused by transmembrane prion proteinQ33689595
Oligosaccharide modification in the early secretory pathway directs the selection of a misfolded glycoprotein for degradation by the proteasomeQ33852597
Quality and quantity control at the endoplasmic reticulumQ34090425
The organizing principle in the formation of the T cell receptor-CD3 complex.Q34167740
Transient, lectin-like association of calreticulin with folding intermediates of cellular and viral glycoproteinsQ34451461
The molecular chaperone calnexin facilitates folding and assembly of class I histocompatibility moleculesQ35846706
Posttranscriptional regulation of hepatitis B virus replication by the precore proteinQ35874866
The glycan code of the endoplasmic reticulum: asparagine-linked carbohydrates as protein maturation and quality-control tagsQ36153965
Stage- and ribosome-specific alterations in nascent chain-Sec61p interactions accompany translocation across the ER membraneQ36235677
The number and location of glycans on influenza hemagglutinin determine folding and association with calnexin and calreticulinQ36276590
Intracellular protein topogenesisQ36360251
In vitro translation and assembly of a complete T cell receptor-CD3 complexQ36380431
The surprising complexity of signal sequencesQ36571413
SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteinsQ36858538
Protein-protein interactions in the membrane: sequence, structural, and biological motifsQ37210616
The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I.Q37289488
Glycoprotein folding, quality control and ER-associated degradationQ37555655
ERAD substrates: which way out?Q37660718
Chaperone function of calreticulin when expressed in the endoplasmic reticulum as the membrane-anchored and soluble forms.Q38292055
Basal autophagy is involved in the degradation of the ERAD component EDEM1.Q39876239
Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activitiesQ39985945
EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation.Q40229528
Regulation of protein compartmentalization expands the diversity of protein functionQ40366867
The cotranslational maturation of the type I membrane glycoprotein tyrosinase: the heat shock protein 70 system hands off to the lectin-based chaperone systemQ40409191
Degradation of trafficking-defective long QT syndrome type II mutant channels by the ubiquitin-proteasome pathway.Q40448063
Calnexin and calreticulin promote folding, delay oligomerization and suppress degradation of influenza hemagglutinin in microsomes.Q41065377
Insulin gene mutations as cause of diabetes in children negative for five type 1 diabetes autoantibodiesQ41854466
Translation rate of human tyrosinase determines its N-linked glycosylation levelQ43509483
Carbohydrates act as sorting determinants in ER-associated degradation of tyrosinaseQ44909736
Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replicationQ44986570
Signal sequences initiate the pathway of maturation in the endoplasmic reticulum lumen.Q46274296
A frameshift mutation results in a truncated alpha 1-antitrypsin that is retained within the rough endoplasmic reticulumQ68093404
The alpha chain of the T cell antigen receptor is degraded in the cytosolQ73574925
P4510describes a project that usesImageJQ1659584
P433issue28
P407language of work or nameEnglishQ1860
P304page(s)24906-24915
P577publication date2011-06-01
P1433published inJournal of Biological ChemistryQ867727
P1476titleCharacterization of early EDEM1 protein maturation events and their functional implications
P478volume286

Reverse relations

cites work (P2860)
Q30360183A Golgi-localized mannosidase (MAN1B1) plays a non-enzymatic gatekeeper role in protein biosynthetic quality control.
Q42827982A shared endoplasmic reticulum-associated degradation pathway involving the EDEM1 protein for glycosylated and nonglycosylated proteins
Q48316566Arabidopsis Class I α-Mannosidases MNS4 and MNS5 Are Involved in Endoplasmic Reticulum-Associated Degradation of Misfolded Glycoproteins
Q28078319Arms Race between Enveloped Viruses and the Host ERAD Machinery
Q28078736Co- and Post-Translational Protein Folding in the ER
Q41720457Dual control of pcdh8l/PCNS expression and function in Xenopus laevis neural crest cells by adam13/33 via the transcription factors tfap2α and arid3a
Q57705922EDEM1's mannosidase-like domain binds ERAD client proteins in a redox-sensitive manner and possesses catalytic activity
Q39012161ERADication of EDEM1 occurs by selective autophagy and requires deglycosylation by cytoplasmic peptide N-glycanase.
Q36732745Extreme C-terminal sites are posttranslocationally glycosylated by the STT3B isoform of the OST.
Q36282189Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis
Q38606832Glycosylation-directed quality control of protein folding
Q37583253Lipid disequilibrium disrupts ER proteostasis by impairing ERAD substrate glycan trimming and dislocation
Q92192855Profiling Optimal Conditions for Capturing EDEM Proteins Complexes in Melanoma Using Mass Spectrometry
Q38103530Protein folding in the endoplasmic reticulum
Q24295118TMTC1 and TMTC2 are novel endoplasmic reticulum tetratricopeptide repeat-containing adapter proteins involved in calcium homeostasis
Q38507330The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation.
Q24339440The role of EDEM2 compared with EDEM1 in ricin transport from the endoplasmic reticulum to the cytosol

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