| review article | Q7318358 |
| scholarly article | Q13442814 |
| P50 | author | Yong-Hui Zheng | Q87994158 |
| P2093 | author name string | Dylan A Frabutt | |
| P2860 | cites work | Multilayered mechanism of CD4 downregulation by HIV-1 Vpu involving distinct ER retention and ERAD targeting steps | Q21131559 |
| Flagging and docking: dual roles for N-glycans in protein quality control and cellular proteostasis | Q36282189 | ||
| Endoplasmic reticulum degradation requires lumen to cytosol signaling. Transmembrane control of Hrd1p by Hrd3p. | Q36358009 | ||
| The LMP1 oncogene of EBV activates PERK and the unfolded protein response to drive its own synthesis | Q36445900 | ||
| Endoplasmic reticulum stress sensing in the unfolded protein response | Q36626672 | ||
| Human cytomegalovirus gH stability and trafficking are regulated by ER-associated degradation and transmembrane architecture | Q36741322 | ||
| Mechanisms of CD4 downregulation by the Nef and Vpu proteins of primate immunodeficiency viruses | Q36754608 | ||
| Virus glycosylation: role in virulence and immune interactions | Q36775963 | ||
| Model for intracellular folding of the human immunodeficiency virus type 1 gp120 | Q36780628 | ||
| Penetration of nonenveloped viruses into the cytoplasm | Q36800410 | ||
| Glycoprotein folding and the role of EDEM1, EDEM2 and EDEM3 in degradation of folding-defective glycoproteins | Q36820743 | ||
| A systematic study of the N-glycosylation sites of HIV-1 envelope protein on infectivity and antibody-mediated neutralization | Q36827883 | ||
| SEL1L nucleates a protein complex required for dislocation of misfolded glycoproteins | Q36858538 | ||
| Somatic overgrowth associated with homozygous mutations in both MAN1B1 and SEC23A | Q36859407 | ||
| HIV-1 Nef: at the crossroads | Q36926697 | ||
| ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death. | Q36954378 | ||
| Sterol homeostasis requires regulated degradation of squalene monooxygenase by the ubiquitin ligase Doa10/Teb4 | Q37040167 | ||
| How early studies on secreted and membrane protein quality control gave rise to the ER associated degradation (ERAD) pathway: the early history of ERAD. | Q37045978 | ||
| A novel HIV-1 restriction factor that is biologically distinct from APOBEC3 cytidine deaminases in a human T cell line CEM.NKR. | Q37177043 | ||
| In vitro analysis of Hrd1p-mediated retrotranslocation of its multispanning membrane substrate 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase | Q37200837 | ||
| The mammalian UPR boosts glycoprotein ERAD by suppressing the proteolytic downregulation of ER mannosidase I. | Q37289488 | ||
| Identification, expression, and characterization of a cDNA encoding human endoplasmic reticulum mannosidase I, the enzyme that catalyzes the first mannose trimming step in mammalian Asn-linked oligosaccharide biosynthesis | Q22010397 | ||
| Cloning and expression of a specific human alpha 1,2-mannosidase that trims Man9GlcNAc2 to Man8GlcNAc2 isomer B during N-glycan biosynthesis | Q22010659 | ||
| The unfolded protein response: integrating stress signals through the stress sensor IRE1α | Q24293771 | ||
| Protein synthesis and endoplasmic reticulum stress can be modulated by the hepatitis C virus envelope protein E2 through the eukaryotic initiation factor 2alpha kinase PERK | Q24296386 | ||
| Role of EDEM in the release of misfolded glycoproteins from the calnexin cycle | Q24296412 | ||
| A membrane protein required for dislocation of misfolded proteins from the ER | Q24297703 | ||
| A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol | Q24297732 | ||
| Membrane topology of the yeast endoplasmic reticulum-localized ubiquitin ligase Doa10 and comparison with its human ortholog TEB4 (MARCH-VI) | Q24299616 | ||
| In vitro mannose trimming property of human ER α-1,2 mannosidase I | Q24299633 | ||
| Endoplasmic reticulum (ER) mannosidase I is compartmentalized and required for N-glycan trimming to Man5-6GlcNAc2 in glycoprotein ER-associated degradation | Q24300458 | ||
| The specificity of the yeast and human class I ER alpha 1,2-mannosidases involved in ER quality control is not as strict previously reported | Q24300584 | ||
| EDEM2 initiates mammalian glycoprotein ERAD by catalyzing the first mannose trimming step | Q24301651 | ||
| Selective ubiquitylation of p21 and Cdt1 by UBCH8 and UBE2G ubiquitin-conjugating enzymes via the CRL4Cdt2 ubiquitin ligase complex | Q24305063 | ||
| The TRC8 E3 ligase ubiquitinates MHC class I molecules before dislocation from the ER | Q24311488 | ||
| OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD | Q24312778 | ||
| HRD1 and UBE2J1 target misfolded MHC class I heavy chains for endoplasmic reticulum-associated degradation | Q24337606 | ||
| EDEM1 recognition and delivery of misfolded proteins to the SEL1L-containing ERAD complex | Q24338144 | ||
| A novel ER alpha-mannosidase-like protein accelerates ER-associated degradation | Q24522524 | ||
| Murine polyomavirus requires the endoplasmic reticulum protein Derlin-2 to initiate infection | Q24674111 | ||
| The HIV glycan shield as a target for broadly neutralizing antibodies | Q26786540 | ||
| Identifying the ERAD ubiquitin E3 ligases for viral and cellular targeting of MHC class I | Q26799569 | ||
| How viruses use the endoplasmic reticulum for entry, replication, and assembly | Q26996825 | ||
| Modulation of the unfolded protein response by the human hepatitis B virus | Q26999215 | ||
| The delicate balance between secreted protein folding and endoplasmic reticulum-associated degradation in human physiology | Q27015793 | ||
| The hepatitis C virus glycan shield and evasion of the humoral immune response | Q27023390 | ||
| Structural basis for catalysis and inhibition of N-glycan processing class I alpha 1,2-mannosidases | Q27627138 | ||
| Malectin: A Novel Carbohydrate-binding Protein of the Endoplasmic Reticulum and a Candidate Player in the Early Steps of Protein N-Glycosylation | Q27650749 | ||
| Key steps in ERAD of luminal ER proteins reconstituted with purified components | Q27929992 | ||
| When worlds collide: IP(3) receptors and the ERAD pathway | Q37364711 | ||
| The Polyomaviridae: Contributions of virus structure to our understanding of virus receptors and infectious entry | Q37373700 | ||
| Role of 26S proteasome and HRD genes in the degradation of 3-hydroxy-3-methylglutaryl-CoA reductase, an integral endoplasmic reticulum membrane protein | Q37383994 | ||
| HIV-1 Vpu - an ion channel in search of a job. | Q37384691 | ||
| The ubiquitylation machinery of the endoplasmic reticulum | Q37424805 | ||
| Vertebrate protein glycosylation: diversity, synthesis and function | Q37601831 | ||
| Comprehensive functional analysis of N-linked glycans on Ebola virus GP1. | Q37631492 | ||
| The mitochondrial translocator protein, TSPO, inhibits HIV-1 envelope glycoprotein biosynthesis via the endoplasmic reticulum-associated protein degradation pathway | Q37643757 | ||
| Family 47 alpha-mannosidases in N-glycan processing | Q37661461 | ||
| Human endoplasmic reticulum mannosidase I is subject to regulated proteolysis | Q37672299 | ||
| ERAD and ERAD tuning: disposal of cargo and of ERAD regulators from the mammalian ER. | Q37809383 | ||
| Protein quality control in the ER: balancing the ubiquitin checkbook | Q37953004 | ||
| The cell biology of receptor-mediated virus entry | Q37962258 | ||
| Unfolded protein response in hepatitis C virus infection | Q38218108 | ||
| Virus and cell fusion mechanisms | Q38226984 | ||
| Regulation of Endoplasmic Reticulum-Associated Protein Degradation (ERAD) by Ubiquitin. | Q38237571 | ||
| The expanding roles of endoplasmic reticulum stress in virus replication and pathogenesis | Q38244316 | ||
| Glycan regulation of ER-associated degradation through compartmentalization | Q38280554 | ||
| Interdependence of hemagglutinin glycosylation and neuraminidase as regulators of influenza virus growth: a study by reverse genetics | Q38311181 | ||
| Endoplasmic reticulum-associated degradation of mammalian glycoproteins involves sugar chain trimming to Man6-5GlcNAc2. | Q38353217 | ||
| The African swine fever virus DP71L protein recruits the protein phosphatase 1 catalytic subunit to dephosphorylate eIF2alpha and inhibits CHOP induction but is dispensable for these activities during virus infection | Q38482694 | ||
| The Role of Lectin-Carbohydrate Interactions in the Regulation of ER-Associated Protein Degradation. | Q38507330 | ||
| HIV-1 Vpr increases Env expression by preventing Env from endoplasmic reticulum-associated protein degradation (ERAD). | Q38762277 | ||
| Mannosidase IA is in Quality Control Vesicles and Participates in Glycoprotein Targeting to ERAD. | Q38775886 | ||
| Unfolded proteins are Ire1-activating ligands that directly induce the unfolded protein response | Q38845249 | ||
| Regulation of diacylglycerol acyltransferase 2 protein stability by gp78-associated endoplasmic-reticulum-associated degradation | Q38995770 | ||
| Segregation and rapid turnover of EDEM1 by an autophagy-like mechanism modulates standard ERAD and folding activities | Q39985945 | ||
| Stimulation of ERAD of misfolded null Hong Kong alpha1-antitrypsin by Golgi alpha1,2-mannosidases | Q40087924 | ||
| Two endoplasmic reticulum-associated degradation (ERAD) systems for the novel variant of the mutant dysferlin: ubiquitin/proteasome ERAD(I) and autophagy/lysosome ERAD(II). | Q40164655 | ||
| Cytoplasmic localization of the ORF2 protein of hepatitis E virus is dependent on its ability to undergo retrotranslocation from the endoplasmic reticulum | Q40182274 | ||
| EDEM1 regulates ER-associated degradation by accelerating de-mannosylation of folding-defective polypeptides and by inhibiting their covalent aggregation. | Q40229528 | ||
| The ATF6 branch of unfolded protein response and apoptosis are activated to promote African swine fever virus infection. | Q40281455 | ||
| MHC class I ubiquitination by a viral PHD/LAP finger protein. | Q40773241 | ||
| Human cytomegalovirus glycoproteins | Q41454511 | ||
| Secretion of a truncated form of the human immunodeficiency virus type 1 envelope glycoprotein | Q41570066 | ||
| Human cytomegalovirus penetrates host cells by pH-independent fusion at the cell surface | Q41597223 | ||
| Zernike phase contrast electron microscopy of ice-embedded influenza A virus | Q41623220 | ||
| Simian Virus 40 depends on ER protein folding and quality control factors for entry into host cells | Q41623826 | ||
| Three-dimensional structure of herpes simplex virus from cryo-electron tomography | Q41628861 | ||
| The MRH domain suggests a shared ancestry for the mannose 6-phosphate receptors and other N-glycan-recognising proteins | Q42655325 | ||
| The pathway of HCV IRES-mediated translation initiation | Q42988470 | ||
| Ubiquitin-proteasome system mediates heme oxygenase-1 degradation through endoplasmic reticulum-associated degradation pathway | Q43999017 | ||
| Distinct ubiquitin-ligase complexes define convergent pathways for the degradation of ER proteins | Q27931299 | ||
| Usa1 functions as a scaffold of the HRD-ubiquitin ligase. | Q27932065 | ||
| Autoubiquitination of the Hrd1 Ligase Triggers Protein Retrotranslocation in ERAD. | Q27935283 | ||
| Role of the cysteine residues in the alpha1,2-mannosidase involved in N-glycan biosynthesis in Saccharomyces cerevisiae. The conserved Cys340 and Cys385 residues form an essential disulfide bond | Q27935815 | ||
| The Saccharomyces cerevisiae processing alpha 1,2-mannosidase is localized in the endoplasmic reticulum, independently of known retrieval motifs. | Q27938527 | ||
| Htm1p, a mannosidase-like protein, is involved in glycoprotein degradation in yeast | Q27939809 | ||
| N-Glycan-based ER Molecular Chaperone and Protein Quality Control System: The Calnexin Binding Cycle | Q28085581 | ||
| Association of the SEL1L protein transmembrane domain with HRD1 ubiquitin ligase regulates ERAD-L | Q28119008 | ||
| ERGIC-53 and traffic in the secretory pathway | Q28143617 | ||
| Signal peptide peptidase is required for dislocation from the endoplasmic reticulum | Q28243253 | ||
| Tracking global patterns of N-linked glycosylation site variation in highly variable viral glycoproteins: HIV, SIV, and HCV envelopes and influenza hemagglutinin | Q28264707 | ||
| ERAD: the long road to destruction | Q28264823 | ||
| A novel human WD protein, h-beta TrCp, that interacts with HIV-1 Vpu connects CD4 to the ER degradation pathway through an F-box motif | Q28276184 | ||
| The ubiquitin-domain protein HERP forms a complex with components of the endoplasmic reticulum associated degradation pathway | Q28282028 | ||
| Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation | Q28284392 | ||
| A novel stress-induced EDEM variant regulating endoplasmic reticulum-associated glycoprotein degradation | Q28296585 | ||
| TSPO interacts with VDAC1 and triggers a ROS-mediated inhibition of mitochondrial quality control | Q28508394 | ||
| Plasma membrane profiling defines an expanded class of cell surface proteins selectively targeted for degradation by HCMV US2 in cooperation with UL141 | Q28546343 | ||
| EDEM3, a soluble EDEM homolog, enhances glycoprotein endoplasmic reticulum-associated degradation and mannose trimming | Q28593084 | ||
| Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response | Q29547299 | ||
| The unfolded protein response: from stress pathway to homeostatic regulation | Q29547396 | ||
| Roles of N-linked glycans in the endoplasmic reticulum | Q29616458 | ||
| Distribution and three-dimensional structure of AIDS virus envelope spikes | Q29617562 | ||
| TMEM129 is a Derlin-1 associated ERAD E3 ligase essential for virus-induced degradation of MHC-I. | Q29871423 | ||
| Elucidation of the molecular logic by which misfolded alpha 1-antitrypsin is preferentially selected for degradation. | Q30332997 | ||
| A Golgi-localized mannosidase (MAN1B1) plays a non-enzymatic gatekeeper role in protein biosynthetic quality control. | Q30360183 | ||
| Playing hide and seek: how glycosylation of the influenza virus hemagglutinin can modulate the immune response to infection. | Q30360290 | ||
| Paramyxovirus ultrastructure and genome packaging: cryo-electron tomography of sendai virus | Q30489060 | ||
| Electron tomography analysis of envelope glycoprotein trimers on HIV and simian immunodeficiency virus virions | Q30499561 | ||
| Structure of the native Sec61 protein-conducting channel | Q30667297 | ||
| The SARS Coronavirus 3a protein causes endoplasmic reticulum stress and induces ligand-independent downregulation of the type 1 interferon receptor | Q33519556 | ||
| Ube2j2 ubiquitinates hydroxylated amino acids on ER-associated degradation substrates | Q33590955 | ||
| Biosynthesis, cleavage, and degradation of the human immunodeficiency virus 1 envelope glycoprotein gp160. | Q33685950 | ||
| Herpes simplex virus 1 infection activates the endoplasmic reticulum resident kinase PERK and mediates eIF-2alpha dephosphorylation by the gamma(1)34.5 protein | Q33717136 | ||
| Coronavirus infection, ER stress, apoptosis and innate immunity | Q33767779 | ||
| Coronaviruses Hijack the LC3-I-positive EDEMosomes, ER-derived vesicles exporting short-lived ERAD regulators, for replication | Q44986570 | ||
| No evidence of the unfolded protein response in patients with chronic hepatitis C virus infection | Q45369635 | ||
| Recruitment of HIV and its receptors to dendritic cell-T cell junctions | Q47563778 | ||
| Selective inhibition of endoplasmic reticulum-associated degradation rescues DeltaF508-cystic fibrosis transmembrane regulator and suppresses interleukin-8 levels: therapeutic implications. | Q53627014 | ||
| The yeast ERAD-C ubiquitin ligase Doa10 recognizes an intramembrane degron. | Q55378035 | ||
| Short Communication: Activating Transcription Factor 4 (ATF4) Promotes HIV Type 1 Activation | Q58620069 | ||
| Cleavage by signal peptide peptidase is required for the degradation of selected tail-anchored proteins | Q33797023 | ||
| PB1-F2 attenuates virulence of highly pathogenic avian H5N1 influenza virus in chickens. | Q33800303 | ||
| Both E protein glycans adversely affect dengue virus infectivity but are beneficial for virion release | Q33826834 | ||
| A novel herpes simplex virus glycoprotein, gL, forms a complex with glycoprotein H (gH) and affects normal folding and surface expression of gH | Q33931805 | ||
| Retrovirus envelope protein complex structure in situ studied by cryo-electron tomography | Q33935062 | ||
| Retroviral Rem protein requires processing by signal peptidase and retrotranslocation for nuclear function | Q33981988 | ||
| ER stress, autophagy, and RNA viruses | Q34003896 | ||
| Why HIV virions have low numbers of envelope spikes: implications for vaccine development | Q34016070 | ||
| Activation of ERAD pathway by human hepatitis B virus modulates viral and subviral particle production | Q34213852 | ||
| How viruses hijack the ERAD tuning machinery. | Q34262042 | ||
| The mitochondrion in apoptosis: how Pandora's box opens | Q34286386 | ||
| Signal integration via PKR. | Q34467907 | ||
| Importance of hemagglutinin glycosylation for the biological functions of influenza virus | Q34556366 | ||
| Glycosylation affects cleavage of an H5N2 influenza virus hemagglutinin and regulates virulence | Q34584070 | ||
| Dengue virus modulates the unfolded protein response in a time-dependent manner | Q34800188 | ||
| The HCMV gene products US2 and US11 target MHC class I molecules for degradation in the cytosol | Q34840250 | ||
| Cytomegalovirus downregulates IRE1 to repress the unfolded protein response | Q34945470 | ||
| Mammalian ER mannosidase I resides in quality control vesicles, where it encounters its glycoprotein substrates | Q34960623 | ||
| Mutations in the alpha 1,2-mannosidase gene, MAN1B1, cause autosomal-recessive intellectual disability. | Q35103799 | ||
| Characterization of early EDEM1 protein maturation events and their functional implications | Q35107478 | ||
| Golgi localization of ERManI defines spatial separation of the mammalian glycoprotein quality control system | Q35160707 | ||
| Derlin-1 is a rhomboid pseudoprotease required for the dislocation of mutant α-1 antitrypsin from the endoplasmic reticulum | Q35381401 | ||
| Role of the endoplasmic reticulum-associated degradation (ERAD) pathway in degradation of hepatitis C virus envelope proteins and production of virus particles | Q35423569 | ||
| Proteasome 19S RP binding to the Sec61 channel plays a key role in ERAD. | Q35556723 | ||
| HIV infection and antiretroviral therapy lead to unfolded protein response activation | Q35684397 | ||
| Virus entry: molecular mechanisms and biomedical applications | Q35712985 | ||
| Role of CD4 receptor down-regulation during HIV-1 infection | Q35724962 | ||
| Influenza A viral replication is blocked by inhibition of the inositol-requiring enzyme 1 (IRE1) stress pathway. | Q35762999 | ||
| Derlin-1 and UBXD8 are engaged in dislocation and degradation of lipidated ApoB-100 at lipid droplets | Q35790894 | ||
| Human Cytomegalovirus gH/gL/gO Promotes the Fusion Step of Entry into All Cell Types, whereas gH/gL/UL128-131 Broadens Virus Tropism through a Distinct Mechanism | Q35913890 | ||
| ERManI (Endoplasmic Reticulum Class I α-Mannosidase) Is Required for HIV-1 Envelope Glycoprotein Degradation via Endoplasmic Reticulum-associated Protein Degradation Pathway | Q36065264 | ||
| Endoplasmic reticulum-associated degradation | Q36280341 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 9 | |
| P407 | language of work or name | English | Q1860 |
| P577 | publication date | 2016-09-19 | |
| P1433 | published in | Viruses | Q7935305 |
| P1476 | title | Arms Race between Enveloped Viruses and the Host ERAD Machinery | |
| P478 | volume | 8 |
| Q45326108 | Innate sensing of influenza A virus hemagglutinin glycoproteins by the host endoplasmic reticulum (ER) stress pathway triggers a potent antiviral response via ER-associated protein degradation. |
| Q59357968 | Organelle dynamics and viral infections: at cross roads |
| Q55233756 | Oxidative and endoplasmic reticulum stress in respiratory disease. |
| Q98902950 | Vesicular Stomatitis Virus Encoding a Destabilized Tumor Antigen Improves Activation of Anti-tumor T Cell Responses |
| Q90100014 | Zika virus noncoding sfRNAs sequester multiple host-derived RNA-binding proteins and modulate mRNA decay and splicing during infection |
Search more.