Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters.

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Poly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters. is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1002/J.1460-2075.1993.TB05909.X
P932PMC publication ID413492
P698PubMed publication ID8508777

P2093author name stringJ Eggermont
N J Proudfoot
P2860cites workMAZ, a zinc finger protein, binds to c-MYC and C2 gene sequences regulating transcriptional initiation and terminationQ24316955
Transcription termination and the regulation of gene expressionQ28299849
Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5'-flanking elementsQ28302180
The yeast actin intron contains a cryptic promoter that can be switched on by preventing transcriptional interferenceQ28776312
Characterization of three optional promoters in the 5' region of the human aldolase A geneQ34179217
Promoter occlusion: Transcription through a promoter may inhibit its activityQ34250774
Transcriptional interference in avian retroviruses—implications for the promoter insertion model of leukaemogenesisQ34257238
A poly(A) addition site and a downstream termination region are required for efficient cessation of transcription by RNA polymerase II in the mouse beta maj-globin geneQ34369553
Genes, genes and more genes in the human major histocompatibility complexQ35284071
myc function and regulationQ35671084
Sequences in the human c-myc P2 promoter affect the elongation and premature termination of transcripts initiated from the upstream P1 promoterQ36703451
Efficiency of utilization of the simian virus 40 late polyadenylation site: effects of upstream sequencesQ36761958
RNA polymerase II transcription termination is mediated specifically by protein binding to a CCAAT box sequenceQ36796710
Identification of a sequence element on the 3' side of AAUAAA which is necessary for simian virus 40 late mRNA 3'-end processing.Q36894844
News from the nucleolus: rRNA gene expressionQ37200698
RNA polymerase: regulation of transcript elongation and terminationQ37374849
Alternative transcription and splicing of the human porphobilinogen deaminase gene result either in tissue-specific or in housekeeping expression.Q37479183
A sequence downstream of A-A-U-A-A-A is required for formation of simian virus 40 late mRNA 3' termini in frog oocytesQ37691120
Transcription elongation and eukaryotic gene regulationQ37935764
Alternative promoters in developmental gene expressionQ38186018
A protein-binding site in the c-myc promoter functions as a terminator of RNA polymerase II transcriptionQ38326933
Interaction of enhancer-binding protein EBP1 (NF-kappa B) with the human immunodeficiency virus type 1 enhancer.Q38341650
Interactions of cellular proteins involved in the transcriptional regulation of the human immunodeficiency virusQ38348287
How RNA polymerase II terminates transcription in higher eukaryotesQ38637923
The primary transcription unit of the human alpha 2 globin gene defined by quantitative RT/PCRQ40420283
Synthesis of a gene for the HIV transactivator protein TAT by a novel single stranded approach involving in vivo gap repairQ40546117
Interaction in vivo between strong closely spaced constitutive promotersQ41022421
A pause site for RNA polymerase II is associated with termination of transcriptionQ41081406
Transcriptional termination between the closely linked human complement genes C2 and factor B: common termination factor for C2 and c-myc?Q41083821
A rabbit beta-globin polyadenylation signal directs efficient termination of transcription of polyomavirus DNA.Q41107135
An apparent pause site in the transcription unit of the rabbit α-globin geneQ41156264
Alpha-thalassaemia caused by a poly(A) site mutation reveals that transcriptional termination is linked to 3' end processing in the human alpha 2 globin geneQ41841618
Transcriptional interference and termination between duplicated alpha-globin gene constructs suggests a novel mechanism for gene regulationQ43993308
Promoter occlusion during ribosomal RNA transcriptionQ45118631
Promoter occlusion prevents transcription of adenovirus polypeptide IX mRNA until after DNA replicationQ45167232
An RNA polymerase I termination site can stimulate the adjacent ribosomal gene promoter by two distinct mechanisms in Xenopus laevisQ45433712
Role of transcriptional interference in the Drosophila melanogaster Adh promoter switch.Q52247655
The promoter-proximal rDNA terminator augments initiation by preventing disruption of the stable transcription complex caused by polymerase read-in.Q52487212
A CCAAT box sequence in the adenovirus major late promoter functions as part of an RNA polymerase II termination signalQ64379160
Multiple SP1 binding sites confer enhancer-independent, replication-activated transcription of HIV-1 and globin gene promotersQ68192530
Regulation of HIV-1 gene expressionQ68512606
Position-dependent sequence elements downstream of AAUAAA are required for efficient rabbit beta-globin mRNA 3' end formationQ68985721
Definition of an efficient synthetic poly(A) siteQ69373727
A functional mRNA polyadenylation signal is required for transcription termination by RNA polymerase IIQ69827439
P433issue6
P407language of work or nameEnglishQ1860
P304page(s)2539-2548
P577publication date1993-06-01
P1433published inThe EMBO JournalQ1278554
P1476titlePoly(A) signals and transcriptional pause sites combine to prevent interference between RNA polymerase II promoters
P478volume12

Reverse relations

cites work (P2860)
Q397177023' Processing and termination of mouse histone transcripts synthesized in vitro by RNA polymerase II.
Q419839383' end formation of pre-mRNA and phosphorylation of Ser2 on the RNA polymerase II CTD are reciprocally coupled in human cells
Q36421452A mouse gene that coordinates epigenetic controls and transcriptional interference to achieve tissue-specific expression
Q27935483A mutation in GRS1, a glycyl-tRNA synthetase, affects 3'-end formation in Saccharomyces cerevisiae
Q35896223A novel transcriptional element in circular DNA monomers of the duck hepatitis B virus
Q34283461An RNA polymerase pause site is associated with the immunoglobulin mus poly(A) site
Q34542364An adeno-associated virus-based intracellular sensor of pathological nuclear factor-κB activation for disease-inducible gene transfer
Q24550997Antisense promoter of human L1 retrotransposon drives transcription of adjacent cellular genes
Q39724192Auxiliary downstream elements are required for efficient polyadenylation of mammalian pre-mRNAs
Q40941230Bioassay for growth hormone releasing hormone (GHRH) using a recombinant receptor and cAMP-responsive reporter system
Q35577266Chemically regulated expression systems and their applications in transgenic plants
Q50763775Cre-mediated site-specific recombination in zebrafish embryos.
Q45876469Creation of a new transgene cloning site near the right ITR of Ad5 results in reduced enhancer interference with tissue-specific and regulatable promoters
Q78482192Definition of transcriptional promoters in the human beta globin locus control region
Q30303893EM visualization of transcription by RNA polymerase II: downstream termination requires a poly(A) signal but not transcript cleavage.
Q36059198Escherichia coli rho factor induces release of yeast RNA polymerase II but not polymerase I or III.
Q40162909Evidence for gene expression by unintegrated human immunodeficiency virus type 1 DNA species
Q91972812Examining multiple cellular pathways at once using multiplex hextuple luciferase assaying
Q28609911Formation of mRNA 3' ends in eukaryotes: mechanism, regulation, and interrelationships with other steps in mRNA synthesis
Q37395618Functional promoter testing using a modified lentiviral transfer vector
Q27937728Genetic identification of factors that modulate ribosomal DNA transcription in Saccharomyces cerevisiae.
Q90212257Genome-Wide CRISPR Screen Reveals Autophagy Disruption as the Convergence Mechanism That Regulates the NRF2 Transcription Factor
Q37294436Highly conductive carbon nanotube matrix accelerates developmental chloride extrusion in central nervous system neurons by increased expression of chloride transporter KCC2
Q33977026Indirect imaging of cardiac-specific transgene expression using a bidirectional two-step transcriptional amplification strategy.
Q36880023Inducible scAAV2.GRE.MMP1 lowers IOP long-term in a large animal model for steroid-induced glaucoma gene therapy
Q40442993Intergenic transcription and transinduction of the human beta-globin locus
Q39528124Intergenic transcription in the human beta-globin gene cluster
Q38301674MAZ-dependent termination between closely spaced human complement genes
Q40040325Multigene families in African swine fever virus: family 505.
Q42645595Nascent transcription from the nmt1 and nmt2 genes of Schizosaccharomyces pombe overlaps neighbouring genes.
Q43226911Orientation-dependent regulation of integrated HIV-1 expression by host gene transcriptional readthrough.
Q40269711Overcoming promoter competition in packaging cells improves production of self-inactivating retroviral vectors
Q41288691Plant mRNA 3'-end formation
Q42651921Poly(A) signals control both transcriptional termination and initiation between the tandem GAL10 and GAL7 genes of Saccharomyces cerevisiae
Q40815645Polypyrimidine tract binding protein modulates efficiency of polyadenylation.
Q37473797Prospects for antisense peptide nucleic acid (PNA) therapies for HIV
Q96352155Rapid and Efficient Synthetic Assembly of Multiplex Luciferase Reporter Plasmids for the Simultaneous Monitoring of Up to Six Cellular Signaling Pathways
Q47100925Site-specific chromosomal gene insertion: Flp recombinase versus Cas9 nuclease
Q43206587Stem-loop 1 of the U1 snRNP plays a critical role in the suppression of HIV-1 polyadenylation.
Q42104053Strong polyadenylation and weak pausing combine to cause efficient termination of transcription in the human Ggamma-globin gene.
Q36549906Termination-altering mutations in the second-largest subunit of yeast RNA polymerase III.
Q73565535Tetracycline-dependent activation of an upstream promoter reveals transcriptional interference between tandem genes within T-DNA in tomato
Q42122438The HIV-1 5' LTR poly(A) site is inactivated by U1 snRNP interaction with the downstream major splice donor site.
Q34757665The Xenopus 9 bp ribosomal terminator (T3 box) is a pause signal for the RNA polymerase I elongation complex
Q28345575The formamidase gene of Aspergillus nidulans: regulation by nitrogen metabolite repression and transcriptional interference by an overlapping upstream gene
Q39605433The retroviruses human immunodeficiency virus type 1 and Moloney murine leukemia virus adopt radically different strategies to regulate promoter-proximal polyadenylation.
Q33783723The vaccinia virus A18R DNA helicase is a postreplicative negative transcription elongation factor.
Q33637632Therapeutic strategies involving the multidrug resistance phenotype: the MDR1 gene as target, chemoprotectant, and selectable marker in gene therapy.
Q39720399Transcription and polyadenylation in a short human intergenic region.
Q42674261Transcription of the human U2 snRNA genes continues beyond the 3' box in vivo
Q34361332Transcription termination downstream of the Saccharomyces cerevisiae FBP1 [changed from FPB1] poly(A) site does not depend on efficient 3'end processing.
Q34440230Transcriptional interference by independently regulated genes occurs in any relative arrangement of the genes and is influenced by chromosomal integration position
Q39723092Transcriptional interference perturbs the binding of Sp1 to the HIV-1 promoter.
Q38310504Transcriptional termination and coupled polyadenylation in vitro
Q42199534Transcriptional termination signals for RNA polymerase II in fission yeast

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