The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse

scientific article

The Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1093/NAR/23.17.3365
P932PMC publication ID307212
P698PubMed publication ID7567444
P5875ResearchGate publication ID15632562

P50authorAlan AshworthQ4706084
Peter KoopmanQ42722625
Paul DennyQ57340639
P2093author name stringE Wright
F Connor
P2860cites workSRY, like HMG1, recognizes sharp angles in DNAQ24294378
A gene from the human sex-determining region encodes a protein with homology to a conserved DNA-binding motifQ24301723
A conserved family of genes related to the testis determining gene, SRYQ24321364
Identification and cloning of TCF-1, a T lymphocyte-specific transcription factor containing a sequence-specific HMG boxQ24561560
DNA binding and bending properties of the post-meiotically expressed Sry-related protein Sox-5Q24562937
Sox-4, an Sry-like HMG box protein, is a transcriptional activator in lymphocytesQ24564380
Seven new members of the Sox gene family expressed during mouse developmentQ24595762
X-ray structure of the GCN4 leucine zipper, a two-stranded, parallel coiled coilQ27655682
A general method applicable to the search for similarities in the amino acid sequence of two proteinsQ27860563
Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferaseQ27860571
Campomelic dysplasia and autosomal sex reversal caused by mutations in an SRY-related geneQ28242642
Autosomal sex reversal and campomelic dysplasia are caused by mutations in and around the SRY-related gene SOX9Q28243215
Hoxa-2 mutant mice exhibit homeotic transformation of skeletal elements derived from cranial neural crestQ28506270
An SRY-related gene expressed during spermatogenesis in the mouse encodes a sequence-specific DNA-binding proteinQ28769978
Transcription factors: structural families and principles of DNA recognitionQ29615317
Transcriptional activation: a complex puzzle with few easy piecesQ29616518
How eukaryotic transcriptional activators workQ29618289
The proline-rich transcriptional activator of CTF/NF-I is distinct from the replication and DNA binding domainQ29618454
A gene mapping to the sex-determining region of the mouse Y chromosome is a member of a novel family of embryonically expressed genesQ29618455
Detection of messenger RNA by in situ hybridization to tissue sections and whole mountsQ29618776
Analysis of Sp1 in vivo reveals multiple transcriptional domains, including a novel glutamine-rich activation motifQ29620290
Differential expression of the mouse homeobox-containing gene Hox-1.4 during male germ cell differentiation and embryonic developmentQ34339524
Segmental expression of Hox-2 homoeobox-containing genes in the developing mouse hindbrain.Q34464666
A distinct Hox code for the branchial region of the vertebrate headQ34545764
The HMG-1 box protein family: classification and functional relationships.Q34749348
Definition of a consensus DNA binding site for SRY.Q34823519
Ancestry and diversity of the HMG box superfamilyQ34984036
Sex-reversing mutations affect the architecture of SRY-DNA complexesQ37640387
DNA Binding Activity of Recombinant SRY from Normal Males and XY FemalesQ38330959
DNA-binding properties of the product of the testis-determining gene and a related proteinQ38332159
Solution structure of a DNA-binding domain from HMG1.Q40519803
The HMG domain of lymphoid enhancer factor 1 bends DNA and facilitates assembly of functional nucleoprotein structuresQ42459873
Use of bacteriophage T7 lysozyme to improve an inducible T7 expression systemQ42476169
Murine developmental control genesQ43789032
Male development of chromosomally female mice transgenic for Sry.Q44051365
The hLEF/TCF-1 alpha HMG protein contains a context-dependent transcriptional activation domain that induces the TCR alpha enhancer in T cellsQ46121592
Retinoic acid alters hindbrain Hox code and induces transformation of rhombomeres 2/3 into a 4/5 identityQ48394035
The Sry-related gene Sox9 is expressed during chondrogenesis in mouse embryosQ52211686
Rapid sequence evolution of the mammalian sex-determining gene SRY.Q52223470
Drosophila Krüppel protein is a transcriptional repressorQ52449047
The murine and Drosophila homeobox gene complexes have common features of organization and expressionQ52453645
Evolution of sex determination and the Y chromosome: SRY-related sequences in marsupialsQ59060893
The zebrafish Zf-Sox 19 protein: a novel member of the Sox family which reveals highly conserved motifs outside of the DNA-binding domainQ72590376
P433issue17
P407language of work or nameEnglishQ1860
P921main subjectnervous systemQ9404
P304page(s)3365-3372
P577publication date1995-09-01
P1433published inNucleic Acids ResearchQ135122
P1476titleThe Sry-related HMG box-containing gene Sox6 is expressed in the adult testis and developing nervous system of the mouse
P478volume23

Reverse relations

cites work (P2860)
Q34008404A direct role of SRY and SOX proteins in pre-mRNA splicing
Q24634000A highly conserved SOX6 double binding site mediates SOX6 gene downregulation in erythroid cells
Q24533335A new long form of Sox5 (L-Sox5), Sox6 and Sox9 are coexpressed in chondrogenesis and cooperatively activate the type II collagen gene
Q28504585A novel N-terminal domain directs membrane localization of mouse testis-specific calpastatin
Q37702418Advances in the understanding of haemoglobin switching
Q33786699An Integrative Developmental Genomics and Systems Biology Approach to Identify an In Vivo Sox Trio-Mediated Gene Regulatory Network in Murine Embryos
Q22253229Cloning and characterisation of the Sry-related transcription factor gene Sox8.
Q28585887Cloning and characterization of mouse mSox13 cDN
Q24290932Cloning, characterization and chromosome mapping of the human SOX6 gene
Q37237329Combinations of closely situated cis-acting elements determine tissue-specific patterns and anterior extent of early Hoxc8 expression
Q89878373Comparative Transcriptomics Analysis of Testicular miRNA from Cryptorchid and Normal Horses
Q24607540Concerted regulation of myofiber-specific gene expression and muscle performance by the transcriptional repressor Sox6
Q24676478Control of cell fate and differentiation by Sry-related high-mobility-group box (Sox) transcription factors
Q48044617CvSox-4, the lizard homologue of the human SOX4 gene, shows remarkable conservation among the amniotes
Q24656897Deletion of long-range regulatory elements upstream of SOX9 causes campomelic dysplasia
Q34277820Diagnostic role of microRNA expression profile in the serum of pregnant women with fetuses with neural tube defects
Q42628095Differential expression of oxidored nitro domain containing protein 1 (NOR1), in mouse tissues and in normal and cancerous human tissues
Q52193937Dynamic expression of chicken Sox2 and Sox3 genes in ectoderm induced to form neural tissue
Q39731947Endogenous tagging of the murine transcription factor Sox5 with hemaglutinin for functional studies
Q38288184Expression and characterization of Xenopus laevis SRY-related cDNAs, xSox17alpha1, xSox17alpha2, xSox18alpha and xSox18beta
Q55467658Expression of SoxE and SoxD genes in human gliomas.
Q48044148Expression of theSox11 gene in mouse embryos suggests roles in neuronal maturation and epithelio-mesenchymal induction
Q48137242Expression profiles of Sox transcription factors within the postnatal rodent testes
Q38867291Expressions of Sox9, Sox5, and Sox13 transcription factors in mice testis during postnatal development.
Q51212688Generation of mice harboring a Sox6 conditional null allele
Q42452928Global developmental delay, progressive relapsing-remitting parkinsonism, and spinal syrinx in a child with SOX6 mutation
Q24546094High expression of the HMG box factor sox-13 in arterial walls during embryonic development
Q35191320High levels of SOX5 decrease proliferative capacity of human B cells, but permit plasmablast differentiation.
Q28211981Identification and characterization of the human long form of Sox5 (L-SOX5) gene
Q31033978Identification of a human glioma antigen, SOX6, recognized by patients' sera
Q47574195Identification of suh gene and evidence for involvement of notch signaling pathway on gonadal differentiation of Yellow River carp (Cyprinus carpio).
Q28592465Identification of two Sox17 messenger RNA isoforms, with and without the high mobility group box region, and their differential expression in mouse spermatogenesis
Q36885704Isolation and Characterization ofXenopus laevis xSox-B1cDNA
Q28505432Isolation and characterization of a mouse SRY-related cDNA, mSox7
Q24324121Isolation and expression of a human SRY-related cDNA, hSOX20
Q22008829Ma1, a novel neuron- and testis-specific protein, is recognized by the serum of patients with paraneoplastic neurological disorders
Q39444324Mechanism of regulatory target selection by the SOX high-mobility-group domain proteins as revealed by comparison of SOX1/2/3 and SOX9.
Q64236979Metformin Promotes Neuronal Differentiation via Crosstalk between Cdk5 and Sox6 in Neuroblastoma Cells
Q53496284MicroRNA-499-5p regulates porcine myofiber specification by controlling Sox6 expression
Q37192445Microarray profiling of microRNAs expressed in testis tissues of developing primates.
Q38356293Molecular cloning and expression of Sox17 in gonads during sex reversal in the rice field eel, a teleost fish with a characteristic of natural sex transformation.
Q28590001Mouse mu opioid receptor distal promoter transcriptional regulation by SOX proteins
Q48681182Neuronal expression, cytosolic localization, and developmental regulation of the organic solute carrier partner 1 in the mouse brain
Q33269548Preferential expression and frequent IgG responses of a tumor antigen, SOX5, in glioma patients
Q34506834Profiling spermatogenic failure in adult testes bearing Sox9-deficient Sertoli cells identifies genes involved in feminization, inflammation and stress.
Q24791043Regulation of Id2 expression by CCAAT/enhancer binding protein beta
Q34416813Regulation of IkappaBbeta expression in testis
Q41697429Regulation of Sexual Dimorphism in Mammals
Q35129037Regulation of Sox6 by cyclin dependent kinase 5 in brain
Q36566150Repression of gonadotropin-releasing hormone promoter activity by the POU homeodomain transcription factor SCIP/Oct-6/Tst-1: a regulatory mechanism of phenotype expression?
Q36763116Role of retinoic acid in the differentiation of embryonal carcinoma and embryonic stem cells
Q36437950SOX genes: architects of development.
Q48246179SOX6 Downregulation Induces γ-Globin in Human β-Thalassemia Major Erythroid Cells
Q24555388SOX6 binds CtBP2 to repress transcription from the Fgf-3 promoter
Q33990276SOX6 controls dorsal progenitor identity and interneuron diversity during neocortical development
Q36567842SOX9 is a potent activator of the chondrocyte-specific enhancer of the pro alpha1(II) collagen gene
Q37343070Sex Change in Clownfish: Molecular Insights from Transcriptome Analysis.
Q38321731Slow and fast fiber isoform gene expression is systematically altered in skeletal muscle of the Sox6 mutant, p100H.
Q41536268Sox genes find their feet
Q25257856Sox6 directly silences epsilon globin expression in definitive erythropoiesis
Q24682020Sox6 is a candidate gene for p100H myopathy, heart block, and sudden neonatal death
Q43767931Sox6 is required for normal fiber type differentiation of fetal skeletal muscle in mice
Q34301577Sox6 overexpression causes cellular aggregation and the neuronal differentiation of P19 embryonic carcinoma cells in the absence of retinoic acid
Q24672174Sox6 regulation of cardiac myocyte development
Q38817971Sox6 suppression induces RA-dependent apoptosis mediated by BMP-4 expression during neuronal differentiation in P19 cells
Q37865447Sox6, jack of all trades: A versatile regulatory protein in vertebrate development
Q43754799Spatially precise DNA bending is an essential activity of the sox2 transcription factor
Q48361828Steroidogenic genes expressions are repressed by high levels of leptin and the JAK/STAT signaling pathway in MA-10 Leydig cells.
Q40495848Suppression of Sox6 in P19 cells leads to failure of neuronal differentiation by retinoic acid and induces retinoic acid-dependent apoptosis
Q40964947Testis expression of hormone-sensitive lipase is conferred by a specific promoter that contains four regions binding testicular nuclear proteins
Q31561274Testis hormone-sensitive lipase expression in spermatids is governed by a short promoter in transgenic mice.
Q40711026Testis-specific HMG-domain protein alters the responses of cells to cisplatin
Q22009352The Sox-13 gene: structure, promoter characterization, and chromosomal localization
Q37568568The SoxD transcription factors--Sox5, Sox6, and Sox13--are key cell fate modulators
Q48029017The mouse Sox5 gene encodes a protein containing the leucine zipper and the Q box
Q34668069The pathway for perception and transduction of low-temperature signals in Synechocystis.
Q51804515The transcription factors Sox5 and Sox9 regulate Catsper1 gene expression.
Q48010592Three High Mobility Group-like Sequences within a 48-Base Pair Enhancer of the Col2a1 Gene Are Required for Cartilage-specific Expression in Vivo
Q36884990Trip12, a HECT domain E3 ubiquitin ligase, targets Sox6 for proteasomal degradation and affects fiber type-specific gene expression in muscle cells
Q33769212Uncoupling of expression of an intronic microRNA and its myosin host gene by exon skipping
Q42621325Unravelling pathways downstream Sox6 induction in K562 erythroid cells by proteomic analysis
Q32077539cDNA cloning of a novel rainbow trout SRY-type HMG box protein, rtSox23, and its functional analysis
Q48640449cSox21 exhibits a complex and dynamic pattern of transcription during embryonic development of the chick central nervous system

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