scholarly article | Q13442814 |
P819 | ADS bibcode | 2010PNAS..10713028S |
P356 | DOI | 10.1073/PNAS.1000546107 |
P932 | PMC publication ID | 2919936 |
P698 | PubMed publication ID | 20615964 |
P5875 | ResearchGate publication ID | 45113506 |
P50 | author | Ulf Müller-Ladner | Q47261506 |
P2093 | author name string | Edgar G Engleman | |
Emily Stein | |||
William H Robinson | |||
Ingo H Tarner | |||
Paula Colmenero | |||
Kalle Söderström | |||
Cristina Teixeira de Matos | |||
Ulrich Purath | |||
P2860 | cites work | Osteoprotegerin ligand is a cytokine that regulates osteoclast differentiation and activation | Q24311588 |
Osteoprotegerin: a novel secreted protein involved in the regulation of bone density | Q24313918 | ||
IFN-gamma-producing human T cells directly induce osteoclastogenesis from human monocytes via the expression of RANKL | Q24338171 | ||
CD56bright NK cells are enriched at inflammatory sites and can engage with monocytes in a reciprocal program of activation | Q80967934 | ||
Induced recruitment of NK cells to lymph nodes provides IFN-gamma for T(H)1 priming | Q80975562 | ||
Natural killer cell degeneration exacerbates experimental arthritis in mice via enhanced interleukin-17 production | Q81899298 | ||
Peripheral blood T lymphocytes from patients with early rheumatoid arthritis express RANKL and interleukin-15 on the cell surface and promote osteoclastogenesis in autologous monocytes | Q83022902 | ||
The ratio of circulating osteoprotegerin to RANKL in early rheumatoid arthritis predicts later joint destruction | Q83880460 | ||
RANK is essential for osteoclast and lymph node development | Q24598872 | ||
osteoprotegerin-deficient mice develop early onset osteoporosis and arterial calcification | Q24603266 | ||
Early rheumatoid arthritis is characterized by a distinct and transient synovial fluid cytokine profile of T cell and stromal cell origin | Q24817058 | ||
Bone resorption by osteoclasts | Q28145169 | ||
Unique subpopulations of CD56+ NK and NK-T peripheral blood lymphocytes identified by chemokine receptor expression repertoire | Q28189785 | ||
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis | Q28589430 | ||
NK cell recognition | Q29615107 | ||
Identification, activation, and selective in vivo ablation of mouse NK cells via NKp46 | Q33278681 | ||
Origin of osteoclasts: mature monocytes and macrophages are capable of differentiating into osteoclasts under a suitable microenvironment prepared by bone marrow-derived stromal cells | Q33803260 | ||
Effects of denosumab on bone mineral density and bone turnover in postmenopausal women | Q34656025 | ||
Mechanisms of TNF-alpha- and RANKL-mediated osteoclastogenesis and bone resorption in psoriatic arthritis | Q34967810 | ||
Osteoprotegerin reduces osteoclast numbers and prevents bone erosion in collagen-induced arthritis | Q35789185 | ||
Natural killer cells trigger differentiation of monocytes into dendritic cells | Q36007747 | ||
Rheumatic diseases: the effects of inflammation on bone | Q36324975 | ||
Interleukin (IL) 15 is a novel cytokine that activates human natural killer cells via components of the IL-2 receptor | Q36363861 | ||
Interleukin 15 is produced by endothelial cells and increases the transendothelial migration of T cells In vitro and in the SCID mouse-human rheumatoid arthritis model In vivo | Q37379361 | ||
Soluble IL-15 receptor alpha-chain administration prevents murine collagen-induced arthritis: a role for IL-15 in development of antigen-induced immunopathology | Q41038908 | ||
Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction | Q41927546 | ||
Congenital osteoclast deficiency in osteopetrotic (op/op) mice is cured by injections of macrophage colony-stimulating factor | Q42139985 | ||
IL-15 is chemotactic for natural killer cells and stimulates their adhesion to vascular endothelium | Q42800241 | ||
NK cells and NKT cells collaborate in host protection from methylcholanthrene-induced fibrosarcoma. | Q43562662 | ||
Human natural killer cells: a unique innate immunoregulatory role for the CD56(bright) subset | Q43600819 | ||
A randomized, double-blind study comparing twenty-four-week treatment with recombinant interferon-gamma versus placebo in the treatment of rheumatoid arthritis | Q49174472 | ||
Activated T lymphocytes suppress osteoclastogenesis by diverting early monocyte/macrophage progenitor lineage commitment towards dendritic cell differentiation through down-regulation of receptor activator of nuclear factor-kappaB and c-Fos. | Q50925640 | ||
Gene and protein characteristics reflect functional diversity of CD56dim and CD56bright NK cells. | Q51583908 | ||
The role of interleukin–15 in T–cell migration and activation in rheumatoid arthritis | Q57232112 | ||
Denosumab treatment effects on structural damage, bone mineral density, and bone turnover in rheumatoid arthritis: A twelve-month, multicenter, randomized, double-blind, placebo-controlled, phase II clinical trial | Q57752107 | ||
T-cell-mediated regulation of osteoclastogenesis by signalling cross-talk between RANKL and IFN-γ | Q59064307 | ||
The murine mutation osteopetrosis is in the coding region of the macrophage colony stimulating factor gene | Q59092154 | ||
In vitro spontaneous osteoclastogenesis of human peripheral blood mononuclear cells is not crucially dependent on T lymphocytes. | Q64892036 | ||
Peripheral blood and synovial fluid monocyte activation in inflammatory arthritis. II. Low levels of synovial fluid and synovial tissue interferon suggest that gamma-interferon is not the primary macrophage activating factor | Q70358362 | ||
The role of NK cells during in vivo antigen-specific antibody responses | Q70994039 | ||
Granzyme-positive cytotoxic cells are specifically increased in early rheumatoid synovial tissue | Q72871576 | ||
Activated human T cells directly induce osteoclastogenesis from human monocytes: possible role of T cells in bone destruction in rheumatoid arthritis patients | Q73880310 | ||
A novel role of IL-15 in the development of osteoclasts: inability to replace its activity with IL-2 | Q74595874 | ||
Differential cytokine and chemokine gene expression by human NK cells following activation with IL-18 or IL-15 in combination with IL-12: implications for the innate immune response | Q77320555 | ||
Amelioration of bone loss in collagen-induced arthritis by neutralizing anti-RANKL monoclonal antibody | Q79826358 | ||
Activating and inhibitory receptors on synovial fluid natural killer cells of arthritis patients: role of CD94/NKG2A in control of cytokine secretion | Q80374068 | ||
Immature dendritic cell transdifferentiation into osteoclasts: a novel pathway sustained by the rheumatoid arthritis microenvironment | Q80445625 | ||
P433 | issue | 29 | |
P407 | language of work or name | English | Q1860 |
P304 | page(s) | 13028-13033 | |
P577 | publication date | 2010-07-06 | |
P1433 | published in | Proceedings of the National Academy of Sciences of the United States of America | Q1146531 |
P1476 | title | Natural killer cells trigger osteoclastogenesis and bone destruction in arthritis | |
P478 | volume | 107 |
Q47231337 | ---Inhibition of histone H3K27 demethylase selectively modulates inflammatory phenotypes of natural killer cells. |
Q54407225 | Absence of Fms-like tyrosine kinase 3 ligand (Flt3L) signalling protects against collagen-induced arthritis. |
Q36005508 | Activation of resorption in fatigue-loaded bone involves both apoptosis and active pro-osteoclastogenic signaling by distinct osteocyte populations |
Q37205119 | Advances in rheumatoid arthritis animal models |
Q33851365 | An alternate STAT6-independent pathway promotes eosinophil influx into blood during allergic airway inflammation |
Q50026700 | Antibiotics with Interleukin-15 inhibition reduces joint inflammation and bone erosions but not cartilage destruction in Staphylococcus aureus-induced arthritis |
Q38872112 | Arthritis models: usefulness and interpretation |
Q39011291 | Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts. |
Q44814337 | Bi(o)communications among peripheral blood fractions: a focus on NK and NKT cell biology in rheumatoid arthritis |
Q24701763 | Bindarit, an inhibitor of monocyte chemotactic protein synthesis, protects against bone loss induced by chikungunya virus infection |
Q36299558 | Bisphosphonate-induced differential modulation of immune cell function in gingiva and bone marrow in vivo: role in osteoclast-mediated NK cell activation |
Q38185586 | Bone and the innate immune system |
Q48328114 | CXCR3/CXCL10 Axis Regulates Neutrophil-NK Cell Cross-Talk Determining the Severity of Experimental Osteoarthritis. |
Q38126407 | Cells of the immune system orchestrate changes in bone cell function |
Q38551006 | Circulating monocytes: an appropriate model for bone-related study |
Q37506724 | Coupling the activities of bone formation and resorption: a multitude of signals within the basic multicellular unit |
Q38079582 | Differential chemotactic receptor requirements for NK cell subset trafficking into bone marrow. |
Q39933017 | Enhanced mesenchymal stromal cell recruitment via natural killer cells by incorporation of inflammatory signals in biomaterials |
Q48368263 | Granzyme A Contributes to Inflammatory Arthritis in Mice Through Stimulation of Osteoclastogenesis. |
Q61801026 | High percentages and activity of synovial fluid NK cells present in patients with advanced stage active Rheumatoid Arthritis |
Q38781384 | Human CD56bright NK Cells: An Update |
Q38700649 | IL15RA is required for osteoblast function and bone mineralization |
Q38134126 | Immune cells and bone: coupling goes both ways. |
Q94229509 | Induction of Krüppel-like factor 2 reduces K/BxN serum-induced arthritis |
Q50051077 | Inflammation, mesenchymal stem cells and bone regeneration |
Q58419491 | Interactions Between Multipotential Stromal Cells (MSCs) and Immune Cells During Bone Healing |
Q59356917 | Interferon-Gamma-Mediated Osteoimmunology |
Q41482320 | Interleukin-15-activated natural killer cells kill autologous osteoclasts via LFA-1, DNAM-1 and TRAIL, and inhibit osteoclast-mediated bone erosion in vitro. |
Q37624160 | Interleukin-22 Secreted by NKp44+ Natural Killer Cells Promotes Proliferation of Fibroblast-Like Synoviocytes in Rheumatoid Arthritis |
Q54614405 | Local gene transfer of OPG prevents joint damage and disease progression in collagen-induced arthritis. |
Q38248430 | Mechanisms of tissue damage in arthritis |
Q28078360 | Mesenchymal Stem Cells Regulate the Innate and Adaptive Immune Responses Dampening Arthritis Progression |
Q50661820 | Molecular signatures and transcriptional regulatory networks of human immature decidual NK and mature peripheral NK cells. |
Q36805029 | NAP-2 Secreted by Human NK Cells Can Stimulate Mesenchymal Stem/Stromal Cell Recruitment |
Q89876422 | NK cell-derived GM-CSF potentiates inflammatory arthritis and is negatively regulated by CIS |
Q34257031 | NK cells are not required for spontaneous autoimmune diabetes in NOD mice |
Q35591444 | NK cells: immune cross-talk and therapeutic implications |
Q37690952 | Natural killer cells in human autoimmune disorders |
Q59878936 | Natural killer cells protect mice from DSS-induced colitis by regulating neutrophil function via the NKG2A receptor |
Q92280803 | Noncoding RNAs Involved in the Pathogenesis of Ankylosing Spondylitis |
Q36750759 | Organ-specific features of natural killer cells |
Q96305136 | Osteoimmunomodulatory effects of biomaterial modification strategies on macrophage polarization and bone regeneration |
Q36335245 | Osteoporotic bone of miR-150-deficient mice: Possibly due to low serum OPG-mediated osteoclast activation |
Q91555207 | Phenotypic and functional characterization of natural killer cells in rheumatoid arthritis-regulation with interleukin-15 |
Q35617594 | Positive regulators of osteoclastogenesis and bone resorption in rheumatoid arthritis |
Q93105617 | Progranulin prevents regulatory NK cell cytotoxicity against antiviral T cells |
Q46897841 | Role of cytolytic impairment of natural killer and natural killer T-cell populations in rheumatoid arthritis |
Q35287485 | SPA0355, a thiourea analogue, inhibits inflammatory responses and joint destruction in fibroblast-like synoviocytes and mice with collagen-induced arthritis |
Q37052226 | The Interplay between the bone and the immune system |
Q52366183 | The Role of the Immune Cells in Fracture Healing. |
Q64120685 | The Uncovered Role of Immune Cells and NK Cells in the Regulation of Bone Metastasis |
Q36317934 | The phenotype of circulating follicular-helper T cells in patients with rheumatoid arthritis defines CD200 as a potential therapeutic target |
Q37809132 | The role of Natural Killer cells in the pathogenesis of rheumatoid arthritis: Major contributors or essential homeostatic modulators? |
Q64102242 | Updates on Osteoimmunology: What's New on the Cross-Talk Between Bone and Immune System |
Q89777999 | Urokinase plasminogen activator and receptor promote collagen-induced arthritis through expression in hematopoietic cells |
Search more.