| scholarly article | Q13442814 |
| P819 | ADS bibcode | 2011PLoSO...625614F |
| P356 | DOI | 10.1371/JOURNAL.PONE.0025614 |
| P932 | PMC publication ID | 3198730 |
| P698 | PubMed publication ID | 22031817 |
| P5875 | ResearchGate publication ID | 51749568 |
| P50 | author | Philippe Chanson | Q58441504 |
| Jacques Young | Q79281866 | ||
| Bruno Francou | Q93163553 | ||
| Anne Guiochon-Mantel | Q114329935 | ||
| Jérôme Bouligand | Q117263983 | ||
| Séverine Trabado | Q57002857 | ||
| Sylvie Brailly-Tabard | Q43098727 | ||
| P2093 | author name string | Pierre Lecomte | |
| Larbi Amazit | |||
| Adela Voican | |||
| Geri Meduri | |||
| Jérôme Fagart | |||
| P2860 | cites work | Central injection of senktide, an NK3 receptor agonist, or neuropeptide Y inhibits LH secretion and induces different patterns of Fos expression in the rat hypothalamus | Q62073287 |
| Predictors of outcome of long-term GnRH therapy in men with idiopathic hypogonadotropic hypogonadism. | Q44126978 | ||
| Kisspeptin neurons in the arcuate nucleus of the ewe express both dynorphin A and neurokinin B. | Q44932139 | ||
| Isolated familial hypogonadotropic hypogonadism and a GNRH1 mutation. | Q45964826 | ||
| Regulation of spermatogenesis in McCune-Albright syndrome: lessons from a 15-year follow-up | Q46573367 | ||
| Kallmann's syndrome: a comparison of the reproductive phenotypes in men carrying KAL1 and FGFR1/KAL2 mutations | Q46832341 | ||
| Hypothalamic dysfunction in a female with isolated hypogonadotropic hypogonadism and compound heterozygous TACR3 mutations and clinical manifestation in her heterozygous mother | Q48235286 | ||
| The effects of neurokinin B upon gonadotrophin release in male rodents. | Q48361192 | ||
| Coexpression of dynorphin and neurokinin B immunoreactivity in the rat hypothalamus: Morphologic evidence of interrelated function within the arcuate nucleus | Q48443918 | ||
| The neurokinin B pathway in human reproduction | Q48727907 | ||
| Incongruent pattern of neurokinin B expression in rat and mouse brains | Q48768313 | ||
| Disruption of the neurokinin-3 receptor (NK3) in mice leads to cognitive deficits. | Q50086799 | ||
| Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome | Q50336618 | ||
| Association study of the polymorphisms in the KISS1 gene with central precocious puberty in Chinese girls. | Q50962485 | ||
| Kallmann syndrome: mutations in the genes encoding prokineticin-2 and prokineticin receptor-2 | Q21092497 | ||
| Discovery of potent kisspeptin antagonists delineate physiological mechanisms of gonadotropin regulation | Q24629064 | ||
| Hypogonadotropic hypogonadism due to loss of function of the KiSS1-derived peptide receptor GPR54 | Q24685744 | ||
| Improved methods for building protein models in electron density maps and the location of errors in these models | Q26776980 | ||
| Neurokinin B stimulates GnRH release in the male monkey (Macaca mulatta) and is colocalized with kisspeptin in the arcuate nucleus | Q28749270 | ||
| Trafficking and quality control of the gonadotropin releasing hormone receptor in health and disease | Q28755163 | ||
| Regulation of SRC-3 intercompartmental dynamics by estrogen receptor and phosphorylation | Q30480773 | ||
| Frequency-dependent regulation of follicle-stimulating hormone beta by pulsatile gonadotropin-releasing hormone is mediated by functional antagonism of bZIP transcription factors | Q33627253 | ||
| Neurokinin 3 receptor immunoreactivity in the septal region, preoptic area and hypothalamus of the female sheep: colocalisation in neurokinin B cells of the arcuate nucleus but not in gonadotrophin-releasing hormone neurones. | Q33652453 | ||
| The biology of gonadotroph regulation | Q33821250 | ||
| TAC3/TACR3 mutations reveal preferential activation of gonadotropin-releasing hormone release by neurokinin B in neonatal life followed by reversal in adulthood | Q33984838 | ||
| Neurokinin B and the hypothalamic regulation of reproduction | Q34354034 | ||
| A family with hypogonadotropic hypogonadism and mutations in the gonadotropin-releasing hormone receptor | Q34446712 | ||
| TAC3 and TACR3 mutations in familial hypogonadotropic hypogonadism reveal a key role for Neurokinin B in the central control of reproduction | Q34902985 | ||
| Hypogonadotropic hypogonadism due to a novel missense mutation in the first extracellular loop of the neurokinin B receptor. | Q35014404 | ||
| Interactions between kisspeptin and neurokinin B in the control of GnRH secretion in the female rat. | Q37174107 | ||
| Regulation of gonadotropin-releasing hormone secretion by kisspeptin/dynorphin/neurokinin B neurons in the arcuate nucleus of the mouse | Q37475488 | ||
| Non-syndromic congenital hypogonadotropic hypogonadism: clinical presentation and genotype-phenotype relationships | Q37704009 | ||
| Involvement of tryptophan W276 and of two surrounding amino acid residues in the high constitutive activity of the ghrelin receptor GHS-R1a | Q39685019 | ||
| The third intracellular loop and carboxyl tail of neurokinin 1 and 3 receptors determine interactions with beta-arrestins | Q40637413 | ||
| Utility of free alpha-subunit as an alternative neuroendocrine marker of gonadotropin-releasing hormone (GnRH) stimulation of the gonadotroph in the human: evidence from normal and GnRH-deficient men. | Q41136889 | ||
| Alpha-subunit secretion in men with idiopathic hypogonadotropic hypogonadism | Q41251665 | ||
| Free luteinizing-hormone beta-subunit in normal subjects and patients with pituitary adenomas | Q42438068 | ||
| Neurokinin B and dynorphin A in kisspeptin neurons of the arcuate nucleus participate in generation of periodic oscillation of neural activity driving pulsatile gonadotropin-releasing hormone secretion in the goat. | Q42467752 | ||
| TAC3 and TACR3 defects cause hypothalamic congenital hypogonadotropic hypogonadism in humans | Q43145611 | ||
| ??? | Q28204045 | ||
| P275 | copyright license | Creative Commons Attribution 4.0 International | Q20007257 |
| P6216 | copyright status | copyrighted | Q50423863 |
| P433 | issue | 10 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | congenital disorder | Q727096 |
| hypogonadism | Q938107 | ||
| hypogonadotropic hypogonadism | Q30990102 | ||
| P304 | page(s) | e25614 | |
| P577 | publication date | 2011-10-21 | |
| P1433 | published in | PLOS One | Q564954 |
| P1476 | title | Normosmic congenital hypogonadotropic hypogonadism due to TAC3/TACR3 mutations: characterization of neuroendocrine phenotypes and novel mutations | |
| P478 | volume | 6 |
| Q90724638 | A TAC3 Missense Variant in a Domestic Shorthair Cat with Testicular Hypoplasia and Persistent Primary Dentition |
| Q50243908 | A neurokinin 3 receptor-selective agonist accelerates pulsatile luteinizing hormone secretion in lactating cattle |
| Q58616873 | A novel stopgain mutation c.G992A (p.W331X) in TACR3 gene was identified in nonobstructive azoospermia by targeted next-generation sequencing |
| Q36463825 | A potential mechanism for the sexual dimorphism in the onset of puberty and incidence of idiopathic central precocious puberty in children: sex-specific kisspeptin as an integrator of puberty signals. |
| Q36385294 | Computational Analysis of Missense Variants of G Protein-Coupled Receptors Involved in the Neuroendocrine Regulation of Reproduction |
| Q28484094 | Congenital hypogonadotropic hypogonadism due to GnRH receptor mutations in three brothers reveal sites affecting conformation and coupling |
| Q35035684 | Congenital hypogonadotropic hypogonadism during childhood: presentation and genetic analyses in 46 boys |
| Q89341662 | Contrôle de l’axe gonadotrope : nouveaux aspects physiologiques et thérapeutiques: Control of the gonadotrope axis: new physiologic and therapeutic aspects |
| Q36282285 | Distribution of gene mutations associated with familial normosmic idiopathic hypogonadotropic hypogonadism |
| Q39321494 | Do Substance P and Neurokinin A Play Important Roles in the Control of LH Secretion in Ewes? |
| Q37634265 | Effects of neurokinin B administration on reproductive hormone secretion in healthy men and women |
| Q59042604 | Effects of the Hormone Kisspeptin on Reproductive Hormone Release in Humans |
| Q35979485 | Familial normosmic idiopathic hypogonadotropic hypogonadism: is there a phenotypic marker for each genetic mutation? Report of three cases and review of literature |
| Q34427039 | GPR54-dependent stimulation of luteinizing hormone secretion by neurokinin B in prepubertal rats |
| Q90569848 | Genetics of congenital hypogonadotropic hypogonadism: peculiarities and phenotype of an oligogenic disease |
| Q36439417 | Increased neurokinin B (Tac2) expression in the mouse arcuate nucleus is an early marker of pubertal onset with differential sensitivity to sex steroid-negative feedback than Kiss1. |
| Q28288195 | Interactions between kisspeptins and neurokinin B |
| Q47612221 | Intracellular Trafficking of Gonadotropin Receptors in Health and Disease |
| Q37017449 | Mutational analysis of TAC3 and TACR3 genes in patients with idiopathic central pubertal disorders |
| Q34342881 | Mutations in FGF17, IL17RD, DUSP6, SPRY4, and FLRT3 are identified in individuals with congenital hypogonadotropic hypogonadism |
| Q37351126 | Mutations in G protein-coupled receptors that impact receptor trafficking and reproductive function. |
| Q92136241 | Neurokinin 3 Receptor Antagonists Do Not Increase FSH or Estradiol Secretion in Menopausal Women |
| Q30359856 | Neurokinin B is critical for normal timing of sexual maturation but dispensable for adult reproductive function in female mice |
| Q51138209 | Neurokinin B receptor antagonism decreases luteinising hormone pulse frequency and amplitude and delays puberty onset in the female rat. |
| Q30382924 | Optimization of Novel Antagonists to the Neurokinin-3 Receptor for the Treatment of Sex-Hormone Disorders (Part II). |
| Q36273551 | Point mutations in KAL1 and the mitochondrial gene MT-tRNA(cys) synergize to produce Kallmann syndrome phenotype. |
| Q39838836 | Prevalence of KISS1 Receptor mutations in a series of 603 patients with normosmic congenital hypogonadotrophic hypogonadism and characterization of novel mutations: a single-centre study. |
| Q34920649 | R31C GNRH1 mutation and congenital hypogonadotropic hypogonadism |
| Q21131272 | Reproduction, smell, and neurodevelopmental disorders: genetic defects in different hypogonadotropic hypogonadal syndromes |
| Q37657090 | TACR3 mutations disrupt NK3R function through distinct mechanisms in GnRH-deficient patients. |
| Q35872725 | Tacking toward reconciliation on Tacr3/TACR3 mutations |
| Q28485191 | Two families with normosmic congenital hypogonadotropic hypogonadism and biallelic mutations in KISS1R (KISS1 receptor): clinical evaluation and molecular characterization of a novel mutation |
| Q30422142 | Uncovering novel reproductive defects in neurokinin B receptor null mice: closing the gap between mice and men. |
| Q49437047 | Update on the Genetics of Idiopathic Hypogonadotropic Hypogonadism |
| Q37256645 | Use of genetic models of idiopathic hypogonadotrophic hypogonadism in mice and men to understand the mechanisms of disease |
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