| scholarly article | Q13442814 |
| P2093 | author name string | Wang R | |
| Ball MJ | |||
| Clarke S | |||
| Cotter RJ | |||
| Heinrikson RL | |||
| Roher AE | |||
| Reardon IM | |||
| Zürcher-Neely HA | |||
| Lowenson JD | |||
| Wolkow C | |||
| P433 | issue | 5 | |
| P407 | language of work or name | English | Q1860 |
| P921 | main subject | Alzheimer's disease | Q11081 |
| Beta amyloid | Q417667 | ||
| P304 | page(s) | 3072-3083 | |
| P577 | publication date | 1993-02-01 | |
| P1433 | published in | Journal of Biological Chemistry | Q867727 |
| P1476 | title | Structural alterations in the peptide backbone of beta-amyloid core protein may account for its deposition and stability in Alzheimer's disease | |
| P478 | volume | 268 |
| Q48778991 | 1α,25-Dihydroxyvitamin D3 reduces cerebral amyloid-β accumulation and improves cognition in mouse models of Alzheimer's disease |
| Q46575307 | A Computational Study of the Mechanism of Succinimide Formation in the Asn-His Sequence: Intramolecular Catalysis by the His Side Chain. |
| Q34381799 | A distinct subfraction of Aβ is responsible for the high-affinity Pittsburgh compound B-binding site in Alzheimer's disease brain |
| Q36407976 | A rapid, comprehensive liquid chromatography-mass spectrometry (LC-MS)-based survey of the Asp isomers in crystallins from human cataract lenses |
| Q44902352 | A seed for Alzheimer amyloid in the brain. |
| Q28387681 | A structural model for Alzheimer's beta -amyloid fibrils based on experimental constraints from solid state NMR |
| Q46320596 | APP/Aβ structural diversity and Alzheimer's disease pathogenesis |
| Q41856113 | Acetic acid can catalyze succinimide formation from aspartic acid residues by a concerted bond reorganization mechanism: a computational study |
| Q35285651 | Advanced glycation end products contribute to amyloidosis in Alzheimer disease |
| Q31840691 | Age-dependent changes in brain, CSF, and plasma amyloid (beta) protein in the Tg2576 transgenic mouse model of Alzheimer's disease. |
| Q38743102 | Alternative Selection of β-Site APP-Cleaving Enzyme 1 (BACE1) Cleavage Sites in Amyloid β-Protein Precursor (APP) Harboring Protective and Pathogenic Mutations within the Aβ Sequence |
| Q37124928 | Alternative pathways for production of beta-amyloid peptides of Alzheimer's disease |
| Q33786789 | Alzheimer's Aβ peptides with disease-associated N-terminal modifications: influence of isomerisation, truncation and mutation on Cu2+ coordination |
| Q42980695 | Amyloid beta 1-42 deposits do not lead to Alzheimer's neuritic plaques in aged dogs. |
| Q35773873 | Amyloid beta protein deposition in normal aging has the same characteristics as that in Alzheimer's disease. Predominance of A beta 42(43) and association of A beta 40 with cored plaques |
| Q48617231 | Amyloid beta-protein (Abeta) 1-40 but not Abeta1-42 contributes to the experimental formation of Alzheimer disease amyloid fibrils in rat brain |
| Q35998995 | Amyloid precursor protein processing and A beta42 deposition in a transgenic mouse model of Alzheimer disease |
| Q37247201 | Amyloid precursor protein transgenic mouse models and Alzheimer's disease: understanding the paradigms, limitations, and contributions |
| Q41959077 | Amyloid β Modification: A Key to the Sporadic Alzheimer's Disease? |
| Q28681651 | Amyloid-beta isoform metabolism quantitation by stable isotope-labeled kinetics |
| Q37364324 | Amyloid-beta peptide Abetap3-42 affects early aggregation of full-length Abeta1-42. |
| Q35222076 | Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis |
| Q51748281 | Amyloid-β with isomerized Asp7 cytotoxicity is coupled to protein phosphorylation. |
| Q38289390 | Amylose recognition and ring-size determination of amylomaltase |
| Q37612568 | Analysis of 138 pathogenic mutations in presenilin-1 on the in vitro production of Aβ42 and Aβ40 peptides by γ-secretase |
| Q30476109 | Analysis of beta-amyloid (Abeta) deposition in the temporal lobe in Alzheimer's disease using Fourier (spectral) analysis |
| Q41970463 | Analysis of isoaspartic Acid by selective proteolysis with Asp-N and electron transfer dissociation mass spectrometry |
| Q34095665 | Aspartic acid in the hippocampus: a biomarker for postoperative cognitive dysfunction |
| Q39252529 | Assessing analytical methods to monitor isoAsp formation in monoclonal antibodies |
| Q46335422 | Aβ truncated species: Implications for brain clearance mechanisms and amyloid plaque deposition |
| Q36827322 | Aβ40 has a subtle effect on Aβ42 protofibril formation, but to a lesser degree than Aβ42 concentration, in Aβ42/Aβ40 mixtures |
| Q93060776 | Aβ43 in human Alzheimer's disease: effects of active Aβ42 immunization |
| Q33202614 | BACE1: the beta-secretase enzyme in Alzheimer's disease |
| Q28488690 | Bapineuzumab alters aβ composition: implications for the amyloid cascade hypothesis and anti-amyloid immunotherapy |
| Q35969894 | Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red. |
| Q45969415 | Beta-amyloid precursor protein (APP) and APP-RNA are rapidly affected by glutamate in cultured neurons: selective increase of mRNAs encoding a Kunitz protease inhibitor domain. |
| Q35890955 | Biochemical and morphological characterization of the AβPP/PS/tau triple transgenic mouse model and its relevance to sporadic Alzheimer's disease |
| Q28542628 | Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease |
| Q38016898 | Biochemistry of amyloid β-protein and amyloid deposits in Alzheimer disease |
| Q36346078 | C1q ablation exacerbates amyloid deposition: A study in a transgenic mouse model of ATTRV30M amyloid neuropathy. |
| Q42396970 | CEREBRAL AMYLOID ANGIOPATHY AND ALZHEIMER'S DISEASE. |
| Q38262127 | CHOLESTEROL AND NEURONAL SUSCEPTIBILITY TO BETA-AMYLOID TOXICITY. |
| Q39790508 | Cell-derived soluble oligomers of human amyloid-beta peptides disturb cellular homeostasis and induce apoptosis in primary hippocampal neurons |
| Q53199564 | Cerebral beta amyloid deposition in patients with malignant neoplasms: its prevalence with aging and effects of radiation therapy on vascular amyloid. |
| Q42139423 | Characterization of an antibody that recognizes peptides containing D-β-aspartyl residues. |
| Q36438065 | Characterization of new polyclonal antibodies specific for 40 and 42 amino acid-long amyloid beta peptides: their use to examine the cell biology of presenilins and the immunohistochemistry of sporadic Alzheimer's disease and cerebral amyloid angiop |
| Q42046973 | Charge-based binding of complement component C1q to the Alzheimer amyloid beta-peptide |
| Q28828354 | Chemical and neuropathological analyses of an Alzheimer's disease patient treated with solanezumab |
| Q33969588 | Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets |
| Q90574028 | Chiral checkpoints during protein biosynthesis |
| Q34286933 | Closing in on the amyloid cascade: recent insights into the cell biology of Alzheimer's disease |
| Q42995624 | Collagen fragments in urine derived from bone resorption are highly racemized and isomerized: a biological clock of protein aging with clinical potential |
| Q92082747 | Computational Studies on Water-Catalyzed Mechanisms for Stereoinversion of Glutarimide Intermediates Formed from Glutamic Acid Residues in Aqueous Phase |
| Q35796086 | Conformational mimicry in Alzheimer's disease. Role of apolipoproteins in amyloidogenesis |
| Q42772146 | Covalent structural changes in unfolded GroES that lead to amyloid fibril formation detected by NMR: insight into intrinsically disordered proteins. |
| Q34788544 | D-amino acids in living higher organisms |
| Q41814945 | Deamidation accelerates amyloid formation and alters amylin fiber structure |
| Q36476874 | Deamidation: Differentiation of aspartyl from isoaspartyl products in peptides by electron capture dissociation |
| Q38901019 | Detection, evaluation and minimization of nonenzymatic deamidation in proteomic sample preparation |
| Q41580743 | Deuteration protects asparagine residues against racemization. |
| Q35833877 | Development of a monoclonal antibody specific for the COOH-terminal of beta-amyloid 1-42 and its immunohistochemical reactivity in Alzheimer's disease and related disorders |
| Q38281208 | Differentiating N-terminal aspartic and isoaspartic acid residues in peptides. |
| Q85001526 | Differentiation of α- or β-aspartic isomers in the heptapeptides by the fragments of [M + Na]+ using ion trap tandem mass spectrometry |
| Q45854659 | Diffuse Senile Plaques: Amorphous or Fibrous? |
| Q47147272 | Distinguishing Aspartic and Isoaspartic Acids in Peptides by Several Mass Spectrometric Fragmentation Methods |
| Q50920962 | Distinguishing d- and l-aspartic and isoaspartic acids in amyloid β peptides with ultrahigh resolution ion mobility spectrometry. |
| Q41529132 | Diversity of Amyloid-beta Proteoforms in the Alzheimer's Disease Brain. |
| Q90387038 | Effect of Post-Translational Modifications and Mutations on Amyloid-β Fibrils Dynamics at N Terminus |
| Q40950151 | Effects of the amyloid precursor protein Glu693-->Gln 'Dutch' mutation on the production and stability of amyloid beta-protein |
| Q35043190 | Electron transfer dissociation with supplemental activation to differentiate aspartic and isoaspartic residues in doubly charged peptide cations. |
| Q35809798 | Elevated abeta42 in skeletal muscle of Alzheimer disease patients suggests peripheral alterations of AbetaPP metabolism. |
| Q35631357 | Engineering D-Amino Acid Containing Collagen Like Peptide at the Cleavage Site of Clostridium histolyticum Collagenase for Its Inhibition |
| Q28388148 | Experimental constraints on quaternary structure in Alzheimer's beta-amyloid fibrils |
| Q44601302 | First evidence on induced topological changes in supercoiled DNA by an aluminium d-aspartate complex |
| Q35782745 | Full-length amyloid-beta (1-42(43)) and amino-terminally modified and truncated amyloid-beta 42(43) deposit in diffuse plaques. |
| Q48499322 | Generation of a recombinant Fab antibody reactive with the Alzheimer's disease-related Abeta peptide |
| Q41682728 | Genetic background modifies amyloidosis in a mouse model of ATTR neuropathy. |
| Q35782286 | High levels of circulating beta-amyloid peptide do not cause cerebral beta-amyloidosis in transgenic mice |
| Q35833986 | High tissue content of soluble beta 1-40 is linked to cerebral amyloid angiopathy |
| Q34300357 | Identification of amino acid epimerization and isomerization in crystallin proteins by tandem LC-MS |
| Q42076718 | Identification of aspartic and isoaspartic acid residues in amyloid beta peptides, including Abeta1-42, using electron-ion reactions |
| Q47106292 | Identification of ᴅ-amino acid-containing peptides in human serum |
| Q58765987 | Implications of Metal Binding and Asparagine Deamidation for Amyloid Formation |
| Q30889969 | In vivo amyloid imaging in Alzheimer's disease |
| Q42225476 | In-Source Decay Characterization of Isoaspartate and β-Peptides |
| Q28076999 | Insight of brain degenerative protein modifications in the pathology of neurodegeneration and dementia by proteomic profiling |
| Q37903737 | Insights into Alzheimer disease pathogenesis from studies in transgenic animal models |
| Q30426046 | Integrated proteomic analysis of major isoaspartyl-containing proteins in the urine of wild type and protein L-isoaspartate O-methyltransferase-deficient mice |
| Q52169263 | Interaction of amyloid beta-protein with anionic phospholipids: possible involvement of Lys28 and C-terminus aliphatic amino acids. |
| Q53212845 | Interaction of synthetic Alzheimer beta-protein-derived analogs with aqueous aluminum: a low-field 27Al NMR investigation. |
| Q34509753 | Intracellular mechanisms of amyloid accumulation and pathogenesis in Alzheimer's disease |
| Q35913908 | Intracerebral Injection of Metal-Binding Domain of Aβ Comprising the Isomerized Asp7 Increases the Amyloid Burden in Transgenic Mice |
| Q57721642 | Intravenously Injected Amyloid-β Peptide With Isomerized Asp7 and Phosphorylated Ser8 Residues Inhibits Cerebral β-Amyloidosis in AβPP/PS1 Transgenic Mice Model of Alzheimer's Disease |
| Q33745216 | Iowa variant of familial Alzheimer's disease: accumulation of posttranslationally modified AbetaD23N in parenchymal and cerebrovascular amyloid deposits |
| Q37698598 | Is Alzheimer's disease amyloidosis the result of a repair mechanism gone astray? |
| Q38230389 | Is pathological aging a successful resistance against amyloid-beta or preclinical Alzheimer's disease? |
| Q92210130 | Isomerization of Asp7 in Beta-Amyloid Enhances Inhibition of the α7 Nicotinic Receptor and Promotes Neurotoxicity |
| Q42854197 | Isomerization of Asp7 leads to increased toxic effect of amyloid-β42 on human neuronal cells |
| Q34625892 | Kinetics of isomerization and inversion of aspartate 58 of αA-crystallin peptide mimics under physiological conditions |
| Q73844616 | Lack of interactions between amyloid precursor protein and hydrophilic domains of presenilin 1 and 2 using the yeast two hybrid system |
| Q52330210 | Large-Scale Differentiation and Site Specific Discrimination of Hydroxyproline Isomers by Electron Transfer/Higher-Energy Collision Dissociation (EThcD) Mass Spectrometry. |
| Q37224665 | Localization of D-β-aspartyl residue-containing proteins in various tissues |
| Q42263895 | MAPping the chiral inversion and structural transformation of a metal-tripeptide complex having ni-superoxide dismutase activity |
| Q41131542 | Media from rhabdomyosarcoma and neuroblastoma cell cultures stimulate in vitro aggregation and fibrillization of amyloid beta-protein |
| Q52193864 | Metal cations defibrillize the amyloid beta-protein fibrils. |
| Q43918834 | Microglial activation and beta -amyloid deposit reduction caused by a nitric oxide-releasing nonsteroidal anti-inflammatory drug in amyloid precursor protein plus presenilin-1 transgenic mice. |
| Q88522038 | Modest Static Pressure Can Cause Enteric Nerve Degeneration Through Ectodomain Shedding of Cell Adhesion Molecule 1 |
| Q28389961 | Multiple quantum solid-state NMR indicates a parallel, not antiparallel, organization of beta-sheets in Alzheimer's beta-amyloid fibrils |
| Q37043304 | N-truncated amyloid β (Aβ) 4-42 forms stable aggregates and induces acute and long-lasting behavioral deficits |
| Q33888339 | NACP, the precursor protein of the non-amyloid beta/A4 protein (A beta) component of Alzheimer disease amyloid, binds A beta and stimulates A beta aggregation |
| Q33801986 | Neuropathology and amyloid-β spectrum in a bapineuzumab immunotherapy recipient |
| Q28070156 | Neuropsychiatric Disturbances in Alzheimer's Disease: What Have We Learned from Neuropathological Studies? |
| Q50996852 | Peripherally applied synthetic peptide isoAsp7-Aβ(1-42) triggers cerebral β-amyloidosis. |
| Q91959894 | Pharmacokinetic and Pharmacodynamic Effects of a γ-Secretase Modulator, PF-06648671, on CSF Amyloid-β Peptides in Randomized Phase I Studies |
| Q51766352 | Phosphate-Catalyzed Succinimide Formation from Asp Residues: A Computational Study of the Mechanism. |
| Q57721645 | Phosphorylation of the Amyloid-Beta Peptide Inhibits Zinc-Dependent Aggregation, Prevents Na,K-ATPase Inhibition, and Reduces Cerebral Plaque Deposition |
| Q31035125 | Polymorphic fibril formation by residues 10-40 of the Alzheimer's beta-amyloid peptide |
| Q34154430 | Positive evolutionary selection of an HD motif on Alzheimer precursor protein orthologues suggests a functional role |
| Q41454633 | Posttranslational arginylation of brain proteins |
| Q48133627 | Potential beta PP-processing proteinase activities from Alzheimer's and control brain tissues |
| Q35773537 | Predominant deposition of amyloid-beta 42(43) in plaques in cases of Alzheimer's disease and hereditary cerebral hemorrhage associated with mutations in the amyloid precursor protein gene |
| Q46656882 | Preparation of Amyloid Fibrils Seeded from Brain and Meninges. |
| Q53313818 | Presence of apolipoprotein E on extracellular neurofibrillary tangles and on meningeal blood vessels precedes the Alzheimer beta-amyloid deposition. |
| Q36481949 | Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's disease |
| Q38721567 | Presenilin-1 Targeted Morpholino Induces Cognitive Deficits, Increased Brain Aβ1-42 and Decreased Synaptic Marker PSD-95 in Zebrafish Larvae |
| Q35745836 | Prominent cerebral amyloid angiopathy in transgenic mice overexpressing the london mutant of human APP in neurons. |
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| Q35765178 | Quantitation of amyloid beta-protein (A beta) in the cortex during aging and in Alzheimer's disease. |
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| Q41607465 | Solid-Phase Synthesis and Characterization of N-Terminally Elongated Aβ-3-x -Peptides |
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