The fission yeast RNA binding protein Mmi1 regulates meiotic genes by controlling intron specific splicing and polyadenylation coupled RNA turnover

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The fission yeast RNA binding protein Mmi1 regulates meiotic genes by controlling intron specific splicing and polyadenylation coupled RNA turnover is …
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scholarly articleQ13442814

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P819ADS bibcode2011PLoSO...626804C
P356DOI10.1371/JOURNAL.PONE.0026804
P932PMC publication ID3203177
P698PubMed publication ID22046364
P5875ResearchGate publication ID51761163

P2093author name stringBruce Futcher
Huei-Mei Chen
Janet Leatherwood
P2860cites workA new yeast poly(A) polymerase complex involved in RNA quality controlQ21146099
Rec8p, a meiotic recombination and sister chromatid cohesion phosphoprotein of the Rad21p family conserved from fission yeast to humansQ22009415
The YTH domain is a novel RNA binding domainQ24300052
Functions of the exosome in rRNA, snoRNA and snRNA synthesisQ24529845
Emerging features of mRNA decay in bacteriaQ24539798
Yeast transcripts cleaved by an internal ribozyme provide new insight into the role of the cap and poly(A) tail in translation and mRNA decayQ24548790
Cluster analysis and display of genome-wide expression patternsQ24644463
TRAMP complex enhances RNA degradation by the nuclear exosome component Rrp6Q24646718
The interaction and colocalization of Sam68 with the splicing-associated factor YT521-B in nuclear dots is regulated by the Src family kinase p59(fyn)Q24651533
The cell cycle-regulated genes of Schizosaccharomyces pombeQ24811746
Fitting a mixture model by expectation maximization to discover motifs in biopolymersQ27860556
RNA degradation by the exosome is promoted by a nuclear polyadenylation complexQ27932438
A nuclear 3'-5' exonuclease involved in mRNA degradation interacts with Poly(A) polymerase and the hnRNA protein Npl3pQ27934140
The yeast Rat1 exonuclease promotes transcription termination by RNA polymerase II.Q27934493
Nuclear surveillance and degradation of hypomodified initiator tRNAMet in S. cerevisiaeQ27934543
An extensive network of coupling among gene expression machinesQ29547273
Molecular genetic analysis of fission yeast Schizosaccharomyces pombeQ29547703
Aberrant herpesvirus-induced polyadenylation correlates with cellular messenger RNA destructionQ30863867
Poly(A) tail length control in Saccharomyces cerevisiae occurs by message-specific deadenylation.Q33781517
Utilization of splicing elements and polyadenylation signal elements in the coupling of polyadenylation and last-intron removalQ33958705
The poly(A) tail of mRNAs: bodyguard in eukaryotes, scavenger in bacteriaQ33962914
A synthetic A tail rescues yeast nuclear accumulation of a ribozyme-terminated transcriptQ33983114
Importance of polyadenylation in the selective elimination of meiotic mRNAs in growing S. pombe cells.Q34000165
Replacement of the yeast TRP4 3' untranslated region by a hammerhead ribozyme results in a stable and efficiently exported mRNA that lacks a poly(A) tailQ34364264
Rules of engagement: co-transcriptional recruitment of pre-mRNA processing factorsQ34419716
The transcriptional program of meiosis and sporulation in fission yeast.Q52116421
Negative control contributes to an extensive program of meiotic splicing in fission yeast.Q53675973
Uncoupling of mRNA 3' cleavage and polyadenylation by expression of a hammerhead ribozyme in yeastQ72808458
Polyadenylation of rRNA- and tRNA-based yeast transcripts cleaved by internal ribozyme activityQ73398372
A family of multifunctional thiamine-repressible expression vectors for fission yeastQ73912063
Regulation of the nuclear poly(A)-binding protein by arginine methylation in fission yeastQ79527343
Separate RNA-binding surfaces on the multifunctional La protein mediate distinguishable activities in tRNA maturationQ79787212
Single-allele analysis of transcription kinetics in living mammalian cellsQ84576662
Conditions for the selective synthesis of DNA complementary to template RNAQ93734922
A meiotic gene regulatory cascade driven by alternative fates for newly synthesized transcriptsQ34471007
Accumulation of unstable promoter-associated transcripts upon loss of the nuclear exosome subunit Rrp6p in Saccharomyces cerevisiaeQ34480038
Selective elimination of messenger RNA prevents an incidence of untimely meiosisQ34545114
Red1 promotes the elimination of meiosis-specific mRNAs in vegetatively growing fission yeastQ34699709
Ribonucleases from T2 familyQ34730301
Dynamic repertoire of a eukaryotic transcriptome surveyed at single-nucleotide resolutionQ34779368
A network of multiple regulatory layers shapes gene expression in fission yeast.Q35830167
A small nucleolar RNA:ribozyme hybrid cleaves a nucleolar RNA target in vivo with near-perfect efficiencyQ36376928
Major genetic marker of nidoviruses encodes a replicative endoribonucleaseQ37487223
Polyadenylation-assisted RNA degradation processes in plantsQ37589095
The nuclear poly(A)-binding protein interacts with the exosome to promote synthesis of noncoding small nucleolar RNAsQ38346724
The dhp1(+) gene, encoding a putative nuclear 5'-->3' exoribonuclease, is required for proper chromosome segregation in fission yeastQ38660612
Rna15 interaction with the A-rich yeast polyadenylation signal is an essential step in mRNA 3'-end formationQ39529058
A nuclear surveillance pathway for mRNAs with defective polyadenylation.Q39613458
Stimulation of poly(A) polymerase through a direct interaction with the nuclear poly(A) binding protein allosterically regulated by RNA.Q39790864
The Role of the Poly(A) Sequence in Mammalian Messenger RNQ40084085
Cold-sensitive and caffeine-supersensitive mutants of the Schizosaccharomyces pombe dis genes implicated in sister chromatid separation during mitosisQ41114115
The structure, function and application of the hammerhead ribozymeQ41453347
Poly(A) tail length is controlled by the nuclear poly(A)-binding protein regulating the interaction between poly(A) polymerase and the cleavage and polyadenylation specificity factorQ41806905
A novel function for the U2AF 65 splicing factor in promoting pre-mRNA 3'-end processing.Q41837652
Inactivation of the pre-mRNA cleavage and polyadenylation factor Pfs2 in fission yeast causes lethal cell cycle defectsQ41904654
Requirement of fission yeast Cid14 in polyadenylation of rRNAsQ42150561
Negative regulation of meiotic gene expression by the nuclear poly(a)-binding protein in fission yeast.Q42430473
A complex gene regulatory mechanism that operates at the nexus of multiple RNA processing decisionsQ42634656
A novel poly(A)-binding protein acts as a specificity factor in the second phase of messenger RNA polyadenylationQ45284501
Meiotic DNA breaks associated with recombination in S. pombeQ47847394
Purification, cloning, and characterization of XendoU, a novel endoribonuclease involved in processing of intron-encoded small nucleolar RNAs in Xenopus laevisQ48260845
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P4510describes a project that usesImageQuantQ112270642
P433issue10
P407language of work or nameEnglishQ1860
P304page(s)e26804
P577publication date2011-10-27
P1433published inPLOS OneQ564954
P1476titleThe fission yeast RNA binding protein Mmi1 regulates meiotic genes by controlling intron specific splicing and polyadenylation coupled RNA turnover
P478volume6

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cites work (P2860)
Q37362555A developmentally regulated translational control pathway establishes the meiotic chromosome segregation pattern
Q36060833A dominant role for meiosis-specific 3' RNA processing in controlling expression of a fission yeast cyclin gene
Q36532672A novel RNA-binding mode of the YTH domain reveals the mechanism for recognition of determinant of selective removal by Mmi1.
Q38667249Analysis of Schizosaccharomyces pombe Meiosis
Q61818324CDK contribution to DSB formation and recombination in fission yeast meiosis
Q35814334Canonical Poly(A) Polymerase Activity Promotes the Decay of a Wide Variety of Mammalian Nuclear RNAs.
Q36419788Conserved factor Dhp1/Rat1/Xrn2 triggers premature transcription termination and nucleates heterochromatin to promote gene silencing
Q88634130Controlling nuclear RNA levels
Q35903171Different means, same end-heterochromatin formation by RNAi and RNAi-independent RNA processing factors in fission yeast
Q27935623Effects of the yeast RNA-binding protein Whi3 on the half-life and abundance of CLN3 mRNA and other targets
Q36687330Enhancer of Rudimentary Cooperates with Conserved RNA-Processing Factors to Promote Meiotic mRNA Decay and Facultative Heterochromatin Assembly
Q31140846Genome-Wide Analysis and Functional Characterization of the Polyadenylation Site in Pigs Using RNAseq Data
Q41858295Genome-wide analysis of poly(A) site selection in Schizosaccharomyces pombe
Q35959527Hexanucleotide motifs mediate recruitment of the RNA elimination machinery to silent meiotic genes.
Q34961874Introns regulate gene expression in Cryptococcus neoformans in a Pab2p dependent pathway
Q37379964Long noncoding RNA-based chromatin control of germ cell differentiation: a yeast perspective.
Q34625287Measurements of the impact of 3' end sequences on gene expression reveal wide range and sequence dependent effects
Q89505468Meiotic gene silencing complex MTREC/NURS recruits the nuclear exosome to YTH-RNA-binding protein Mmi1
Q33828505Meiotic long non-coding meiRNA accumulates as a dot at its genetic locus facilitated by Mmi1 and plays as a decoy to lure Mmi1.
Q38639770MhYTP1 and MhYTP2 from Apple Confer Tolerance to Multiple Abiotic Stresses in Arabidopsis thaliana
Q36000122Mmi1 RNA surveillance machinery directs RNAi complex RITS to specific meiotic genes in fission yeast
Q53169114Molecular biology. RNA plays meiotic matchmaker.
Q37682692Mtr4-like protein coordinates nuclear RNA processing for heterochromatin assembly and for telomere maintenance.
Q39070444Multiple Transcriptional and Post-transcriptional Pathways Collaborate to Control Sense and Antisense RNAs of Tf2 Retroelements in Fission Yeast
Q36626011Nuclear RNA surveillance: role of TRAMP in controlling exosome specificity
Q35078209Optimisation of the Schizosaccharomyces pombe urg1 expression system
Q42872039Poly(A) tail-mediated gene regulation by opposing roles of Nab2 and Pab2 nuclear poly(A)-binding proteins in pre-mRNA decay
Q28485193Polyadenylation-dependent control of long noncoding RNA expression by the poly(A)-binding protein nuclear 1
Q57469420Proteomic profiling and functional characterization of post-translational modifications of the fission yeast RNA exosome
Q52599402RNA surveillance by the nuclear RNA exosome: mechanisms and significance.
Q37012974Red5 and three nuclear pore components are essential for efficient suppression of specific mRNAs during vegetative growth of fission yeast.
Q36414986Regulation of mRNA Levels by Decay-Promoting Introns that Recruit the Exosome Specificity Factor Mmi1.
Q41747137Relative contributions of the structural and catalytic roles of Rrp6 in exosomal degradation of individual mRNAs
Q34125334Repression of meiotic genes by antisense transcription and by Fkh2 transcription factor in Schizosaccharomyces pombe
Q28482363Rhn1, a nuclear protein, is required for suppression of meiotic mRNAs in mitotically dividing fission yeast
Q40098938Selective termination of lncRNA transcription promotes heterochromatin silencing and cell differentiation
Q28574340Solution structure of the YTH domain in complex with N6-methyladenosine RNA: a reader of methylated RNA
Q91771241The Nuclear RNA Exosome and Its Cofactors
Q55236864The RNA Exosome Adaptor ZFC3H1 Functionally Competes with Nuclear Export Activity to Retain Target Transcripts.
Q27309189The Zinc-Finger Protein SOP1 Is Required for a Subset of the Nuclear Exosome Functions in Arabidopsis
Q36534273The architecture of the Schizosaccharomyces pombe CCR4-NOT complex
Q37179884The fission yeast MTREC and EJC orthologs ensure the maturation of meiotic transcripts during meiosis.
Q35681747The fission yeast MTREC complex targets CUTs and unspliced pre-mRNAs to the nuclear exosome.
Q35022339The human nuclear poly(a)-binding protein promotes RNA hyperadenylation and decay
Q26825398The long and the short of it: the role of the zinc finger polyadenosine RNA binding protein, Nab2, in control of poly(A) tail length
Q41495422Untimely expression of gametogenic genes in vegetative cells causes uniparental disomy.
Q58694259and mRNAs are novel RNA targets of the Mei2 RNA-binding protein during early meiosis in