Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion

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Expression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion is …
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scholarly articleQ13442814

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P356DOI10.1074/JBC.M113.544338
P932PMC publication ID4140896
P698PubMed publication ID24719328

P2093author name stringThomas N Wight
Kathleen R Braun
Inkyung Kang
Dong Won Yoon
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Retrovirally mediated overexpression of versican v3 by arterial smooth muscle cells induces tropoelastin synthesis and elastic fiber formation in vitro and in neointima after vascular injuryQ77743543
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Retrovirally mediated overexpression of versican v3 reverses impaired elastogenesis and heightened proliferation exhibited by fibroblasts from Costello syndrome and Hurler disease patientsQ34286189
Proinflammatory stimuli regulate endothelial hyaluronan expression and CD44/HA-dependent primary adhesionQ34451438
Neointima formed by arterial smooth muscle cells expressing versican variant V3 is resistant to lipid and macrophage accumulationQ35069763
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Organization of hyaluronan and versican in the extracellular matrix of human fibroblasts treated with the viral mimetic poly I:C.Q37389406
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Formation of hyaluronan- and versican-rich pericellular matrix is required for proliferation and migration of vascular smooth muscle cellsQ38326238
Stimulation of hyaluronan synthesis by tumor necrosis factor-alpha is mediated by the p50/p65 NF-kappa B complex in MRC-5 myofibroblastsQ38328148
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Regulation of renal proximal tubular epithelial cell hyaluronan generation: implications for diabetic nephropathyQ43586121
beta 1-Integrin-mediated glioma cell adhesion and free radical-induced apoptosis are regulated by binding to a C-terminal domain of PG-M/versicanQ43862899
Overexpression of the V3 variant of versican alters arterial smooth muscle cell adhesion, migration, and proliferation in vitro.Q43864458
Endoplasmic reticulum stress induces hyaluronan deposition and leukocyte adhesionQ44572804
Pro- and anti-inflammatory factors cooperate to control hyaluronan synthesis in lung fibroblastsQ44756854
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Regulation of MDR1 expression and drug resistance by a positive feedback loop involving hyaluronan, phosphoinositide 3-kinase, and ErbB2.Q46398274
Negative regulation of monocyte adhesion to arterial elastic laminae by signal regulatory protein alpha and Src homology 2 domain-containing protein-tyrosine phosphatase-1.Q46701034
P4510describes a project that usesImageJQ1659584
P433issue22
P407language of work or nameEnglishQ1860
P304page(s)15393-15404
P577publication date2014-04-09
P1433published inJournal of Biological ChemistryQ867727
P1476titleExpression of versican V3 by arterial smooth muscle cells alters tumor growth factor β (TGFβ)-, epidermal growth factor (EGF)-, and nuclear factor κB (NFκB)-dependent signaling pathways, creating a microenvironment that resists monocyte adhesion
P478volume289

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cites work (P2860)
Q87939445A role for proteoglycans in vascular disease
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Q91712036Versican-A Critical Extracellular Matrix Regulator of Immunity and Inflammation

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