Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer

scientific article

Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer is …
instance of (P31):
scholarly articleQ13442814
retracted paperQ45182324

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P819ADS bibcode2011PLoSO...627684H
P356DOI10.1371/JOURNAL.PONE.0027684
P932PMC publication ID3215738
P698PubMed publication ID22110720
P5875ResearchGate publication ID51824259

P2093author name stringJie Shen
Feng Wang
Ling Xu
Rong Wan
AiWu Ke
ChuanYong Guo
GuoYong Hu
LiJuan Yang
ShanShan He
XingPeng Wang
XuanFu Xu
P2860cites workDNA methylation of multiple tumor-related genes in association with overexpression of DNA methyltransferase 1 (DNMT1) during multistage carcinogenesis of the pancreas.Q53348394
Molecular progression of promoter methylation in intraductal papillary mucinous neoplasms (IPMN) of the pancreas.Q53382633
The fundamental role of epigenetic events in cancerQ56421597
Chromosomal Instability and Tumors Promoted by DNA HypomethylationQ63253103
Role of DNA 5-methylcytosine transferase in cell transformation by fosQ22008665
The human DNA methyltransferases (DNMTs) 1, 3a and 3b: coordinate mRNA expression in normal tissues and overexpression in tumorsQ22010018
MicroRNA-29 family reverts aberrant methylation in lung cancer by targeting DNA methyltransferases 3A and 3BQ24564757
The GLI gene encodes a nuclear protein which binds specific sequences in the human genomeQ24598690
MicroRNA-143 targets DNA methyltransferases 3A in colorectal cancerQ24643430
Worms gang up on bacteriaQ27860588
Widespread requirement for Hedgehog ligand stimulation in growth of digestive tract tumoursQ28206040
The hedgehog signaling networkQ28209337
Genomic characterization of Gli-activator targets in sonic hedgehog-mediated neural patterningQ28507384
Hedgehog is an early and late mediator of pancreatic cancer tumorigenesisQ29614405
DNA methylation, methyltransferases, and cancerQ30993657
Differential mRNA expression of the human DNA methyltransferases (DNMTs) 1, 3a and 3b during the G(0)/G(1) to S phase transition in normal and tumor cellsQ33689112
DNA methylation-mediated down-regulation of DNA methyltransferase-1 (DNMT1) is coincident with, but not essential for, global hypomethylation in human placentaQ33744584
Methylation of the SPARC gene promoter and its clinical implication in pancreatic cancerQ33820209
Identification of RegIV as a novel GLI1 target gene in human pancreatic cancer.Q33873519
Transcriptional suppression of mir-29b-1/mir-29a promoter by c-Myc, hedgehog, and NF-kappaB.Q34070947
Reduction of pancreatic acinar cell tumor multiplicity in Dnmt1 hypomorphic miceQ35020444
MicroRNA-29b induces global DNA hypomethylation and tumor suppressor gene reexpression in acute myeloid leukemia by targeting directly DNMT3A and 3B and indirectly DNMT1.Q37262433
Hedgehog target genes: mechanisms of carcinogenesis induced by aberrant hedgehog signaling activationQ37622323
Activation of the hedgehog-signaling pathway in human cancer and the clinical implicationsQ37638143
CD151 amplifies signaling by integrin α6β1 to PI3K and induces the epithelial-mesenchymal transition in HCC cellsQ39592399
Down-regulated microRNA-152 induces aberrant DNA methylation in hepatitis B virus-related hepatocellular carcinoma by targeting DNA methyltransferase 1.Q39688414
Gli1 contributes to the invasiveness of pancreatic cancer through matrix metalloproteinase-9 activationQ39992254
Genetic disruption of cytosine DNA methyltransferase enzymes induces chromosomal instability in human cancer cellsQ40365867
Regulation of DNA methyltransferase 1 by the pRb/E2F1 pathwayQ40427781
Increased protein stability causes DNA methyltransferase 1 dysregulation in breast cancer.Q40448993
Regulation of DNA methylation by the Ras signaling pathwayQ41345997
Blockade of hedgehog signaling inhibits pancreatic cancer invasion and metastases: a new paradigm for combination therapy in solid cancersQ42713409
DNA methyltransferase is a downstream effector of cellular transformation triggered by simian virus 40 large T antigenQ42817479
P275copyright licenseCreative Commons Attribution 4.0 InternationalQ20007257
P6216copyright statuscopyrightedQ50423863
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectpancreatic cancerQ212961
P304page(s)e27684
P577publication date2011-11-14
P1433published inPLOS OneQ564954
P1476titleExpression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancer
P478volume6

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