GLI2 cooperates with ZEB1 for transcriptional repression of CDH1 expression in human melanoma cells

scientific article published on 12 August 2013

GLI2 cooperates with ZEB1 for transcriptional repression of CDH1 expression in human melanoma cells is …
instance of (P31):
scholarly articleQ13442814

External links are
P356DOI10.1111/PCMR.12149
P698PubMed publication ID23890107
P5875ResearchGate publication ID253331894

P2093author name stringCristèle Gilbert
Alain Mauviel
Delphine Javelaud
Véronique Marsaud
Antonio Postigo
Carole Y Perrot
P2860cites workGli proteins in development and diseaseQ37908115
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Expression of microphthalmia-associated transcription factor (MITF), which is critical for melanoma progression, is inhibited by both transcription factor GLI2 and transforming growth factor-β.Q38326193
Hedgehog-GLI signaling drives self-renewal and tumorigenicity of human melanoma-initiating cellsQ39325781
GLI2 and M-MITF transcription factors control exclusive gene expression programs and inversely regulate invasion in human melanoma cellsQ39498508
Transforming growth factor-beta activation promotes genetic context-dependent invasion of immortalized melanocytesQ39976268
Differential regulation of epithelial and mesenchymal markers by deltaEF1 proteins in epithelial mesenchymal transition induced by TGF-betaQ41807406
Metastatic potential of melanomas defined by specific gene expression profiles with no BRAF signatureQ42804978
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Whole genome amplification of sodium bisulfite-treated DNA allows the accurate estimate of methylated cytosine density in limited DNA resources.Q51909381
Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone MetastasisQ54976432
A previously unidentified amino-terminal domain regulates transcriptional activity of wild-type and disease-associated human GLI2Q24306603
TWIST1 is an ERK1/2 effector that promotes invasion and regulates MMP-1 expression in human melanoma cellsQ24594566
Mammalian Krüppel-Like Factors in Health and DiseasesQ24612560
In vivo identification of tumor- suppressive PTEN ceRNAs in an oncogenic BRAF-induced mouse model of melanomaQ24629400
Regulation of Smad signaling through a differential recruitment of coactivators and corepressors by ZEB proteinsQ24677861
The transcription factor snail is a repressor of E-cadherin gene expression in epithelial tumour cellsQ28143877
Snail induction of epithelial to mesenchymal transition in tumor cells is accompanied by MUC1 repression and ZEB1 expressionQ28216833
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Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?Q29547559
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TGF-beta-RI kinase inhibitor SD-208 reduces the development and progression of melanoma bone metastasesQ30429041
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Cloning of the human GLI2 Promoter: transcriptional activation by transforming growth factor-beta via SMAD3/beta-catenin cooperationQ33553631
ZEB, a vertebrate homolog of Drosophila Zfh-1, is a negative regulator of muscle differentiationQ33886951
Involvement of members of the cadherin superfamily in cancerQ33899441
Expression of DNMT1 and DNMT3a are regulated by GLI1 in human pancreatic cancerQ34081717
Cancer stem cells versus phenotype-switching in melanomaQ34132378
Overlapping activities of TGF-β and Hedgehog signaling in cancer: therapeutic targets for cancer treatment.Q34444903
Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.Q34516142
E-cadherin expression in melanoma cells restores keratinocyte-mediated growth control and down-regulates expression of invasion-related adhesion receptorsQ35810162
G9a interacts with Snail and is critical for Snail-mediated E-cadherin repression in human breast cancerQ35858016
Melanocytes and the microphthalmia transcription factor networkQ35965847
Slug expression during melanoma progressionQ36044631
Gli1 acts through Snail and E-cadherin to promote nuclear signaling by beta-cateninQ36444506
Pathology of melanomaQ36445925
Spatiotemporal regulation of epithelial-mesenchymal transition is essential for squamous cell carcinoma metastasisQ36467995
Transforming growth factor-beta in cutaneous melanomaQ37143532
P433issue6
P304page(s)861-873
P577publication date2013-08-12
P1433published inPigment Cell & Melanoma ResearchQ762851
P1476titleGLI2 cooperates with ZEB1 for transcriptional repression of CDH1 expression in human melanoma cells
P478volume26

Reverse relations

cites work (P2860)
Q98906787Large-scale pan-cancer analysis reveals broad prognostic association between TGF-β ligands, not Hedgehog, and GLI1/2 expression in tumors
Q38299938Melanoma cells revive an embryonic transcriptional network to dictate phenotypic heterogeneity.
Q21284811Melanoma: from melanocyte to genetic alterations and clinical options
Q56428911Molecular pathology of cutaneous melanoma
Q38925675The GRHL2/ZEB Feedback Loop-A Key Axis in the Regulation of EMT in Breast Cancer.
Q38878911The role of phenotypic plasticity in the escape of cancer cells from targeted therapy.
Q37615918Therapeutic implications of cellular and molecular biology of cancer stem cells in melanoma
Q34221697Thrombospondin 1 promotes an aggressive phenotype through epithelial-to-mesenchymal transition in human melanoma
Q36967309Transforming growth factor β1 antagonizes the transcription, expression and vascular signaling of guanylyl cyclase/natriuretic peptide receptor A - role of δEF1.

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