Working at the cutting edge: the creation of allosteric ribozymes

scientific article

Working at the cutting edge: the creation of allosteric ribozymes is …
instance of (P31):
review articleQ7318358
scholarly articleQ13442814

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P356DOI10.1016/S0969-2126(00)00517-7
P698PubMed publication ID11080644

P2093author name stringTaira K
Kuwabara T
Warashina M
P2860cites workAllosteric selection of ribozymes that respond to the second messengers cGMP and cAMP.Q52172539
Design of allosteric hammerhead ribozymes activated by ligand-induced structure stabilizationQ58001471
The hairpin ribozyme: structure, assembly and catalysisQ59444016
Training ribozymes to switchQ73133428
Chemical and enzymatic probing of effector-mediated changes in the conformation of a maxizymeQ73904860
Oncogene inactivation in a mouse modelQ74203674
Extremely high and specific activity of DNA enzymes in cells with a Philadelphia chromosomeQ74659517
An allosteric hammerhead ribozymeQ74677248
Ribozymes: the hammerhead swings into actionQ74776622
Formation of a catalytically active dimer by tRNA(Val)-driven short ribozymesQ77463633
The Hydrolysis of RNA: From Theoretical Calculations to the Hammerhead Ribozyme-Mediated Cleavage of RNAQ77646670
In vitro selection of an allosteric ribozyme that transduces analytes to ampliconsQ77910082
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22Q28265748
Factors governing the activity in vivo of ribozymes transcribed by RNA polymerase III.Q33652811
Nucleic acid enzymesQ33652967
Structure, folding and catalysis of the small nucleolytic ribozymesQ33653373
Nucleic acid molecular switchesQ33771875
RNA structure, metal ions, and catalysisQ33796461
Differences among mechanisms of ribozyme-catalyzed reactionsQ34024322
Allosterically controllable maxizymes cleave mRNA with high efficiency and specificityQ34073726
Characterization of several kinds of dimer minizyme: simultaneous cleavage at two sites in HIV-1 tat mRNA by dimer minizymesQ34599861
Comparison of the specificities and catalytic activities of hammerhead ribozymes and DNA enzymes with respect to the cleavage of BCR-ABL chimeric L6 (b2a2) mRNAQ34632456
Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1.Q34719998
Engineering precision RNA molecular switchesQ36444768
Effective inhibition of influenza virus production in cultured cells by external guide sequences and ribonuclease P.Q36486121
tRNAVal-heterodimeric maxizymes with high potential as geneinactivating agents: simultaneous cleavage at two sites in HIV-1 Tat mRNA in cultured cellsQ37162170
Rational design of allosteric ribozymesQ38345361
Allosteric regulation of a ribozyme activity through ligand-induced conformational changeQ39724544
Maxizymes, novel allosterically controllable ribozymes, can be designed to cleave various substratesQ40675962
A novel allosterically trans-activated ribozyme, the maxizyme, with exceptional specificity in vitro and in vivoQ40989781
Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiationQ41038113
The structure, function and application of the hammerhead ribozymeQ41453347
Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursorsQ45887644
P433issue11
P407language of work or nameEnglishQ1860
P921main subjectribozymeQ205858
P304page(s)R207-12
P577publication date2000-11-01
P1433published inStructureQ15709970
P1476titleWorking at the cutting edge: the creation of allosteric ribozymes
P478volume8

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cites work (P2860)
Q42099510MNAzymes, a versatile new class of nucleic acid enzymes that can function as biosensors and molecular switches
Q40716225Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells
Q33939807Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cells

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