Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells

scientific article published on 30 January 2001

Relationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells is …
instance of (P31):
scholarly articleQ13442814

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P356DOI10.1074/JBC.M010570200
P698PubMed publication ID11278700
P5875ResearchGate publication ID12054210

P2093author name stringTaira K
Toda H
Kato Y
Kuwabara T
Warashina M
P2860cites workIdentification of eIF2Bgamma and eIF2gamma as cofactors of hepatitis C virus internal ribosome entry site-mediated translation using a functional genomics approachQ22254630
The role of exportin-t in selective nuclear export of mature tRNAsQ24533485
Chloroplast ribonuclease P does not utilize the ribozyme-type pre-tRNA cleavage mechanismQ28143182
The RNA moiety of ribonuclease P is the catalytic subunit of the enzymeQ28262778
Identification of a nuclear export receptor for tRNAQ28265348
In vitro splicing of the ribosomal RNA precursor of tetrahymena: Involvement of a guanosine nucleotide in the excision of the intervening sequenceQ29302322
BCR first exon sequences specifically activate the BCR/ABL tyrosine kinase oncogene of Philadelphia chromosome-positive human leukemiasQ30195698
Tethering ribozymes to a retroviral packaging signal for destruction of viral RNA.Q30466758
A further investigation and reappraisal of the thio effect in the cleavage reaction catalyzed by a hammerhead ribozymeQ33621005
Structure and function of the hairpin ribozymeQ33861637
Differences among mechanisms of ribozyme-catalyzed reactionsQ34024322
Allosterically controllable maxizymes cleave mRNA with high efficiency and specificityQ34073726
Working at the cutting edge: the creation of allosteric ribozymesQ34083734
Allosterically controllable ribozymes with biosensor functionsQ34096459
Detailed analysis of stem I and its 5' and 3' neighbor regions in the trans-acting HDV ribozymeQ34692128
Intracellular immunization of human fetal cord blood stem/progenitor cells with a ribozyme against human immunodeficiency virus type 1.Q34719998
Kinetic characterization of intramolecular and intermolecular hammerhead RNAs with stem II deletionsQ35607590
Small catalytic RNAsQ35671068
RNA-protein hybrid ribozymes that efficiently cleave any mRNA independently of the structure of the target RNAQ35886262
Hammerhead ribozymes: importance of stem-loop II for activityQ36444559
Effective inhibition of influenza virus production in cultured cells by external guide sequences and ribonuclease P.Q36486121
Phenotypic conversion of drug-resistant bacteria to drug sensitivityQ36543088
Minimal sequence requirements for ribozyme activity.Q37074527
tRNAVal-heterodimeric maxizymes with high potential as geneinactivating agents: simultaneous cleavage at two sites in HIV-1 Tat mRNA in cultured cellsQ37162170
Inhibition of human immunodeficiency virus type 1 expression by a hairpin ribozymeQ37298055
Investigation of the proposed interdomain ribose zipper in hairpin ribozyme cleavage using 2'-modified nucleosidesQ38311891
Selected classes of minimised hammerhead ribozyme have very high cleavage rates at low Mg2+ concentrationQ38324842
Delta ribozyme has the ability to cleave in transan mRNAQ38328786
Maxizymes, novel allosterically controllable ribozymes, can be designed to cleave various substratesQ40675962
A novel allosterically trans-activated ribozyme, the maxizyme, with exceptional specificity in vitro and in vivoQ40989781
Distinct roles of the co-activators p300 and CBP in retinoic-acid-induced F9-cell differentiationQ41038113
The structure, function and application of the hammerhead ribozymeQ41453347
Substrate specificity of delta ribozyme cleavageQ41941431
Reversible cleavage and ligation of hepatitis delta virus RNA.Q43609591
General acid-base catalysis in the mechanism of a hepatitis delta virus ribozymeQ45744207
Control of the functional activity of an antisense RNA by a tetracycline-responsive derivative of the human U6 snRNA promoterQ45866094
Ribozyme-mediated repair of sickle beta-globin mRNAs in erythrocyte precursorsQ45887644
Evidence for helical unwinding of an RNA substrate by the RNA enzyme RNase P: use of an interstrand disulfide crosslink in substrate.Q52171339
Selection of guide sequences that direct efficient cleavage of mRNA by human ribonuclease P.Q52514314
External Guide Sequences for an RNA EnzymeQ54709972
Non-enzymatic cleavage and ligation of RNAs complementary to a plant virus satellite RNAQ59066021
P433issue18
P407language of work or nameEnglishQ1860
P921main subjectribozymeQ205858
P304page(s)15378-15385
P577publication date2001-01-30
P1433published inJournal of Biological ChemistryQ867727
P1476titleRelationships between the activities in vitro and in vivo of various kinds of ribozyme and their intracellular localization in mammalian cells
P478volume276

Reverse relations

cites work (P2860)
Q33184078A functional gene discovery in the Fas-mediated pathway to apoptosis by analysis of transiently expressed randomized hybrid-ribozyme libraries
Q42812083A major functional difference between the mouse and human ARF tumor suppressor proteins
Q33201845A self-processing ribozyme cassette: utility against human papillomavirus 11 E6/E7 mRNA and hepatitis B virus
Q34018226Cross-clade inhibition of HIV-1 replication and cytopathology by using RNase P-associated external guide sequences
Q41946566Delta ribozyme benefits from a good stability in vitro that becomes outstanding in vivo
Q31116966Development and comparison of procedures for the selection of delta ribozyme cleavage sites within the hepatitis B virus
Q90065437Development of a minigenome cassette for Lettuce necrotic yellows virus: A first step in rescuing a plant cytorhabdovirus
Q35781634Disruption of dengue virus transmission by mosquitoes
Q27488865Effective suppression of Dengue fever virus in mosquito cell cultures using retroviral transduction of hammerhead ribozymes targeting the viral genome
Q40539253Efficacy and mode of action of hammerhead and hairpin ribozymes against various HIV-1 target sites
Q44597512Efficient inhibition of β‐secretase gene expression in HEK293 cells by tRNAVal‐driven and CTE‐helicase associated hammerhead ribozymes
Q40407911Endogenously expressed multimeric self-cleaving hammerhead ribozymes ablate mutant collagen in cellulo
Q30437704FRNK expression promotes smooth muscle cell maturation during vascular development and after vascular injury
Q43207477Functional characterization of the SOFA delta ribozyme
Q33217148Gene discovery by ribozyme and siRNA libraries
Q41827296Gene targeting in the Gram-Positive bacterium Lactococcus lactis, using various delta ribozymes
Q24794819Group I aptazymes as genetic regulatory switches
Q54526305HIV-1 TAR as anchoring site for optimized catalytic RNAs.
Q37672325Hairpin Ribozyme Genes Curtail Alcohol Drinking: from Rational Design to in vivo Effects in the Rat
Q34837666Hammerhead ribozymes for target validation
Q40701723Identification of a caspase 3-independent role of pro-apoptotic factor Bak in TNF-alpha-induced apoptosis
Q30833048Identification of genes by hybrid ribozymes that couple cleavage activity with the unwinding activity of an endogenous RNA helicase
Q56765488Identification of genes that function in the TNF-alpha-mediated apoptotic pathway using randomized hybrid ribozyme libraries
Q27491032Investigating a New Generation of Ribozymes in Order to Target HCV
Q38968316Ligand-dependent ribozymes
Q40753324Long-term RNase P-mediated inhibition of HIV-1 replication and pathogenesis
Q33891817Measurements of weak interactions between truncated substrates and a hammerhead ribozyme by competitive kinetic analyses: implications for the design of new and efficient ribozymes with high sequence specificity
Q28580547NADPH oxidase is involved in prostaglandin F2alpha-induced hypertrophy of vascular smooth muscle cells: induction of NOX1 by PGF2alpha
Q35552101Ribozyme-based gene-inactivation systems require a fine comprehension of their substrate specificities; the case of delta ribozyme
Q35107854Ribozymes: recent advances in the development of RNA tools
Q34460403Short hairpin type of dsRNAs that are controlled by tRNA(Val) promoter significantly induce RNAi-mediated gene silencing in the cytoplasm of human cells
Q33939807Significantly higher activity of a cytoplasmic hammerhead ribozyme than a corresponding nuclear counterpart: engineered tRNAs with an extended 3' end can be exported efficiently and specifically to the cytoplasm in mammalian cells
Q33986945Silencing of SPC2 expression using an engineered delta ribozyme in the mouse betaTC-3 endocrine cell line
Q44542544Specific hammerhead ribozymes reduce synthesis of cation-independent mannose 6-phosphate receptor mRNA and protein
Q34236714Targeting mortalin using conventional and RNA-helicase-coupled hammerhead ribozymes
Q52087288Use of a randomized hybrid ribozyme library for identification of genes involved in muscle differentiation.