| Q57831579 | 17 Proteins from Psychrophiles |
| Q92635303 | A New Cold-Adapted and Salt-Tolerant Glutathione Reductase from Antarctic Psychrophilic Bacterium Psychrobacter sp. and Its Resistance to Oxidation |
| Q57059043 | A Novel Cold-Adapted Leucine Dehydrogenase from Antarctic Sea-Ice Bacterium sp. ANT178 |
| Q92815650 | A Novel Cold-Adapted and Salt-Tolerant RNase R from Antarctic Sea-Ice Bacterium Psychrobacter sp. ANT206 |
| Q43021432 | A cold-active and thermostable alcohol dehydrogenase of a psychrotorelant from Antarctic seawater, Flavobacterium frigidimaris KUC-1. |
| Q30398537 | A comparative study of cold- and warm-adapted Endonucleases A using sequence analyses and molecular dynamics simulations |
| Q35588539 | A comprehensive alanine-scanning mutagenesis study reveals roles for salt bridges in the structure and activity of Pseudomonas aeruginosa elastase |
| Q34639870 | Activation energy of extracellular enzymes in soils from different biomes |
| Q51033886 | Activity enhancement of Candida antarctica lipase B by flexibility modulation in helix region surrounding the active site. |
| Q43032946 | Activity, stability and flexibility in glycosidases adapted to extreme thermal environments |
| Q43032163 | Activity-stability relationships in extremophilic enzymes |
| Q40098422 | Adaptation to extreme environments: macromolecular dynamics in bacteria compared in vivo by neutron scattering |
| Q44563885 | Amino acid sequence of the cold-active alkaline phosphatase from Atlantic cod (Gadus morhua). |
| Q57041782 | Antarctic marine ciliates under stress: superoxide dismutases from the psychrophilic Euplotes focardii are cold-active yet heat tolerant enzymes |
| Q27704308 | Biochemical characterization and structural analysis of a new cold-active and salt-tolerant esterase from the marine bacterium Thalassospira sp |
| Q56950252 | Biochemical characterization of a S-glutathionylated carbonic anhydrase isolated from gills of the Antarctic icefish Chionodraco hamatus |
| Q37898189 | Biotechnological uses of enzymes from psychrophiles |
| Q36746823 | Biphenyl dioxygenase from an arctic isolate is not cold adapted. |
| Q37104855 | Characterization of a New Cold-Adapted and Salt-Activated Polysaccharide Lyase Family 7 Alginate Lyase from Pseudoalteromonas sp. SM0524 |
| Q48301597 | Cloning of cold-active alkaline phosphatase gene of a psychrophile, Shewanella sp., and expression of the recombinant enzyme |
| Q64080265 | Cloning, Expression, and Characterization of a Psychrophilic Glucose 6-Phosphate Dehydrogenase from sp. PAMC 26621 |
| Q56927536 | Coding genes and molecular structures of the diffusible signalling proteins (pheromones) of the polar ciliate, Euplotes nobilii |
| Q37152850 | Cold adaptation of zinc metalloproteases in the thermolysin family from deep sea and arctic sea ice bacteria revealed by catalytic and structural properties and molecular dynamics: new insights into relationship between conformational flexibility an |
| Q34951584 | Cold adaptation, ca2+ dependency and autolytic stability are related features in a highly active cold-adapted trypsin resistant to autoproteolysis engineered for biotechnological applications |
| Q54354724 | Cold adaptation: structural and functional characterizations of psychrophilic and mesophilic acetate kinase. |
| Q64081905 | Cold-Adapted Glutathione S-Transferases from Antarctic Psychrophilic Bacterium sp. ANT108: Heterologous Expression, Characterization, and Oxidative Resistance |
| Q43029519 | Cold-active citrate synthase: mutagenesis of active-site residues |
| Q48086357 | Cold-active winter rye glucanases with ice-binding capacity. |
| Q44040013 | Cold-adaptation mechanism of mutant enzymes of 3-isopropylmalate dehydrogenase from Thermus thermophilus |
| Q39490316 | Cold-adapted beta-galactosidase from the Antarctic psychrophile Pseudoalteromonas haloplanktis |
| Q57087406 | Cold-adapted features of arginine kinase from the deep-sea clam Calyptogena kaikoi |
| Q39410680 | Cold-adapted proteases as an emerging class of therapeutics |
| Q43018776 | Comparative sequence and structure analysis reveal features of cold adaptation of an enzyme in the thermolysin family |
| Q43021989 | Comparative studies of endonuclease I from cold-adapted Vibrio salmonicida and mesophilic Vibrio cholerae. |
| Q50600157 | Comparative thermal unfolding study of psychrophilic and mesophilic subtilisin-like serine proteases by molecular dynamics simulations. |
| Q34052344 | Comparative void-volume analysis of psychrophilic and mesophilic enzymes: Structural bioinformatics of psychrophilic enzymes reveals sources of core flexibility |
| Q46279823 | Complementary Proteomic and Biochemical Analysis of Peptidases in Lobster Gastric Juice Uncovers the Functional Role of Individual Enzymes in Food Digestion |
| Q95840365 | Computer simulations explain the anomalous temperature optimum in a cold-adapted enzyme |
| Q46411708 | Conserved functions of the trigger loop and Gre factors in RNA cleavage by bacterial RNA polymerases. |
| Q22065745 | Coping with cold: the genome of the versatile marine Antarctica bacterium Pseudoalteromonas haloplanktis TAC125 |
| Q36260995 | Crystal Structure and Functional Characterization of an Esterase (EaEST) from Exiguobacterium antarcticum |
| Q58091199 | Crystal structure and functional characterization of a cold-active acetyl xylan esterase (PbAcE) from psychrophilic soil microbe Paenibacillus sp |
| Q27649973 | Crystal structure of a cold-adapted class C beta-lactamase |
| Q27650778 | Crystal structure of the cold-active aminopeptidase from Colwellia psychrerythraea, a close structural homologue of the human bifunctional leukotriene A4 hydrolase |
| Q30385217 | Defying the activity-stability trade-off in enzymes: taking advantage of entropy to enhance activity and thermostability. |
| Q48375636 | Determination of kinetics and heat of hydrolysis for non-homogenous substrate by isothermal calorimetry |
| Q28077585 | Discovery, Molecular Mechanisms, and Industrial Applications of Cold-Active Enzymes |
| Q43022643 | Diversity and enzyme properties of protease-producing bacteria isolated from sub-Antarctic sediments of Isla de Los Estados, Argentina |
| Q77221526 | Dual effects of an extra disulfide bond on the activity and stability of a cold-adapted alpha-amylase |
| Q33215680 | Energetics of substrate binding and catalysis by class 1 (glycosylhydrolase family 47) alpha-mannosidases involved in N-glycan processing and endoplasmic reticulum quality control |
| Q38296073 | Engineering the properties of a cold active enzyme through rational redesign of the active site |
| Q35106357 | Enzyme Reactor Design Under Thermal Inactivation |
| Q43600540 | Enzyme activity determination on macromolecular substrates by isothermal titration calorimetry: application to mesophilic and psychrophilic chitinases |
| Q28829953 | Enzyme surface rigidity tunes the temperature dependence of catalytic rates |
| Q43192436 | Erroneous Arrhenius: modified arrhenius model best explains the temperature dependence of ectotherm fitness |
| Q30374943 | Exploring local flexibility/rigidity in psychrophilic and mesophilic carbonic anhydrases. |
| Q43977250 | Exploring the role of a glycine cluster in cold adaptation of an alkaline phosphatase |
| Q57104995 | Extreme catalysts from low-temperature environments |
| Q54339109 | Fluorescence studies on the stability, flexibility and substrate-induced conformational changes of acetate kinases from psychrophilic and mesophilic bacteria. |
| Q40727064 | Free Energy Diagram for the Heterogeneous Enzymatic Hydrolysis of Glycosidic Bonds in Cellulose. |
| Q38935292 | Functional diversity of Teleost arylalkylamine N-acetyltransferase-2: is the timezyme evolution driven by habitat temperature? |
| Q27335166 | Functional motions of Candida antarctica lipase B: a survey through open-close conformations |
| Q58878207 | Gluconeogenic pathway does not display metabolic cold adaptation in liver of Antarctic notothenioid fish |
| Q50287948 | Glutamine Hydrolysis by Imidazole Glycerol Phosphate Synthase Displays Temperature Dependent Allosteric Activation |
| Q56395502 | Homologous yeast lipases/acyltransferases exhibit remarkable cold-active properties |
| Q36850231 | Identification of a long-range protein network that modulates active site dynamics in extremophilic alcohol dehydrogenases |
| Q35973150 | Improving the Thermostability and Activity of a Thermophilic Subtilase by Incorporating Structural Elements of Its Psychrophilic Counterpart |
| Q45304449 | Increased flexibility as a strategy for cold adaptation: a comparative molecular dynamics study of cold- and warm-active uracil DNA glycosylase |
| Q34457583 | Increasing activity and thermal resistance of Bacillus gibsonii alkaline protease (BgAP) by directed evolution |
| Q84909170 | Interaction of DNA topoisomerase 1 with DNA intermediates and proteins of base excision repair |
| Q37417049 | Interplay between the trigger loop and the F loop during RNA polymerase catalysis |
| Q38835377 | Investigating the effect of gallium curcumin and gallium diacetylcurcumin complexes on the structure, function and oxidative stability of the peroxidase enzyme and their anticancer and antibacterial activities |
| Q42808730 | Kinetic and structural optimization to catalysis at low temperatures in a psychrophilic cellulase from the Antarctic bacterium Pseudoalteromonas haloplanktis |
| Q36962847 | Kinetic and thermodynamic studies of peptidyltransferase in ribosomes from the extreme thermophile Thermus thermophilus |
| Q36679373 | Life at low temperatures: is disorder the driving force? |
| Q34785612 | Low-temperature extremophiles and their applications |
| Q39739558 | Metabolic enzymes from psychrophilic bacteria: challenge of adaptation to low temperatures in ornithine carbamoyltransferase from Moritella abyssi |
| Q35856470 | Metagenomics as a Tool for Enzyme Discovery: Hydrolytic Enzymes from Marine-Related Metagenomes |
| Q44700293 | Modulation of activity of NADH oxidase from Thermus thermophilus through change in flexibility in the enzyme active site induced by Hofmeister series anions |
| Q33908295 | Molecular Cloning and Optimization for High Level Expression of Cold-Adapted Serine Protease from Antarctic Yeast Glaciozyma antarctica PI12 |
| Q34514445 | Molecular analysis of the gene encoding a novel cold-adapted chitinase (ChiB) from a marine bacterium, Alteromonas sp. strain O-7. |
| Q30331519 | Molecular basis of cold adaptation. |
| Q42072740 | Molecular chaperone accumulation as a function of stress evidences adaptation to high hydrostatic pressure in the piezophilic archaeon Thermococcus barophilus. |
| Q62570930 | Molecular cold-adaptation: Comparative analysis of two homologous families of psychrophilic and mesophilic signal proteins of the protozoan ciliate,Euplotes |
| Q31030886 | Molecular dynamics of mesophilic-like mutants of a cold-adapted enzyme: insights into distal effects induced by the mutations |
| Q30821873 | Moritella cold-active dihydrofolate reductase: are there natural limits to optimization of catalytic efficiency at low temperature? |
| Q35113701 | MutT from the fish pathogen Aliivibrio salmonicida is a cold-active nucleotide-pool sanitization enzyme with unexpectedly high thermostability. |
| Q42055354 | Observed crowding effects on Mycobacterium tuberculosis 2-trans-enoyl-ACP (CoA) reductase enzyme activity are not due to excluded volume only |
| Q36748622 | Oligomerization as a strategy for cold adaptation: Structure and dynamics of the GH1 β-glucosidase from Exiguobacterium antarcticum B7. |
| Q27027749 | Optimization to low temperature activity in psychrophilic enzymes |
| Q35233581 | Protein surface softness is the origin of enzyme cold-adaptation of trypsin |
| Q37287783 | Psychrophilic enzymes: from folding to function and biotechnology |
| Q34307568 | Psychrophilic enzymes: hot topics in cold adaptation |
| Q33238599 | Psychrophilic microorganisms: challenges for life |
| Q46314609 | Purification and characterization of a psychrophilic catalase from Antarctic Bacillus |
| Q38030992 | Recent developments in production and biotechnological applications of cold-active microbial proteases |
| Q59270955 | Redox-regulated methionine oxidation of Arabidopsis thaliana glutathione transferase Phi9 induces H-site flexibility |
| Q44297997 | Regulation of arginine biosynthesis in the psychropiezophilic bacterium Moritella profunda: in vivo repressibility and in vitro repressor-operator contact probing |
| Q44785751 | Role of the second coordination sphere residue tyrosine 179 in substrate affinity and catalytic activity of phenylalanine hydroxylase |
| Q92927130 | Roles of Active-Site Aromatic Residues in Cold Adaptation of Sphingomonas glacialis Esterase EstSP1 |
| Q21142659 | Shewanella spp. genomic evolution for a cold marine lifestyle and in-situ explosive biodegradation |
| Q41656556 | Single amino acid mutation alters thermostability of the alkaline protease from Bacillus pumilus: thermodynamics and temperature dependence. |
| Q45100935 | Sodium chloride-induced modulation of the activity and thermal stability of short-chain oxidoreductase from the archaeon Thermococcus sibiricus. |
| Q35671851 | Some like it cold: biocatalysis at low temperatures. |
| Q27640129 | Stepwise adaptations of citrate synthase to survival at life's extremes. From psychrophile to hyperthermophile |
| Q43023101 | Structural adaptation to low temperatures--analysis of the subunit interface of oligomeric psychrophilic enzymes |
| Q33184993 | Structural and catalytic response to temperature and cosolvents of carboxylesterase EST1 from the extremely thermoacidophilic archaeon Sulfolobus solfataricus P1. |
| Q43033826 | Structural and functional adaptations to extreme temperatures in psychrophilic, mesophilic, and thermophilic DNA ligases |
| Q64106900 | Structural basis of small RNA hydrolysis by oligoribonuclease (CpsORN) from Colwellia psychrerythraea strain 34H |
| Q43023446 | Structural insights into cold inactivation of tryptophanase and cold adaptation of subtilisin S41. |
| Q42976155 | Structural stabilization and functional improvement of horseradish peroxidase upon modification of accessible lysines: experiments and simulation. |
| Q27645041 | Structure of phenylalanine hydroxylase from Colwellia psychrerythraea 34H, a monomeric cold active enzyme with local flexibility around the active site and high overall stability |
| Q43015504 | Structures and analysis of highly homologous psychrophilic, mesophilic, and thermophilic adenylate kinases |
| Q97520731 | Structures of fungal and plant acetohydroxyacid synthases |
| Q37705184 | Survey of the year 2008: applications of isothermal titration calorimetry |
| Q35841260 | Taxonomic characterization and the bio-potential of bacteria isolated from glacier ice cores in the High Arctic |
| Q51822935 | Temperature Adaptation of Proteins: Engineering Mesophilic-like Activity and Stability in a Cold-adapted α-Amylase |
| Q38297585 | Temperature Effects on Kinetic Parameters and Substrate Affinity of Cel7A Cellobiohydrolases. |
| Q37418619 | Temperature Sensitivity as a Microbial Trait Using Parameters from Macromolecular Rate Theory |
| Q33937757 | The active site is the least stable structure in the unfolding pathway of a multidomain cold-adapted alpha-amylase |
| Q42557982 | The cold denatured state of the C-terminal domain of protein L9 is compact and contains both native and non-native structure |
| Q27678029 | The complex structures of isocitrate dehydrogenase fromClostridium thermocellumandDesulfotalea psychrophilasuggest a new active site locking mechanism |
| Q39252614 | The linker region plays a key role in the adaptation to cold of the cellulase from an Antarctic bacterium |
| Q36966308 | The lysozyme from insect (Manduca sexta) is a cold-adapted enzyme |
| Q27651290 | The role of group bulkiness in the catalytic activity of psychrophile cold-active protein tyrosine phosphatase |
| Q37371966 | The thermolysin family (M4) of enzymes: therapeutic and biotechnological potential |
| Q48259460 | Thermodynamic and Structural Adaptation Differences between the Mesophilic and Psychrophilic Lactate Dehydrogenases. |
| Q92024697 | Towards Rational Computational Engineering of Psychrophilic Enzymes |
| Q57402051 | Tunneling in enzymatic and nonenzymatic hydrogen transfer reactions |
| Q44283150 | Water plays a different role on activation thermodynamic parameters of alcoholysis reaction catalyzed by lipase in gaseous and organic media. |
| Q43029735 | “Cold spots” in protein cold adaptation: Insights from normalized atomic displacement parameters (B′-factors) |