scholarly article | Q13442814 |
P2093 | author name string | Douglas D Boyd | |
Hua Lu | |||
Hongbo Wang | |||
Chunhong Yan | |||
Pingli Mo | |||
P2860 | cites work | Mdm2 promotes the rapid degradation of p53 | Q24322597 |
Oncoprotein MDM2 is a ubiquitin ligase E3 for tumor suppressor p53 | Q24328775 | ||
Regulation of p53 stability by Mdm2 | Q27860744 | ||
Surfing the p53 network | Q28032484 | ||
The ubiquitin ligase COP1 is a critical negative regulator of p53 | Q28258057 | ||
The mdm-2 oncogene product forms a complex with the p53 protein and inhibits p53-mediated transactivation | Q28280958 | ||
Activating transcription factor 3 is integral to the eukaryotic initiation factor 2 kinase stress response | Q28508156 | ||
APAF-1 is a transcriptional target of p53 in DNA damage-induced apoptosis | Q28609685 | ||
Rescue of embryonic lethality in Mdm2-deficient mice by absence of p53 | Q29614430 | ||
Rescue of early embryonic lethality in mdm2-deficient mice by deletion of p53 | Q29617850 | ||
ATF3 and stress responses. | Q33706914 | ||
Activating transcription factor 3 activates p53 by preventing E6-associated protein from binding to E6. | Q33800021 | ||
Stress signals utilize multiple pathways to stabilize p53 | Q33963268 | ||
ATF3 represses 72-kDa type IV collagenase (MMP-2) expression by antagonizing p53-dependent trans-activation of the collagenase promoter | Q34109489 | ||
Transcriptional activation of the human stress-inducible transcriptional repressor ATF3 gene promoter by p53. | Q34153744 | ||
ATF3 induction following DNA damage is regulated by distinct signaling pathways and over-expression of ATF3 protein suppresses cells growth | Q34155048 | ||
A self-enabling TGFbeta response coupled to stress signaling: Smad engages stress response factor ATF3 for Id1 repression in epithelial cells. | Q34193296 | ||
Induction of ATF3 by ionizing radiation is mediated via a signaling pathway that includes ATM, Nibrin1, stress-induced MAPkinases and ATF-2. | Q34209909 | ||
The p53-Mdm2 module and the ubiquitin system. | Q35036580 | ||
p53-independent activities of MDM2 and their relevance to cancer therapy | Q36047888 | ||
Systems biology approaches identify ATF3 as a negative regulator of Toll-like receptor 4. | Q38313431 | ||
Histone H3 acetylation and H3 K4 methylation define distinct chromatin regions permissive for transgene expression | Q38409875 | ||
Multiple C-terminal lysine residues target p53 for ubiquitin-proteasome-mediated degradation | Q39540070 | ||
Multiple lysine mutations in the C-terminal domain of p53 interfere with MDM2-dependent protein degradation and ubiquitination | Q39540284 | ||
BRCA1 and Tip60 determine the cellular response to ultraviolet irradiation through distinct pathways | Q39789468 | ||
MDM2 promotes p21waf1/cip1 proteasomal turnover independently of ubiquitylation | Q40323831 | ||
Activating transcription factor 3, a stress sensor, activates p53 by blocking its ubiquitination | Q40413949 | ||
Fluorescent cDNA microarray hybridization reveals complexity and heterogeneity of cellular genotoxic stress responses. | Q40946010 | ||
Role for activating transcription factor 3 in stress-induced beta-cell apoptosis | Q41296267 | ||
The regulation of ATF3 gene expression by mitogen-activated protein kinases | Q42104816 | ||
Repression of 92-kDa type IV collagenase expression by MTA1 is mediated through direct interactions with the promoter via a mechanism, which is both dependent on and independent of histone deacetylation | Q42527855 | ||
Activating transcription factor 3, a stress-inducible gene, suppresses Ras-stimulated tumorigenesis | Q46937302 | ||
Regulation of the p53 protein by the MDM2 oncoprotein--thirty-eighth G.H.A. Clowes Memorial Award Lecture | Q48379741 | ||
ATF3 regulates the stability of p53: a link to cancer | Q53626549 | ||
Transcriptional autorepression of the stress-inducible gene ATF3 | Q73626798 | ||
Dual-site regulation of MDM2 E3-ubiquitin ligase activity | Q79954190 | ||
Transcription - guarding the genome by sensing DNA damage | Q80518102 | ||
P433 | issue | 35 | |
P407 | language of work or name | English | Q1860 |
P921 | main subject | protein ubiquitination | Q3547638 |
P304 | page(s) | 26908-26915 | |
P577 | publication date | 2010-06-30 | |
P1433 | published in | Journal of Biological Chemistry | Q867727 |
P1476 | title | MDM2 mediates ubiquitination and degradation of activating transcription factor 3 | |
P478 | volume | 285 |
Q35095241 | A Small-Molecule p53 Activator Induces Apoptosis through Inhibiting MDMX Expression in Breast Cancer Cells |
Q41098388 | Activating Transcription Factor 3 and the Nervous System |
Q53182665 | Activating transcription factor 3 SUMOylation is involved in angiotensin II-induced endothelial cell inflammation and dysfunction |
Q50225374 | Atf3 deficiency promotes genome instability and spontaneous tumorigenesis in mice |
Q91657624 | Competitive ubiquitination activates the tumor suppressor p53 |
Q90010524 | Deleting key autophagy elongation proteins induces acquirement of tumor-associated phenotypes via ISG15 |
Q40629780 | Emerging roles of ATF3 in the suppression of prostate cancer |
Q39165172 | Loss of SUMOylation on ATF3 inhibits proliferation of prostate cancer cells by modulating CCND1/2 activity |
Q28271894 | MDM2 Associates with Polycomb Repressor Complex 2 and Enhances Stemness-Promoting Chromatin Modifications Independent of p53 |
Q38149734 | MDM2's social network |
Q33788018 | Mdm2 links genotoxic stress and metabolism to p53 |
Q53182297 | Nanog regulates molecules involved in stemness and cell cycle-signaling pathway for maintenance of pluripotency of P19 embryonal carcinoma stem cells |
Q53160111 | Polymorphisms in TP53 and MDM2 contribute to higher risk of colorectal cancer in Chinese population: a hospital-based, case-control study |
Q64086789 | Regulatory mechanisms of fluvastatin and lovastatin for the p21 induction in human cervical cancer HeLa cells |
Q39023830 | Role of activating transcription factor 3 protein ATF3 in necrosis and apoptosis induced by 5-fluoro-2'-deoxyuridine |
Q39275947 | SUMOylation of ATF3 alters its transcriptional activity on regulation of TP53 gene |
Q37424099 | The Hsp90 inhibitor 17-(allylamino)-17-demethoxygeldanamycin increases cisplatin antitumor activity by inducing p53-mediated apoptosis in head and neck cancer |
Q41287020 | The Many Faces of MDM2 Binding Partners |
Q39336988 | The Stress Response Mediator ATF3 Represses Androgen Signaling by Binding the Androgen Receptor |
Q36898296 | The Stress-responsive Gene ATF3 Mediates Dichotomous UV Responses by Regulating the Tip60 and p53 Proteins. |
Q37691694 | The activating transcription factor 3 protein suppresses the oncogenic function of mutant p53 proteins |
Q36008822 | The common stress responsive transcription factor ATF3 binds genomic sites enriched with p300 and H3K27ac for transcriptional regulation |
Q34995975 | The induction of activating transcription factor 3 (ATF3) contributes to anti-cancer activity of Abeliophyllum distichum Nakai in human colorectal cancer cells |
Q38888300 | The stress-responsive gene ATF3 regulates the histone acetyltransferase Tip60. |
Q58771668 | Trans-chalcone increases p53 activity via DNAJB1/HSP40 induction and CRM1 inhibition |
Q38967025 | XI-011 enhances cisplatin-induced apoptosis by functional restoration of p53 in head and neck cancer |
Search more.