Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats

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Activation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats is …
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scholarly articleQ13442814

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P6179Dimensions Publication ID1017632427
P356DOI10.1186/1744-8069-6-49
P932PMC publication ID2936374
P698PubMed publication ID20796319
P5875ResearchGate publication ID46008567

P2093author name stringLei Tan
Wen Xu
Kewei Wang
Yuwei Wu
Yehua Gan
Yeping Bi
P2860cites workEffects of retigabine (D-23129) on different patterns of epileptiform activity induced by low magnesium in rat entorhinal cortex hippocampal slices.Q52974740
D-23129: a new anticonvulsant with a broad spectrum activity in animal models of epileptic seizures.Q53989493
Muscarinic suppression of a novel voltage-sensitive K+ current in a vertebrate neuroneQ59066538
Correlation between pain and synovitis in patients with internal derangement of the temporomandibular jointQ68044114
Meal pattern analysis in response to temporomandibular joint inflammation in the ratQ73052156
An improved method for assessing mechanical allodynia in the ratQ73289147
The role of pharmacy in the management of patients with temporomandibular disorders and orofacial painQ74758733
Analgesic action of gabapentin on chronic pain in the masticatory muscles: a randomized controlled trialQ79214186
Kv7.2-7.5 voltage-gated potassium channel (KCNQ2-5) opener, retigabine, reduces capsaicin-induced visceral pain in miceQ79447473
Inflammatory cell and cytokine patterns in patients with chronic polyarthritis and temporomandibular joint involvementQ79864059
Activation of NK1 receptor of trigeminal root ganglion via substance P paracrine mechanism contributes to the mechanical allodynia in the temporomandibular joint inflammation in ratsQ81901385
KCNQ2 and KCNQ3 potassium channel subunits: molecular correlates of the M-channelQ22008501
A potassium channel mutation in neonatal human epilepsyQ24320244
Neural KCNQ (Kv7) channelsQ24644947
New molecular targets for antiepileptic drugs: alpha(2)delta, SV2A, and K(v)7/KCNQ/M potassium channelsQ24654230
Characterization of KCNQ5/Q3 potassium channels expressed in mammalian cellsQ24674102
A pore mutation in a novel KQT-like potassium channel gene in an idiopathic epilepsy familyQ28115034
The novel anticonvulsant retigabine activates M-currents in Chinese hamster ovary-cells tranfected with human KCNQ2/3 subunitsQ28138343
KCNQ5, a novel potassium channel broadly expressed in brain, mediates M-type currentsQ28144661
The contribution of neuroimaging techniques to the understanding of supraspinal pain circuits: implications for orofacial painQ33222276
Modulation and genetic identification of the M channelQ34013683
The new anticonvulsant retigabine (D-23129) acts as an opener of K+ channels in neuronal cellsQ34447899
M-channels: neurological diseases, neuromodulation, and drug development.Q35111665
Why look in the brain for answers to temporomandibular disorder pain?Q36222734
Pharmacologic management of temporomandibular disordersQ37111070
Evidence for up-regulated central nociceptive processing in patients with masticatory myofascial painQ39679170
KCNQ4 channel activation by BMS-204352 and retigabineQ40802799
Identifying a neurobiologic basis for drug therapy in TMDsQ40993983
The influence of neuropeptides, serotonin, and interleukin 1beta on temporomandibular joint pain and inflammationQ41699881
M channel KCNQ2 subunits are localized to key sites for control of neuronal network oscillations and synchronization in mouse brain.Q42513993
Correlation between arthroscopic diagnosis of osteoarthritis and synovitis of the human temporomandibular joint and keratan sulfate levels in the synovial fluidQ42550967
17-Beta-estradiol enhanced allodynia of inflammatory temporomandibular joint through upregulation of hippocampal TRPV1 in ovariectomized ratsQ42997878
Retigabine reduces the excitability of unmyelinated peripheral human axonsQ43556539
The temporomandibular joint: a comparison of clinical and arthroscopic findingsQ43944655
The anticonvulsant retigabine attenuates nociceptive behaviours in rat models of persistent and neuropathic painQ44297459
Meal pattern changes associated with temporomandibular joint inflammation/pain in rats; analgesic effectsQ44448596
KCNQ/M currents in sensory neurons: significance for pain therapy.Q44540560
The anti-hyperalgesic activity of retigabine is mediated by KCNQ potassium channel activationQ44791007
Pharmacological characterisation of acid-induced muscle allodynia in ratsQ44806856
Urodynamic effects of the K+ channel (KCNQ) opener retigabine in freely moving, conscious ratsQ45148624
Meclofenamic acid and diclofenac, novel templates of KCNQ2/Q3 potassium channel openers, depress cortical neuron activity and exhibit anticonvulsant propertiesQ45187314
Conditional transgenic suppression of M channels in mouse brain reveals functions in neuronal excitability, resonance and behavior.Q45194025
Temporomandibular joint inflammation potentiates the excitability of trigeminal root ganglion neurons innervating the facial skin in ratsQ45206248
Diclofenac sodium and occlusal splint therapy in TMJ osteoarthritis: a randomized controlled trialQ46594121
Estrogenic effect on swelling and monocytic receptor expression in an arthritic temporomandibular joint model.Q46695555
Retigabine, the specific KCNQ channel opener, blocks ectopic discharges in axotomized sensory fibresQ46709221
Enhanced excitability of rat trigeminal root ganglion neurons via decrease in A-type potassium currents following temporomandibular joint inflammationQ46874908
Immunohistochemical analysis of KCNQ3 potassium channels in mouse brainQ46972610
P921main subjectvoltageQ25428
inflammationQ101991
P304page(s)49
P577publication date2010-08-27
P1433published inMolecular PainQ15766244
P1476titleActivation of voltage-gated KCNQ/Kv7 channels by anticonvulsant retigabine attenuates mechanical allodynia of inflammatory temporomandibular joint in rats
P478volume6

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cites work (P2860)
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